Clinical trials: Cessation of Smoking
Lung Cancer, Precancerous Condition
Green Tea Extract in Treating Current or Former Smokers With Bronchial Dysplasia
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming. The use of Polyphenon E, a substance found in green tea, may keep cancer from forming in current or former smokers with bronchial dysplasia.
- Conditions
- Lung Cancer, Precancerous Condition, Tobacco Use Disorder
- Trial name
- NCT00611650
- Testing
- defined green tea catechin extract
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- British Columbia Cancer Agency
Smoking Cessation
Countering Young Adult Tobacco Marketing in Bars
The goal of the study is to implement and evaluate interventions to decrease smoking among young adults attending bars and nightclubs.
- Trial name
- NCT01686178
- Testing
- Anti-smoking social marketing campaign
- Where
- United States
- Volunteers
- 17,422 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking Cessation
Efficacy of Centanafadine SR as a Potential Smoking Cessation Treatment
This study will explore the efficacy and tolerability of centanafadine at a dose of 400 mg per day of centanafadine in promoting smoking abstinence in adult smokers seeking to quit.
- Trial name
- NCT05066724
- Testing
- Centanafadine
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Cancer, Smoking
Smoking Cessation Smartphone App for Cancer Patients (Quit2Heal Study)
The goal of this study is to determine whether the novel smartphone application designed specifically for cancer patients to quit smoking (Quit2Heal) provides higher quit rates than the current standard smoking cessation app.
- Trial name
- Quit2Heal (NCT03600038)
- Testing
- Experimental smoking cessation smartphone app, Standard of care smoking cessation smartphone app
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Fred Hutchinson Cancer Center
Smoking Cessation
Cumulative Skin Irritation Potential of a New 25 mg Nicotine Patch
An investigation on the cumulative skin irritation potential of a newly developed 25 mg nicotine patch. Evaluation of skin irritation of a newly developed 25 mg nicotine transdermal patch
- Trial name
- NCT00967174
- Testing
- Nicotine Patch, SLS Comparator Patch
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- McNeil AB
Smoking Cessation
Rural COPD E-Visit Study
The purpose of this study is to evaluate an electronic visit (e-visit) for COPD screening and for quitting smoking. Participants will be randomly assigned to receive either the smoking cessation e-visit or not.
- Trial name
- NCT06236347
- Testing
- Smoking cessation e-visit, Treatment as usual
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Smoking Cessation
Evaluation Study on Smoke-free Teens Programme 2020-2021
The objectives are: i. To evaluate Smoke-free Teens' change in knowledge on smoking hazards, attitudes towards smoking, tobacco control and smoking cessation, and practices for promoting smoking prevention and cessation, ii.
- Trial name
- NCT04599049
- Testing
- six sessions of online classes and virtual training day camps through Zoom in two days
- Where
- Hong Kong
- Volunteers
- 173 people
- Sponsor
- The University of Hong Kong
Smoking Cessation, Smoking, Cigarette
Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia
The goal of this clinical trial is to evaluate the effectiveness and implementation of a pharmacist-delivered MTM (medication therapy management) approach, called QuitAid, to quitting cigarette smoking in rural Appalachia.
- Conditions
- Smoking Cessation, Smoking, Cigarette, Smoking Reduction, Smoking
- Trial name
- NCT05660525
- Testing
- 4 weeks of Nicotine lozenge, 8 weeks of Nicotine Replacement Therapy Patch, QuitAid
- Where
- United States
- Volunteers
- 768 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Smoking, Smoking Cessation
BRP1802 Smoking Abstinence Study
A single-center study designed to evaluate changes in short-term biomarkers of potential harm (BoPH) in healthy adult cigarette smokers of two age groups (Group A: 24-34 years; Group B: 35-60 years) during 14 days of smoking…
- Conditions
- Smoking, Smoking Cessation, Tobacco Use
- Trial name
- NCT04979013
- Testing
- Smoking Abstinence
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Tobacco Use Cessation
Mi QUIT CARE (Mile Square QUIT Community-Access-Referral-Expansion)
The over-arching research question is: Does message (Advise) and referral approach (Refer) influence a patient's willingness to "opt-in" to receive a call from an Illinois Tobacco Quitline (ITQL) smoking cessation coach in…
- Trial name
- NCT04827420
- Testing
- Mi Quit Care
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Smoking Cessation, Smoking, Tobacco
Path2Quit Tobacco Intervention For African Americans
The purpose of this research is to study a smoking cessation program for adult smokers in Northeast Ohio. The study will also look at how different people respond to the program.
- Trial name
- NCT03524482
- Testing
- SmokeFreeText, Path2Quit
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Chronic Obstructive Pulmonary Disease
Endotoxin and Inflammatory Markers in Healthy Non-Smokers and Current Smokers Including Patients With Chronic Obstructive Pulmonary Disease (COPD)
The primary aim of this study is to investigate the effects of inhaled lipopolysaccharide endotoxin (LPS) on bronchial and alveolar exhaled nitric oxide (NO) and NO metabolites and other inflammatory markers and mediators in…
- Trial name
- NCT00159289
- Testing
- Inhalation of LPS
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London
Smoking Cessation
Post-Discharge Smoking Cessation Strategies: Helping HAND 4
This randomized controlled trial will compare the effectiveness of two models of post-discharge tobacco cessation treatment for adult smokers admitted to 3 U.S. hospitals.
- Trial name
- HH4 (NCT03603496)
- Testing
- Transitional Tobacco Care Management (TTCM), eReferral to State Tobacco Quitline (QL), Nicotine replacement therapy
- Where
- 3 sites in United States
- Volunteers
- 1,416 people
- Sponsor
- Massachusetts General Hospital
Smoking, Motivational Interviewing
The Effect of Motivational Interviewing Technique on Smoking Urge and Smoking Cessation Success in Teachers
Background: Smoking, which remains one of the biggest public health threats that the world faces and has reached epidemic proportions, continues to cause more than eight million deaths on average per year worldwide.
- Conditions
- Smoking, Motivational Interviewing, School Health, Nursing
- Trial name
- NCT05374707
- Testing
- MOTIVATIONAL INTERVIEWING
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Smoking Cessation, Smokeless Tobacco
In-vivo Extraction of Pb, Cd and TSNA From Swedish Snus
In an open label, randomized, two-way cross-over study, 32 male healthy regular snus users will be given repeated doses of four different types of portion snus: "General", "Catch", "Catch Mini" and "Catch Dry Mini".
- Conditions
- Smoking Cessation, Smokeless Tobacco, Harm Reduction
- Trial name
- SMWS03 (NCT01369693)
- Testing
- Buccal administration of nicotine
- Where
- Sweden
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Contract Research Organization el AB
Smoking Cessation
Safety and Pharmacodynamics of SEL-068 Vaccine in Smokers and Non-Smokers
The purpose of this study is to evaluate the safety and pharmacodynamics of SEL-068. Increasing subcutaneous doses of SEL-068 will be administered to healthy non-smoker and smoker volunteers.
- Trial name
- NCT01478893
- Testing
- SEL-068, Saline
- Where
- Belgium
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Selecta Biosciences, Inc.
Smoking Cessation
Implementing Tobacco Treatment in Low Dose CT Lung Cancer Screening Sites
This study is to help determine the most effective type or combination of treatments to offer patients seeking lung cancer screening who are smokers to help them reduce the number of cigarettes they smoke, or quit smoking.
- Trial name
- NCT03315910
- Testing
- Motivational Interviewing (MI), Nicotine Replacement Therapy (NRT), Nicotine Lozenge
- Where
- 18 sites in United States
- Volunteers
- 807 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Smoking Cessation
Optimal TTM Tailoring for Population Cessation
This study explored optimal tailoring strategies for population tobacco cessation in 4 treatment groups and a control group over 24 months.
- Trial name
- STAR (NCT01544010)
- Testing
- Stage-Tailored Manual, Stage Tailored Feedback Report, Moderate TTM-Tailored Feedback Report
- Where
- United States
- Volunteers
- 3,006 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Smoking Cessation
The Effectiveness of Using E-Cigarettes for Smoking Cessation and Decreasing Risk of Diseases Among Heavy Smokers
The goal of this clinical trial is to evaluate effectiveness of using e-cigarettes as harm reduction strategy for smoking cessation and decreasing risk of diseases in heavy smokers.
- Trial name
- NCT05639790
- Testing
- Electronic cigarettes + Health Counselling, Health Counselling
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shenzhen Smoore Technology Limited
Acute Coronary Syndrome, Tobacco Use
Integrated Smoking Cessation and Mood Management for ACS Patients
Quitting smoking following acute coronary syndrome can reduce mortality up to 50%. However, depression and smoking are highly co-morbid and depressed mood may interfere with cessation and independently predicts mortality.
- Trial name
- PACES (NCT03029923)
- Testing
- Experimental: Behavioral Activation Treatment for Cardiac Smokers (BAT-CS), Smoking cessation plus Health and Wellness
- Where
- United States
- Sponsor
- The Miriam Hospital