Clinical trials: Cesarian Section
Pregnancy Related
Different Anesthesia Methods on Development of Postnatal Depression After Cesarean Delivery
Childbirth is one of the most painful experiences for a woman. Labor and period of pregnancy is associated with an increased risk of psychiatric disorders for a woman.
- Trial name
- NCT04565730
- Testing
- Grup I= General anesthesia group, Grup II= Spinal anesthesia group
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Medipol University
Caesarean Section, Pain, Acute
Subarachnoid Block With Ultrasound-Guided Transversalis Fascia Plane Block for Cesarean Section
Postoperative pain management is critical for the fulfillment of the maternal duties. The transversalis fascia plane (TFP) block provides adequate postoperative analgesia in the T12 and L1 dermatomes.
- Trial name
- NCT04172727
- Testing
- Bupivacaine Hcl 0.25% Inj, saline 0.9%
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Cesarean Section; Dehiscence
Predictors of Scar Dehiscence in Patients With Previous Caesarean Section
In recent decades, the percentage of Cesarean section deliveries has dramatically increased in most countries. Concomitantly, the rates of vaginal birth after Cesarean have decreased steadily.
- Trial name
- NCT03140683
- Testing
- non-stress test
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Assiut University
Pruritus Caused by Drug
Comparison of Pruritus Incidence After Intrathecal Morphine 0.1 vs 0.2 mg in Cesarean Section
This study compares the incidence of pruritus (itching) requiring treatment between two doses of intrathecal morphine (0.1 mg vs 0.2 mg) when used for spinal anesthesia during cesarean section.
- Trial name
- NCT07054775
- Testing
- Morphine Sulfate
- Where
- 2 sites in Thailand
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Povidone Iodine, Normal Saline
Povidone Iodine Versus Normal Saline in Preoperative Vaginal Cleansing Before Caesarean Section
Post-caesarean maternal infectious morbidity is still a big challenge despite prophylactic antibiotics and preoperative vaginal cleansing with povidone-iodine use in reduction of post-caesarean endometritis.Povidone iodine has…
- Conditions
- Povidone Iodine, Normal Saline, Pre-operative
- Trial name
- NCT06950229
- Testing
- Povidone-Iodine, Normal Saline
- Where
- Nigeria
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Federal Teaching Hospital Abakaliki
Uterine Scar
Assessment of Single and Double Layer Suturation of Lower Segment Uterine Incision by USG After C/S
After 6 months of cesarean delivery, the investigators will compare uterine incision scar defects of single and double layer suturation of uterine incision by transvaginal ultrasonography.
- Trial name
- NCT03676907
- Testing
- double layer suturation technique
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Gazi University
Postpartum Hemorrhage (Primary)
OBS-QoR-10 in Patients With and Without Postpartum Hemorrhage
Postpartum hemorrhage (PPH) remains a leading cause of maternal death and morbidity. Moreover, it also contributes to psychological trauma such as depression and post-traumatic stress disorder.
- Trial name
- NCT07199803
- Testing
- Obstetric Quality of Recovery-10 (ObsQoR-10©) Scoring Tool
- Where
- Canada
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Phenylephrine, Cesarean Birth
Comparison of Two Different Doses of Phenylephrine on Oxytocin Hemodynamic Effect
Cesarean section is one of the commonly performed surgical procedures in the world. Once baby is delivered during the surgical procedure anesthesiologist administer Oxytocin drug through IV cannula which helps the Uterus to…
- Trial name
- NCT07420127
- Testing
- Phenylephrine bolus 75 micrograms, Phenylephrine bolus 50 micrograms
- Where
- Pakistan
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Fertility
Fertility Post Placenta Accrete
This study is the first to investigate the fertility outcome and the influence on ovarian reserve after using uterine artery embolization during cesarean delivery.
- Trial name
- CSAC (NCT02821702)
- Testing
- Vaginal ultrasound, Blood sample
- Where
- Israel
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension
Ephedrine vs. Nor Epinephrine Infusion in Preventing Hypotension After Spinal Anesthesia for Cesarean Section
The purpose of the study is to determine if norepinephrine is more effective as a continuous intravenous (IV) infusion compared to continuous IV ephedrine associated with crystalloid loading for maintaining blood pressure during…
- Conditions
- Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension, Complications; Cesarean Section
- Trial name
- NCT02477501
- Testing
- Norepinephrine, Ephedrine
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Cesarean Scar Niche, Cesarean Wound; Dehiscence
Cesarean Scar Characteristics After Scheduled and Emergency Cesarean Deliveries
This study was designed to evaluate the scar characteristics following scheduled and emergency cesarean deliveries.
- Conditions
- Cesarean Scar Niche, Cesarean Wound; Dehiscence, Cesarean Section; Dehiscence
- Trial name
- NCT03609281
- Testing
- Ultrasound assessement of uterine scar
- Where
- Egypt
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Tanta University
Cesarean Section
Role of Prophylactic Antiemetics in Women Receiving Intrathecal Morphine and Lipophilic Opioids Added to Bupivacaine for Cesarean Section
Because the majority of Caesarean deliveries are performed under neuraxial anaesthesia, Intrathecal morphine has become the gold standard for post-Caesarean delivery analgesia.
- Trial name
- NCT06704139
- Testing
- Morphine - .25 mg, fentanyl + morphine, Ondansetron + Dexamethasone
- Volunteers
- 100 people
- Sponsor
- Assiut University
Adverse Effect
90% Effective Dose of Norepinephrine Infusions Under Intensive and Standard Treatment
The objective of this study is to investigate the 90% effective dose of norepinephrine infusions for preventing postspinal anesthesia hypotension under intensive and standard treatment during cesarean section
- Trial name
- NCT06151509
- Testing
- Alpha-Agonist, α-adrenergic receptor agonist
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University
Anaesthesia, Spinal
Pain Control and Side Effects in Cesarean Section Anesthesia: Comparison of Intrathecal Morphine and Fentanyl
Intrathecal opioids are frequently combined with local anesthetics to optimize spinal anesthesia for cesarean delivery. Fentanyl, a lipophilic opioid, offers rapid onset and enhanced intraoperative analgesia.
- Trial name
- FvMinSACS (NCT07144410)
- Testing
- fentanyl + morphine, fentanyl
- Where
- Romania
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Oradea
Pregnancy, Cesarean Section
Different Approaches to Maternal Hypotension During Cesarean Section
The aim of this study is to compare two different therapeutic approaches to blood pressure reduction: pharmacological vs. non-pharmacological.
- Conditions
- Pregnancy, Cesarean Section, Anesthesia,Spinal, Hypotension
- Trial name
- NCT00991627
- Testing
- Bupivacaine, Morphine, Lactated Ringer's solution
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University of Parma
Acute Pain
Influence of the Communication Between Nursing Staff and Patients on the Analgesic Response Following Caesarean Section
Effective management of postoperative pain is a priority for women undergoing cesarean delivery. Despite availability of modern analgesics, postoperative pain management remains a challenge.
- Trial name
- NCT05970029
- Testing
- Communication style
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- University of Haifa
Caesarean Section, Mother-Child Relations
Effect of Mother's Push at Cesarean Delivery Mother's PUSHING AT CS A RANDOMIZED CONTROLLED TRIAL
The purpose of this study is to assess the safety and efficacy of the mother's active pushing during cesarean delivery.
- Conditions
- Caesarean Section, Mother-Child Relations, Post Operative Pain, Postpartum Depression
- Trial name
- NCT05520580
- Testing
- Mother's push during CS
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Hypotension, Pregnancy Related
Non-invasive Haemodynamic Monitoring to Predict Spinal Hypotension During Caesarian Section
Spinal anaesthesia for elective caesarean section is associated with maternal hypotension, secondary to alteration of sympathetic tone and hypovolemia, in up to 70% of cases.
- Conditions
- Hypotension, Pregnancy Related, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
- Trial name
- NCT04608227
- Testing
- Clearsight monitoring
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospital Nord
Caesarean Section
The Pleth Variability Index and Hypotension at Caesarean Under Spinal.
During a caesarean section the blood pressure is usually measured every few minutes and it may fall too quickly to be detected in a timely fashion by this intermittent means.
- Trial name
- NCT02285569
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Pregnancy
Fetal Copeptin After Oxytocin Challenge Test
The relationship of uterine contractions on fetal copeptin levels in umbilical cord blood is studied.
- Trial name
- CopOCT (NCT01962701)
- Where
- Switzerland
- Volunteers
- 140 people
- Sponsor
- University of Zurich
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