Clinical trials: Chemotherapy Induced Pain
Post-operative Pain, Acute, Cesarean Section
Management of Postoperative Pain After Cesarean Delivery Using Bridge Auricular Percutaneous Nerve Field Stimulator
Post-cesarean section (CS) pain is commonly treated with acetaminophen, ibuprofen, and opioid medications as needed following delivery.
- Conditions
- Post-operative Pain, Acute, Cesarean Section, Opioid Use Disorder, Opioids; Harmful Use
- Trial name
- NCT06434714
- Testing
- Auricular percutaneous nerve field stimulator
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Inova Health Care Services
Chemotherapy-Induced Peripheral Neuropathy, Radiation Toxicity
Patients Referred to the Chronic Pain Unit for Palliative Treatment With Ozone Therapy Between 2026 and 2029.
The main objective of this study is to analyze the impact on the health-related quality of life of patients with refractory symptoms who have been referred to the Dr.
- Conditions
- Chemotherapy-Induced Peripheral Neuropathy, Radiation Toxicity, Chronic Pain, Delayed Wound Healing
- Trial name
- EPOOzo-2 (NCT07325851)
- Testing
- Ozone Therapy
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Bernardino Clavo, MD, PhD
Pain, Mucositis
Topical Morphine for Stomatitis-related Pain Induced by Chemotherapy
Stomatitis/oral mucositis is a common side effect to chemotherapy. Stomatitis is often associated with painful ulcers in the mouth.
- Trial name
- NCT00357942
- Testing
- morphine solution for injection, morphine mouthwash
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Danish University of Pharmaceutical Sciences
Neoplasms, Child
VR to Improve CINV, Sleep and Pain Among Children With Cancer in HK
Chemotherapy-induced nausea and vomiting, sleep quality and pain are the common symptoms experienced by children with cancer. These symptoms significantly devastate the children's quality of life.
- Conditions
- Neoplasms, Child, Nausea, Vomiting
- Trial name
- NCT04853303
- Testing
- Hypnosis VR
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Chemotherapy-induced Peripheral Neuropathy, Nerve Pain
The Effect of Yoga on Nerve Pain Caused by Chemotherapy (Chemotherapy-Induced Peripheral Neuropathy)
The purpose of this study is to test whether yoga can reduce nerve pain caused by cancer treatment (chemotherapy-induced peripheral neuropathy, or CIPN).
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Nerve Pain, Neuropathy, Neuropathy, Painful
- Trial name
- YCT (NCT05121558)
- Testing
- Yoga, Education control, Usual care
- Where
- 8 sites in United States
- Volunteers
- 227 people
- Sponsor
- Dana-Farber Cancer Institute
Peripheral Neuropathy Due to Chemotherapy
Exploring the Benefit of Topical Capsaicin in Treating Pain From Chemo-induced Peripheral Neuropathy: a Longitudinal Single Center Pilot Study
To learn if topical capsaicin can help relieve pain from CIPN and improve gait (the pattern of walking) in patients.
- Trial name
- NCT06744816
- Testing
- Qutenza Patch
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer, Colorectal Cancer
Chemotherapy-Induced Peripheral Neuropathy Survey
The goal of this research study is to learn more about pain and other symptoms that patients may experience while receiving chemotherapy treatment with platinum agents, taxanes, and/or bortezomib.
- Conditions
- Breast Cancer, Colorectal Cancer, Myeloma, Chemotherapy-induced Peripheral Neuropathy
- Trial name
- NCT01016028
- Testing
- Questionnaire, Sensory Tests, Interview
- Sponsor
- M.D. Anderson Cancer Center
Chemotherapy-induced Neuropathy
Characterization and Treatment of Chemotherapy Neuropathy
Numbness, tingling, and pain in the hands and feet following the administration of chemotherapy (also called chemotherapy-induced neuropathy (CIN)) is a common problem in oncology patients.
- Trial name
- CIN (NCT01557608)
- Testing
- Photon stimulation
- Where
- United States
- Volunteers
- 754 people
- Sponsor
- University of California, San Francisco
Cancer Survivor, Pain
Somatic Yoga and Meditation for Cancer Survivors With Pain From Neuropathy
Chemotherapy-induced peripheral neuropathy syndrome (CIPN) causes significant pain in hands and feet and is an adverse effect of treatment.
- Conditions
- Cancer Survivor, Pain, Chemotherapy Induced Peripheral Neuropathy, Function
- Trial name
- Y4CIPN (NCT03786055)
- Testing
- Somatic Yoga and Meditation (SYM)
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Stockton University
Neuropathic Pain
Sativex for Treatment of Chemotherapy Induced Neuropathic Pain
Chemotherapy is often used to treat cancer and in many cases can cure it or extend life. Unfortunately many of the chemotherapeutic agents used in treating cancer can cause nerve damage, resulting in severe pain involving the…
- Trial name
- NCT00872144
- Testing
- Sativex
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Mary Lynch
Cancer, Mucositis
Effect of Topical Morphine (Mouthwash) on Oral Pain Due to Chemo- and/or Radiotherapy Induced Mucositis
Introduction: Oral pain due to mucosal lesion is quite frequent in oncology, geriatric as well as palliative care settings. The oncology patient is mainly suffering from radio- and/or chemotherapy induced oral mucositis.
- Trial name
- NCT00613743
- Testing
- mouth wash with morphine
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Hospital, Geneva
Qutenza, Duloxetine
Qutenza Versus Duloxetine in Chemotherapy-induced Peripheral Neuropathy (CIPN)
The primary objective is to determine whether in patients with CIPN pain, treatment with Qutenza has the same effect as treatment with duloxetine 60 mg daily.
- Conditions
- Qutenza, Duloxetine, Chemotherapy-induced Peripheral Neuropathy, CIPN - Chemotherapy-Induced Peripheral Neuropathy
- Trial name
- QULOX (NCT05560516)
- Testing
- Qutenza, Duloxetine
- Where
- Netherlands
- Volunteers
- 102 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Peripheral Neuropathy
Innovative Treatment of Chemotherapy-Induced Painful Peripheral Neuropathy in Adolescents and Young Adults With Cancer: A Two Arm Pilot Study
To evaluate the efficacy and safety of Scrambler therapy (ST) for chemotherapy-induced painful peripheral neuropathy (CIPN), and the impact of ST on physical functioning and quality of life (QoL) in adolescents and young adults…
- Trial name
- NCT05357469
- Testing
- Immediate St (Scrambler Therapy), Waitlist ST (Scrambler Therapy)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Peripheral Nerve Stimulation, Chemotherapy-induced Peripheral Neuropathy
Exploring the Benefit of Peripheral Nerve Stimulation in Treating Pain From Chemo-induced Peripheral Neuropathy: A Longitudinal Single Center Feasibility Study
To learn if peripheral nerve stimulation (PNS) can help to improve pain in participants with CIPN.
- Trial name
- NCT06162403
- Testing
- Peripheral Nerve Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- M.D. Anderson Cancer Center
Chemotherapy-induced Peripheral Neuropathy (CIPN)
Auricular Point Acupressure: Examining the Scientific Underpinnings of Pain Relief
Chemotherapy-induced peripheral neuropathy (CIPN)-numbness, burning and stunning pain distributed in hands and feet-is a major challenge among cancer patients.
- Trial name
- NCT03634527
- Testing
- Auricular Point Acupressure, Control Auricular Point Acupressure-
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Johns Hopkins University
Chemotherapy-induced Peripheral Neuropathy (CIPN)
Topical Herbal Medicine for Chemotherapy-Induced Peripheral Neuropathy
The goal of this clinical trial is to learn if menthol works to relieve chronic neuropathic pain and chemotherapy-induced peripheral neuropathy (CIPN).
- Trial name
- NCT07693387
- Testing
- menthol-based hand and foot gloves
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taiwan Municipal An-Nan Hospital-China Medical University
Breast Carcinoma
Topical Cryotherapy in Reducing Pain in Patients With Chemotherapy Induced Peripheral Neuropathy or Paclitaxel Induced Acute Pain Syndrome
This randomized pilot clinical trial studies topical cryotherapy (cooling hands and feet with ice bags) in reducing pain in patients with chemotherapy induced peripheral neuropathy or paclitaxel induced acute pain syndrome.
- Trial name
- NCT02640053
- Testing
- Cryotherapy, Paclitaxel, Quality-of-Life Assessment
- Where
- 8 sites in United States
- Volunteers
- 46 people
- Sponsor
- Academic and Community Cancer Research United
Oral Mucositis, Oral Stomatitis
Ozone Therapy for Oral Mucositis in Patients Receiving Head and Neck Cancer Radio- and Chemotherapy
Oral mucositis is a frequent and painful side effect of radio- and chemotherapy, especially in patients with head and neck cancer.
- Conditions
- Oral Mucositis, Oral Stomatitis, Head and Neck Cancer Squamous Cell Carcinoma, Radiotherapy Induced Mucositis
- Trial name
- OZOMUC (NCT07199712)
- Testing
- Ozone Therapy (In-Office and Home-Based Treatment)
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- University of Pavia
Diabetic Neuropathies, Complex Regional Pain Syndrome Type II
The Effect of Transcranial Direct Current Stimulation (t-DCS) On the P300 Component of Event-Related Potentials in Patients With Chronic Neuropathic Pain Due To CRPS or Diabetic Neuropathy
This is a controlled trial designed to determine short- and long-term effects of repeated tDCS on the P300 component of event-related evoked potentials in patients with chronic neuropathic pain due to Complex regional Pain…
- Conditions
- Diabetic Neuropathies, Complex Regional Pain Syndrome Type II, Resistant Peripheral Neuropathic Pain, Chemotherapy Induced Pain Neuropathy
- Trial name
- NCT00815932
- Where
- Israel
- Sponsor
- Soroka University Medical Center
Chemotherapy-induced Peripheral Neuropathy, Pain
Transcutaneous Electrical Nerve Stimulation (TENS) for Chemotherapy Induced Peripheral Neuropathy (CIPN)
The purpose of this pilot study is to examine the acceptability and proof of concept effectiveness of a wireless Transcutaneous Electrical Nerve Stimulation (TENS) technology to address Chemotherapy Induced Peripheral Neuropathy…
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Pain, Neuropathy
- Trial name
- NCT06324344
- Testing
- High-Dose TENS, Low-Dose TENS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Baylor College of Medicine