Clinical trials: Change; Mental
Social Phobia
Attention Bias Modification Treatment for Children With Social Anxiety
Children with social anxiety will be randomly assigned to either Attention Bias Modification Treatment (ABMT) designed to direct attention away from threat or a placebo control condition not designed to change attention patterns.
- Trial name
- NCT01397032
- Testing
- Attention Bias Modification Treatment (ABMT), Attention Control Condition
- Where
- Israel
- Volunteers
- 67 people
- Sponsor
- Tel Aviv University
Obesity, Binge-Eating Disorder
MindOb: A 12-month Computerized Mindfulness-based Intervention for Obese Individuals
The purpose of this study is to evaluate the efficacy of a daily 12-month computerized mindfulness-based intervention in obese patients diagnosed with Binge Eating Disorder (BED) on: impulsive eating, motivation toward exercise…
- Trial name
- MindOb (NCT02571387)
- Testing
- Mindfulness-based intervention
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University of Paris 5 - Rene Descartes
Emotional Disorder, Trauma and Stressor Related Disorders
Efficacy of a Transdiagnostic Guided Internet-Delivered Intervention for Emotional, Trauma and Stress-Related Disorders.
Emotional, trauma and stress-related disorders show high incidence, prevalence, morbidity, and comorbidity rates in Mexico. In recent decades, research findings indicate that cognitive behavioral interventions, from a…
- Conditions
- Emotional Disorder, Trauma and Stressor Related Disorders, Anxiety Disorders, Depression
- Trial name
- NCT05225701
- Testing
- Transdiagnostic guided internet-delivered intervention with synchronous assistance, Transdiagnostic self-guided internet-delivered intervention
- Where
- 6 sites in Mexico
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Psychological Disorder, Anxiety Disorders
Examining Change Mechanisms in Psychotherapy
This research project seeks to acquire a deeper understanding of the complex influences of common factors and specific ingredients in psychotherapy.
- Conditions
- Psychological Disorder, Anxiety Disorders, Depression, Eating Disorder
- Trial name
- CAMP (NCT03503981)
- Testing
- Psychotherapy
- Where
- Norway
- Volunteers
- 520 people
- Sponsor
- Modum Bad
Pain Management, Wound Care
The Application of Virtual Reality Goggles During the First Wound Dressing After Open Heart Surgery
The aim of this study is to examine the effect of virtual reality glasses, a non-pharmacological method used in pain and anxiety management in nursing practices, on the pain, anxiety, and vital parameters perceived by patients…
- Conditions
- Pain Management, Wound Care, Heart Surgery, Heart Surgery Via Sternotomy
- Trial name
- NCT07068594
- Testing
- Virtual Reality Goggles
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Aydin Adnan Menderes University
Noise Exposure, Sleep Disturbance
Metabolic and Cognitive Consequences of Noise-induced Sleep Disturbance
This study will investigate the biological mechanisms linking sleep disruption by noise and the development of disease. In a laboratory sleep study, we will play traffic sounds of different types (road, rail and air) and noise…
- Conditions
- Noise Exposure, Sleep Disturbance, Sleep Hygiene, Metabolic Disturbance
- Trial name
- NCT05319262
- Testing
- Pink noise exposure, Traffic noise
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Deliberate Self Harm, Borderline Personality Disorder
Adapted Dialectical Behaviour Therapy for Adolescents With Deliberate Self-Harm: A Pre-post Observational Study
The investigators conducted a pre-post naturalistic study regarding changes observed associated with a 15-week course of an adapted form of dialectical behaviour therapy for adolescents.
- Trial name
- NCT02988037
- Testing
- A-DBT-A
- Volunteers
- 33 people
- Sponsor
- University of Ottawa
Dementia, Dignity
Changes in the Perception of Personal Dignity Over the Course of Dementia
Dignity is an integral part of quality of life (QoL). Older adults often face with situations that are related with the development of dementia and that might significantly affect their feeling of personal dignity.
- Trial name
- DIDEM (NCT04443621)
- Testing
- questionnaire, in-depth interview
- Where
- 5 sites in Czechia
- Volunteers
- 500 people
- Sponsor
- Palacky University
Schizophrenia, Physical Activity
A Controlled Study With Remote Web-based Adapted Physical Activity (e-APA) in Psychotic Disorders
In this study, an APA program by web (e-APA) will be offered to two groups of participants (21 patients and 21 healthy volunteers (HV)) in remote video (use of the SAPATIC (Santé Activités Physiques Adaptées utilisant les…
- Conditions
- Schizophrenia, Physical Activity, Schizo Affective Disorder
- Trial name
- PEPSYV@SI (NCT03261817)
- Testing
- Physical activity (APA), Health Education program (HE)
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Alcohol Use Disorder
mHealth App for Changing Alcohol Use in Alaska Native American Indian People
For many people who have trouble with alcohol, peer support - the opportunity to share challenges, problem-solving strategies, and successes with supportive others - can be helpful.
- Trial name
- CIRCLE (NCT05326438)
- Testing
- CIRCLE mHealth app
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Southcentral Foundation
Attention Deficit Hyperactivity Disorder
ERP Based Single-dose Predictions of Stimulants
The purpose of this study was to see if the clinical outcome of stimulant medication (methylphenidate) in pediatric Attention Deficit Hyperactivity Disorder can be predicted on the bases of changes in Event Related Potentials…
- Trial name
- NCT02695355
- Testing
- Methylphenidate (MPH)
- Where
- Norway
- Volunteers
- 87 people
- Sponsor
- Ostfold Hospital Trust
Behavior Problem
Evaluation of the IY TCM Program in Norwegian School and Day-care Settings
The purpose of this study is to evaluate whether training teacher and staff in the Incredible Years (IY) Teacher Classroom Management (TCM) program reduce behavior problems and promote social competence in student aged 6-8 years…
- Trial name
- IYTCMNOR (NCT02962843)
- Testing
- IY TCM
- Volunteers
- 5,807 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Depressive Disorder, Treatment-Resistant
Efficacy, Safety, and Tolerability Study of AVP-786 as an Adjunctive Therapy in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment
The objectives of this 10-week study are to evaluate the efficacy, safety, and tolerability of AVP 786 as an adjunctive therapy compared with placebo in patients with major depressive disorder (MDD) who have shown an inadequate…
- Trial name
- NCT02153502
- Testing
- AVP-786 (d6-dextromethorphan hydrobromide and quinidine sulfate combination)
- Where
- 32 sites in United States
- Volunteers
- 206 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Pain, Burns
Decreasing REcurrent Pain and Anxiety in Medical Procedures With a Pediatric Population: Trial
Children with burn injuries experience severe pain intensity during medical procedures despite the increasing doses of analgesics.
- Conditions
- Pain, Burns, Child, Anxiety
- Trial name
- DREAM-T (NCT02947243)
- Testing
- VR distraction via Oculus Rift, Morphine
- Where
- Canada
- Sponsor
- St. Justine's Hospital
Obsessive Compulsive Disorder
Fear Extinction and Mechanisms of Change in Obsessive Compulsive Disorder
The purpose of this study is to find out more about how the brain stores emotional learning in obsessive-compulsive disorder (OCD). In particular, we would like to understand how human beings learn not to fear.
- Trial name
- NCT02467374
- Testing
- Behavior Therapy
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Delirium, Delirium in Old Age
Perioperative Pain and Delirium in Geriatric Patients With Hip Fracture
The objective of this trial will be to establish whether the ultrasound-guided suprainguinal fascia iliaca compartment block is capable of protecting geriatric patients with hip fracture from delirium as compared to placebo
- Conditions
- Delirium, Delirium in Old Age, Hip Fractures, Dementia
- Trial name
- Delirium-Hip (NCT04404959)
- Testing
- fascia iliaca compartment block with ropivacaine
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Aretaieion University Hospital
Hiv, Depression
Change My Story Task Shifted Mental Health Intervention
Psychological distress and depression are common among young people living with HIV (Y-PLWH) and negatively impact medication adherence and disease control.
- Conditions
- Hiv, Depression, Psychological Distress
- Trial name
- NCT06389565
- Testing
- Problem Solving Therapy, Change My Story
- Where
- Nigeria
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Substance Abuse Problem
Effect of Educational Program on Knowledge, Behavior and Involvement in Substance Abuse Among Adolescents
The aim of study was to effect of educational program by using behavior change wheel model on knowledge, behavior and involvement in substance abuse among adolescents.
- Trial name
- NCT07184164
- Testing
- Educational Program by Using Behavior Change Wheel Model, Routine Health Education
- Where
- Egypt
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Anxiety
Attention Bias Modification Training in Youth With Subthreshold Impairing Anxiety
This study is a pilot test of Attention Bias Modification Training (ABMT) among clinic referred children and adolescents with subthreshold impairing anxiety (i.e., anxiety and related impairment that fails to meet criteria for an…
- Trial name
- NCT02410967
- Testing
- Attention Bias Modification
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Florida International University
Major Depressive Disorder
Effects of a Single Dose of Amisulpride on Functional Brain Changes
This study is designed to investigate effects of a single dose of amisulpride on functional brain changes during reward- and motivation-related processing and at rest in healthy volunteers (HV) and in patients with Major…
- Trial name
- NCT05347199
- Testing
- Amisulpride Pill
- Where
- Germany
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Simone Grimm
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