Clinical trials: Change; Mental
Cognitive Impairment
Brain Functional Changes Accompany Modulatory Effects of Transcranial Direct Current Stimulation in Cognitive Impairment
The goal of this observational study was to examine the brain functional alterations accompanying cognitive modulatory effect of anodal transcranial Direct Current Stimulation (tDCS) in sample patients with early Alzheimer's…
- Trial name
- NCT06864910
- Testing
- anodal transcranial Direct Current Stimulation
- Where
- 2 sites in India
- Volunteers
- 40 people
- Sponsor
- National Institute of Mental Health and Neuro Sciences, India
Depression - Major Depressive Disorder, Generalized Anxiety Disorder (GAD)
Microbiota Modulation for Psychiatry Patients
The investigators aim to confirm pilot study findings (REB 119638) on the effects of delayed release apple cider vinegar (drACV).
- Conditions
- Depression - Major Depressive Disorder, Generalized Anxiety Disorder (GAD), Anxiety
- Trial name
- ACV-MTPIES-002 (NCT07899424)
- Testing
- Dietary Supplement: Acetate (Apple Cider Vinegar)
- Volunteers
- 62 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Musculoskeletal Disease, Obesity
Healthy Life Centers - Municipal Health Care Service for Lifestyle Changes - a Multicenter Intervention Study
A Healthy Life Center (HLC, 'Frisklivssentrale') is a public community-based health service providing lifestyle support programs for physical activity, smoking cessation and diet, to inhabitants with increased risk for…
- Conditions
- Musculoskeletal Disease, Obesity, Psychological Disorder
- Trial name
- NCT03026296
- Testing
- Healthy Life Center
- Where
- 4 sites in Norway
- Volunteers
- 1,022 people
- Sponsor
- Norwegian University of Science and Technology
Memory Encoding, Memory
Unconscious Mind Training
H22 - Unconscious Mind Training and Memory Encoding Phase 2.1 in progress. The core problem this clinical trial, H22, seeks to address is the pervasive challenge of modifying deeply ingrained, often unconscious, unwanted…
- Conditions
- Memory Encoding, Memory, Behavior Change Interventions, Habits
- Trial name
- NCT07597603
- Testing
- Intervention H22
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dream Video LLC
Schizophrenia
Linear and Non-linear Analysis of EEG Changes in Schizophrenia After Atypical Antipsychotics Medication
The purpose of this study is to evaluate clinical meaning of EEG changes in antipsychotic-treated patients with schizophrenia.
- Trial name
- NCT00698295
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Major Depressive Disorder
A Personalized Approach to Effects of Affective Bias Modification on Symptom Change and Rumination
This study evaluates the effect of a computerized intervention for depressive symptoms called Affective Bias Modification (ABM).
- Trial name
- NCT04137367
- Testing
- Affective bias modification
- Where
- Norway
- Volunteers
- 108 people
- Sponsor
- University of Oslo
Neoplasm, Colorectal, Cognitive Impairment
Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy
The purpose of this research study is to see how the brain changes in patients receiving chemotherapy (cytotoxic drug) treatment for colon or rectal cancer at Parkview Cancer Institute.
- Conditions
- Neoplasm, Colorectal, Cognitive Impairment, Cognitive Dysfunction, Cognitive Change
- Trial name
- Chemo Brain (NCT05014399)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Joseph McCollom
Alzheimer's Disease
A Study to Show That the Change of Attention Measure is Correlated With the Changes of Caregiver's Burden After Treatment With Galantamine in Patients With Alzheimer's Disease
The purpose of this study is to demonstrate that the change of attention measure is correlated with the changes of caregiver's burden after treatment with galantamine.
- Trial name
- NCT01734395
- Testing
- Galantamine
- Volunteers
- 1,882 people
- Sponsor
- Janssen Korea, Ltd., Korea
Dementia Prevention, Subjective Cognitive Impairment
The Brain Health PRO Online Risk Factor Reduction Study to Prevent Dementia
This study will recruit participants at risk for dementia to participate in an online educational program called Brain Health PRO (BHPro).
- Conditions
- Dementia Prevention, Subjective Cognitive Impairment, Mild Cognitive Impairment, Cognitive Change
- Trial name
- BHPROOF (NCT07364019)
- Testing
- Brain Health PRO
- Where
- Canada
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Alzheimer Disease
REXULTI General Use Results Survey in Patients With Hyperactivity, or Aggressive Behavior Associated With Alzheimer's Dementia
The purpose of this study is to evaluate safety of REXULTI in patients under daily clinical settings. In addition, information on efficacy will be collected.
- Trial name
- NCT06875986
- Testing
- Brexpiprazole (Rexulti)
- Where
- Japan
- Volunteers
- 200 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Noise Exposure, Sleep Disturbance
Low Particle Emission and Low Noise Tyres
This study will investigate the biological mechanisms linking sleep disruption by noise and the development of disease. In a laboratory sleep study, the investigators will play synthesised automotive tyre sounds, investigating…
- Conditions
- Noise Exposure, Sleep Disturbance, Sleep Hygiene, Metabolic Disturbance
- Trial name
- LEON-T (NCT05611619)
- Testing
- Tyre noise - continuous flow, Tyre noise - discrete events, High noise level
- Where
- Sweden
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Parenting, Substance Use
A Substance Use Adaptation of Fathering Through Change
This study is a randomized control trial of the Fathering Through Change intervention, delivered via text messaging, to fathers in recovery for substance use disorders.
- Trial name
- FTC-SUD (NCT04532619)
- Testing
- Fathering Through Change
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Dementia, Viral Infection
Electronic Medical Records to Increase Adherence to the Choosing Wisely Recommendations
Audit and Feedback (A\&F), a strategy aimed at promoting modified practice through performance feedback, is a method to change provider behaviour and reduce unnecessary medical services.
- Conditions
- Dementia, Viral Infection, Vitamin D Deficiency
- Trial name
- NCT05385445
- Testing
- Audit and Feedback
- Where
- Canada
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Depression
Women's Depression Treatment Study
The aim of the Women's Depression Treatment Study, based in a community mental health center, is to evaluate the effectiveness of Interpersonal Psychotherapy-Trauma in Community Settings (IPT-TCS) on improving depression and…
- Trial name
- NCT00843700
- Testing
- Interpersonal Psychotherapy-Trauma in Community Settings, Treatment as Usual
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- University of Rochester
Post Traumatic Stress Disorder
Studying the Modification of Attention Bias Remotely After Trauma
The investigators will complete an entirely remote randomized controlled trial (RCT) comparing 14 sessions of attention bias modification (ABM), attention control training (ACT), placebo neutral attention training, and a final…
- Trial name
- SMART (NCT04888169)
- Testing
- SMART Mobile App - Attention Bias Modification, SMART Mobile App - Attention Control Training, SMART Mobile App - Control
- Where
- United States
- Volunteers
- 872 people
- Sponsor
- University of California, San Francisco
Anxiety
Improving Emotional Wellbeing of University Students: Anxiety Management
University students' psychological well-being is a growing public health concern. The university period is a key time for psychological, social, and academic development, which can increase vulnerability to mental health…
- Trial name
- UniWELL-C (NCT07096154)
- Testing
- Group CBT Anxiety Management
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bogazici University
Alcohol Dependence, Alcohol Abuse
Motivation in Alcohol Treatment Facilities
The purpose of this study is to determine if and to what extend a composite measure of treatment motivation and behavior change motivation predicts alcohol treatment success.
- Trial name
- NCT00424112
- Where
- 2 sites in Germany
- Volunteers
- 450 people
- Sponsor
- University Medicine Greifswald
Obesity, Depression
Study of a Holistic Health Program for United Methodist Clergy
This study seeks to test a two-year intervention designed for United Methodist clergy. The intervention consists of: the stress reduction program Williams LifeSkills, adapted for clergy; the 10-session online weight loss program…
- Conditions
- Obesity, Depression, Diabetes, Hypertension
- Trial name
- SpiritedLife (NCT01564719)
- Testing
- Holistic health
- Where
- United States
- Volunteers
- 1,114 people, healthy volunteers welcome
- Sponsor
- Duke Clergy Health Initiative
Cognitive Dysfunction, Covid19
Improving Cognitive Health in COVID-19 Survivors
The primary objective of this study is to investigate the efficacy of AKL-T01, a remotely-delivered digital cognitive intervention, relative to a waitlist control in improving cognitive functioning in COVID-19 survivors.
- Trial name
- NCT04843930
- Testing
- AKL-T01
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Weill Medical College of Cornell University
Dementia
Montessori Based Activities for Dementia
The objectives of this study are to examine the feasibility of a culturally-adapted group-based Montessori Method for Dementia program in Chinese community and examine its effects on engagement and affect in community-dwelling…
- Trial name
- NCT04352387
- Testing
- Montessori Method for Dementia, Usual care
- Where
- Hong Kong
- Volunteers
- 108 people
- Sponsor
- Food and Health Bureau, Hong Kong
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