Clinical trials: Chemotherapy Training, active
Breast Cancer
Exercise Interventions for Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy
The BENEFIT-Study is a randomized controlled 3-arm intervention trial investigating the currently discussed hypothesis that exercise concomitant to chemotherapy (CTx) may have a beneficial effect on cancer prognosis by boosting…
- Trial name
- BENEFIT (NCT02999074)
- Testing
- Resistance exercise, Aerobic exercise, Usual care during neoadjuvant chemotherapy/Exercise after surgery
- Where
- Germany
- Volunteers
- 183 people
- Sponsor
- German Cancer Research Center
Ovarian Cancer, Ovarian Carcinoma
Exercise as a Preventive Agent to Combat Immobility in Patients With Ovarian or Endometrial Cancers Receiving Chemotherapy
The purpose of this research is to determine whether a 16-week virtually supervised aerobic and resistance exercise program is feasible in patients receiving first-line chemotherapy after surgery for ovarian or endometrial cancer…
- Conditions
- Ovarian Cancer, Ovarian Carcinoma, Ovarian Cancer Stage IV, Ovarian Cancer Stage III
- Trial name
- NCT04997096
- Testing
- Exercise, Attention Control
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dana-Farber Cancer Institute
Acute Lymphoblastic Leukemia
Telematic Cognitive Training and Mindfulness in Pediatric Patients After CAR-T Cell Therapy, Single Hematopoietic Allogeneic Transplant or Chemotherapy
This randomized controlled clinical trial evaluates neurocognitive, biopsychological, and brain connectome outcomes in children and adolescents with acute lymphoblastic leukemia who have previously received Chimeric Antigen…
- Trial name
- PsyCARTkids (NCT07479927)
- Testing
- Digital cognitive training, Online Mindfulness-Based Intervention
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital Universitario La Paz
Breast Cancer
Supervised Aerobic Training During or After Chemotherapy for Operable Breast Cancer
The purpose of this study is to compare the effects of aerobic exercise training during and after chemotherapy for women who have recently been diagnosed with early-stage breast cancer.
- Trial name
- NCT01943695
- Testing
- Aerobic Training, Educational Information, Supervised Home Based Training
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Metastatic Colorectal Cancer (mCRC)
Randomized Controlled Trial of the Effects of Combined Resistance and AerobiC Exercise on Health-related Quality of Life in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer (REACH)
The primary objective of this trial is to compare the effects of 18 weeks structured exercise training versus on control on healt-related quality of life in patients with mCRC undergoing first-line chemotherapy.
- Trial name
- REACH (NCT06938971)
- Testing
- Exercise training
- Where
- 4 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cancer, Breast Cancer
Resistance Training and Post Workout Protein to Improve Body Composition During Neoadjuvant Chemotherapy for Breast Cancer
In this study, the investigators hypothesize that a high dose of post-workout protein nutrition regimen focused on food quality and an observed exercise regimen utilizing high-load resistance training initiated during or after…
- Trial name
- NeoChemoPRT (NCT06858449)
- Testing
- Whey protein (20 grams), Whey protein (60 grams)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Neoplasm Malignant Female
Supervised Exercise During Neoadjuvant Chemotherapy for Breast Cancer
The goal of this clinical trial is to learn whether supervised exercise is practical and safe for women receiving chemotherapy before surgery for breast cancer.
- Trial name
- NCT07764341
- Testing
- Supervised exercise
- Where
- Bahrain
- Volunteers
- 80 people
- Sponsor
- King Hamad University Hospital, Bahrain
Gynecologic Cancer, Chemotherapy Effect
Improve Cancer-related Cognitive Impairment
Cancer-related cognitive impairment (CRCI), also known as "chemobrain," is the cognitive decline that negatively impacts the majority of cancer patients undergoing chemotherapy, radiation, and/or hormonal treatments.
- Conditions
- Gynecologic Cancer, Chemotherapy Effect, Chemo-brain, Cancer-related Cognitive Difficulties
- Trial name
- NCT05864274
- Testing
- Cognitive training application
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Urgency Urinary Incontinence
Behavioral Interventions Versus Pelvic Floor Muscle Therapy as Adjuncts to Anticholinergic Pharmacotherapy for Urgency Urinary Incontinence: A Non-Inferiority Trial
Urgency urinary incontinence (UUI) is a common condition that significantly affects women's quality of life. Pharmacotherapy is often used as first-line treatment, but its effectiveness can be limited unless combined with…
- Trial name
- NI-UUI-2025 (NCT07259148)
- Testing
- Pelvic Floor Muscle Training (PFMT), Behavioral Bladder Training Program, Oxybutynin / Mirabegron (Standardized Pharmacotherapy)
- Where
- Nicaragua
- Volunteers
- 80 people
- Sponsor
- Emilio José Dávila Álvarez
Early Stage Breast Carcinoma, Dyspnea
Inspiratory Muscle Training for Breast Cancer Patients on Chemotherapy
This clinical trial studies whether breathing exercises for the muscles that help with breathing air in, inspiratory muscle training (IMT), works to improve breathing muscle strength, shortness of breath, and physical activity…
- Trial name
- IMACT (NCT07386444)
- Testing
- Inspiratory muscle training
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Breast Cancer
Remotely Supervised Exercise During Chemotherapy in Women With Breast Cancer
The RE-CARE project is designed to evaluate the effects of a 24-week, remotely supervised, combined high-intensity interval aerobic and resistance exercise training on physical health and quality of life in patients with breast…
- Trial name
- NCT07716306
- Testing
- Intervention Group
- Where
- Latvia
- Volunteers
- 60 people
- Sponsor
- Riga Stradins University
Oncology, Cancer-related Cognitive Impairment
Effects of Cognitive Training on Chemotherapy-Induced Cognitive Impairment in Colon Cancer Patients Undergoing Treatment(Chemobrain) in Oncology Patients With Colon Cancer Undergoing Active Treatment
Introduction: With the increasing survival rate in colon cancer, as a result of technological and biomedical advancements, it is essential to thoroughly study the secondary symptoms related to the oncological disease process.
- Conditions
- Oncology, Cancer-related Cognitive Impairment, Cognitive Training, Everyday Cognition
- Trial name
- NCT06710639
- Testing
- Health Education Program, Cognitive Training Program
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Physical Exercise
Effects of a Physical Exercise Intervention During Neoadjuvant Chemotherapy in Women With Breast Cancer
To assess in women with triple-negative breast cancer receiving neo-adjuvant chemotherapy the effects of an intense physical exercise program (intervention group) on physical capacity, compared with a control group not meeting…
- Trial name
- NEOLIFE (NCT04135586)
- Testing
- Exercise training, Control
- Where
- 2 sites in Spain
- Volunteers
- 80 people
- Sponsor
- Universidad Europea de Madrid
Cancer Survivorship, Chemotherapy Side Effects
Remote Physical Activity Programming to Improve Outcomes in Cancer Survivors With and Without Type 2 Diabetes
The growing U.S. cancer survivor population is projected to hit 26M by 2040. Chemotherapy represents an effective cancer treatment but can diminish cancer survivors' quality of life-particularly cognitive function-through select…
- Trial name
- CICI-PA (NCT06725953)
- Testing
- Social Cognitive Theory-based, Technology-delivered Physical Activity Program
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Oklahoma
Chemotherapy Induced Peripheral Neuropathy, Breast Cancer Patients
Effects of Sensorimotor Training With Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer Patients
Chemotherapy-Induced Peripheral Neuropathy (CIPN) is a prevalent and clinically relevant side effect of chemotherapy in breast cancer patients. It occurs in 30-70% of cases. It can cause various sensory and motor symptoms.
- Trial name
- NCT06737926
- Testing
- Sensorimotor Training Exercise, Conventional Exercise Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Breast Cancer
Cognitive Training and Exercise for Women With Breast Cancer and Cognitive Impairment
Chemotherapy-related cognitive impairment is a prevalent and distressing condition among breast cancer survivors, adversely affecting memory, attention, and overall cognitive function, thereby diminishing quality of life.
- Trial name
- CHEMO-CogEx (NCT07017530)
- Testing
- Cognitive training, Psychoeducational therapy
- Where
- Spain
- Volunteers
- 220 people
- Sponsor
- Universidad de Extremadura
Cancer
Remote Mindfulness Breathing Training for Patients Undergoing Chemotherapy
This randomized controlled trial will evaluate the effects of a mobile-delivered remote mindfulness breathing training program on symptom distress, fatigue, anxiety, and depression in adults with cancer who are receiving…
- Trial name
- NCT07806760
- Testing
- Mobile Remote Mindfulness Breathing Training, Brief Mindfulness Breathing Instruction
- Where
- 2 sites in Taiwan
- Volunteers
- 80 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Gastro-esophageal Cancer
Feasibility and Effect of Resistance Training and Protein Supplementation in Patients With Advanced Gastroesophageal Cancer
Patients with advanced gastroesophageal cancer are in great risk of losing skeletal muscle mass and developing cancer cachexia. Low skeletal muscle mass has a negative impact on quality of life, impairs physical function…
- Trial name
- NCT05650827
- Testing
- Resistance training, Protein supplement
- Where
- Denmark
- Volunteers
- 54 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Breast Cancer, Chemotherapy Effect
Improving Cognitive Function Through High-intensity Interval Training in Breast Cancer Patients Undergoing Chemotherapy
The purpose of this research is to determine whether a 16-week high intensity interval training (HIIT) exercise program will improve brain health among women undergoing chemotherapy and also improve cardiovascular (heart)…
- Conditions
- Breast Cancer, Chemotherapy Effect, Exercise Therapy, Cognitive Change
- Trial name
- CLARITY (NCT04724499)
- Testing
- High-Intensity Intervals Training, Attention Control
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dana-Farber Cancer Institute
Head and Neck Neoplasms, Deglutition Disorders
EMST in Patients Undergoing CRT for HNCA
This study is a randomized trial examining the impact of expiratory muscle strength training (EMST) on maintenance of safe and efficient oropharyngeal swallow function in persons with cancer of the head and neck (HNCA) undergoing…
- Trial name
- NCT03916809
- Testing
- EMST
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Wisconsin, Milwaukee