Clinical trials: Chemotherapy-Related Cognitive Impairment
Gastroesophageal Cancer (GC), Postoperative Delirium (POD)
Cognitive Impact Associated With Surgery For Gastric Or Esophageal Cancer
The primary objective of this observational study is to investigate the incidence of Post Operative Delirium (POD) after gastroesophageal cancer surgery.
- Conditions
- Gastroesophageal Cancer (GC), Postoperative Delirium (POD), Quality of Life (QOL), Frailty
- Trial name
- CASE (NCT06687291)
- Where
- Sweden
- Volunteers
- 130 people
- Sponsor
- Karolinska Institutet
Effects of Chemotherapy, Cognitive Impairment
Cognitive Changes in Adult Cancer Survivors
This study will document the cognitive (mental) and functional abilities of newly diagnosed cancer patients. The study will also examine the changes in cognitive and functional abilities during and after chemotherapy (your cancer…
- Trial name
- CFCC (NCT01569932)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Washington University School of Medicine
Chemotherapy-Related Cognitive Impairment, Healthy
Telerehabilitation Cognitive Impairments Following Chemotherapy Usability Study
Develop a game-based upper-extremity motor and cognitive rehabilitation system using custom and adaptable virtual reality simulations.
- Trial name
- TCIFCU (NCT04839588)
- Testing
- Usability study
- Where
- 2 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Bright Cloud International Corp
Breast Neoplasms, Exercise Therapy
Aerobic Dance During Chemotherapy in Breast Cancer Patients With Cognitive Impairment
The goal of this clinical trial is to learn about breast cancer patients. The main questions it aims to answer are: Does Aerobic Dance During Chemotherapy Improve Cognitive Function in Breast Cancer Patients？ Does the efficacy of…
- Conditions
- Breast Neoplasms, Exercise Therapy, Chemotherapy-Related Cognitive Impairment, Cognitive Dysfunction
- Trial name
- ADANC (NCT06234150)
- Testing
- Aerobic dance, Fast-walking
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Cognitive Impairment, Chemobrain
Cognitive Impairment in Treated Breast Cancer Survivors: Possible Approaches
The investigators aim is to conduct a prospective study with three arms, involving non-metastatic breast cancer patients who underwent chemotherapy as part of their treatment and were on a form of hormone therapy at the time of…
- Trial name
- NCT06662474
- Testing
- 1. cognitive stimulation, 2. psychoeducation and cognitive stimulation, 3. no intervention
- Volunteers
- 120 people
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Cognitive Impairment, Hematologic Malignancies
Cognitive Impairment in Older Adults With Hematologic Malignancies
This cross-sectional study aims to determine the prevalence of cognitive impairment and evaluate its relationship with activities of daily living among older adults with hematologic malignancies receiving chemotherapy.
- Conditions
- Cognitive Impairment, Hematologic Malignancies, Chemotherapy Effect
- Trial name
- NCT07842679
- Volunteers
- 120 people
- Sponsor
- Assiut University
Chemo Brain, Chemotherapy-related Cognitive Impairment
Nicotinic Treatment of Post-Chemotherapy Subjective Cognitive Impairment: A Pilot Study
The purpose of this study is to evaluate the use of a nicotine patch as a treatment for problems with attention, learning and memory in breast cancer patients who are 1-5 years post chemotherapy.
- Conditions
- Chemo Brain, Chemotherapy-related Cognitive Impairment, Chemo Fog, Breast Cancer
- Trial name
- NCT02312934
- Testing
- Transdermal nicotine
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Vanderbilt University Medical Center
Chemo Fog
Ashwagandha for Cognitive Dysfunction
This is a 1:1 randomized double blinded placebo controlled trial. • To determine if ashwagandha can improve cognitive dysfunction when compared with placebo in patients undergoing chemotherapy for cancer.
- Trial name
- NCT04092647
- Testing
- Ashwagandha
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Sutter Health
Cancer, Chemotherapy
The Activity Intervention for Chemobrain
Cognitive dysfunction following chemotherapy is an adverse treatment effect that impacts the quality of life for many cancer survivors receiving this adjuvant therapy.
- Conditions
- Cancer, Chemotherapy, Cognitive Impairment
- Trial name
- TACTIC (NCT00495703)
- Testing
- Exercise, Usual Care
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Breast Cancer, Chemotherapy-related Cognitive Impairment
Evaluation of Cognitive Education Activities in Breast Cancer Patients Receiving Chemotherapy
Breast cancer is one of the most common cancer types worldwide and accounts for approximately 31% of all cancers in women. The global incidence of breast cancer is increasing, making it a significant public health problem.
- Trial name
- NCT07570251
- Testing
- Cognitive Function Training Activities
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Saglik Bilimleri Universitesi
Chinese Acupuncture
Chinese Acupuncture for Chemobrain in Elderly Cancer Patients
Elderly cancer patients would suffer cognitive impairment due to chemotherapy, and a series of neurocognitive symptoms, known as "chemobrain".
- Trial name
- NCT05876988
- Testing
- Chinese acupuncture
- Where
- China
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Chemotherapy-related Cognitive Impairment
Evaluating Cognitive Changes on Patients in Chemotherapy (ECCPC)
This randomized clinical trial aims to evaluate the impact of a structured low-intensity exercise program on cognitive function in adult cancer patients undergoing chemotherapy.
- Trial name
- (ECCPC) (NCT06950190)
- Testing
- Low-Intensity Walking Intervention, Control Group Intervention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ellis Medicine
Breast Cancer
Evaluation of Cognitive Management for Chemobrain in Patients Treated for Breast Cancer.
This project will investigate the efficacy of a cognitive remediation programme in patients treated for breast cancer. patients will be randomized between "no intervention" and "intervention programme".
- Trial name
- e-ONCOGITE (NCT05690828)
- Testing
- Cognitive remediation
- Where
- France
- Volunteers
- 164 people
- Sponsor
- Institut Bergonié
Breast Cancer
Amyloid Plaque Deposition in Chemotherapy-Induced Cognitive Impairment
The initial goal of the investigators interdisciplinary group of imagers, oncologists, neurologists, neuro-psychologists, and biostatisticians is to obtain proof of concept pilot data for eventual submission of a National Cancer…
- Trial name
- NCT02317783
- Testing
- [18F]Flutemetamol, [18F]fluoro-2-deoxy-D-glucose (FDG), Functional Magnetic Resonance Imaging (fMRI)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Utah
Cognitive Impairment
Cancer Related Cognitive Impairment After Chemotherapy: Evaluation of Potential Therapeutic Interventions
Background: Mindfulness has been applied to improve after cancer care by enhancing psychological well-being; however, little is known about its impact on cognitive impairment experienced by cancer patients after chemotherapy.
- Trial name
- NCT03736460
- Testing
- Mindfulness, Physical training
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- KU Leuven
Chemotherapy-Related Cognitive Impairment
Electroacupuncture for Chemotherapy-Related Cognitive Impairment
The objective of this trial is to evaluate the effect of electroacupuncture compared to sham acupuncture in preventing CRCI among breast cancer patients scheduled to undergo chemotherapy.
- Trial name
- NCT05941598
- Testing
- Electroacupuncture
- Volunteers
- 100 people
- Sponsor
- Beijing University of Chinese Medicine
Breast Cancer, Chemotherapy-Related Cognitive Impairment
Individualized Piano Instruction (IPI) for Improving Cognition in Breast Cancer Survivors.
The purpose of this study is to test the study method and procedure for individualized piano instruction (IPI) and its impact on chemotherapy related cognitive impairment (CRCI) symptoms.
- Trial name
- NCT05909813
- Testing
- Individualized Piano Keyboard Instruction
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Miami
Breast Cancer
Cognitive Training and Exercise for Women With Breast Cancer and Cognitive Impairment
Chemotherapy-related cognitive impairment is a prevalent and distressing condition among breast cancer survivors, adversely affecting memory, attention, and overall cognitive function, thereby diminishing quality of life.
- Trial name
- CHEMO-CogEx (NCT07017530)
- Testing
- Cognitive training, Psychoeducational therapy
- Where
- Spain
- Volunteers
- 220 people
- Sponsor
- Universidad de Extremadura
Breast Cancer
Chemotherapy Induced Cognitive Impairment
Chemotherapy is toxic and challenges everyone differently. Most chemotherapy side-effects are known and well documented. However, the phenomenon of "chemo fog" also known as "chemobrain" has not been fully investigated and is…
- Trial name
- CONCERT (NCT05740787)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Aberdeen
Cancer Survivors, Chemotherapy-related Cognitive Impairment
Neuroplasticity-Based Cognitive Remediation for Chemotherapy-Related Cognitive Impairment
The investigators propose to apply neuroplasticity-based computerized cognitive remediation (nCCR) to treat chemotherapy-related cognitive impairment (CRCI).
- Trial name
- NCT04230863
- Testing
- Neuroplasticity-based Computerized Cognitive Remediation
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Vanderbilt University Medical Center