Clinical trials: Change; Mental
Acrophobia
CBM in the Context of Exposure for Acrophobia
The proposed study will apply a one-session exposure treatment combined with CBM training modifying interpretational processing biases versus a sham training in acrophobic individuals.
- Trial name
- NCT05780203
- Testing
- One session exposure treatment, Active Cognitive Bias Modification training
- Where
- Germany
- Volunteers
- 81 people
- Sponsor
- Ruhr University of Bochum
Stress-related Problem
Change i Perceived Stress in School-age Students When Adding Physiotherapists to a School's Health Team.
School stress and performance requirements have been shown to contribute to mental illness among children and young people. Student health teams have an important role regarding mental health of children and young people.
- Trial name
- NCT05567913
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Vastra Gotaland Region
Alzheimer Disease
PET Changes in Alzheimer's Disease (AD)
The purpose of this study is to identify the earliest predictors of memory and brain deterioration in pre-clinical Alzheimer's disease using positron emission tomography (PET) to monitor brain glucose metabolism.
- Trial name
- NCT00094913
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Depressive Disorder, Major, Depression
Pilot Study: Investigating Mood Changes After Slow-wave Enhancement
The aim of this pilot project proposal is to test the hypothesis that decreased sleep slow-wave activity (SWA) observed in individuals with major depressive disorder (MDD) is related to mood dysfunction, and that manipulating SWA…
- Conditions
- Depressive Disorder, Major, Depression, Depression, Unipolar, Depressive Disorder
- Trial name
- SWE (NCT05146427)
- Testing
- Slow-wave enhancement
- Sponsor
- University of Pennsylvania
Depression, Anxiety
Evaluation of the Achieving Depression and Anxiety Patient Centered Treatment (ADAPT) Program
Depression and anxiety are increasingly common conditions for which primary care providers (PCPs) serve as the initial healthcare contact for most patients.
- Trial name
- ADAPT (NCT04839718)
- Testing
- ADAPT
- Where
- United States
- Sponsor
- Kaiser Permanente
Delirium, Cognitive Impairment
Incidence and Characteristics of Postoperative Cognitive Dysfunction in Elderly Quebec Francophone Patients
The purpose of this study is to determine what percentage of patients have cognitive problems (for example, memory or concentration difficulties) after surgery and anesthesia, what the characteristics of these problems are, and…
- Conditions
- Delirium, Cognitive Impairment, Cognitive Decline, Cognitive Change
- Trial name
- NCT03337282
- Testing
- Protocolized general anesthesia
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Obstructive Sleep Apnea, Sleep Disorder
Multidimensional Evaluation of Patients' Affected by Obstructive Apnea Syndrome (OSAS) Before and After Ventilotherapy
This observational study aims to evaluate multiple dimensions of health in patients with Obstructive Sleep Apnea Syndrome (OSAS), before and after three weeks of ventilotherapy.
- Conditions
- Obstructive Sleep Apnea, Sleep Disorder, Well-Being, Psychological, Cognitive Impairment
- Trial name
- MULTI-OSAS (NCT06312956)
- Testing
- Continuous Positive Airway Pressure Ventilotherapy
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- Istituto Auxologico Italiano
Inflammation, Inflammatory Response
Cannabis Observational Study on Mood, Inflammation, and Cognition
This project examines the effects of cannabis on cognition and other domains of function and whether those effects are dependent upon the ratio of THC to CBD in the product.
- Conditions
- Inflammation, Inflammatory Response, Mood, Cognitive Change
- Trial name
- COSMIC (NCT03522103)
- Where
- United States
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cancer, Physical Activity
Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors
The purpose of this study is to conduct a 6-month pilot randomized trial to determine the feasibility and acceptability of theory-based mobile weight loss interventions for survivors of adolescent and young adult cancer (AYAs).
- Conditions
- Cancer, Physical Activity, Cancer Survivorship, Mental Health
- Trial name
- AYAConnect (NCT06171945)
- Testing
- AYA Connect intervention, Positive Psychology (PP) intervention, Positive Psychology Plus (PP+) intervention
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
ASD, Autism Spectrum Disorder
The Effects of Tailored Judo Training and Nutritional Counseling on Physical Fitness and Body Composition in Children With Autism: A Study Including Blood Morphology and Genetic Analysis
The present research project aims to testing adapted judo training as a form of supportive developmental therapy, combined with nutritional counseling, to influence physical fitness, dietary habits, body composition, body…
- Conditions
- ASD, Autism Spectrum Disorder, Autism Spectrum Disorder High-Functioning, Autism Spectrum
- Trial name
- AdaptedJudoASD (NCT07442994)
- Testing
- Adapted judo training for children and adeloscence with and without autism spectrum disorder - training in integrated groups
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Cognitive/Functional Effects, Depression
Study of Physical and Mental Health of Older Patients With Newly Diagnosed Cancer
RATIONALE: Gathering information from older patients with newly diagnosed cancer may help doctors learn more about the risks of functional decline.
- Conditions
- Cognitive/Functional Effects, Depression, Hematopoietic/Lymphoid Cancer, Malnutrition
- Trial name
- NCT00769951
- Testing
- medical chart review, questionnaire administration, cognitive assessment
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Case Comprehensive Cancer Center
Eating Disorders, Behavior, Eating
Culinary Art Therapy Group for Adults With Eating Disorders.
The study will assess the influence of culinary art therapy group (a new therapeutic tool) for adults with eating disorders. It will assess changes in thinking patterns and behavioural patterns associated with food and eating.
- Conditions
- Eating Disorders, Behavior, Eating, Relationship, Family, Cognitive Change
- Trial name
- NCT04538846
- Testing
- Culinary art therapy
- Where
- Israel
- Volunteers
- 52 people
- Sponsor
- Hadassah Medical Organization
Low Executive Function in Children
Modeling and Testing Change in Mental Abilities in Childhood
Children with low executive function, working memory and attention skills in childhood not only do poorly at school, but also go on to do poorly on social, health, and financial indicators in adulthood.
- Trial name
- NCT02459873
- Testing
- Computer games to assess change in executive function skills
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Psoriasis, Metabolic Syndrome
Response of Metabolic Syndrome and Sexual Dysfunction to Lifestyle Changes in Men With Psoriasis
complaint of sexual dysfunction and metabolic syndrome are highly reported in men with psoriasis
- Conditions
- Psoriasis, Metabolic Syndrome, Erectile Dysfunction
- Trial name
- NCT05632042
- Testing
- lifestyle modification (exercise and control of diet)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Disease Bowel, Crohn Disease
Evaluation of Sleep Changes in Inflammatory Bowel Diseases (IBD) Patients.
Inflammatory Bowel Diseases (IBD) go through two phases: flare and remission. Prediction of flares and identification of patients in remission but at high risk of flare are a major issue when taking care of IBD patients.
- Conditions
- Disease Bowel, Crohn Disease, Ulcerative Colitis
- Trial name
- RECIDREAM (NCT05835973)
- Testing
- Sleep activity, Questionnaires
- Where
- 4 sites in France
- Volunteers
- 216 people
- Sponsor
- Hospices Civils de Lyon
Alzheimers Disease
Identifying Potential Effects of Liraglutide on Degenerative Changes
Today Alzheimers disease can not be cured. Animal experiments have shown that the hormone GLP-1 can improve memory in Alzheimer-prone mice.
- Trial name
- NCT01469351
- Testing
- Liraglutide, non-active study drug
- Where
- Denmark
- Volunteers
- 34 people
- Sponsor
- University of Aarhus
Schizophrenia, Schizoaffective Disorder
Body Mass Index (BMI) and Metabolic Changes Following Switch to Aripiprazole From Olanzapine, Risperidone and Quetiapine
Weight gain is a serious, common side effect of many antipsychotic medications. On average, the highest amounts of weight gain are found to occur in people taking clozaril and olanzapine, but with significant weight gain occuring…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Mood Disorders
- Trial name
- NCT00312598
- Testing
- Aripiprazole
- Volunteers
- 30 people
- Sponsor
- University of North Carolina, Chapel Hill
Major Depressive Disorder (MDD), Treatment Resistant Depression (TRD)
Accelerated iTBS for Major Depression
Major depressive disorder (MDD) is a common and disabling psychiatric condition, and many patients do not achieve adequate response to standard antidepressant treatments.
- Trial name
- AIM-D (NCT07603804)
- Testing
- Accelerated Intermittent Theta Burst Stimulation (iTBS)
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Istanbul University - Cerrahpasa
Schizophrenia, Psychotic Disorders
A Study to Compare Disease Progression and Modification Following Treatment With Paliperidone Palmitate Long-Acting Injection or Oral Antipsychotics in Participant's With Recent-onset Schizophrenia or Schizophreniform
The purpose of the study is to compare effectiveness of paliperidone palmitate (PP: paliperidone palmitate once-monthly and 3-month injections) versus oral antipsychotic (OAP [that is oral paliperidone extended release {ER}, oral…
- Trial name
- DREaM (NCT02431702)
- Testing
- Aripiprazole, Haloperidol, Olanzapine
- Where
- 38 sites in United States, Brazil and 1 more
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- Janssen Scientific Affairs, LLC
Internet Gaming Disorder, Social Media Addiction
Chatbot Intervention to Reduce Common Digital Addictions, Sedentary Behaviors and Mental Distress Among Adolescents
The goal of the study is to investigate the efficacy of a secondary low-intensity stage of change (SoC) and motivational interviewing (MI)-based Chatbot-assisted intervention in reducing digital addictions in adolescents with…
- Trial name
- NCT06821373
- Testing
- Chatbot, Control
- Where
- Hong Kong
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
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