Clinical trials: Chemotherapy-Related Symptoms
Cancer-related Problem/Condition, Cancer, Breast
A Self-Management Energy Conservation Program for Cancer-Related Fatigue
The purpose of this pilot study is to examine a 12-week self-management energy conservation program (ECAM)'s effects on fatigue, and secondarily on sleep, physical activity, anxiety and depression, self-efficacy, and beliefs…
- Conditions
- Cancer-related Problem/Condition, Cancer, Breast, Fatigue
- Trial name
- NCT03282214
- Testing
- Self-management energy conservation
- Where
- 2 sites in Thailand
- Volunteers
- 18 people
- Sponsor
- University of Michigan
Colorectal Cancer
Chemotherapy-Related Changes in Neurocognitive Function and Symptoms in Colorectal Cancer Patients: A Pilot Study
Cancer treatments have successfully improved cancer outcomes but frequently negatively impact quality of life in cancer survivors.
- Trial name
- NCT03683004
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Gastric Cancer
The Relationship Between Microsatellite Instability and Efficacy of Fluorouracil Based Adjuvant Chemotherapy in Gastric Cancer After Operation
The relationship between Microsatellite instability and efficacy of fluorouracil based adjuvant chemotherapy in gastric cancer after operation.
- Trial name
- NCT03485196
- Testing
- Microsatellite instability
- Where
- 3 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Affiliated Hospital of Qinghai University
Patients With Cancer
Ivabradine to Prevent Anthracycline-induced Cardiotoxicity
The aim of this study is to investigate protective effects of ivabradine in adult cancer patients undergoing anthracycline-based chemotherapy.
- Trial name
- NCT04030546
- Testing
- Ivabradine
- Where
- Lithuania
- Volunteers
- 128 people
- Sponsor
- Vilnius University
Cancer, Fatigue
Modafinil to Reduce Persistent Fatigue in Patients Following Treatment for Cancer
The purpose of this study is to determine the efficacy of modafinil with regard to reducing cancer-related fatigue in cancer patients following chemotherapy or radiation therapy.
- Conditions
- Cancer, Fatigue, Chemotherapy
- Trial name
- NCT00178373
- Testing
- Modafinil, sugar pill
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Rochester
Lymphedema Arm
Extracellular Fluid Changes During Neoadjuvant Chemotherapy
The purpose of this prospective clinical study is to evaluate whether neoadjuvant chemotherapy (NACT) is associated with an increase in extravascular (extracellular) fluid in the ipsilateral upper extremity, an early indicator of…
- Trial name
- NCT07315880
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people
- Sponsor
- Florence Nightingale Hospital, Istanbul
Myelodysplastic Syndrome, Effects of Chemotherapy
Electrophysiological Biomarkers of Chemotherapy-related Cognitive Impairment and Recovery
Broadly speaking, the goal of this study is to better understand the influence of chemotherapy treatment on the cognitive and neural mechanisms underlying human behavior.
- Conditions
- Myelodysplastic Syndrome, Effects of Chemotherapy, Mild Cognitive Impairment, Multiple Myeloma
- Trial name
- Chemobrain (NCT02767388)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Cardiotoxicity
Development of a Pharmacogenomic Panel for Early Detection of Chemotherapy- and Immunotherapy-Induced Cardiotoxicity.
To evaluate the use of a pharmacogenetic and pharmacoepigenetic panel for predicting chemotherapy- and immunotherapy-induced cardiotoxicity in cancer patients.
- Trial name
- NCT07663357
- Where
- 6 sites in Brazil
- Volunteers
- 1,000 people
- Sponsor
- Beneficência Portuguesa de São Paulo
Cardiac Toxicity, Sarcoma
Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00003937
- Testing
- cisplatin, dexrazoxane hydrochloride, doxorubicin hydrochloride
- Where
- 148 sites in United States, Australia and 4 more
- Volunteers
- 253 people
- Sponsor
- Children's Oncology Group
Acute Lymphoblastic Leukemia ALL
Children's Laughter and Fun Yoga as Adjunctive Pain Relief Following Chemotherapy.
The goal of this clinical trial is to learn if a home-based program that combines laughter and fun yoga can help lower pain in children receiving chemotherapy.
- Trial name
- CLAP (NCT07327138)
- Testing
- Laughter and Fun Yoga Program
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Bahaa Bou Dargham
Doxorubicin Induced Cardiomyopathy, Breast Cancer
Prevention Using Exercise Rehabilitation to Offset Cardiac Toxicities Induced Via Chemotherapy
The purpose of this study is to identify patients at risk for future heart failure using novel markers of early cardiac damage and determine if exercise training can improve these emerging markers as well as overall fitness and…
- Conditions
- Doxorubicin Induced Cardiomyopathy, Breast Cancer, Gastric Cancer, Leukemia
- Trial name
- HF-PROACTIVE (NCT02796365)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Henry Ford Health System
Nausea Post Chemotherapy, Vomiting
Pharmacokinetic and Pharmacodynamic Evaluation of Formulations of Δ9-THC
Study based on the pharmacokinetic, pharmacodynamic, safety and stability evaluation of 3 standardized formulations of THC, to be used in healthy volunteers and post-chemotherapy patients as an adjuvant in the symptomatic…
- Conditions
- Nausea Post Chemotherapy, Vomiting, Cancer Pain, Cancer Related Pain
- Trial name
- NCT05272865
- Testing
- Pharmacokinetic and pharmacodynamic profile of THC oral formulations with Dronabinol as comparator
- Where
- Colombia
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- LaSanta S A S
Symptom Distress During Breast Cancer Treatment
Trajectory Analysis of Symptom Distress and Cancer-related Fatigue After Adjuvant Chemotherapy in Breast Cancer Female
When receiving adjuvant chemotherapy, a variety of symptoms will appear and it is very painful. These symptoms occur at the same time and are related to each other.
- Trial name
- NCT04911699
- Testing
- breast adenocarcinoma receiving chemotherapy, Control-for
- Volunteers
- 120 people
- Sponsor
- Taipei Medical University
Leukemia, Lymphoma
Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Advanced Hematologic Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Peripheral stem cell transplantation may be able to replace immune cells that were destroyed by chemotherapy…
- Conditions
- Leukemia, Lymphoma, Myelodysplastic Syndromes
- Trial name
- NCT00004114
- Testing
- filgrastim, cyclophosphamide, cytarabine
- Sponsor
- Jonsson Comprehensive Cancer Center
Fatigue, Breast Cancer
Wide Spectrum Micronutrients Supplementation in Patients With Cancer Related Fatigue During Neoadjuvant and Adjuvant Chemotherapy
The goal of this clinical trial is to test the effect of the administration of APPORTAL® in addition to the SoC (recommended physical exercise), in patients with breast cancer, suffering from fatigue during neoadjuvant and…
- Trial name
- NCT06137833
- Testing
- APPOPRTAL®
- Where
- 5 sites in Italy
- Volunteers
- 92 people
- Sponsor
- Pharmanutra S.p.a.
Depression
Antidepressant Treatment of AIDS Related Depression.
To test the effectiveness treating AIDS related depression with imipramine hydrochloride. Depression syndromes are commonly associated with chronic, disabling, and fatal diseases.
- Trial name
- NCT00000390
- Testing
- Imipramine hydrochloride
- Where
- United States
- Sponsor
- GEIGY Pharmaceuticals
Opioid Use Disorder, HIV
Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans
Opioid use disorder (OUD) confers a higher risk of acquiring and transmitting infectious diseases, which may have long-term health consequences in Veterans.
- Conditions
- Opioid Use Disorder, HIV, Hepatitis C Virus, Gonorrhea
- Trial name
- NCT06766331
- Testing
- Integrated care
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cervical Cancer, Chronic Myeloproliferative Disorders
Dalteparin to Prevent Complications in Cancer Patients Receiving Chemotherapy Through a Catheter
RATIONALE: The use of dalteparin may be able to prevent complications caused by the use of a catheter to supply chemotherapy to cancer patients. It is not yet known if dalteparin is effective in reducing these complications.
- Conditions
- Cervical Cancer, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
- Trial name
- NCT00006083
- Testing
- Fragmin
- Where
- United States
- Sponsor
- Jonsson Comprehensive Cancer Center
Cardiotoxicity
Empagliflozin in the Prevention of Cardiotoxicity in Cancer Patients Undergoing Chemotherapy Based on Anthracyclines
EMPACT (EMPAgliflozin in prevention of chemotherapy-related CardioToxicity) study is a randomized, multi-center, placebo-controlled, double-blind trial to evaluate efficacy of empagliflozin in prevention of left ventricular (LV)…
- Trial name
- EMPACT (NCT05271162)
- Testing
- Empagliflozin 10 MG
- Where
- 2 sites in Poland
- Volunteers
- 220 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Dysgeusia, Acupressure
Application of Auricular Point Sticking in Patients With Taste Alteration
To explore the intervention effect of auricular point sticking on chemotherapy-induced taste alterations in cancer patients, and analyze its relationship with quality of life, nutritional status and psychology of patients.
- Conditions
- Dysgeusia, Acupressure, Chemotherapy Effect
- Trial name
- NCT05868850
- Testing
- auricular point sticking
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Jiangnan University