Clinical trials: Chemotherapy Induced Peripheral Neuropathy (CIPN)
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Assessing Functional Impairments in Patients With Chemotherapy-Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a severe side effect of several anti-cancer agents. Typical symptoms include tingling and hypoesthesia in the fingertips and/or toes, which substantially impair patients'…
- Trial name
- Assess CIPN (NCT07315334)
- Testing
- Questionnaire and Physical Exam
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Paracelsus Medical University
Chemotherapy-induced Peripheral Neuropathy
Diagnostic of Chemotherapy Induced Neuropathy in Children
The purpose of this study is to determine the diagnostic accuracy of a newly developed tool (Electrochemical Skin Conductances (ESC) measurement) easy-to-perform, non-invasive, highly reproductible and not requiring specific…
- Trial name
- SUDOPED (NCT04262778)
- Testing
- electrochemical skin conductance measurement
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cancer, Chemotherapy-induced Peripheral Neuropathy (CIPN)
Electroacupuncture and Exercise for Chemotherapy-Induced Peripheral Neuropathy (CIPN)
Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of cancer treatment that causes numbness, pain, and balance issues in a patient's hands and feet.
- Trial name
- EA-EX CIPN (NCT07700901)
- Testing
- Electroacupuncture, Exercise Training, Structured Home-Based Health Education and Dose-Controlled Exercise Program
- Where
- 2 sites in Taiwan
- Volunteers
- 82 people
- Sponsor
- Show Chwan Memorial Hospital
Painful Peripheral Neuropathy, Diabetic Peripheral Neuropathic Pain (DPN)
SPENDD: Quantitative Sensory Testing and Analgesic Response for Painful Peripheral Neuropathy.
The goal of this clinical trial is to determine whether quantitative sensory testing (QST) can be used to classify participants into pain sub-groups and predict who will respond best to certain pain treatments in participants…
- Conditions
- Painful Peripheral Neuropathy, Diabetic Peripheral Neuropathic Pain (DPN), Chemotherapy Induced Peripheral Neuropathy (CIPN), Idiopathic Peripheral Neuropathy
- Trial name
- NCT06614322
- Testing
- Pregabalin, Duloxetine
- Where
- 7 sites in United States
- Volunteers
- 190 people
- Sponsor
- University of Rochester
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Stibium Metallicum Praeparatum D6 Versus Placebo in the Reduction of Paclitaxel-induced Peripheral Neurotoxicity
Chemotherapy induced peripheral neuropathy (CIPN) is one of the most limiting side effects of chemotherapy and often leads to adaptations in the protocol of the chemotherapy including dose reduction or even discontinuation of…
- Trial name
- STING-CIPN (NCT04715542)
- Testing
- Stibium metallicum praeparatum 6x
- Volunteers
- 86 people
- Sponsor
- University of Bern
CIPN
Sensory Rehabilitation in Chemotherapy Induced Peripheral Neuropathy (CIPN)
Physiotherapist research about Sensory rehabilitation in chemotherapy induced peripheral neuropathy (CIPN) with the aid of questioners and physiotherapy practice
- Trial name
- NCT05382520
- Testing
- Questionares and practice
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Assaf-Harofeh Medical Center
Chemotherapy-induced Peripheral Neuropathy
Acupuncture for Chemo-Induced Peripheral Neuropathy in Multiple Myeloma Patients
This randomized, controlled trial is designed to evaluate the effect of acupuncture on Chemotherapy-Induced Peripheral Neuropathy (CIPN), other symptoms, and potential opioid and concomitant medication sparing effects in…
- Trial name
- NCT04770402
- Testing
- Acupuncture, Standard of Care CIPN management
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Wake Forest University Health Sciences
CIPN - Chemotherapy-Induced Peripheral Neuropathy, Gastrointestinal Cancers
TENS and Compression for Established Oxaliplatin-Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy is a clinically important adverse effect of oxaliplatin-based chemotherapy that may cause sensory symptoms, neuropathic pain, functional limitations, and reduced quality of life.
- Trial name
- NCT07409987
- Testing
- TENS, Compression Garments, Sequential TENS Plus Compression
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Cumhuriyet University
CIPN - Chemotherapy-Induced Peripheral Neuropathy
Effects of an Exercise Intervention on Taxane-induced Peripheral Neuropathy in Breast Cancer Survivors
The purpose of this study is to examine the effects of an exercise program on the management of TIPN in breast cancer survivors.
- Trial name
- NCT05641571
- Testing
- The home-based extremity exercise program
- Volunteers
- 88 people
- Sponsor
- Taichung Veterans General Hospital
Peripheral Neuropathy
Effects of Reiki, Yoga, Meditation, on the Physical and Psychological Symptoms of Chemotherapy-Induced Peripheral Neuropathy
The purpose of this study is to test whether people with symptoms of chemotherapy-induced peripheral neuropathy (CIPN) receive physical or psychological benefits from participating in a six-week Reiki, Yoga, Meditation, or…
- Trial name
- NCT01569269
- Testing
- Yoga Intervention, Meditation Intervention, Reiki
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- George Mason University
Peripheral Neuropathy
Acupuncture in Chemotherapy-induced Peripheral Neuropathy in Women With Breast Cancer
The main purpose of this study is to define whether acupuncture in addition to the treatment of physician choice as per standard of care leads to a greater decrease of neuropathic pain as perceived by women with breast cancer who…
- Trial name
- Acu-CIPN (NCT05673746)
- Testing
- Acupuncture, treatment of physician choice, according to the standard of care
- Where
- 2 sites in Italy
- Volunteers
- 102 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Chemotherapy-Induced Peripheral Neuropathy, Hematopoietic and Lymphoid Cell Neoplasm
Testing the Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy
This phase II trial studies whether using exercise is better than the usual approach for treating chemotherapy-induced peripheral neuropathy (CIPN).
- Conditions
- Chemotherapy-Induced Peripheral Neuropathy, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- CIPN (NCT04888988)
- Testing
- Best Practice, Exercise Counseling, Exercise Intervention
- Where
- 93 sites in United States
- Volunteers
- 133 people
- Sponsor
- University of Rochester NCORP Research Base
Chemotherapy-induced Peripheral Neuropathy
Cannabidiol for Prevention of Chemotherapy-induced Peripheral Neuropathy
This protocol describes a phase II trial investigating the efficacy of CBD in paclitaxel- and oxaliplatin-induced peripheral neuropathy.
- Trial name
- CINCAN-2 (NCT04582591)
- Testing
- Cannabidiol 100 MG/ML
- Where
- Denmark
- Volunteers
- 54 people
- Sponsor
- Zealand University Hospital
Breast Cancer, Peripheral Neuropathies
Chemotherapy-Induced Peripheral Neuropathy-Essential Oil Intervention
This study will evaluate an oil blend with active ingredients for the reduction in chemotherapy-induced peripheral neuropathy in people with breast cancer.
- Trial name
- CIPN-EOI (NCT03449303)
- Testing
- EOI
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Augusta University
Chemotherapy
A Stuty on the Treatment and Nursing Care of CIPN Patients With Traditional Chinese Medicine Hot Package
The combination of platinum and taxane drugs has a chemotherapy-induced peripheral neuropathy (CIPN) rate of 73% to 83%. Its symptoms can not only limit daily activities and cause a variety of accidental injuries, but also easily…
- Trial name
- NCT06492083
- Testing
- traditional Chinese medicine hot bag
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Patients With Solid Tumors
Traditional Chinese Medicine Hand-Foot Soak for Chemotherapy-Induced Peripheral Neuropathy and Hand-Foot Syndrome
Systemic therapies, including chemotherapy, targeted therapy, and immunotherapy, are cornerstones of modern oncology and have significantly extended patient survival.
- Trial name
- NCT07375446
- Testing
- Traditional Chinese Medicine
- Volunteers
- 300 people
- Sponsor
- Peking University Third Hospital
Chemotherapy-induced Peripheral Neuropathy (CIPN)
Auricular Point Acupressure: Examining the Scientific Underpinnings of Pain Relief
Chemotherapy-induced peripheral neuropathy (CIPN)-numbness, burning and stunning pain distributed in hands and feet-is a major challenge among cancer patients.
- Trial name
- NCT03634527
- Testing
- Auricular Point Acupressure, Control Auricular Point Acupressure-
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Johns Hopkins University
Chemotherapy-induced Peripheral Neuropathy (CIPN)
Effectiveness of Video-Based Movement Analysis-Guided Personalized Rehabilitation in Patients With Chemotherapy-Induced Peripheral Neuropathy (CIPN)
This study aims to quantify motor control abnormalities using video-based movement analysis in patients with chemotherapy-induced peripheral neuropathy (CIPN) and to evaluate the effectiveness of an analysis-guided personalized…
- Trial name
- NCT07714278
- Testing
- ReMap, Usual Care
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Bundang Hospital
CIPN - Chemotherapy-Induced Peripheral Neuropathy
Study to Investigate the Chemotherapy-Induced Peripheral Neuropathy (CIPN) Onset-Suppressing Effect and Safety of ONO-2910 in Patients With Breast Cancer Receiving Weekly Paclitaxel
To investigate the safety and CIPN onset-suppressing effect of ONO-2910 in participants receiving paclitaxel (PTX) weekly as chemotherapy for breast cancer in Japan.
- Trial name
- NCT06538272
- Testing
- ONO-2910
- Where
- 30 sites in Japan
- Volunteers
- 210 people
- Sponsor
- Ono Pharmaceutical Co., Ltd.
Chemotherapy-Induced Peripheral Neuropathy (CIPN)
Heat and Cold Therapy for Chemotherapy-Induced Neuropathy
Cancer patients undergoing chemotherapy experience various side effects depending on the treatment protocol used. Chemotherapy-Induced Peripheral Neuropathy (CIPN) is a dose-limiting and quality-of-life-reducing complication…
- Trial name
- NCT06889129
- Testing
- Experimental- Heat application, Experimental-Cold application
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Bilecik Seyh Edebali Universitesi