Clinical trials: Change; Mental
Social Anxiety Disorder
Attention Bias Modification Treatment (ABMT) and Cognitive-Behavioral Group Therapy (CBGT) in Social Anxiety Disorder
This RCT examines the effectiveness of Attention Bias Modification Treatment (ABMT) as an augment to Cognitive-Behavioral Group Treatment (CBGT) for Social Anxiety Disorder (SAD) in adults. It is expected that ABMT vs.
- Trial name
- ABMT+CBGT (NCT02338453)
- Testing
- Active Attention Bias Modification Treatment
- Where
- 2 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Yair Bar-Haim
Mild Cognitive Impairment, Lack of Physical Activity
Change in Executive Function and IADL Using a Virtual Supermarket Environment Among People With MCI
The aim of the study is to investigate the feasibility of using a virtual supermarket as an intervention tool for overcoming deficits in executive function as well as enhancing IADL performance among persons with Mild Cognitive…
- Trial name
- EF-VAPS (NCT01103453)
- Testing
- Virtual Action Planning Supermarket (VAP-S) Software
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Carmel Medical Center
Social Phobia
Attention Bias Modification Training in Social Phobia/Social Anxiety Disorder
A study investigating six different versions of a computerized attention bias modification internet program in the treatment of social phobia / social anxiety disorder.
- Trial name
- SOFIE-11 (NCT01463137)
- Testing
- Attention bias modification
- Where
- Sweden
- Volunteers
- 129 people
- Sponsor
- Umeå University
Disordered Eating Behaviors, Binge Eating
Enhanced Cue Exposure Therapy for Negative Emotional Eating
The current study aims to evaluate the efficacy of Enhanced Cue Exposure Therapy (E-CET) in reducing negative emotional eating (NEE), compared to an active control intervention, behavioral lifestyle intervention (BLI), in a…
- Trial name
- NCT06012045
- Testing
- Enhanced Cue Exposure Therapy, Behavioral Lifestyle Intervention
- Where
- Hong Kong
- Volunteers
- 138 people
- Sponsor
- The University of Hong Kong
Binge Eating Disorder, Overweight and Obesity
Neural Response to Food Stimuli: fMRI Changes Following Cognitive Behavioral Therapy for Binge Eating Disorder
The purpose of this research is to conduct a randomized controlled trial (RCT) assessing the impact of CBT on neural responses to binge eating stimuli.
- Trial name
- NCT03604172
- Testing
- Cognitive behavioral therapy, Waitlist
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Psychosis
Culturally Adapted Psychosocial Interventions for Early Psychosis in a Low-resource Setting
Primary Aims: To determine the clinical efficacy of Culturally adapted Cognitive Behavioral Therapy (CaCBT) and Culturally adapted Family Intervention (CulFI) compared to Treatment As Usual (TAU) on reducing overall symptoms of…
- Trial name
- CaPSI (NCT05814913)
- Testing
- CaCBT for psychosis, Culturally adapted Family Intervention (CulFI) for psychosis
- Where
- Pakistan
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Living and Learning
Obesity, Schizophrenia
Pilot Trial of Naltrexone for Obesity in Women With Schizophrenia
The purpose of this clinical trial is to find out how effective low dose oral naltrexone is on reducing body weight when compared to placebo in women with schizophrenia and schizoaffective disorder.
- Conditions
- Obesity, Schizophrenia, Schizoaffective Disorder
- Trial name
- NCT00793780
- Testing
- Naltrexone 25mg
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Yale University
Social Anxiety Disorder
Flushing in Social Anxiety Disorder on Cipralex
To add to our understanding of the relationship between blushing, symptom severity and potential mechanisms that underlie blushing in patients with SP, we propose comparing SP patients' vascular responses to topical m-N pre and…
- Trial name
- NCT00485888
- Testing
- Cipralex
- Where
- Canada
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- START Clinic for Mood and Anxiety Disorders
Alzheimer Disease
Evaluation System for Lecanemab Efficacy Using Gold Electrode ECL to Monitor Alzheimer's Biomarkers
This study aims to evaluate the therapeutic efficacy of Lecanemab in patients with Alzheimer's disease. The researchers will use a novel detection method based on mesoporous gold electrode surface-enhanced…
- Trial name
- ECL-Lecanemab (NCT07688460)
- Testing
- Lecanemab
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Cognitive Change, Cognitive Impairment
The Everyday Function Intervention Trial
Loss of independence, cognitive decline, and difficulties in everyday function are areas of great concern for older adults and their families.
- Conditions
- Cognitive Change, Cognitive Impairment, Healthy Aging, Dementia
- Trial name
- EFIT (NCT04651582)
- Testing
- Cognitive Training, Cognitive Stimulating Activities
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Clemson University
Psychological Distress
Practice-Based Evidence in Psychotherapy in Ecuador
This is a naturalistic study implementing a routine outcome monitoring system to track clients' change and outcomes at the Centro de Psicología Aplicada (CPA) of the Universidad de Las Américas in Quito, Ecuador
- Trial name
- NCT05343741
- Testing
- Psychological Intervention
- Where
- Ecuador
- Volunteers
- 340 people
- Sponsor
- Universidad de las Americas - Quito
Psychiatric Disorders
Changes Following Inpatient Child-oriented Family Treatment
Children receiving IFT (intensive family therapy) were assessed for symptom profile and global functioning before admission, 3 months after discharge and 1 year after discharge.
- Trial name
- NCT00184327
- Testing
- Intensive family therapy - inpatient, Diagnostic assessment - child and adolescent psychiatry
- Where
- 5 sites in Norway
- Volunteers
- 150 people
- Sponsor
- Norwegian University of Science and Technology
Attention Deficit Hyperactivity Disorder
Group Dialectical Behavior Therapy as add-on Treatment for Adults With Attention Deficit/Hyperactive Disorder
Attention-Deficit/Hyperactive Disorder (ADHD) in adults is associated with global impairments and deficits in quality of life. The ADHD functional impairments during adulthood usually persist even after adequate medication…
- Trial name
- NCT03326427
- Testing
- Skill Training Group of the Dialectical Behavior Therapy, Treatment as Usual
- Where
- Brazil
- Volunteers
- 31 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Post Acute COVID 19 Syndrome, Memory Impairment
HOBSCOTCH for People With Post Acute COVID-19 Syndrome (PACS)
The goal of this pilot study is to assess the feasibility of adapting and delivering the existing home-based epilepsy self-management intervention, HOBSCOTCH, for people with Post Acute Covid Syndrome (PACS).
- Conditions
- Post Acute COVID 19 Syndrome, Memory Impairment, Memory Dysfunction, Cognitive Dysfunction
- Trial name
- NCT06391489
- Testing
- HOBSCOTCH-PACS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Nicotine Dependence
Smoked Nicotine Induced Changes in Hormone Function, Mood States and Behaviors
The proposed clinical studies will evaluate the acute effects of nicotine on the hypothalamic-pituitary-gonadal axis in women to test the hypothesis that nicotine alters gonadal steroid hormones, and/or disrupts feedback…
- Trial name
- NCT01636323
- Testing
- Nicotine
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Obesity (Disorder), Obesity & Overweight
Dramatherapy for Psychological and Social Well-Being in Obesity and Bariatric Care
Obesity is currently a major public health challenge in France, particularly in the Hauts-de-France region, where prevalence exceeds 20% of the adult population.
- Conditions
- Obesity (Disorder), Obesity & Overweight, Eating Disorders, Bariatric Surgery
- Trial name
- NCT07685483
- Testing
- Adapted Physical Activity, Dramatherapy
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Universite du Littoral Cote d'Opale
Sleep Bruxism, Masseter Muscle Hypertrophy
Changes in Electromyographic Activity in Aligner Treatment of Adult Patients With and Without Nocturnal Bruxism
The purpose of the study is to evaluate the effectiveness of clear aligners on the symptoms and signs reported by bruxism patients.
- Conditions
- Sleep Bruxism, Masseter Muscle Hypertrophy, Grinding Teeth
- Trial name
- EMG_BRUX (NCT06343194)
- Testing
- Bruxoff ®
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cognitive Impairment, Cognitive Change
Validation of a Digital Self-Administered Cognitive Screening Tool: MoCA-XpressO
The investigators conducted a validation study for the Montreal Cognitive Assessment (MoCA)-XpressO compared to the digital-MoCA test (version 8.1) as the gold standard.
- Conditions
- Cognitive Impairment, Cognitive Change, Cognitive Deficit, Assessment, Self
- Trial name
- MoCA (NCT05879562)
- Testing
- MoCA-Xpresso
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- MoCA Clinic and Institute
Alcohol Dependence, PTSD
Modification of Cognitive Processing Therapy (CPT-C) for PTSD and Alcohol Dependence
Objective: To develop a detailed treatment manual that modifies the existing CPT-C treatment protocol to allow for concurrent treatment of PTSD and AD, and to obtain some pilot data regarding its efficacy.
- Trial name
- NCT00639288
- Testing
- modified CPT-C
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Yale University
Stroke, Aphasia
Recovery From Post-Stroke Aphasia With rTMS Targeting Left or Right Anterior Temporal Lobe
This project aims to tailor repetitive Transcranial Magnetic Stimulation (rTMS) target to the clinical profile of post-stroke aphasia, specifically focusing on lexicosemantic impairments, to enhance recovery.
- Trial name
- ATLAS (NCT07608588)
- Testing
- continuous Theta Burst Stimulation, intermittent Theta Burst Stimulation, Semantic Feature Analysis
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of South Carolina
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