Clinical trials: Change; Mental
Mild Cognitive Impairment
Tailored Mediterranean Lifestyle Education in Patients With Mild Cognitive Impairment
Evidence suggests that a Mediterranean diet can have a beneficial effect on brain health. Mild cognitive impairment (MCI) describes problems with brain function such as difficulty with day-to-day memory and concentration.
- Trial name
- NCT03265522
- Testing
- "ThinkMed" resource at baseline, Standard Care Control, "ThinkMed" resource (staged)
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Queen's University, Belfast
Cognition, Brain Health
Brain Response to an Intervention Using Guided, At-Home Technology for the Mind
The objective of this study is to assess the effectiveness of two digital programs for providing mental stimulation, improving cognition, and inducing changes in brain structure and function.
- Conditions
- Cognition, Brain Health, Brain Structure, Brain Function
- Trial name
- BRIGHT-Mind (NCT05912556)
- Testing
- Digital Program 1, Digital Program 2
- Where
- United States
- Volunteers
- 817 people, healthy volunteers welcome
- Sponsor
- Lumos Labs, Inc.
Plasma microRNA in Patients With Genetic Susceptibility to Mental Disorders
Study on the Difference of Plasma microRNA Expression in Patients With Genetic Susceptibility to Mental Disorders
Schizophrenia (Schizophrenia,Sc), biphasic affective disorder (Bipolar disorder,BPD), major depression (major depressive disorder,MDD), anxiety disorder (Anxiety disorder,An) and other mental disorders have obvious family…
- Trial name
- NCT03999931
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Domestic Violence, Substance Abuse
Fathers for Change for Men With Co-occurring Domestic Violence and Substance Abuse
Social service systems rarely acknowledge the status of men as fathers in the conceptualization and delivery of treatment for substance abuse or domestic violence.
- Conditions
- Domestic Violence, Substance Abuse, Parenting
- Trial name
- NCT01385553
- Testing
- Fathers for Change, Individual Drug Counseling
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Yale University
Alcohol Abuse or Dependence
Guided Self-Change Prevention Program for Alcohol Abuse in Adolescents in Educational Settings
This study corresponds to a pretest-posttest randomized experimental design with two arms. Arm 1 includes Guided Self-Change program, and Arm 2 a psychoeducational program to promote healthy habits.
- Trial name
- PREVENALC (NCT05281172)
- Testing
- Guided Self-Change therapy (GSC), Psychoeducation program about healthy habits
- Where
- Spain
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Psychosis
Can Imagination Change Upsetting Memories of Trauma?
Research suggests that imagination is a powerful tool to change images inside our heads (e.g. memories) and make them less upsetting. It is thought that this occurs through changing the meaning attached to the memory (e.g.
- Trial name
- NCT03607630
- Testing
- Imagery Rescripting
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- King's College London
Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder
HBOT Effects on First Responders' Cognition and Well-Being
The goal of this study is to examine changes in cognitive functioning and post-concussive symptoms following hyperbaric oxygen therapy (HBOT) in current and former first responders with a history of traumatic brain injury.
- Conditions
- Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder, Anxiety, Depression
- Trial name
- NCT07852728
- Testing
- Hyperbaric Oxygen Therapy (HBOT)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Summit Hyperbarics and Wellness
Critical Illness, Pain
Pervasive Sensing and AI in Intelligent ICU
Important information related to the visual assessment of patients, such as facial expressions, head and extremity movements, posture, and mobility are captured sporadically by overburdened nurses, or are not captured at all.
- Conditions
- Critical Illness, Pain, Delirium, Confusion
- Trial name
- NCT05127265
- Testing
- Video Monitoring, Accelerometer Monitoring, Noise Level Monitoring
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Florida
Hepatitis C, Liver Diseases
Improving Hepatitis C Treatment in Injection Drug Users
The overall goal of the research project is to improve the outcome of medical care for injection drug users (IDUs) with Hepatitis C viral (HCV) infection.
- Conditions
- Hepatitis C, Liver Diseases, Drug Abuse, Alcoholism
- Trial name
- NCT00148031
- Testing
- Pegylated Interferon and Ribavirin, Psychosocial, On-site (MMT Clinic) HCV evaluation and treatment
- Where
- 2 sites in United States
- Volunteers
- 111 people
- Sponsor
- State University of New York - Upstate Medical University
Emergence Delirium
Namsos Anaesthesia Children Outcome Study
Behavioral disturbances are often seen in children after anesthesia both immediately after surgery (emergence delirium) and after discharge from hospital.
- Trial name
- NACOS (NCT04292457)
- Testing
- Propofol, Sevoflurane
- Where
- 2 sites in Norway
- Volunteers
- 761 people
- Sponsor
- Helse Nord-Trøndelag HF
Mood Disturbance, Mood Change
Mood and Cognitive Effects of Psilocybin in Healthy Participants
This study is seeking to find the optimal microdose or low dose of psilocybin (magic mushrooms) that provides general enhancements to mood, memory, sleep, and other measures of general well-being without any hallucinogenic…
- Conditions
- Mood Disturbance, Mood Change, Sleep Disturbance, Drug Effect
- Trial name
- MELO (NCT05252598)
- Testing
- Psilocybin, Inonotus Obliquus Whole Extract
- Volunteers
- healthy volunteers welcome
- Sponsor
- Optimi Health Corporation
Eating Disorders, Mood Disorders in Children and Adolescents
Psychotropic-Drug-induced QT Prolongation and ECG Monitoring in the Pediatric Population
Electrocardiogram (ECG) Q-T prolongation is a cardiac electrophysiological disorder associated with the occurrence of arrhythmias potentially fatal.
- Conditions
- Eating Disorders, Mood Disorders in Children and Adolescents, Psychotic Disorder, QTc Intervals Changes
- Trial name
- NCT06870006
- Where
- 6 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Meyer Children's Hospital IRCCS
Anxiety, Preoperative Anxiety
Effect of Parental Presence on Anxiety of Children During Induction of Anesthesia
Anxiety is when children feel scared, worried, or nervous before or during anesthesia induction. This can happen because they don't know what's happening, are scared of the hospital or medical equipment, or are worried about…
- Trial name
- PPIA (NCT06709443)
- Where
- Pakistan
- Volunteers
- 75 people
- Sponsor
- Liaquat National Hospital & Medical College
Mental Disorders, Neurotic Disorders
Dynamics of Psychotherapy and Treatment Outcomes
The study is a 3-month controlled trial that aims to measure changes in patient's capacity (mindfulness, resilience, insight, working alliance) and intensity of neurotic symptoms.
- Conditions
- Mental Disorders, Neurotic Disorders, Personality Disorders
- Trial name
- NCT07017543
- Testing
- Psychotherapy Process-Outcome Study in Group Therapy
- Where
- Poland
- Volunteers
- 89 people
- Sponsor
- University Hospital in Krakow
Postpartum Depression
A Long-Term Study of Patient-Reported Changes in Postpartum Depression Symptoms in People Starting Zuranolone
In this study, researchers will learn how postpartum depression symptoms may change after people first start taking zuranolone. This is a drug available for doctors to prescribe for people with postpartum depression, also known…
- Trial name
- NCT07398469
- Testing
- Zuranolone
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Biogen
Hyperbaric Oxygen Therapy, Mild Cognitive Impairment
MRI Brain Changes Induced by Hyperbaric Oxygen Therapy in Brain Injury Patients
In our institute there is ongoing treatment of brain injury patients with Hyperbaric oxygen therapy. These patients undergo neuro-cognitive function tests in addition to brain imaging studies before and after treatment.
- Trial name
- NCT02452619
- Testing
- Hyperbaric oxygen therapy
- Where
- 2 sites in Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
Posttraumatic Stress Disorder (PTSD), Depression - Major Depressive Disorder
To Investigate the Change of Brain and Autonomic Function From Different Protocols of Repeated Transcranial Magnetic Stimulation Therapy for Patients With Post-traumatic Stress Disorder Comorbid Major Depressive Disorder
This study aims to investigate the immediate neurophysiological and autonomic effects of two noninvasive brain stimulation protocols-prolonged intermittent theta-burst stimulation (prolonged iTBS) and high-frequency repetitive…
- Trial name
- NCT07327385
- Testing
- Prolonged Intermittent Theta-Burst Stimulation (prolonged iTBS), High-Frequency Repetitive Transcranial Magnetic Stimulation (HF-rTMS)
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Tobacco Use Disorder/Cigarette Smoking
Smoking Cessation Intervention for Young Adults Using MTM: A Randomized Controlled Trial
The goal of this clinical trial is to evaluate whether a Multi-Theory Model (MTM)-based behavioral intervention can effectively promote smoking cessation and support behavior change in young adult cigarette smokers aged 18 to 29…
- Trial name
- NCT07104006
- Testing
- Multi-Theory Model (MTM)-Based Smoking Cessation Program
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Nevada, Las Vegas
Physical Inactivity, Overweight and Obesity
A Pilot Factorial Trial of an Integrated Lifestyle Intervention
This study plans to learn more about the feasibility and acceptability of integrating the Move physical activity support program within an existing lifestyle intervention program.
- Trial name
- NCT06116435
- Testing
- Prevent T2, Move group-based classes, Fitness Membership
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Stress Disorders, Post-Traumatic, Sleep Initiation and Maintenance Disorders
A Transdiagnostic Sleep Health Intervention for Veterans With PTSD
Sleep disturbance is a major problem in Veterans with posttraumatic stress disorder (PTSD). This study will test a version of a sleep treatment that's been shown to be effective in the general population, with some changes to…
- Trial name
- NCT06549049
- Testing
- TranS-C for PTSD, Sleep Psychoeducation Control
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- VA Office of Research and Development
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.