Clinical trials: Cesarean Sections
Uterine Scar
Assessment of Single and Double Layer Suturation of Lower Segment Uterine Incision by USG After C/S
After 6 months of cesarean delivery, the investigators will compare uterine incision scar defects of single and double layer suturation of uterine incision by transvaginal ultrasonography.
- Trial name
- NCT03676907
- Testing
- double layer suturation technique
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Gazi University
Uterine Atony, Post-partum Hemorrhage
Comparison of Two Doses of Carbetocin for Prevention of Uterine Atony, During Elective Cesarean Section
The purpose of this study is to evaluate the effectiveness of two doses of carbetocin (50 mcg vs 100 mcg) in preventing uterine atony during elective cesarean section.
- Trial name
- NCT01630187
- Testing
- Carbetocin
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Laval University
Pruritus Caused by Drug
Comparison of Pruritus Incidence After Intrathecal Morphine 0.1 vs 0.2 mg in Cesarean Section
This study compares the incidence of pruritus (itching) requiring treatment between two doses of intrathecal morphine (0.1 mg vs 0.2 mg) when used for spinal anesthesia during cesarean section.
- Trial name
- NCT07054775
- Testing
- Morphine Sulfate
- Where
- 2 sites in Thailand
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Postoperative Pain
The Effect of Quran of Post Operative Pain
Postoperative pain management is crucial for surgical patients. Management of postoperative pain entails reducing painful symptoms, improving the quality of recovery and resuming normal daily living activities.
- Trial name
- NCT02589834
- Testing
- Quran group
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Assiut University
Preoperative Anxiety, Cesarean Section
Effect of Video-Based Versus Verbal Preoperative Information on Anxiety and Cortisol Levels in Elective Cesarean Section
Preoperative anxiety is a common problem in patients undergoing elective cesarean section and may negatively affect perioperative outcomes through activation of the stress response, including increased cortisol levels.
- Conditions
- Preoperative Anxiety, Cesarean Section, Surgical Stress Response, Cortisol
- Trial name
- NCT07521592
- Testing
- Verbal Preoperative Information, Video-Based Preoperative Information
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Hypotension
Hemodynamic Monitoring in Obstetrics
Spinal anesthesia has long been considered the first choice technique in caesarean section, but although it is a reliable and safe procedure, it is in some cases associated with undesirable effects.
- Trial name
- NCT03755271
- Where
- Italy
- Volunteers
- 148 people
- Sponsor
- University of Catania
Postpartum Hemorrhage, Systemic Autoimmune Diseases
Prophylactic Tranexamic Acid Reduces Postpartum Hemorrhage
Postpartum hemorrhage (PPH) is the most significant leading cause of pregnancy-related mortality in high-risk cesarean delivery women.
- Trial name
- NCT06754371
- Testing
- tranexamic acid, normal saline
- Where
- China
- Volunteers
- 276 people
- Sponsor
- RenJi Hospital
Surgical Wound Dehiscence, Wound Infection
Prevention of Wound Complications After Cesarean Delivery in Obese Women Utilizing Negative Pressure Wound Therapy
Wound complications after Cesarean section (C-section) are common in obese women. Approximately 25% of obese women having a C-section will have a wound complication.
- Trial name
- NCT00654641
- Testing
- Negative pressure wound closure, Standard wound closure
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- West Virginia University
Low Back Pain, Cesarean Section Complications
Osteopathic Manipulations of Post Cesarean Section Adhesions on Low Back Pain
Chronic low back pain post cesarean section adhesions represents a restricting dysfunction, mainly influences abdominal fascia that leads to major welfare and economic restrictions.
- Trial name
- NCT06907394
- Testing
- Osteopathic Manipulations, Control Group
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Neonatal Hypoglycemia
Immediate Skin-To-Skin Contact and Early Breastfeeding During Caesarean Section
Background: Neonatal hypoglycemia is a prevalent and serious condition among late preterm and term infants, which can lead to severe neurodevelopmental consequences if not managed properly.
- Trial name
- NCT06543160
- Testing
- Immediate SSC and early breastfeeding during CS, Delayed SSC and breastfeeding after CS, Routine newborn care
- Where
- China
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Qingdao Municipal Hospital
Abdominal Muscles/Ultrasonography, Adult
TAP Catheters Versus Intrathecal Morphine for Cesarean Section
Morphine, when given as part of spinal anesthesia, is associated high incidence of nausea and pruritus, which may affect quality of recovery.
- Conditions
- Abdominal Muscles/Ultrasonography, Adult, Anesthetics, Local/Administration & Dosage, Ropivacaine/Administration & Dosage
- Trial name
- NCT01593280
- Testing
- TAP catheter, intrathecal morphine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stamford Anesthesiology Services, PC
Pre Eclampsia, Eclampsia, Antepartum
BH4 Blood Levels Variations in Pre Eclamptic Women
tetrahydrobiopterin (BH4) is degraded by several enzymes, including BH4 oxidase and peroxidases. Several factors can affect its synthesis and degradation.
- Conditions
- Pre Eclampsia, Eclampsia, Antepartum, HELLP Syndrome (HELLP), Unspecified Trimester, Acute Renal Failure
- Trial name
- BH4P (NCT05847361)
- Testing
- BH4 blood level
- Where
- Tunisia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Postoperative Pain
Bilateral Erector Spinae Plane Block After Elective Cesarean Section
The aim of work is to assess and compare the analgesic efficacy of bilateral erector spinae plane block with that of bilateral transversus abdominis plane block after elective cesarean section.
- Trial name
- NCT04016688
- Testing
- ESPB and TAP block
- Where
- 3 sites in Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Cardiac Output, Hypotension
Cardiac Output Changes During Hyperbaric and Isobaric Bupivacaine in Patients Undergoing Cesarean Section
Spinal block leads to the reduction of systemic vascular resistance (SVR) which may effect the cardiac output. Ngan Kee et al. has showed that spina block with 0.5% hyperbaric bupivacaine for Cesarean section combined with…
- Conditions
- Cardiac Output, Hypotension, Anesthesia, Spinal
- Trial name
- NCT02737813
- Testing
- Isobaric marcaine, Hyperbaric marcaine
- Where
- Thailand
- Volunteers
- 168 people
- Sponsor
- Mahidol University
Prenatal Care Late, Cesarean Delivery Affecting Fetus
The Effect of Prenatal Education on Primary Cesarean Rate
This is a prospective case-control study examining the impact of antenatal education on mode of delivery. The study will include all deliveries occurring between January 2024 and December 2024.
- Trial name
- NCT06844188
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Sanliurfa Education and Research Hospital
Pregnancy Related, Cesarean Section Complications
Predictive Hemodynamic Monitoring During Elective Cesarean Section
Single shot spinal anesthesia (SA) is the most commonly used technique for Caesarean section (CS) . SA is associated with maternal hypotension (Post Spinal Hypotension - PSH) often accompanied by nausea, vomiting, bradycardia and…
- Conditions
- Pregnancy Related, Cesarean Section Complications, Hypotension on Induction, Anesthesia Complication
- Trial name
- PREDICTION (NCT06729827)
- Testing
- Hypotension prediction Index - HPI
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Surgical Site Infection
Betadine Versus Saline in Swapping of Subcutaneous Tissue
Caesarean section is an increasingly common major surgical procedure performed on women. Last decade an overall increase of the global rate of caesarean section, of up to 31.2%, was reported.
- Trial name
- NCT06595823
- Testing
- Betadine
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Egymedicalpedia
Cesarean Section Complications, Hemodynamic Instability
Norepinephrine in Caesarian Section
Postspinal hypotension is a frequent maternal complication in caesarian delivery under neuraxial anesthesia which is most commonly treated with the administration of phenylephrine infusion.
- Conditions
- Cesarean Section Complications, Hemodynamic Instability, Foetal Stress
- Trial name
- NCT05264870
- Testing
- Norepinephrine
- Where
- Belgium
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Body Temperature Measurement
Continuous Monitoring of Body Temperature in Neonates During Skin-to-skin Care Immediately After Cesarean Section (MonT Neo)
The objective of this prospective observational pilot study is to apply the adhesive thermometer SteadyTemp® (SteadySense GmbH, Graz, Austria) in term neonates to monitor their body temperature non-invasively and continuously…
- Trial name
- MonT Neo (NCT06632769)
- Testing
- No intervention
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Hypotension in Pregnant Women, Headache in Pregnant Women
Prediction of Hypotension and Postdural Puncture Headache by Carotid Artery Corrected Flow Time
Anesthesia for cesarean delivery can be provided through general or neuraxial anesthesia (spinal or epidural). Hypotension is a common complication of both methods.
- Trial name
- NCT07372313
- Volunteers
- 90 people
- Sponsor
- TC Erciyes University