Clinical trials: Cessation, Tobacco
Nicotine Dependence, Major Depressive Disorder
Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers
Persons who struggle with depression smoke at high rates and experience low quit rates in treatment. The best way to improve cessation treatment for this underserved population remains unknown.
- Trial name
- NCT02378714
- Testing
- Varenicline, BASC, Standard treatment
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Northwestern University
Nicotine Dependance, Serious Mental Illness
Evaluation of Community Health Worker Support to Help People With Serious Mental Illness to Quit Smoking
The purpose of this study is to learn whether providing additional smoking cessation support through specially trained members of behavioral healthcare team helps people quit smoking and improve their health.
- Conditions
- Nicotine Dependance, Serious Mental Illness, Smoking (Tobacco) Addiction, Tobacco Cessation
- Trial name
- NCT07789132
- Testing
- Integrated CHW Support intervention, Enhanced usual care (EUC)
- Where
- United States
- Volunteers
- 937 people
- Sponsor
- Massachusetts General Hospital
Quitting Smoking, Smoking Cessation
BREATHE 2 Clinic Stop-Smoking Treatment Outreach Study
The purpose of this research study is to see if offering adult primary care patients who smoke combustible cigarettes more frequent outreach, more choices about how they receive that outreach, and more smoking treatment options…
- Conditions
- Quitting Smoking, Smoking Cessation, Smoking, Cigarette
- Trial name
- NCT05683821
- Testing
- Text message smoking treatment, Nicotine replacement therapy sampling, Wisconsin Tobacco QuitLine Referral
- Where
- United States
- Volunteers
- 12,376 people
- Sponsor
- University of Wisconsin, Madison
Tobacco Cessation, Tobacco Abstinence
Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness
This study is investigating tobacco use and providing tobacco treatment among people experiencing homelessness in California, in San Francisco and Los Angeles.
- Conditions
- Tobacco Cessation, Tobacco Abstinence, Tobacco Use, Tobacco Use Cessation
- Trial name
- NCT07148232
- Testing
- Nicotine Replacement Therapy (NRT), Wellness Coaching
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, San Francisco
Tobacco Dependence
Single-dose Nicotine Pharmacokinetics With Three Oral Nicotine Replacement Products. A Study in Healthy Smokers.
Single-dose nicotine pharmacokinetics with three oral nicotine replacement products.
- Trial name
- NCT01234792
- Testing
- 6 mg Experimental nicotine gum, 4 mg Nicotine Gum/, 2 mg Nicotine Gum
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- McNeil AB
Cigarette Smoking, Tobacco Use
Gabapentin for Smoking Cessation
Gabapentin is an anti-epileptic agent that has shown preliminary evidence of efficacy for improving symptoms of cocaine and alcohol withdrawal in pilot studies.
- Trial name
- NCT00578552
- Testing
- Gabapentin - 1800 mg/day, Gabapentin - 2700 mg/day
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Nicotine Addiction
Comparative Effectiveness of Cystine Versus Nicotine Replacement Therapy
A pragmatic, single blinded, randomized, controlled non-inferiority trial of Cytisine versus Nicotine Replacement Therapy for continuous abstinence is conducted in the government run primary health hospitals in Mongolia.
- Trial name
- NCT04126135
- Testing
- Cytisine, Nicotine Replacement Therapy (NRT)
- Where
- Mongolia
- Volunteers
- 1,307 people
- Sponsor
- Loma Linda University
Nicotine Dependence, Cigarettes
Penn State TXT2STAYQUIT Study- a Texting Study to Help Hospitalized Smokers Stay Quit
This study aims to pilot a method of collecting the post-discharge follow-up data required by the Joint Commission Tobacco Measure Set, using text messages sent to and received from patients' cellular-telephones.
- Trial name
- NCT02986711
- Testing
- Motivational Text Messages, Control
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Bladder Cancer
Determinants of Bladder Cancer Recurrence Study (The DETER Study)
The purpose of this study is to learn how different lifestyle factors, such as cigarette smoking and body weight, change after a diagnosis of bladder cancer, and how they influence who gets a bladder cancer recurrence and who…
- Trial name
- NCT02400944
- Testing
- questionnaires, Saliva and/or urine sample
- Where
- 4 sites in United States
- Volunteers
- 600 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Smoking Cessation Counselling
Pragmatic Trial of Text Messages to Recruit Unassisted Tobacco Users Into Quitline Service
The goal of this pragmatic trial is to compare the effects of text messages on quitline enrollment by patients identified in electronic health records as unassisted tobacco users.
- Trial name
- NCT07102290
- Testing
- Free Help, Free Nicotine message, Spanish: Free help message
- Where
- United States
- Volunteers
- 4,171 people
- Sponsor
- University of California, Davis
Tobacco Use, Smoking Cessation
Chatbot Counselling for Smoking Cessation in Youths
The goal of this pilot trial is to develop and examine the trial feasibility and acceptability of a chatbot for smoking cessation in youth smokers. Specific aims include: 1.
- Trial name
- NCT06470776
- Testing
- Chatbot counselling, Peer counselling
- Where
- Hong Kong
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Smoking
Program on Lung Cancer Screening and Tobacco Cessation
In this sequential, multiple assignment, randomized trial (SMART) current smokers who are eligible for lung cancer screening will be identified using the electronic medical record at the University of Minnesota and Minneapolis VA…
- Trial name
- PLUTO (NCT02597491)
- Testing
- TLC monthly, TLC quarterly, MTM
- Volunteers
- 1,000 people
- Sponsor
- University of Minnesota
Tobacco Smoking in Schizophrenic Patients
Antismoking Effects of Electronic Cigarettes in Subjects With Schizophrenia and Their Potential Influence on Cognitive Functioning.
It is well established in studies across several countries that tobacco smoking is more prevalent among schizophrenic patients than the general population.
- Trial name
- SCARIS (NCT01979796)
- Testing
- Ecig 24 mg nicotine, Ecig 0 mg nicotine, Nicotine free inhalator
- Sponsor
- University of Catania
Nicotine Dependence, Psychotic Disorders
Contingency Management for Smoking Cessation Among Veterans With Psychotic Disorders
This study examines the use of contingent incentives to increase attendance at smoking cessation treatment sessions by smokers with schizophrenia and other psychoses who want to quit smoking.
- Trial name
- NCT00508560
- Testing
- Contingency Management, Reward
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- US Department of Veterans Affairs
Tobacco Use, Tobacco Use Cessation
Automating Tobacco Cessation in Primary Care
This study focuses on improving how primary care teams identify patients who smoke and offer access to nicotine replacement therapy, or NRT.
- Trial name
- NCT07735286
- Testing
- Tobacco counseling resources
- Where
- United States
- Volunteers
- 4,800 people
- Sponsor
- University of Pennsylvania
Smoking Reduction, Smoking Cessation
Development and Assessment of a Teacher-led Intervention in Preventing Tobacco Use Among the Youth in Ghana
The main purpose of this experimental study is to compare the existing health education program for School Health and Education Program (SHEP) in the Junior High Schools with a new health education model (Smart-Kids') for the…
- Conditions
- Smoking Reduction, Smoking Cessation, Smoking, Tobacco, Smoking Behaviors
- Trial name
- NCT04891939
- Testing
- Health education lessons (Smart-Kid's program), School Health and Education Program (SHEP)
- Volunteers
- 2,314 people, healthy volunteers welcome
- Sponsor
- Ghana Health Services
Tobacco Use
Strategies to Help Adult ED Patients Quit Smoking
The purpose of this study is to determine whether a brief, focused intervention in the hospital emergency department is effective in helping adults quit smoking.
- Trial name
- NCT00297466
- Testing
- transdermal nicotine patches, Motivational interview
- Where
- United States
- Volunteers
- 336 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking, Smoking Cessation
Identifying Optimal Smoking Cessation Intervention Components (Cessation)
The goal of this research is to identify the best smoking cessation intervention components to be combined into a state-on-the-art, comprehensive smoking cessation intervention.
- Conditions
- Smoking, Smoking Cessation, Nicotine Dependence
- Trial name
- Cessation (NCT01116986)
- Testing
- Counseling before quit attempt, Minimal In-person counseling during quit attempt, Intensive in-person counseling during the quit attempt
- Where
- United States
- Volunteers
- 637 people
- Sponsor
- University of Wisconsin, Madison
Tobacco Use Disorder
Non-Nicotine Agents for Smoking Cessation
The primary objective of this study is to determine which is the better approach to smoking cessation in veterans: bupropion combined with transdermal nicotine or high dose nicotine replacement therapy (NRT) using transdermal…
- Trial name
- NCT00108537
- Testing
- bupropion and transdermal patch, transdermal patch and nicotine inhaler
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Nicotine Dependence
Study of Varenicline (Champix) for Smoking Cessation/Reduction in Patients With Bipolar Disorder
Bipolar Disorder is a chronic relapsing mental disorder characterized by periods of elevated, expansive and irritable mood, often alternating with periods of significant clinical depression.
- Trial name
- NCT01093937
- Testing
- varenicline
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre for Addiction and Mental Health
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