Clinical trials: Chemotherapy-induced Alopecia
Breast Neoplasms, Alopecia
Effect of Cryotherapy in the Prevention of Madarosis Produced by Chemotherapy in Breast Cancer Patients
Chemotherapy-induced alopecia (CIA) significantly compromises body image in breast cancer patients, particularly when involving eyebrow and eyelash loss (madarosis).
- Conditions
- Breast Neoplasms, Alopecia, Madarosis, Eyebrow Diseases
- Trial name
- NCT06955702
- Testing
- cryotherapy for chemotherapy-induced madarosis
- Where
- 2 sites in Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Gynecologic Cancer, Chemotherapy-Induced Change
Scalp Cooling in Gynecologic Cancer Patients
In gynecologic cancers, many common chemotherapy agents can lead to chemotherapy-induced alopecia. Currently scalp cooling is the most well studied preventive measure.
- Trial name
- NCT04168242
- Testing
- Scalp cooling Paxman Orbis II system, Standard treatment
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- The University of Hong Kong
Alopecia, Chemotherapy-Induced Change
Keratinocyte Growth Factor- Hair Serum for the Prevention of Chemotherapy Induced Alopecia
Primary aim is to provide a preliminary assessment of the efficacy of the investigational topical formula, KGF-HS, as a prophylactic treatment for chemotherapy induced alopecia.
- Conditions
- Alopecia, Chemotherapy-Induced Change, Hair Loss, Alopecia Drugs
- Trial name
- NCT04554732
- Testing
- Keratinocyte growth factor
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Arizona
Breast Cancer, Early-stage Breast Cancer
Portable Scalp Cooling System (PSCS) to Prevent Hair Loss for Breast Cancer Patients (Cooler Heads)
The purpose of this post-market, prospective study is to assess the ability of AMMA to prevent hair loss in women receiving chemotherapy (CT) for early-stage breast cancer.
- Conditions
- Breast Cancer, Early-stage Breast Cancer, Hair Loss, Alopecia
- Trial name
- NCT06215469
- Testing
- Amma Portable Scalp Cooling System (PSCS), Questionnaires
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Alopecia
Scalp Cooling for Chemotherapy-Induced Alopecia in Patients of Color
The purpose of this study is to evaluate hairstyling techniques aimed at increasing efficacy of scalp cooling in the prevention of chemotherapy-induced alopecia, determine scalp cooling effect on persistent chemotherapy-induced…
- Trial name
- NCT05213936
- Testing
- Scalp cooling with hairstyle, Scalp cooling with conditioner and water emulsion
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Montefiore Medical Center
Breast Cancer, Alopecia
Scalp Cooling to Prevent Chemo-induced Hair Loss
Determine that the Orbis Paxman Hair Loss Prevention System is safe and effective in reducing chemotherapy-induced alopecia in woman with breast cancer undergoing neoadjuvant or adjuvant chemotherapy.
- Trial name
- SCALP (NCT01986140)
- Testing
- PAXMAN Orbis Scalp Cooler, Control No treatment
- Where
- 7 sites in United States
- Volunteers
- 236 people
- Sponsor
- Julie Nangia
Chemotherapy Induced Alopecia, Chemotherapy Side Effects
Pharmacokinetic Study of DA-020
Pharmacokinetic Study of DA-020
- Trial name
- NCT07402330
- Testing
- DA-020 (0.1%), DA-020 (0.2%), DA-020 (0.5%)
- Where
- 2 sites in Brazil, Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Applied Biology, Inc.
Permanent Chemotherapy-induced Alopecia
Effect of Low-Dose Oral Minoxidil as Treatment of Permanent Chemotherapy-Induced Alopecia
An open label, pilot study involving the use of low dose oral minoxidil to treat permanent chemotherapy-induced alopecia.
- Trial name
- NCT03831334
- Testing
- oral minoxidil
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Northwestern University
Chemotherapy-induced Alopecia
Prevention of Alopecia in Patients With Localised Breast Cancer
The prevention of chemotherapy-induced alopecia (CIA) is still imperfectly managed in France. Strengthening the evidence base on the benefits of strategies to prevent CIA, based on robust methodologies, remains a prerequisite for…
- Trial name
- ICELAND (NCT06011525)
- Testing
- standard cold cap, scalp-cooling technique
- Where
- 3 sites in France
- Volunteers
- 196 people
- Sponsor
- Centre Francois Baclesse
Breast Cancer, Chemotherapy-induced Alopecia
PBMT for the Management of CIA ( HAIRLASER )
Chemotherapy (CT) remains an important treatment modality for breast cancer patients. Unfortunately, this systemic treatment comes with many quality of life impairing complications.
- Conditions
- Breast Cancer, Chemotherapy-induced Alopecia, Alopecia
- Trial name
- NCT04036994
- Testing
- Photobiomodulation therapy
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Hasselt University
Alopecia, Chemotherapy-induced Alopecia
Study to Assess the Ability of the Portable Scalp Cooling System (PSCS) to Prevent Hair Loss
The purpose of this prospective study is to assess the ability of AMMA to prevent hair loss in women receiving chemotherapy (CT) for early-stage breast cancer.
- Conditions
- Alopecia, Chemotherapy-induced Alopecia, Hair Loss, Breast Cancer
- Trial name
- NCT05484973
- Testing
- AMMA Portalbe Scalp Cooling System
- Where
- 2 sites in United States
- Volunteers
- 99 people
- Sponsor
- Cooler Heads Care Inc.
Non-Metastatic Breast Cancer
Study of Chemotherapy-Induced Hair Changes and Alopecia, Skin Aging and Nail Changes in Women With Non-Metastatic Breast Cancer
The purpose of this study is to see how many patients develop hair, skin and nail changes due to cancer treatments. The investigators would like to study the clinical factors, genetic markers, and impact on patients'…
- Trial name
- NCT02530177
- Testing
- Clinical Assessments, Questionnaires, Saliva sample
- Where
- United States
- Volunteers
- 546 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Alopecia
Evaluation of Scalp Cooling During Chemotherapy on Quality of Life and the Potential Role of Single Nucleotide Variations on Chemotherapy-Induced Alopecia and Hair Regrowth in the Appalachian Highlands Region
This single-blind, randomized controlled trial is proposed to assess the effects of the PAXMAN Scalp Cooling System on the quality of life of breast cancer subjects receiving any treatment regimen consisting of a chemotherapy…
- Trial name
- NCT07422376
- Testing
- Paxman Scalp Cooling System
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Charles Mays
Breast Cancer
Alopecia Prevention Scalp Cooling in Chinese Breast Cancer Patients
The Orbis Paxman Hair Loss Prevention System is a new equipment introduced to Hong Kong in 2017. Although this device has been widely used in the United States, Europe and Australia, acceptability, efficacy and safety data in…
- Trial name
- NCT04630080
- Testing
- Scalp cooling
- Where
- Hong Kong
- Volunteers
- 25 people
- Sponsor
- Chinese University of Hong Kong
Breast Cancer, Breast - Female
CARE (Chemotherapy Alopecia REduction)
The goal of this research study is to determine if the DigniCap Scalp Cooling System can help prevent chemotherapy-induced hair loss in Black patients.
- Conditions
- Breast Cancer, Breast - Female, Breast Cancer Stage I, Breast Cancer Stage II
- Trial name
- CARE (NCT07201389)
- Testing
- Scalp Cooling by DigniCap
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- George Washington University
Chemotherapy Induced Alopecia, Chemotherapy Side Effects
Pharmacokinetic Study of Topical Phenylephrine
Pharmacokinetic Study of Topical Phenylephrine
- Trial name
- NCT07033845
- Testing
- Phenylephrine
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Applied Biology, Inc.
Breast Cancer, Ovarian Cancer
Efficacy of Paxman Scalp Cooling to Prevent Chemo Induced Alopecia in Black Patients With Breast or GYN Cancers
This study will measure the efficacy of scalp cooling with the Paxman Scalp Cooling (PSC) device in a diverse patient population with success measured as prevention of more than 50% hair loss during chemotherapy.
- Conditions
- Breast Cancer, Ovarian Cancer, Gynecologic Neoplasm, Endometrial Cancer
- Trial name
- NCT04626895
- Testing
- Paxman Scalp Cooling Device
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Medstar Health Research Institute
Chemotherapy-induced Alopecia
Study To Evaluate The Efficacy And Safety Profile of ECOHAIR in Chemo-induced Alopecia.
This is a Phase 2, single-center study designed to determine the effect of ECOHAIR topical solution on scalp hair growth evaluated objectively ( images) and subjectively ( patient and investigator reports).
- Trial name
- NCT06020586
- Testing
- hair lotion
- Where
- Argentina
- Volunteers
- 22 people
- Sponsor
- Instituto de Oncología Ángel H. Roffo
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
Minoxidil With or Without Low-Level Red-Light Therapy for Improving Chemotherapy-Induced Alopecia in Breast Cancer Patients
This phase II trial compares the safety and effectiveness of topical minoxidil alone to topical minoxidil in combination with low-level red-light therapy for improving chemotherapy-induced hair loss or thinning (alopecia).
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8
- Trial name
- NCT07594678
- Testing
- Electronic Health Record Review, Minoxidil, Revian RED LED-light cap
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Chemotherapy-induced Alopecia
"Impact of Chemotherapy-induced Alopecia on the Quality of Life of Women With Breast Cancer"
The main objective of this qualitative phenomenological study is to understand the impact of chemotherapy-induced alopecia, the quality of life of women with breast cancer from this experience.
- Trial name
- NCT02797223
- Testing
- Semi-structured interviews
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau