Clinical trials: Change; Mental
Emotion Regulation
Improving Emotional Wellbeing of University Students: Emotion Regulation
University students' psychological well-being is a growing public health concern. University life involves major psychological, social, and academic changes, increasing vulnerability to mental health issues.
- Trial name
- UniWELL-D (NCT07096141)
- Testing
- DBT-informed Group Psychotherapy for Emotion Regulation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bogazici University
Alzheimer Disease, Mild Cognitive Impairment
A Scalable Nutrition Adherence Intervention
Objective 1: To scale-up the nutrition adherence intervention for testing in racially diverse rural communities in North Florida. The investigators hypothesize that: 1.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Adherence
- Trial name
- NCT06121986
- Testing
- Improving Cognitive Aging through Nutrition (ICAN) Adherence Program, Improving Cognitive Aging through Nutrition, Mediterranean diet
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Florida State University
Problem Drinking
Changing Impulsivity With Mindful Breathing Therapy to Reduce Problem Drinking
The investigators plan to establish the efficacy of a novel breathing-based mindfulness training (BBMT, a much simplified, easy-to-use version of standard MM) for problem drinking, and test whether impulsivity mediates this…
- Trial name
- BBMT (NCT02527720)
- Testing
- Mindfulness Therapy
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Postoperative Cognitive Dysfunction, Coronary Artery Disease
Short-Term and Long-Term Cognitive Outcomes in Adults After Cardiac Surgery
Adults with coronary artery disease (250 patients) undergoing cardiac surgery participated in the study. The aim is to investigate short-term and long-term cognitive outcomes and the patterns of organization of functional brain…
- Trial name
- NCT05172362
- Where
- Russia
- Volunteers
- 250 people
- Sponsor
- Research Institute for Complex Problems of Cardiovascular Diseases, Russia
Alcohol Use Disorder, Alcohol Abuse
Neurocognitive and Neurobehavioral Mechanisms of Change Following Psychological Treatment for Alcohol Use Disorder
Alcohol Use Disorder (AUD) is a significant public health problem, with prevalence rates of 13.9% for current and 29.1% for lifetime diagnosis (Grant et al., 2015).
- Conditions
- Alcohol Use Disorder, Alcohol Abuse, Alcohol Drinking, Alcohol Dependence
- Trial name
- ABQTREAT (NCT03842670)
- Testing
- Cognitive Behavior Therapy, Mindfulness Based Relapse Prevention
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- University of New Mexico
Musculoskeletal Pain, Cognitive Change
Health, Wellbeing and Performance in Law Enforcement Workers
This study aims to assess current health and fitness of law enforcement workers in various roles, and to evaluate the impact of an exercise intervention on markers on physical and mental wellbeing in this population.
- Conditions
- Musculoskeletal Pain, Cognitive Change, Occupational Stress, Inflammation
- Trial name
- NCT04204486
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University College, London
Autism Spectrum Disorder
Adapted Judo for Children With Autistic Spectrum Disorders
The project is aligned with one of the overall: To promote social inclusion and equal opportunities, encouraging participation in sport and physical activity.
- Trial name
- AUTJUDO (NCT04523805)
- Testing
- Adapted judo programme
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Ramon Llull
Alzheimer's Disease
Brain Changes by Rivastigmine According to Butyrylcholinesterase Alleles
Butyrylcholinesterase (BuChE) activity is increasing in Alzheimer Disease (AD) process (Lane et al., 2006). BuChE wild type has stronger butyrylcholine esterase activity than BuChE K variant allele and this strong activity can…
- Trial name
- NCT02063269
- Testing
- Rivastigmine
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Seoul National University Hospital
Pre-Eclampsia, Neurocognitive Dysfunction
Changes in fMRI and Neurocognitive Function in Women With Pre-eclampsia
This is a pilot study assessing fMRI changes and neurocognitive function in women with pre-eclampsia and healthy controls. Neurocognitive testing will be done during pregnancy and after delivery up to 2-6 weeks postpartum.
- Trial name
- NCT03863639
- Testing
- Neuroimaging Procedures, Neuropsychological Assessment Procedures
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Duke University
Suicidal Ideation, Depressive Symptoms
Task-Shifting Adapted IPT-A for Youth Suicide Prevention
The goal of this randomized pragmatic clinical trial is to examine the feasibility, acceptability, and mechanisms of change of a brief adaptation of Interpersonal Psychotherapy for Adolescents (BIPT-A), adapted and task-shifted…
- Conditions
- Suicidal Ideation, Depressive Symptoms, Adolescent Mental Health
- Trial name
- NCT07383831
- Testing
- Adapted Brief Interpersonal Psychotherapy for Adolescents (IPT-A LAZOS), Usual Community Center Services
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Boston College
Cognition, Embolism, Fat
Cognition Following Computer Assisted Total Knee Arthroplasty
A significant number of patients experience postoperative cognitive changes following total joint arthroplasty. Among other causes, the mental status change may be the result of fat and bone marrow debris embolization.
- Trial name
- Minimental (NCT00830986)
- Testing
- Total Knee Arthroplasty Implant (Scorpio®)
- Volunteers
- 100 people
- Sponsor
- Rothman Institute Orthopaedics
Cognitive Dysfunction, Emergence Delirium
Effects of Hypothermia on Delayed Neurocognitive Recovery (DNR): an Observational Trial Among Patients Undergoing Cardiac-Surgery
Post-operative cognitive dysfunction is a common disease in patient undergoing general anaesthesia, especially in older patients.
- Conditions
- Cognitive Dysfunction, Emergence Delirium, Hypothermia
- Trial name
- DNR (NCT03636074)
- Testing
- Hypothermia during Extracorporeal Circulation
- Where
- Italy
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Padova
Sleep Deprivation, Obesity
Sleep and Metabolism
The goal of this study is to uncover sleep and circadian mechanisms contributing to adverse metabolic health. The protocol is a 21 day (7 outpatient days, 14 inpatient days) mechanistic randomized-crossover study designed to…
- Conditions
- Sleep Deprivation, Obesity, Glucose Intolerance, Weight Gain
- Trial name
- SAM (NCT05775627)
- Testing
- Sleep Restriction
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Schizophrenia
A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia
Schizophrenia is a common and severe psychiatric illness characterized by extreme disturbances of cognition and thought, affecting language, perception and sense of self.
- Trial name
- NCT07145918
- Testing
- Emraclidine
- Where
- 7 sites in United States
- Volunteers
- 268 people
- Sponsor
- AbbVie
Major Depression, Treatment
fMRI Study of Treatment Changes in Major Depression
The overall purposes of this research are to determine if Cognitive Behavioral Therapy (CBT) has the same healing effect on the brain for people with depression as traditional antidepressants do, and in comparison to healthy…
- Trial name
- NCT01027559
- Testing
- Sertraline, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Alcohol Use Disorder (AUD), Cocaine Use Disorder (CUD)
Web-based Alcohol- or Cocaine-specific Inhibition Training in Adolescents and Young Adults With Substance Use Disorder
Substance misuse is one of the most common risk factors for health problems and premature death among adolescents and young adults worldwide.
- Conditions
- Alcohol Use Disorder (AUD), Cocaine Use Disorder (CUD), Substance Use Disorder (SUD)
- Trial name
- WAIT-AYA (NCT07071779)
- Testing
- Substance-specific inhibition training, Control training
- Where
- Switzerland
- Volunteers
- 210 people
- Sponsor
- University of Bern
Stress, Mental Health
PPI and Mindfulness App for Parents of Children with a NDD
An app based on positive psychology and mindfulness to support the mental well-being of parents of children with a Neurodevelopmental Disorder (NDD) was developed and will be evaluated on effectiveness.
- Conditions
- Stress, Mental Health, Mental Well-being
- Trial name
- Adappt (NCT06248762)
- Testing
- Adappt
- Where
- Netherlands
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- University of Twente
Dyslexia
Static and Dynamic Balance in Children With Dyslexia
Dyslexia is described as a learning disability with a neurological origin. It is a widespread disease, characterized by difficulties in recognition of words, spelling, and decoding.
- Trial name
- NCT04386161
- Testing
- Scheduled exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Marmara University
Body Weight Changes, Eating Disorder Symptom
Body Weight Regulation, Disordered Eating Behaviour, and Experiences of Sexual Harassment in Female Martial Art Athletes
Athletes in martial arts compete in categories separated by body weight, hence, many athletes need to adjust their habitual body weight during periods with competition preparation.
- Conditions
- Body Weight Changes, Eating Disorder Symptom, Sexual Harassment, Covid19
- Trial name
- FMAB (NCT04559542)
- Where
- Norway
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Lean Body Mass, Cannabis
The Effect of Cannabidiol on Lean Body Mass in Patients Receiving Chemotherapy
An intervention study on the effect of cannabidiol on lean body mass in cancer patients receiving chemotherapy, at the department of Clinical Oncology at Zealand University Hospital, Roskilde, Denmark.
- Conditions
- Lean Body Mass, Cannabis, Cancer, Nausea
- Trial name
- NCT04585841
- Testing
- Cannabidiol
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- University of Copenhagen