Clinical trials: Chemotherapy-Induced Alopecia
Breast Cancer, Chemotherapy-induced Alopecia
PBMT for the Management of CIA ( HAIRLASER )
Chemotherapy (CT) remains an important treatment modality for breast cancer patients. Unfortunately, this systemic treatment comes with many quality of life impairing complications.
- Conditions
- Breast Cancer, Chemotherapy-induced Alopecia, Alopecia
- Trial name
- NCT04036994
- Testing
- Photobiomodulation therapy
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Hasselt University
Breast Cancer, Hair Loss
Alleviation of Alopecia in Breast Cancer Patient Using Synbiotics Formula
This study aims to explore the efficacy and safety of a synbiotic formula (BLHK03) in alleviating chemotherapy-induced alopecia (CIA) in breast cancer patients and the compositional and functional changes in the gut microbiome of…
- Trial name
- NCT06560385
- Testing
- BLHK03
- Where
- 2 sites in Hong Kong
- Volunteers
- 7 people
- Sponsor
- GenieBiome Limited
Primary Breast Cancer
Comparative Study of Scalp Cooling System and Chemical Cold Cap (COHAIR Study)
This is a phase III, single-center, prospective, open-label, randomized,controlled study
- Trial name
- COHAIR (NCT03711877)
- Testing
- Scalp cooling system, Cold cap
- Where
- China
- Volunteers
- 256 people
- Sponsor
- Tao OUYANG
Chemotherapy Induced Alopecia, Chemotherapy Side Effects
Clinical Study of DA-020 for the Treatment of Chemotherapy Induced Alopecia
Clinical Study of DA-020 as a Treatment for Chemotherapy Induced Alopecia
- Trial name
- NCT07397325
- Testing
- DA-020, DA-020 and Hyperforin
- Where
- 2 sites in Brazil, Italy
- Volunteers
- 60 people
- Sponsor
- Applied Biology, Inc.
Breast Cancer, Chemotherapy-induced Alopecia
Efficacy and Safety of DIGNICAP™ System
Chemotherapy-induced alopecia (CIA) is one of the most common and emotionally distressing side effects of cancer therapy. In this study we sought to assess the feasibility and the effectiveness of scalp cooling system DigniCap®…
- Trial name
- DIGNICAP (NCT03712696)
- Testing
- DIGNICAP™
- Where
- Italy
- Volunteers
- 139 people
- Sponsor
- European Institute of Oncology
Chemotherapy-induced Peripheral Neuropathy (CIPN)
Concomitant Limb Cryocompression and Scalp Cooling to Reduce Paclitaxel-induced Neuropathy and Alopecia
Paclitaxel is a chemotherapy drug that is used to treat breast cancer, one of the most common cancers. It causes two side effects very often - hair-loss and numbness.
- Trial name
- NCT03248193
- Testing
- Concomitant limb cryocompression and scalp cooling
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Chemotherapy Induced Alopecia
The Lily Device Trial
The goal of this clinical trial is to test if the Lily Device works to reduce chemotherapy induced hair loss in patients. It will also learn about the safety of the Lily Device.
- Trial name
- PREVAIL (NCT06786078)
- Testing
- Lily Device
- Where
- 5 sites in United States
- Volunteers
- 85 people
- Sponsor
- Luminate Medical, Inc.
Neoplasms, Alopecia
START: Swiss Taxotere Alopecia Prevention Trial
Primary objective: Rate of complete chemotherapy induced alopecia (WHO grade III or IV, physician grading) Secondary objective: Compliance to scalp cooling procedure Received number of cycles of chemotherapy in each subgroup…
- Trial name
- NCT01008774
- Testing
- Paxman Cooling Machine, Cold Caps
- Where
- Switzerland
- Volunteers
- 239 people
- Sponsor
- Sanofi
Neoplasm, Breast
Cooling Cap Trial to Prevent Permanent Chemotherapy-induced Alopecia in Breast Cancer Patients
This study aims to examine whether the PSCS2 is effective in reducing chemotherapy-induced alopecia in women with breast cancer undergoing neoadjuvant or adjuvant chemotherapy.
- Trial name
- NCT04678544
- Testing
- Scalp cooling system 2
- Where
- South Korea
- Volunteers
- 170 people
- Sponsor
- Samsung Medical Center
Alopecia, Chemotherapy-induced Alopecia
A Pilot Study to Evaluate the Use of the AMMA Portable Scalp Cooling System From Cooler Heads
Eligible patients will be recruited prior to initiation of chemotherapy for any stage breast or gynecologic cancer. Patients will undergo training in the use of the AMMA Portable Scalp Cooling System and will use the device…
- Conditions
- Alopecia, Chemotherapy-induced Alopecia, Hair Loss, Breast Cancer
- Trial name
- NCT05365243
- Testing
- AMMA Portalbe Scalp Cooling System
- Where
- United States
- Sponsor
- Cooler Heads Care Inc.
Breast Cancer, Chemotherapy-Induced Alopecia
Effects of a Web-Based Alopecia Education Program in Women With Breast Cancer
This randomized controlled trial evaluated the effects of a web-based alopecia education program on body image, self-esteem, chemotherapy-induced alopecia-related quality of life, and psychological well-being among women with…
- Trial name
- NCT07724314
- Testing
- Web-Based Alopecia Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Gulay Akman
Alopecia
A Study of PRP Treatment for Hair Loss After Cancer Therapy in Women With Breast Cancer
Participants who enroll in this study will undergo the platelet-rich plasma (PRP) study treatment. Participants will have a sample of blood collected and the platelets will be separated and then injected into half of the…
- Trial name
- NCT04459650
- Testing
- Platelet Rich Plasma system
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Alopecia
Efficacy, Safety and Tolerability of CG428 Cutaneous Solution on Chemotherapy Induced Alopecia; Controlled Study (ELAN)
Phase II clinical trial
- Trial name
- ELAN (NCT02919735)
- Testing
- CG 428 cutaneous solution
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Legacy Healthcare SA
Chemotherapy Induced Alopecia, Chemotherapy Side Effects
Pharmacokinetic Study of Topical Phenylephrine
Pharmacokinetic Study of Topical Phenylephrine
- Trial name
- NCT07033845
- Testing
- Phenylephrine
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Applied Biology, Inc.
Chemotherapy-induced Alopecia
Study To Evaluate The Efficacy And Safety Profile of ECOHAIR in Chemo-induced Alopecia.
This is a Phase 2, single-center study designed to determine the effect of ECOHAIR topical solution on scalp hair growth evaluated objectively ( images) and subjectively ( patient and investigator reports).
- Trial name
- NCT06020586
- Testing
- hair lotion
- Where
- Argentina
- Volunteers
- 22 people
- Sponsor
- Instituto de Oncología Ángel H. Roffo
Chemotherapy-induced Alopecia
Photobiomodulation Therapy in the Prevention and Management of Chemotherapy-Induced Alopecia
This study aims to investigate the effectiveness of photobiomodulation therapy (PBM) in the prevention and management of chemotherapy-induced alopecia (CIA).
- Trial name
- HairLight (NCT05177289)
- Testing
- Theradome® LH80 pro, Scalp cooling
- Where
- Belgium
- Volunteers
- 72 people
- Sponsor
- Jessa Hospital
Prevention of Chemotherapy-induced Myelosuppression
A Study of ALRN-6924 for Protection of Chemotherapy-Induced Side Effects in Patients With TP53-Mutant Breast Cancer
This is a Phase 1b open-label, single arm, multicenter, study of ALRN-6924 as a chemoprotection agent in patients with TP53-mutated HER2- breast cancer (stages IIa to IIIb) receiving neoadjuvant or adjuvant chemotherapy with…
- Trial name
- NCT05622058
- Testing
- ALRN-6924, TAC (doxorubicin 50 mg/m2; cyclophosphamide 500 mg/m2; docetaxel 75 mg/m2)
- Where
- 14 sites in United States, Bosnia and Herzegovina and 2 more
- Volunteers
- 6 people
- Sponsor
- Aileron Therapeutics, Inc.
Breast Cancer
Alopecia Prevention Scalp Cooling in Chinese Breast Cancer Patients
The Orbis Paxman Hair Loss Prevention System is a new equipment introduced to Hong Kong in 2017. Although this device has been widely used in the United States, Europe and Australia, acceptability, efficacy and safety data in…
- Trial name
- NCT04630080
- Testing
- Scalp cooling
- Where
- Hong Kong
- Volunteers
- 25 people
- Sponsor
- Chinese University of Hong Kong
Chemotherapy-induced Alopecia
"Impact of Chemotherapy-induced Alopecia on the Quality of Life of Women With Breast Cancer"
The main objective of this qualitative phenomenological study is to understand the impact of chemotherapy-induced alopecia, the quality of life of women with breast cancer from this experience.
- Trial name
- NCT02797223
- Testing
- Semi-structured interviews
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Alopecia
Evaluation of Scalp Cooling During Chemotherapy on Quality of Life and the Potential Role of Single Nucleotide Variations on Chemotherapy-Induced Alopecia and Hair Regrowth in the Appalachian Highlands Region
This single-blind, randomized controlled trial is proposed to assess the effects of the PAXMAN Scalp Cooling System on the quality of life of breast cancer subjects receiving any treatment regimen consisting of a chemotherapy…
- Trial name
- NCT07422376
- Testing
- Paxman Scalp Cooling System
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Charles Mays