Clinical trials: Cessation, Tobacco
Smoking, Cigarette, Smoking Cessation
Health Systems Reach Interventions Project
This project seeks to identify ways to enhance the reach of evidence-based smoking cessation treatments among adult primary care patients who smoke daily and are not ready to start treatment at study enrollment.
- Trial name
- NCT04199117
- Testing
- Varenicline, Combination nicotine patch and nicotine mini-lozenge treatment, Monetary incentives for initiating treatment
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- University of Wisconsin, Madison
Cigarette Smoking, Smoking Cessation
Contingency Management, Quitting Smoking, and ADHD
The overall goal of the study is to evaluate how motivation and readiness for change are influenced in the context of a smoking cessation attempt. A total of 60 adult (i.e.
- Trial name
- ADQUIT (NCT02266784)
- Testing
- Contingency Management (CM), Transdermal nicotine skin patches (i.e. Habitrol), Supportive Counseling
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Duke University
Tobacco Use Disorder
Study of EMB-001 as a Potential Smoking Cessation Treatment
EMB-001 is a combination of 2 drugs: the cortisol synthesis inhibitor, metyrapone (Metopirone®), and the benzodiazepine receptor agonist, oxazepam (original trade name Serax®; now marketed as oxazepam (generic) only).
- Trial name
- NCT04933916
- Testing
- EMB-001
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Embera NeuroTherapeutics, Inc.
Tobacco Use Cessation, Smoking Cessation
Implementation of HIT-Enhanced Tobacco Treatment for Hospitalized Smokers
This study will implement and test the effectiveness and cost-effectiveness of a tobacco cessation intervention (Academic Detailing + Integrated Tobacco Order Set - AD + ITOS) for adults admitted to the hospital.
- Conditions
- Tobacco Use Cessation, Smoking Cessation, Smoking, Tobacco Use Disorder
- Trial name
- NCT01691105
- Testing
- AD + Integrated Tobacco Order Set
- Where
- United States
- Volunteers
- 1,044 people
- Sponsor
- Yale University
Tobacco Use Disorder
Effect of a Non-Invasive Brain Stimulation Technique on Smoking Cessation Behaviors
In this pilot study, the feasibility of using tDCS (a non-invasive brain stimulation technique) while performing a task requiring cognitive flexibility will be examined in smokers and initial data will be collected regarding the…
- Trial name
- NCT03386253
- Testing
- active tDCS
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tobacco Dependence
Web Assisted Tobacco Intervention With Community Colleges
This trial will test the effectiveness of an enhanced web-based smoking cessation intervention for student smokers at 2-year Community Colleges.
- Trial name
- WATI (NCT01692730)
- Testing
- Enhanced Web Assisted Tobacco Intervention, Basic Web Assisted Tobacco Intervention
- Where
- United States
- Volunteers
- 1,452 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Nicotine Dependence
Approach Bias Retraining to Augment Smoking Cessation
Tobacco use is the most preventable cause of disease, disability, and death in the United States. Standard smoking cessation care (cognitive behavioral therapy and nicotine replacement therapy), is effective in approximately 20%…
- Trial name
- NCT03325777
- Testing
- Approach Bias Retraining
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Jasper A. Smits
Nicotine Dependence, Smoking
Varenicline for Smoking Cessation in Heavy Drinking Smokers
The purpose of this study is to determine whether extended pretreatment with varenicline (Chantix) is more efficacious for smoking cessation than standard pretreatment, how well varenicline is tolerated in heavy drinking smokers…
- Conditions
- Nicotine Dependence, Smoking, Heavy Drinking
- Trial name
- NCT00860028
- Testing
- Extended Varenicline Pretreatment, Short-term Varenicline Pretreatment
- Volunteers
- 30 people
- Sponsor
- Yale University
Tobacco Use Cessation, Cancer Prevention
Project Impact 2: A Culturally Tailored Smoking Cessation Intervention for Latino Smokers
The goal of this research study is to learn how 3 different kinds of counseling treatments may help individuals to quit smoking.
- Trial name
- NCT02596711
- Testing
- Nicotine Patch, Questionnaires, Carbon Monoxide (CO) Test
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cardiovascular Diseases, Diabetes Mellitus, Type 2
Evaluating a Web-Based Cardiovascular Disease Risk Factor Reduction Program Among American Indians
Cardiovascular disease (CVD) is a serious health concern for American Indians, but there have been few behaviorally based programs to lessen CVD risk among this population.
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Type 2, Hypertension, Obesity
- Trial name
- NCT00608387
- Testing
- Chronic disease management Web-based software
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Black Hills Center for American Indian Health
Tobacco Use, Cigarette Smoking
RTMS Targets Neural Circuits for Smoking Cessation
Cigarette smoking is a significant public health concern. Transcranial magnetic stimulation (TMS) is a non-invasive form of brain stimulation that has already displayed remarkable potential for producing novel…
- Trial name
- NCT04903028
- Testing
- Active rTMS 10 Hz DLPFC
- Where
- 2 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Tobacco Smoking
Heart Rate Variability Biofeedback for Smoking Cessation
Open trial of heart rate variability biofeedback as an adjunct to individualized smoking cessation counseling (SCT) plus transdermal nicotine replacement patch (NRT) in smokers with elevated emotional distress.
- Trial name
- HRVB-SCT (NCT03972137)
- Testing
- Cognitive-Behavioral Smoking Cessation, Heart Rate Variability Biofeedback (HRVB), Transdermal Nicotine patch
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Tobacco Use, Smoking Cessation
A Guided Imagery Tobacco Cessation Intervention Delivered by a Quit Line and Website
Tobacco use is still the leading cause of preventable disease and death in the United States. Tobacco quit lines are effective at helping smokers to quit, but quit lines are underutilized, especially by men and racial/ethnic…
- Conditions
- Tobacco Use, Smoking Cessation, Smoking, Tobacco, Tobacco Smoking
- Trial name
- QLImagery (NCT02968381)
- Testing
- Imagery Intervention, Control Condition
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Arizona
E Cigarette Use, Cessation, Tobacco
Evaluation of Dependence and Nicotine Replacement Therapy-Supported Cessation Efforts Among Regular Electronic Cigarette Use
This study aims to improve understanding of how people who use electronic cigarettes (ECIGs or e-cigarettes) respond when they try to stop using them and whether nicotine replacement therapy (NRT) can make that process easier.
- Conditions
- E Cigarette Use, Cessation, Tobacco, Cessation, Nicotine
- Trial name
- NCT07786896
- Testing
- Nicotine Replacement Therapies, Brief Behavioral Counseling
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- West Virginia University
Smoking
Smoking Cessation in Workplaces in Hong Kong [Phase II]
This study has the following objectives: 1. To examine the employers'/managerial staff's knowledge, attitudes and practices in promoting smoking cessation in workplace. 2.
- Trial name
- NCT02659774
- Testing
- workshop (Motivational intervention), Health talk, Face to Face counseling
- Where
- China
- Volunteers
- 600 people
- Sponsor
- The University of Hong Kong
Smoking Cessation
Combining Default Choices and a Decision Aid to Improve Tobacco Cessation
The FIRST cluster randomized trial will evaluate the effect of 1) a training program encouraging general practitioners to offer smoking cessation treatment as a default choice to all current smokers consulting a general…
- Trial name
- FIRST (NCT04868474)
- Testing
- Training program and decision aid, Refresher course
- Where
- 2 sites in France, Switzerland
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Tobacco Use Cessation
Mi QUIT CARE (Mile Square QUIT Community-Access-Referral-Expansion)
The over-arching research question is: Does message (Advise) and referral approach (Refer) influence a patient's willingness to "opt-in" to receive a call from an Illinois Tobacco Quitline (ITQL) smoking cessation coach in…
- Trial name
- NCT04827420
- Testing
- Mi Quit Care
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Smoking Cessation
Behavioral and Enhanced Perinatal Intervention for Cessation (B-EPIC): Reducing Tobacco Use Among Opioid Addicted Women
This study tests an intervention for tobacco cessation (named B-EPIC) in an established community medication assisted treatment (MAT) clinic for pregnant and postpartum women with opioid dependence.
- Trial name
- B-EPIC (NCT03796208)
- Testing
- Behavioral and Enhanced Perinatal Intervention for Cessation (B-EPIC), Treatment As Usual
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- Kristin Ashford
Tobacco Cessation, Asthma COPD
The Effect of Immediate Smoking Cessation Interventions for Smokers With Chronic Airway Diseases
Smoking cessation support is provided by smoking cessation outpatient clinics in our country. Smokers with chronic airway diseases can also apply to these services by making an appointment from quit lines.
- Conditions
- Tobacco Cessation, Asthma COPD, Bronchiectasis Adult
- Trial name
- NCT05764343
- Testing
- Immediate smoking cessation support
- Where
- Turkey (Türkiye)
- Volunteers
- 397 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Nicotine Addiction, Smoking Cessation
Extinction Updating in Reconsolidation
Smoking occurs in approximately 21% of the US population, is responsible for an annual mortality rate of approximately 438,000 citizens, and has an associated healthcare economic burden of $167 billion.
- Trial name
- NCT02154685
- Testing
- Retrieval-Extinction, Non-Retrieval Extinction
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
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