Clinical trials: Chemotherapy Side Effects
Chemo-brain, Drug-Related Side Effects and Adverse Reactions
Acupuncture Prevents Chemobrain in Breast Cancer Patients
Chemobrain is an expression used to describe a cluster of chemotherapy-induced cognitive impairment symptoms, including problems with visual and verbal memory, forgetfulness, difficulty in learning, attention, concentration and…
- Conditions
- Chemo-brain, Drug-Related Side Effects and Adverse Reactions, Mild Cognitive Impairment, Breast Cancer
- Trial name
- NCT02457039
- Testing
- Dense cranial electroacupuncture stimulation, Body acupuncture, Least acupuncture stimulation
- Where
- 6 sites in China, Hong Kong
- Volunteers
- 93 people
- Sponsor
- The University of Hong Kong
Exploration of How Patients Deal With Side Effects From Chemotherapy
A Qualitative Study Into How Patients Deal With Chemotherapy-related Side Effects at Home
This qualitative study explores how patients deal with the side effects from chemotherapy at their home, what factors and ideas influence their symptom self-management and how professional caregivers contribute to the management…
- Trial name
- NCT01867489
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 28 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Hearing Loss
Transtympanic Ringer's Lactate for the Prevention of Cisplatin Ototoxicity
Cisplatin and carboplatin induce ototoxicity manifested as sensorineural hearing loss, tinnitus, and/or vestibular disturbances. Ototoxicity is induced via damage to inner ear structures by reactive oxygen species.
- Trial name
- NCT01108601
- Testing
- Ringer's Lactate (0.03% Ciprofloxacin)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Ovarian Carcinoma, Survival Outcomes
Niraparib Plus Anlotinib for Recurrent Ovarian Cancer
This is a phase II trial to explore efficacy and safety of niraparib in combination with anlotinib based on CA 125 level in newly diagnosed ovarian cancer.
- Conditions
- Ovarian Carcinoma, Survival Outcomes, Adverse Events, Niraparib
- Trial name
- NCT05311579
- Testing
- Niraparib plus anlotinib
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Lei Li
Breast Cancer
A Prospective Observational Study About Adjuvant or Neoadjuvant Chemotherapy Related Adverse Effects in Premenopausal Breast Cancer Patients
Breast cancer is one of the most common malignant tumor in women. About 60% of breast cancer patients are still in premenopausal status at the time of diagnosis in China. It is a multicenter prospective observational study.
- Trial name
- NCT03543059
- Testing
- GnRH analogue
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Sun Yat-sen University
Vitamin D, Chemotherapy
Effect of Vitamin D Supplementation on Chemotherapy Side Effects After Adjuvant Chemotherapy for Breast Cancer
This randomized controlled Phase III trial was designed to evaluate the effect of vitamin D supplementation (VD) on chemotherapy side effects following adjuvant chemotherapy in breast cancer
- Conditions
- Vitamin D, Chemotherapy, Breast Cancer, Adverse Reaction
- Trial name
- NCT06642441
- Testing
- Chemotherapy + vitamin D2, Chemotherapy
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- Jiuda Zhao
Breast Cancer
Effects of Short-term Fasting on Tolerance to Chemotherapy
The purpose of this study is to determine the effect of short-term fasting on tolerance to adjuvant chemotherapy in breast cancer patients
- Trial name
- NCT01304251
- Testing
- Short-term fasting, Healthy nutrition
- Where
- Netherlands
- Volunteers
- 13 people
- Sponsor
- Leiden University Medical Center
Breast Cancer
Pilot Study of a MIND Diet Intervention in Women Undergoing Active Treatment for Breast Cancer
Breast cancer (BC) is the most frequently diagnosed cancer in women. Systemic cancer treatments are an important contributor to dramatic improvements in the long-term survival of women with BC.
- Trial name
- MIND-BC (NCT05984888)
- Testing
- MIND Diet Intervention Group, General Health Curriculum (GHC) Group
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Febrile Neutropenia, Solid Tumor
Shared Health Information System for Febrile Neutropenia
The use of e-health in improving the quality of health services is a rapidly expanding research area, in particular its usefulness in patient management of the home-hospital care pathway.
- Conditions
- Febrile Neutropenia, Solid Tumor, Hematologic Neoplasms
- Trial name
- NEUTROSIS (NCT03087227)
- Testing
- NEUTROSIS
- Where
- 3 sites in France
- Volunteers
- 121 people
- Sponsor
- Marie-Helene METZGER
Non Hodgkin Lymphoma, DLBCL
Cardiotoxicity and Other Late Effects After Radiotherapy and Immuno-chemoTherapy in Non-Hodgkin lYmphoma
Survivors of non-Hodgkin lymphoma and a control group will be screened for (sub)clinical cardiovascular disease, to assess the influence of contemporary treatments on risk and burden of (sub)clinical cardiovascular disease and…
- Conditions
- Non Hodgkin Lymphoma, DLBCL, Cardiovascular Diseases, Cardiomyopathies
- Trial name
- CLARITY (NCT07041827)
- Testing
- Cardiovascular assessment
- Where
- Netherlands
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- The Netherlands Cancer Institute
Breast Cancer, Chemotherapy
ALND vs ART in Positive Sentinel Node After Neoadjuvant Therapy in Breast Cancer
In the case of primary surgery, in patients with sentinel node involvement, it has already been shown that omitting axillary lymph node dissection (ALND), often combining axillary radiotherapy (RT), does not worsen the prognosis…
- Conditions
- Breast Cancer, Chemotherapy, Sentinel Lymph Node, Axillary Lymph Nodes Dissection
- Trial name
- ADARNAT (NCT04889924)
- Testing
- Axillary Radiotherapy, Lymphadenectomy
- Where
- 61 sites in Australia, Spain
- Volunteers
- 820 people
- Sponsor
- Hospital Universitari de Bellvitge