Clinical trials: Cervix Carcinoma
HPV, HPV Associated Cancers
Emergency Department-based Cervical Cancer Screening Through Self-sampling
This project will compare the uptake of cervical cancer screening through ED HPV sampling among patients presenting to the ED.
- Conditions
- HPV, HPV Associated Cancers, HPV Cancers, Cervical Cancer Screening
- Trial name
- NCT07345897
- Testing
- Cervical Cancer Screening
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Cervical Cancer
Intervention to Improve Follow-up of Abnormal Pap Test
This project will examine whether a theory-based telephone intervention delivered by a nurse at the time women are informed of an abnormal Pap test result will increase adherence to follow-up recommendations.
- Trial name
- NCT00575510
- Testing
- Intervention, Active control
- Where
- United States
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Squamous Cell Lung Cancer, Vulvar Cancer
Efficacy of Immunotherapy Plus a Drug in Patients With Progressive Advanced Mucosal Cancer of Different Locations
Interventional study evaluating the efficacy of an immunotherapy (pembrolizumab) in combination with a targeted therapy (vorinostat) in patient with recurrent and/or metastatic squamous cell carcinoma (localisations : head and…
- Conditions
- Squamous Cell Lung Cancer, Vulvar Cancer, Penile Cancer, Cervix Cancer
- Trial name
- PEVOsq (NCT04357873)
- Testing
- pembrolizumab; vorinostat
- Where
- 14 sites in France
- Volunteers
- 112 people
- Sponsor
- UNICANCER
Uterine Cervical Neoplasms, Surgery
Gastric-type Endocervical Adenocarcinoma: a Population-based Cohort Study
This study aims to collect data of patients with Gastric-type Endocervical Adenocarcinoma from the SEER database, analyze the related prognostic factors and treatment patterns of Gastric-type Endocervical Adenocarcinoma, and…
- Conditions
- Uterine Cervical Neoplasms, Surgery, Therapy, Locally Advanced Cervical Carcinoma
- Trial name
- NCT06897306
- Testing
- surgery
- Where
- China
- Volunteers
- 317 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Cervical Intraepithelial Neoplasia Grade 2/3, Carcinoma Cervix
Extended VALidation of HUman Papillomavirus Assays and Collection DEvices for HPV Testing on Self-samples
The "Extended VALHUDES" study is a Clinical Performance / Diagnostic Test Accuracy Study that aims to extend validation, achieved as part of the "Belgian VALHUDES", of HPV testing using BD Onclarity on samples collected using…
- Trial name
- Ext-VALHUDES (NCT04788849)
- Testing
- BD Onclarity™ HPV assay
- Where
- 2 sites in Italy
- Volunteers
- 300 people
- Sponsor
- University of Milano Bicocca
Cervical Cancer
Detection of Loco-regional Invasion of Cervical Cancer With 7 Tesla MRI
Background of the study: The accurate assessment of local cervical cancer spread (i.e. invasion) is of clinical importance for staging and treatment considerations.
- Trial name
- DETECT (NCT02083848)
- Testing
- 7T MRI
- Where
- Netherlands
- Volunteers
- 23 people
- Sponsor
- UMC Utrecht
Cervical Cancer, HPV Infection
Re-Evaluation of Annual Cytology Using HPV Testing to Upgrade Prevention in Women Living With HIV
Current British HIV Association (BHIVA) guidelines recommend annual cervical screening (with a cervical smear) for women living with HIV (WLWH). NHS guidelines for women in England will, however, change soon.
- Conditions
- Cervical Cancer, HPV Infection, HIV Infections
- Trial name
- REACH-UP (NCT04155294)
- Where
- 6 sites in United Kingdom
- Volunteers
- 71 people
- Sponsor
- University of Oxford
Ovarian Sarcoma, Ovarian Stromal Cancer
Psychosexual Intervention in Patients With Stage I-III Gynecologic or Breast Cancer
This randomized phase II trial studies how well psychosexual intervention works in patients with stage I-III gynecologic or breast cancer. Psychosexual intervention may improve sexual and psychosocial function.
- Conditions
- Ovarian Sarcoma, Ovarian Stromal Cancer, Stage I Uterine Sarcoma, Stage I Vaginal Cancer
- Trial name
- NCT01764802
- Testing
- behavioral, psychological or informational intervention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cervical Cancer
Community-Based Cervical Cancer Prevention and Education Among Women Living With HIV
The long-term goal is to build a sustainable, community-based outreach program to promote cervical cancer screening among women living with HIV (WLH), thereby reducing related morbidity and mortality.
- Trial name
- CHECC-uP (NCT03033888)
- Testing
- Health-Literacy Focused Education Session
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Johns Hopkins University
Cancer
Mobile Health Application Developed for Cervical Cancer
The main purpose of this research is to evaluate the effect of the nursing care that participants receive with the mobile health application for cervical cancer on raising awareness about cervical cancer.
- Trial name
- NCT05378542
- Testing
- Mobile application usage
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Gazi University
Cervical Cancer
Significance of Fluorescence Colposcopy With Autofluorescence Imaging for Cervical Cancer
Clinical Trial to access Significance of fluorescence colposcopy with autofluorescence imaging for the screening of cervical cancer
- Trial name
- NCT01854983
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Cervix Cancer
A Study of Pembrolizumab And Platinum With Radiotherapy in Cervix Cancer
Locally advanced cervix cancers (stage 1B-IV) are usually treated with radiotherapy, concomitant cisplatin chemotherapy and brachytherapy.
- Trial name
- PAPAYA (NCT03144466)
- Testing
- Pembrolizumab
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Cervical Cancer, Precancerous Condition
Imiquimod in Preventing Cervical Cancer in Women With Cervical Neoplasia
RATIONALE: Chemoprevention therapy is the use of certain substances to try to prevent the development of cancer. Applying topical imiquimod before abnormal cervical cells are removed may be effective in preventing cervical…
- Trial name
- NCT00031759
- Testing
- imiquimod, Ablative or excisional therapy
- Where
- 8 sites in United States
- Volunteers
- 57 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Locally Advanced Cervical Cancer
Curcumin Supplementation in Cervical Cancer
Brief Summary. The goal of this pilot study is to learn about the effect of curcumin supplementation in locally advanced cervical cancer patients.
- Trial name
- NCT06080841
- Testing
- Curcumin, Curcumin + Piperine
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- National Institute of Cancerología
Stage IIIC
Stereotactic Body Radiotherapy Boost Versus Simultaneous Integrated Boost to Pelvic Nodes Among Patients Receiving Radical Chemoradiation in Carcinoma Cervix
Cervical cancer is a significant cause of morbidity and mortality among women worldwide. Radiotherapy, in combination with chemotherapy or as a standalone treatment, is an effective treatment option for cervical cancer.
- Trial name
- NCT07585929
- Testing
- Stereotactic Body Radiotherapy Boost to Involved Pelvic Lymph Nodes, Standard Arm: Simultaneous Integrated Boost to involved pelvic node
- Where
- 3 sites in India
- Volunteers
- 150 people
- Sponsor
- All India Institute of Medical Sciences
Advanced Solid Tumor, Metastatic Solid Tumor
A Study of IDP-001 in Advanced or Metastatic Solid Tumors
This clinical study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of IDP-001 in participants with advanced or metastatic squamous and non-squamous NSCLC and other squamous cell…
- Conditions
- Advanced Solid Tumor, Metastatic Solid Tumor, Head and Neck Squamous Cell Carcinoma, Cutaneous Squamous Cell Carcinoma
- Trial name
- NCT07602842
- Testing
- IDP-001
- Where
- 6 sites in United States
- Volunteers
- 132 people
- Sponsor
- InduPro, Inc.
Cervical Cancer, High Grade Sil
Screening Study for Cervical Pre-cancer and Cancer Prevention in South African Women.
Nearly 8 000 new cervical cancer cases are diagnosed in South Africa per year; many are still undiagnosed and about 50% of diagnosed cases succumb per year.
- Conditions
- Cervical Cancer, High Grade Sil, CIN2
- Trial name
- DiaVACCS (NCT02956031)
- Testing
- Screening, Colposcopy, LLETZ
- Where
- South Africa
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Pretoria
Cancer
OX-40 Protein Expression in the Sentinel Lymph Nodes of Patients With Cancer
RATIONALE: Studying protein expression in sentinel lymph node tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
- Trial name
- NCT00900302
- Testing
- protein expression analysis, immunohistochemistry staining method, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- OHSU Knight Cancer Institute
Human Papillomavirus
Alinity m HR HPV Specimen Collection Study From Women Undergoing Routine Cervical Cancer Screening
A prospective multicenter interventional study will be conducted to enroll women undergoing routine cervical cancer screening to collect cervical liquid-based cytology (LBC) specimen(s).
- Trial name
- NCT04746872
- Testing
- Alinity m HR HPV
- Where
- 63 sites in United States
- Volunteers
- 14,935 people
- Sponsor
- Abbott Molecular
Cervical Cancer, Behavior
Reducing Barriers and Sustaining Utilization of a Cervical Cancer Screening Program in Rural Senegal
This research project will investigate the determinants of cervical cancer screening uptake and sustained utilization in this region and develop and evaluate a context-specific peer education behavioral intervention to improve…
- Trial name
- NCT03540069
- Testing
- Care Group Cervical Cancer Screening Education Curriculum
- Where
- 3 sites in United States, Senegal
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago