Clinical trials: Cesarian Section
PONV
Granisetron vs Granisetron and Dexamethasone on the Reduction of Postoperative Nausea and Vomiting
Intrathecal morphine (ITM) has proven to be excellent in reducing postoperative pain. However, its use has commonly been associated with the occurrence of postoperative nausea and vomiting (PONV).
- Trial name
- NCT04570592
- Testing
- Granisetron 1 Mg/mL Intravenous Solution And Dexamethasone 4mg, Granisetron 1 Mg/mL Intravenous Solution
- Where
- Malaysia
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Spinal Hypotension
Ephedrine and Phenylephrine for Spinal Hypotension
Spinal anesthesia is widely used as the procedure of choice for cesarean delivery. In comparison to epidural anesthesia it is faster, easier to perform, patients are more comfortable, complication rates are lower, and it is more…
- Trial name
- NCT03047109
- Testing
- Phenylephrine, Ephedrine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Chronic Pain
The Chronic Pain Incidence After Elective and Urgent Cesarean Sections
The purpose of this study is to determine the effects of whether urgent or elective cesarean section on the occurrance of chronic pain.
- Trial name
- NCT02656264
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Tokat Gaziosmanpasa University
Anesthesia, Pregnancy, High Risk
Anesthetic Considerations for Repeat Cesarean Section - a Prospective Study
The purpose of this study is to examine the anesthetic considerations and outcomes during repeated caesarean section and to compare such considerations in low-order vs high-order repeated caesarean sections.
- Conditions
- Anesthesia, Pregnancy, High Risk, Pregnancy Related
- Trial name
- NCT04693572
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Adverse Effect
Norepinephrine Prophylaxis for Postspinal Anesthesia Hypotension in Parturients With Preeclampsia
The purpose of this study is to investigate the efficacy and safety of norepinephrine for prophylaxis against postspinal anesthesia hypotension in parturients with preeclampsia undergoing cesarean section.
- Trial name
- NCT04556357
- Testing
- Phenylephrine, Norepinephrine
- Where
- China
- Volunteers
- 138 people
- Sponsor
- General Hospital of Ningxia Medical University
Cesarean Section
Clinical Effect of Electroacupuncture on Postoperative Analgesia After Cesarean Sectionanalgesia After Cesarean Section
Cesarean section is one of the most common operations in obstetrics. A survey shows that the rate of cesarean section in China is more than 40%, and even more than 70%.
- Trial name
- NCT04879212
- Testing
- PCIA +Acupuncture group:
- Where
- China
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Caesarean Section, Obesity
Obesity Among Young Adult Males Born With Cesarean Section.
Previous research has suggested that cesarean section may be associated with an increased risk of developing obesity in childhood, adolescence and adulthood.
- Conditions
- Caesarean Section, Obesity, Cesarean Section Complications
- Trial name
- NCT03918044
- Where
- Sweden
- Volunteers
- 97,291 people
- Sponsor
- Karolinska Institutet
Postpartum Hemorrhage, Uterine Atony
Oxytocin Bolus Versus Infusion in High-Risk Patients Undergoing Elective Cesarean Section (INBOX-HR)
The goal of this randomized, double-blind clinical trial is to learn if Oxytocin is most effective at achieving adequate uterine tone (important for preventing postpartum hemorrhage) when administered as a bolus or an infusion in…
- Conditions
- Postpartum Hemorrhage, Uterine Atony, Uterine Atony With Hemorrhage, Elective Cesarean Section
- Trial name
- INBOX-HR (NCT07688512)
- Testing
- Oxytocin Bolus or Oxytocin Infusion
- Volunteers
- 180 people
- Sponsor
- Stony Brook University
Intestinal Microbiome
Cesarean Section and Intestinal Flora of the Newborn
Mode of delivery affects gut microbiome of the infant. Infants born by caesarean section have a less heterogenous microbiome for the first weeks of life.
- Trial name
- SECFLOR (NCT03568734)
- Testing
- Fecal transplant
- Where
- Finland
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Sture Andersson
Infection
Platelet Rich Plasma and Wound Healing After Cesarean Section
Objective: To assess the effect of autologous Platelet Rich Plasma (PRP) on wound healing and pain perception in high risk women undergoing cesarean sections in a low resource setting.
- Trial name
- NCT04669353
- Testing
- Platelet rich plasma
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Menoufia University
Glove Perforations, Needlestick Injuries
A Trial of Blunt Needles for the Reduction of Needlestick Injuries During Cesarean Section
The objective of this study was to determine if blunt needle use during cesarean section closure protects against glove perforation and percutaneous injury to the surgeon and surgical assistant.
- Trial name
- NCT00844636
- Testing
- Sharp needle, Blunt needles
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Uterine Niche, Closure; Incomplete, Uterus
Comparison the Effect of Uterine Closure Technique Difference on Uterine Niche After Caesarean Delivery.
Caesarean section scar may have result as isthmocele or scar detachment during pregnancy which is in few years after previous delivery.
- Trial name
- NCT04799457
- Testing
- Suture technique
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pain Postoperative, Caesarean Section; Pain
Supportive Analgesic Effect of Auricular Acupressure (AA) After Cesarean Section (CS)
Introduction: Severe acute pain after cesarean section is an independent risk factor for the development of chronic pain and increases the risk of postpartum depression threefold.
- Trial name
- AA-CS (NCT07322601)
- Testing
- Auricular Acupressure
- Where
- Vietnam
- Volunteers
- 70 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Cesarean Delivery Affecting Fetus or Newborn
Routine Maternal Leg Movements During the Second Stage and the Rate of Operative Deliveries
Cesarean delivery rates have risen in the US in a dramatic fashion from less than 5% in the 1960 to 32.7% by 2013 with stable rate around 32-33% in the last five years , cesarean delivery is associated with increased maternal…
- Trial name
- NCT03510130
- Testing
- Routine leg movement
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Spinal Anesthesia Evaluation, Cesarean Delivery
Dose-to-block Level Relation in Single Shot Spinal Anesthesia for Cesarean Section.
The study is designed to support or deny relation between the dose of hyperbaric bupivacaine given intrathecally and extent of spinal block level.
- Trial name
- SpinDoBlock (NCT06729567)
- Testing
- Spinal block level analysis, data collection
- Where
- Poland
- Volunteers
- 362 people
- Sponsor
- Centre of Postgraduate Medical Education
Postpartum Period, Depression
Relationship Between Postpartum Mood Disorders and Delivery Experience
The purpose of this study is to evaluate potential risk factors for developing postpartum depression or posttraumatic stress disorder during the first year postpartum in patients who have no preexisting history of PTSD or PPD.
- Conditions
- Postpartum Period, Depression, Stress Disorders, Post-Traumatic
- Trial name
- NCT03004872
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- University of Michigan
Adverse Anesthesia Outcome
Phenylephrine and Noradrenaline for Post Spinal Anesthesia Hypotension
Hypotension following spinal anesthesia for cesarean section is a serious problem. In this study we investigated the effect of the vasopressors phenylephrine and noradrenaline on postspinal hypotension.
- Trial name
- NCT03015857
- Testing
- phenylephrine, Norepinephrine, Bupivacaine
- Volunteers
- 200 people
- Sponsor
- Kasr El Aini Hospital
Cesarean Section, Postoperative Pain After Cesarean Section
Predictors of Severe Postoperative Pain Within 24 Hours After Elective Cesarean Delivery Under Spinal Anesthesia
This prospective observational study aims to identify predictors of severe postoperative pain during the first 24 hours after elective cesarean delivery under spinal anesthesia.
- Conditions
- Cesarean Section, Postoperative Pain After Cesarean Section, Acute Pain
- Trial name
- CS-PAIN24 (NCT07789301)
- Testing
- Observational Assessment of Postoperative Pain
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bursa City Hospital
Surgical Wound Infection
Vacuum Assisted Closure for Cesarean Section
To study if incisional vacuum-assisted closure can decrease the risk of infection in cesarean section incisions in the obese compared with standard sterile dressing.
- Trial name
- VACCS (NCT02390401)
- Testing
- Vacuum-assisted closure, Standard sterile dressing
- Where
- 4 sites in United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Anesthesia, Spinal, Cesarean Section
Post Spinal Anesthesia Hypotension and Preoperative Hydration
Study of the impact of preoperative oral rehydration on the incidence of spinal anesthesia-induced hypotension for scheduled cesarean section.
- Trial name
- NCT04450667
- Testing
- Nutricia PreOp
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brugmann University Hospital
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