Clinical trials: Chemotherapy Induced Peripheral Neuropathy
Chemotherapy-induced Peripheral Neuropathy
Clinical Biomarker of Paclitaxel-induced Peripheral Neuropathy
Investigation of which patients treated with paclitaxel have an increased risk of developing peripheral neuropathy.
- Trial name
- NCT06430814
- Testing
- No intervention
- Where
- 3 sites in Denmark
- Volunteers
- 188 people
- Sponsor
- University of Southern Denmark
Peripheral Neuropathy Due to Chemotherapy
Prevention of Paclitaxel-induced Peripheral Neuropathy in Breast Cancer Patients
Paclitaxel-induced peripheral neuropathy (PIPN) is one of the most dose-limiting side effects; it causes patients discomfort and pain and sometimes causes the termination of the chemotherapy cycles, leading to treatment failure.
- Trial name
- NCT06135493
- Testing
- Losartan
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Future University in Egypt
Chemotherapy Induced Peripheral Neuropathy (CIPN)
SUNCIST: A Study of Calmangafodipir in Healthy Japanese and Caucasian Subjects
Randomized, double-bline, placebo-controlled, single dose study comparing the pharmacokinetics (PK) and safety of PP095-01 in Japanese and non-Asian (eg, Caucasian) subjects.
- Trial name
- NCT03430999
- Testing
- Calmangafodipir
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Egetis Therapeutics AB (publ)
Neurotoxicity, Pain
Gabapentin in Treating Peripheral Neuropathy in Cancer Patients Undergoing Chemotherapy
RATIONALE: Gabapentin may be effective in relieving pain and other symptoms of peripheral neuropathy. It is not yet known if gabapentin is effective in treating peripheral neuropathy in cancer patients undergoing chemotherapy.
- Trial name
- NCT00027963
- Testing
- gabapentin
- Where
- 23 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Pain, Neuropathic Pain
Evaluate The Efficacy and Safety Of Pregabalin In Prevention, Reduction of Oxaliplatin-Induced Painful Neuropathy
Oxaliplatin (Ox) is part of most treatment regimens for colorectal cancer. However, it may induce side effects, such as a specific injury to peripheral nerves called neuropathy. Ox-induced neuropathy is frequently painful.
- Conditions
- Pain, Neuropathic Pain, Polyneuropathy
- Trial name
- PreOx (NCT01450163)
- Testing
- Pregabalin, Oxaliplatin
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo
Neuropathy;Peripheral
Exploring the Benefit of Neuromodulation in Treating Chemo-induced Peripheral Neuropathy Using Peripheral Neuropathy Markers (Meissner's Corpuscles and Epidermal Nerve Fiber Density) and Sensory Testing (Quantitative Sensory and Gait Testing): A Single Center Feasibility Study
To learn if a process called neuromodulation can help to improve pain due to CIP
- Trial name
- NCT06121232
- Testing
- Abbott® DRG / Abbott®/Medtronic® SCS, Control Group
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- M.D. Anderson Cancer Center
CIPN - Chemotherapy-Induced Peripheral Neuropathy, Gastrointestinal Cancers
TENS and Compression for Established Oxaliplatin-Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy is a clinically important adverse effect of oxaliplatin-based chemotherapy that may cause sensory symptoms, neuropathic pain, functional limitations, and reduced quality of life.
- Trial name
- NCT07409987
- Testing
- TENS, Compression Garments, Sequential TENS Plus Compression
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Cumhuriyet University