Clinical trials: Cheek
Lips Enhancement, Perioral Wrinkles
Evaluation of Facial HA Dermal Fillers in Real-Life Conditions
The goal of this post-market interventional study is to confirm, under real-life conditions, the safety and performance of hyaluronic acid-based dermal fillers intended to modify skin anatomy and facial appearance.
- Conditions
- Lips Enhancement, Perioral Wrinkles, Nasolabial Fold Wrinkles, Cheek Augmentation
- Trial name
- NCT07255261
- Testing
- Facial injection of hyaluronic acid-based dermal fillers.
- Where
- 8 sites in France
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Symatese
Skin Aging
Study on Safety and Efficacy of Monopolar Radio Frequency Device for Facial Skin Tightening
Objective: The goal of this clinical trial is to evaluate the safety and efficacy of the VOLNEWMER monopolar radiofrequency device developed by CLASSYS Inc.
- Trial name
- NCT06816069
- Testing
- VOLNEWMER
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Photoaging, Weight Loss
Evaluation of the Effects of a Biostimulator and Dermal Fillers for Cheek Augmentation and Contour Deficiencies
Adult subjects with a history of or currently taking glucagon-like peptide-1 (GLP-1) receptor agonist medication and moderate-to-severe cheek wrinkles and midface contour deficiencies will be treated with Sculptra correction of…
- Conditions
- Photoaging, Weight Loss, Skin Laxity, Photodamaged Skin
- Trial name
- NCT06351358
- Testing
- Sculptra treatment, Restylane Treatment
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Anesthesia
Experimental Pain Study to Assess Local Anesthetic Efficacy and Safety of CTY-5339 Anesthetic Spray in Normal Volunteers
The purpose of this study is to determine if the topical application to cheek tissue of the combination of benzocaine and tetracaine has a longer duration of local anesthetic activity than benzocaine alone.
- Trial name
- NCT02908620
- Testing
- One spray CTY-5339-A, One spray CTY-5339-CB, Two sprays CTY-5339-A
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cetylite Industries
Wrinkle, Aging
Evaluation of Performance and Safety of INNEA and INNEA AQUA for the Treatment of Cheek and décolletage Wrinkles
A Post-Market, Single-arm, Confirmatory Interventional Clinical Investigation to evaluate the Performance and Safety of INNEA and INNEA AQUA for the treatment of cheek and décolletage wrinkles
- Trial name
- NCT07331181
- Testing
- Innea, Innea Aqua
- Where
- 3 sites in Italy
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Innate srl
Cheek Volume Augmentation
A Prospective, Multicenter, Randomized, Comparator-controlled, Evaluator-blinded Study to Evaluate the Safety and Effectiveness of VP1 Lido US for Volume Augmentation of the Cheek
The primary objective of the study is to demonstrate non-inferiority of VP1 Lido US versus an approved hyaluronic acid dermal filler following deep (subdermal and/or supraperiosteal) injection of the cheek for volume augmentation.
- Trial name
- BCheek (NCT04886232)
- Testing
- VP1 Lido US, Restylane Lyft Lidocaine
- Where
- 10 sites in Germany
- Volunteers
- 202 people
- Sponsor
- Merz North America, Inc.
Cheek Augmentation
GAL1704 for Cheek Augmentation and Correction of Midface Contour Deficiencies
An interventional study to evaluate the safety and effectiveness of GAL1704 for cheek augmentation and the correction of midface volume deficiencies by demonstrating non-inferiority in change from baseline, relative to an active…
- Trial name
- NCT03700047
- Testing
- GAL1704, Juvederm Voluma
- Where
- 15 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Angiofibroma of Face, Tuberous Sclerosis
Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex
The objective of this study is to evaluate the safety and efficacy of sirolimus (0.2% and 0.4% formulations) and its vehicle when applied topically once daily for 12 weeks for the treatment of cutaneous angiofibromas in pediatric…
- Trial name
- NCT03363763
- Testing
- Sirolimus 0.2%, Sirolimus 0.4%
- Where
- 8 sites in United States, China
- Volunteers
- 24 people
- Sponsor
- Aucta Pharmaceuticals, Inc
Plaque, Dental
Anti-bacterial Clinical Study on Teeth, Tongue, Cheek, Gum, and Saliva
This 4-week clinical study was designed to examine the antibacterial efficacy of brushing with a 0.454% stannous fluoride toothpaste with potassium nitrate and pyrophosphate compared to a toothpaste containing 0.76% MFP (marketed…
- Trial name
- NCT06353165
- Testing
- Stannous fluoride toothpaste, Colgate Dental Cream
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Lung Cancer
Rapid Absorbance-based Detection of Inner Cheek Cell Abnormalities Using Light Spectroscopy for Risk Evaluation of Lung Cancer to Enable Critical Decision Support in Targeted Patient Populations
Overview Sierra Medical is at the forefront of early detection of lung cancer by creating AIR-DS, a non-invasive early detection test.
- Trial name
- RADICAL-REACT (NCT07051044)
- Testing
- AIR-DS
- Where
- 2 sites in United Kingdom
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Sierra Medical Ltd.
Wrinkles
Single-Blind, Investigational Device Exemption Paired-Design, Non-Inferiority Trial With Confirmation for the Assessment of the Efficacy and Safety of a Universal Electrosurgical Device for Temporary Improvement of Mild and Moderate Wrinkles Around Both Eye Corners and Both Cheek Folds
Radiofrequency (RF) devices are commonly used for noninvasive facial rejuvenation. This study compared the efficacy and safety of 10THERMA, a newly developed monopolar RF device, with those of the Thermage FLX system.
- Trial name
- NCT07467811
- Testing
- 10THERMA, Thermage FLX
- Where
- 3 sites in South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- TENTECH INC.
Cheek Augmentation, Midface Contour Deficiencies
Injection Technique Assessment of Restylane Lyft With Lidocaine for Cheek Augmentation
This is a multi-center, open-label, single-arm study to evaluate an injection tool with Restylane Lyft with Lidocaine for cheek augmentation and correction of age related midface contour deficiencies.
- Trial name
- NCT03160716
- Testing
- Restylane Lyft with Lidocaine
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Cheek Wrinkles
Safety and Effectiveness of Sculptra Aesthetic for Correction of Cheek Wrinkles
The study has been designed to evaluate the safety and effectiveness of Sculptra Aesthetic as a single regimen for correction of cheek wrinkles after changes in reconstitution and injection procedures compared to the approved…
- Trial name
- NCT04124692
- Testing
- Sculptra Aesthetic new dilution
- Where
- 13 sites in United States
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Signs of Facial Aging With Volume Loss in the Upper Cheeks, Nasolabial Folds and Marionette Lines
Safety, Effectiveness and Participant Satisfaction Study of a Dermal Filler (of RADIESSE® (+) Lidocaine) in the Treatment of Ageing Signs in the Face
The primary objective is to collect clinical data to confirm performance and safety for RADIESSE® (+) Lidocaine, when used in accordance with its labelling in the treatment of nasolabial folds, marionette lines and/or upper cheek…
- Trial name
- RaLido (NCT03650387)
- Testing
- RADIESSE® (+) Lidocaine
- Where
- 7 sites in Germany
- Volunteers
- 207 people
- Sponsor
- Merz North America, Inc.
Cheek Wrinkles, Midface Contour Deficiencies
Safety and Effectiveness of GP0112 for Cheek Augmentation and Correction
A prospective, randomized, evaluator-blinded, comparator-controlled, parallel group, multicenter study to evaluate the safety and effectiveness of GP0112 for cheek augmentation and correction of midface contour deficiencies
- Trial name
- NCT05098457
- Testing
- GP0112, Restylane Lyft Lidocaine
- Where
- 8 sites in Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Galderma R&D
Skin Aging, Cheek Wrinkles
TCRM for Correction of Cheek Including Fine Lines
The purpose of this clinical study is to evaluate benefits and risks of injecting TCRM in the cheek including fine lines. The goal is to show that treatment with TCRM will result in correcting the cheek area including the fine…
- Trial name
- NCT07145905
- Testing
- TCRM
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Facial Tissue Augmentation
A Study of Treatment Preference During Cheek Contouring Comparing Restylane® SubQ With and Without the Addition of Lidocaine Hydrochloride
The objectives of this study are to evaluate the pain-relieving effect and safety of adding lidocaine hydrochloride to Restylane SubQ and to evaluate the esthetic improvement obtained.
- Trial name
- NCT01431755
- Testing
- Restylane SubQ, Restylane SubQ Lidocaine
- Where
- 3 sites in Sweden
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Dermal Fillers, Cheek Augmentation
Evaluation of Performance and Safety of Injectable KIO017 Device Range for Facial Tissue Filling
The goal of this clinical trial is to primarily evaluate the performance of KIO017 in filling/volumizing after injection in different areas in healthy women or men, older than 18 years and seeking an improvement of her/his face…
- Conditions
- Dermal Fillers, Cheek Augmentation, Lip Augmentation, Perioral Rhytids
- Trial name
- LITCHEE (NCT06872359)
- Testing
- KIO017-1, KIO017-2, KIO017-3
- Where
- 3 sites in France, Poland
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Kiomed Pharma
Skin Smoothness of the Cheeks
JUVÉDERM® VOLITE™ XC for Cheek Skin Smoothness
This is a pivotal study to collect safety and effectiveness data on JUVÉDERM VOLITE™ XC for improvement in skin smoothness of the cheeks in order to support FDA product approval.
- Trial name
- NCT03728309
- Testing
- JUVÉDERM VOLITE™ XC
- Where
- 14 sites in United States, Puerto Rico
- Volunteers
- 209 people
- Sponsor
- Allergan
Cheek Wrinkles, Midface Contour Deficiencies
Safety and Effectiveness of GP0112 for Cheek Augmentation and Correction of Midface Contour Deficiencies
A randomized, evaluator-blinded, parallel group, comparator-controlled, multicenter study to evaluate the safety and effectiveness of GP0112 for cheek augmentation and correction of midface contour deficiencies
- Trial name
- NCT05262777
- Testing
- GP0112, Restylane Lyft Lidocaine
- Where
- 15 sites in Canada
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Galderma R&D