Clinical trials: Change; Mental
Altered Mental Status
Diagnostic Yield and Influence on Length of Stay of Brain Computed Tomography for Elderly Patients With Altered Mental Status in an Emergency Setting
The confusional syndrome is defined by the acute or subacute onset of a deficit syndrome (temporo-spatial disorientation, memory and concentration disorders, abnormal behavior, impairment of intellectual efficiency, fluctuation…
- Trial name
- DISCUSS-CT (NCT04929704)
- Where
- France
- Volunteers
- 470 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Trauma and Stressor Related Disorders, Post Traumatic Stress Disorder
Comparing Standard vs. Modified Reconsolidation Blockade for the Treatment of Psychological Trauma
The investigators propose to examine a mismatch-based method of reconsolidation blockade for the treatment of psychological trauma in military personnel and Federal police officers.
- Conditions
- Trauma and Stressor Related Disorders, Post Traumatic Stress Disorder, Acute Stress Disorder, Adjustment Disorders
- Trial name
- NCT04982211
- Testing
- Propranolol
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Douglas Mental Health University Institute
Psychological Aspects, Skin Temperature Change
Enhancing Autonomic Regulation and Attention Through Biofeedback in Female Athletes
This study aimed to evaluate the impact of a multimodal biofeedback intervention on autonomic function and sustained attention in female volleyball players.
- Conditions
- Psychological Aspects, Skin Temperature Change, Biofeedback Training, Volleyball Players
- Trial name
- NCT07061834
- Testing
- Biofeedback training, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Personality Disorders, Borderline Personality Disorder
Evaluation of AIT Study
Specialized treatment of personality disorders (PD) in youth has been neglected for a long time, because these disorders were not diagnosed before the age of 18.
- Trial name
- NCT02518906
- Testing
- Adolescent Identity Treatment, DBT-A
- Where
- 3 sites in Chile, Germany and 1 more
- Volunteers
- 60 people
- Sponsor
- Klaus Schmeck
Patellar Tendinopathy
Unlocking the Hidden Effects of Shockwave: Longitudinal Changes in Sensorimotor Function and Kinesiophobia in Adolescents With Patellar Tendinopathy
Patellar tendinopathy (PT) is a commonly used term for the clinical manifestation of patellar tendon pain and functional limitation with multifactorial etiology.
- Trial name
- NCT07797764
- Testing
- Extracorporeal Shockwave Therapy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ahmed Alshimy
Major Depressive Disorder
The Relationship Among Changes in Brain Network Activation in Adult Outpatients With Major Depressive Disorder
The purpose of this study is to explore patterns of Brain Network Activation (BNA) changes from baseline to endpoint on 1) efficacy of core symptoms of Major Depressive Disorder (MDD) and 2) improvement of cognitive dysfunction…
- Trial name
- NCT02749721
- Testing
- vortioxetine
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Rush University Medical Center
Spondylarthritis, Spondylarthropathies; Spondylitis, Ankylosing
Effects of a Digital Exercise Intervention on Sleep and Physical Activity in Patients With Spondyloarthritis
The goal of this clinical trial is to assess whether a tailored digital Adapted Physical Activity (APA) program can improve physical activity levels and sleep quality in adults diagnosed with spondyloarthritis (SpA).
- Trial name
- ASPIRE (NCT07034404)
- Testing
- Digital Adapted Physical Activity, Control (Standard treatment)
- Where
- 3 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Grenoble
Neurocognitive Disorders
Adapted Physical Activity Education in Patients With Neurocognitive Disorder
This study aims to compare the effect of a program of Adapted Physical Activity (APA) versus the same program combined with a physical activity education program (PAE).
- Trial name
- EduAPA (NCT05866822)
- Testing
- APA, PAE
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Subjective Cognitive Decline (SCD), Olfactory Dysfunction
The Efficacy of Modified Olfactory Training for MCI High-Risk Individuals
The goal of this clinical trial is to validate the effectiveness of the modified olfactory training device, the main questions it aims to answer are: Is it possible that the device can delay the progression of MCI in older…
- Conditions
- Subjective Cognitive Decline (SCD), Olfactory Dysfunction, Mild Cognitive Impairment (MCI), ELDERLY PEOPLE
- Trial name
- NCT06821828
- Testing
- Modified olfactory training device, Conventional olfactory training device
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Peking University Third Hospital
Bipolar Depression
Riluzole in the Treatment of Bipolar Depression
Bipolar disorder is a common and often chronic and debilitating mental illness. The depressive phase of bipolar disorder contributes the largest portion of the disorder, and treatment resistant bipolar depression represents a…
- Trial name
- NCT00544544
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Mclean Hospital
Episiotomy, Anxiety
The Effect of the Modified Simulation Model on Self-Efficacy, Anxiety, and Academic Motivation in Episiotomy Training
It was planned as a randomized controlled study to determine the effect of the modified simulation model on self-efficacy, anxiety and academic motivation in episiotomy training.
- Conditions
- Episiotomy, Anxiety, Simulation
- Trial name
- Episiotomy (NCT06415877)
- Testing
- Episio Training
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Emine Yıldırım
Anorexia Nervosa, Autism Spectrum Disorder
TRANPAS - TReating Anorexia Nervosa Plus Autism Spectrum
In a pilot study, the investigators will validate a so-called autism care location in an inpatient ward. The care location will be adapted for patients with anorexia nervosa (AN) and concurrent autism (AN+autism).
- Trial name
- TRANPAS (NCT06368687)
- Testing
- Anorexia nervosa plus autism
- Volunteers
- 10 people
- Sponsor
- Göteborg University
Alzheimer's Disease, Dementia
Reducing Disabilities in Alzheimer's Disease (RDAD) Translation in Area Agencies on Aging (AAAs)
The University of Washington's Northwest Research Group on Aging is partnering with Area Agencies on Aging (AAA) in Washington and Oregon to complete this translational investigation of RDAD (Reducing Disabilities in Alzheimer's…
- Conditions
- Alzheimer's Disease, Dementia, Memory Impairment, Cognitive Impairment
- Trial name
- RDAD (NCT01708304)
- Testing
- RDAD
- Where
- United States
- Volunteers
- 510 people
- Sponsor
- University of Washington
Obsessive-Compulsive Disorder
Internet-delivered Attention Training for Obsessive-Compulsive Disorder
The goal of this study is to investigate an attention training program for participants with Obsessive-Compulsive Disorder. The attention training consists of a modified dot probe task with picture stimuli related to washing and…
- Trial name
- NCT02018848
- Testing
- Attention Training Program
- Where
- Germany
- Volunteers
- 108 people
- Sponsor
- Humboldt-Universität zu Berlin
Substance Use, Binge Drinking
Substance Use Screening to Encourage Behavior Change Among Young People in Primary Care
This study evaluates whether completing a short screening questionnaire about health behaviours in the waiting room before a primary care consultation decreases excessive substance use in young people aged 14 to 24 years.
- Conditions
- Substance Use, Binge Drinking, Cannabis Use, Adolescent Behavior
- Trial name
- YP-HEALTH (NCT04146714)
- Testing
- Substance use questionnaire, Physical activity questionnaire
- Where
- Switzerland
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Prof. Dagmar M. Haller
Social Anxiety Disorder, Interpretation Bias
Brief Interpretation Bias Modification for Social Anxiety Disorder in Pakistani Young Adults: An Experimental Evaluation
This randomized, single-blind trial tests whether one session of interpretation bias modification reduces immediate social-evaluative anxiety and shifts interpretation bias in Pakistani university students aged 18 to 25 years…
- Trial name
- BIBM-SAD-PYA (NCT07406321)
- Testing
- WSAP-based interpretation bias modification, WSAP interpretation control condition
- Where
- Pakistan
- Volunteers
- 130 people
- Sponsor
- Ather Mujitaba
Mental Health
Trial Phase: Syndemic Adapted Medly Uganda
The purpose of this study is to evaluate the effectiveness of the Syndemic-Adapted Medly Uganda (SAMU) in improving mental health care among adults living with HIV and hypertension in Uganda.
- Trial name
- SAMU (NCT07525271)
- Testing
- Syndemic-Adapted Medly Uganda (SAMU)
- Where
- 3 sites in Uganda
- Volunteers
- 1,500 people
- Sponsor
- Yale University
Depression, Postpartum, Anxiety
The Effect of the Close Collaboration With Parents Intervention - Estonian Study
The overall aim of the study is to implement an evidence-based intervention called 'Close Collaboration with Parents' in Estonian neonatal units.
- Trial name
- NCT06258655
- Testing
- Close Collaboration with Parents
- Where
- Finland
- Volunteers
- 622 people
- Sponsor
- University of Turku
Delirium on Emergence
Post Anesthesia Emergence and Behavioral Changes in Children Undergoing MRI
Children who receive general anesthesia may become agitated (emergence delirium) in the recovery period. This occurs more often after inhalational anesthetics, particularly sevoflurane and desflurane than after propofol.
- Trial name
- NCT02111447
- Testing
- Propofol, Sevoflurane, Isoflurane
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- State University of New York at Buffalo
PTSD, Depression
Increasing Psychological Resilience in Combat Soldiers Applying Advanced Eye-Tracking-Based Attention Bias Modification
Military service in combat units entails exposure to traumatic events that require mental adjustment. To develop and efficiently apply attention bias modification interventions aimed at enhancing soldiers' mental resilience, it…
- Conditions
- PTSD, Depression, Anxiety Disorders
- Trial name
- NCT05294848
- Testing
- Gaze-Contingent Feedback Training, Attention Bias Modification, Neutral Control
- Where
- Israel
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
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