Clinical trials: Cervix
Cervix Cancer, Radiotherapy, Adjuvant
Postoperative Hypofractionated Intensity-modulated Radiation Therapy in Cervical Cancer
To investigate the acute toxicities, late toxicities, and treatment results when the early cervical cancer patients are treated by hypofractionated intensity-modulated radiotherapy (2.5 Gy X 16 fractions, once a day) after…
- Conditions
- Cervix Cancer, Radiotherapy, Adjuvant, Radiotherapy, Intensity-Modulated, Hypofractionated Dose
- Trial name
- NCT03239626
- Testing
- POHIM-RT
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Cervix Cancer, Endometrial Cancer
Prognostic and Diagnostic Added Value of Medical Imaging in Gynecological Cancer (PRODIGYN)
The goal of this observational study is to learn about the added diagnostic and prognostic value of advanced medical imaging procedures in cervical cancer, endometrial cancer and ovarian cancer.
- Conditions
- Cervix Cancer, Endometrial Cancer, Epithelial Ovarian Cancer
- Trial name
- PRODIGYN (NCT05855941)
- Testing
- FDG-PET/CT and FDG-PET/MRI
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Region Västerbotten
Cervix Cancer
COL Immunotherapy Before Radiochimio + Ipilimumab
This is a multicenter, single arm pilot study evaluating the biological impact of "Nivolumab + Ipilimumab" in patients with cervical squamous cell carcinoma requiring RT-CT as initial therapy
- Trial name
- COLIBRI (NCT04256213)
- Testing
- Nivolumab and Ipilimumab
- Where
- 8 sites in France
- Volunteers
- 40 people
- Sponsor
- ARCAGY/ GINECO GROUP
Stage III Breast Cancer, Stage IV Breast Cancer
Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to Drugs
The primary objective of this study, sponsored by Travera in Massachusetts, is to validate whether the mass response biomarker has potential to predict response of patients to specific therapies or therapeutic combinations using…
- Conditions
- Stage III Breast Cancer, Stage IV Breast Cancer, Stage III Lung Cancer, Stage IV Lung Cancer
- Trial name
- NCT04985357
- Sponsor
- Travera Inc
Pelvic Organ Prolapse, Prolapse
A New POP (Pelvic Organ Prolapse) Scoring System: Validity and Reliability
There is a strong need for a better, simplified and informative applicable classification system that should be used to speak a common descriptive language among health care providers that treat POP.
- Conditions
- Pelvic Organ Prolapse, Prolapse, Prolapse, Vaginal, Prolapse Uterus
- Trial name
- NCT06520722
- Testing
- Prolapse scoring system
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Cervix Lesion, Cervical Cancer
Application of Plasma Circulating HPV DNA Testing to Management of Cervical Intraepithelial Neoplasia
The purpose of this study is to see if circulating HPV DNA (cHPVDNA) can be used as a noninvasive biomarker for cervical intraepithelial neoplasia (CIN) 2-3 in hopes of reducing procedures and costs for patients, as well as…
- Trial name
- NCT04274465
- Testing
- digital PCR (dPCR) assay
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cancer Cervix
Role Of Colposcopy In Evaluation Of Suspicious Cervix
do colposcopy and cervical punch biopsy then compare between findings
- Trial name
- NCT06673680
- Testing
- Do colposcopy and cervical punch biopsy then compare between findings
- Where
- Egypt
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cervical Cancer, Cervix Cancer
Minimally Invasive Simple Hysterectomy in Low Risk Cervical Cancer
The rationale of the present study is to assess the safety of the minimally invasive surgery approach in patients meeting the SHAPE trial inclusion criteria.The SHAPE trial was designed to answer the clinical question of whether…
- Trial name
- LASH (NCT06416748)
- Testing
- Minimally invasive simple hysterectomy
- Where
- Italy
- Volunteers
- 974 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cervix Cancer
Prevalence of Abnormal Pap Smear
This study aims to evaluate prevalence of abnormal Pap smear among sexually active women of reproductive age attending sohag university hospital outpatient clinic.
- Trial name
- NCT06641531
- Testing
- Screening pap smear test
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cancer of Cervix
Follow-up of Cell Changes in the Cervix
The purpose of the study is to follow up on cell changes detected in the cervical cancer screening program, to investigate whether they are handled with adequate quality.
- Trial name
- NCT05709730
- Testing
- HPV genotyping
- Where
- Sweden
- Volunteers
- 885 people
- Sponsor
- Karolinska University Hospital
Endometrial Carcinoma, Cervix Carcinoma
GYNecological Cancers Treated with NETrin MAbs in Combination with Chemotherapy and /or Pembrolizumab
The aim of this study is to investigate the safety and the clinical activities of NP137 when combined with pembrolizumab and/or chemotherapies in patients with advanced/metastatic gynecological cancers (2 types: endometrial…
- Trial name
- GYNET (NCT04652076)
- Testing
- NP137, Pembrolizumab, Paclitaxel
- Where
- 15 sites in France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- NETRIS Pharma
Cancer-associated Thrombosis, Venous Thromboembolism
The Gynecological Cancer Associated Thrombosis (GynCAT) Study
GynCAT is a prospective cohort study that will be conducted on female patients with gynecologic malignancies scheduled for systemic antineoplastic treatment, aiming at development and validation of a Risk Assessment Model (RAM)…
- Conditions
- Cancer-associated Thrombosis, Venous Thromboembolism, Gynecologic Cancer, Ovarian Cancer
- Trial name
- GynCAT (NCT06284343)
- Testing
- Anticoagulant
- Where
- Italy
- Volunteers
- 1,800 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Endometrium; Hypertrophy, Cervix, Anesthesia
High Flow Oxygen During Operative Hysteroscopy.
High-flow nasal cannula (HFNC) oxygen therapy represents an open circuit ventilation system that uses flows up to 70 L/min of 100% oxygen through the Optiflow THRIVETM device (Fisher and Paykel Healthcare Ltd, Auckland, New…
- Conditions
- Endometrium; Hypertrophy, Cervix, Anesthesia, Apnea, Postanesthetic
- Trial name
- HOPE (NCT05550584)
- Testing
- Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE)., LMA
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Metastatic Carcinoma of the Cervix
Study of Niraparib With Radiotherapy for Treatment of Metastatic Invasive Carcinoma of the Cervix
The most effective strategy for managing distantly metastatic invasive carcinomas of the cervix is not defined. Based on the success of niraparib in breast and ovarian cancer trials and the concern for toxicities and…
- Trial name
- NIVIX (NCT03644342)
- Testing
- Nirapaib
- Where
- 3 sites in United States
- Volunteers
- 4 people
- Sponsor
- Michelle S Ludwig
Cervical Cancer, Cervix Neoplasm
Screening for Early Cervical Cancer Detection
This study is to audit results and adherence to Cervical Screening program before and after the implementing awareness of the WHO guidelines of screening among the multidisciplinary healthcare workers and patients.
- Trial name
- NCT06550583
- Testing
- Pap smear /Test
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Radiation Therapy, Cancer
Radiotherapy Assessments During Intervention ANd Treatment (RADIANT)
Collect blood samples and associated clinical data prior to, during, and post radiation treatment.
- Conditions
- Radiation Therapy, Cancer, Cancer of Anus, Cancer of Bladder
- Trial name
- RADIANT (NCT03133286)
- Where
- 4 sites in United States
- Volunteers
- 16 people
- Sponsor
- DxTerity Diagnostics
Cervix Cancer, Human Papilloma Virus
Relational Agents in Cervical Cancer Education (RACE)
The goal of this clinical trial is to assess the feasibility of using interactive teaching to educate cervical cancer patients about Human papillomavirus (HPV) and HPV vaccinations.
- Conditions
- Cervix Cancer, Human Papilloma Virus, Vaginal Cancer, Vulvar Cancer
- Trial name
- RACE (NCT06537687)
- Testing
- Control, Intervention
- Where
- 2 sites in United States
- Volunteers
- 91 people
- Sponsor
- Radhika Gogoi
Cervical Cancer, Cervix Cancer
Adjuvant Chemotherapy in cfHPV-DNA Plasma Positive Patients: A Biomarker In Locally Advanced Cervical Cancer
This study hypothesizes that patients who persist with cell-free human papillomavirus deoxyribonucleic acid (cfHPV-DNA) plasma expression at the end of standard treatment, can derive the benefit of using adjuvant chemotherapy in…
- Conditions
- Cervical Cancer, Cervix Cancer, Cervix Neoplasm
- Trial name
- AddChemo (NCT05764044)
- Testing
- cisplatin, gemcitabine, Follow-up
- Where
- 26 sites in Brazil
- Volunteers
- 365 people
- Sponsor
- Hospital do Coracao
Malnutrition; Protein, Cancer, Lung
Effect of NUTRICAN to Improve Nutritional Status in Cancer Patients
The goal of this clinical trial is to evaluate the efficacy oral nutrition supplement (ONS) in malnutrition/high risk malnutrition cancer patients. The main questions it aims to answer: 1.
- Conditions
- Malnutrition; Protein, Cancer, Lung, Cancer Cervix
- Trial name
- NCT06128694
- Testing
- NUTRICAN
- Where
- Indonesia
- Volunteers
- 108 people
- Sponsor
- Kalbe International Pte. Ltd
Cancer of Cervix, HPV Infection
The Effect of Education Given to Women on Cervical Cancer on Knowledge, Attitude and Belief
Aim: The aim of this study is to reveal the effect of education given to women about cervical cancer on knowledge, attitude and belief.
- Trial name
- EEWCCKAB (NCT05990270)
- Testing
- education
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University