Clinical trials: Chemotherapy-induced Neuropathy
Peripheral Neuropathy
Optimizing Integrative Oncology Approaches to Address Chemotherapy-induced Peripheral Neuropathy in Gastrointestinal (GI) Cancer Patients: A SMART Pilot Study
The objective of the proposed pilot is to test the feasibility, acceptability, and preliminary efficacy of a 16-week sequential, multiple assessment randomized trial (SMART), which includes virtual Tai Chi/Qi Gong or α- Lipoic…
- Trial name
- NCT07501663
- Testing
- Tai Chi/Qi Gong, α- Lipoic acid, Acupuncture
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy (CIPN)
Efficacy of Spinal Cord Stimulation in Chemotherapy-Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a frequent and debilitating side effect of many cancer treatments. It affects 28 to 48% of patients receiving chemotherapy.
- Conditions
- Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy (CIPN), Cancer-related Pain
- Trial name
- CHEMOSTIM (NCT07579611)
- Testing
- Spinal cord stimulation (FAST mode)
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Peripheral Nervous System Disorders, Breast Neoplasms
Heading Off Peripheral Neuropathy With Exercise
Chemotherapy for the treatment of breast cancer can affect nerves and muscles leading to loss of sensation in the hands and feet for feeling hot and cold, difficulty walking, and muscle weakness.
- Conditions
- Peripheral Nervous System Disorders, Breast Neoplasms, Chemotherapy
- Trial name
- HOPE (NCT00869804)
- Testing
- Aerobic/ Resistance Exercise Intervention, Attention control
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Nebraska
Chemotherapy-induced Peripheral Neuropathy (CIPN), Neuropathic Pain
Use of PEA and Scutellaria in Synergy With Therapeutic Exercise in Chemotherapy-induced Peripheral Neuropathy (CIPN): a Clinical Trial
This study aims to find out if taking specific dietary supplements (PEA and Scutellaria) along with therapeutic exercise can help reduce nerve pain and damage caused by chemotherapy.
- Trial name
- NCT07352514
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Palermo
Breast Cancer, Chemotherapy-induced Peripheral Neuropathy
Involvement of SK3 Calcium Channel in Taxane Neuropathy
Taxane neuropathy is a common and long-term side effect of long-term morbidity in patients surviving cancer. No preventive or symptomatic treatment has been shown to be effective.
- Conditions
- Breast Cancer, Chemotherapy-induced Peripheral Neuropathy, Prostate Cancer
- Trial name
- NEUROTAX (NCT03816904)
- Testing
- Blood samples
- Where
- 2 sites in France
- Volunteers
- 97 people
- Sponsor
- University Hospital, Tours
Chemotherapeutic Agent Toxicity, Neurotoxicity
Electrical Stimulation Therapy Using the MC5-A Scrambler in Reducing Peripheral Neuropathy Caused by Chemotherapy
RATIONALE: Electronic stimulation using a MC5-A Scrambler may help relieve pain in patients who develop peripheral neuropathy while undergoing chemotherapy treatments for cancer.
- Conditions
- Chemotherapeutic Agent Toxicity, Neurotoxicity, Pain, Peripheral Neuropathy
- Trial name
- NCT00952848
- Testing
- questionnaire administration, Sensory Neuropathy Scale instrument, Quality of Life instrument
- Volunteers
- 18 people
- Sponsor
- Virginia Commonwealth University
Chemotherapy-induced Peripheral Neuropathy, Breast Cancer Female
Acupuncture Treatment of Chemotherapy-Induced Peripheral Neuropathy in Women
This pilot study aims to evaluate the feasibility to conduct a study of acupuncture treatment (AT) for Chemotherapy-Induced Peripheral Neuropathy (CIPN) at Huntsman Cancer Institute and to investigate changes in physiological…
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Breast Cancer Female, Gynecologic Cancer
- Trial name
- NCT04067544
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Utah
Peripheral Sensory Neuropathy
Clinical Study on Acetyl-L-Carnitine
Chemotherapy-induced peripheral neuropathy (CIPN) is a common clinical dose-limiting adverse drug reaction, and the primary manifestations are different degree of neuromotor, sensorineural and autonomic nervous dysfunction.
- Trial name
- NCT01526564
- Testing
- Acetylcarnitine
- Volunteers
- 239 people
- Sponsor
- Lee's Pharmaceutical Limited
Chemotherapy Induced Peripheral Neuropathy
Randomized Clinical Investigation of Photobiomodulation (PBM) for the Management of Early Peripheral Neuropathy Related to Medical Oncologic Therapy
Chemotherapy-induced peripheral neuropathy (CIPN) is one of the common complications of cancer treatment and involves paresthesia, numbness and/or burning pain in distal limbs.
- Trial name
- ENL (NCT07681921)
- Testing
- Photobiomodulation
- Where
- Belgium
- Volunteers
- 98 people
- Sponsor
- Jules Bordet Institute
Chemotherapy-induced Peripheral Neuropathy, CIPN - Chemotherapy-Induced Peripheral Neuropathy
High-concentration Capsaicin Patch for the Prevention of Paclitaxel-induced Peripheral Neuropathy
This research study is for participants who are receiving paclitaxel infusion as part of their cancer treatment. The purpose of this study is to test the effectiveness of the Food and Drug Administration (FDA) approved…
- Trial name
- NCT07834281
- Testing
- High Concentration Capsaicin Patch (HCCP)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Case Comprehensive Cancer Center
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Assessing Functional Impairments in Patients With Chemotherapy-Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a severe side effect of several anti-cancer agents. Typical symptoms include tingling and hypoesthesia in the fingertips and/or toes, which substantially impair patients'…
- Trial name
- Assess CIPN (NCT07315334)
- Testing
- Questionnaire and Physical Exam
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Paracelsus Medical University
Chemotherapy-Induced Peripheral Neuropathy, Refractory Chemotherapy-Induced Peripheral Neuropathy
A Single-Arm, Prospective Study of Papaverine for the Treatment of Refractory Peripheral Neuropathy Induced by Taxane-Based Chemotherapy
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and often long-lasting side effect of cancer treatment. Patients may experience numbness, tingling, pain, burning sensations, weakness, or difficulty with walking and…
- Conditions
- Chemotherapy-Induced Peripheral Neuropathy, Refractory Chemotherapy-Induced Peripheral Neuropathy, Paclitaxel-Induced Peripheral Neuropathy
- Trial name
- NCT07572461
- Testing
- Papaverine hydrochloride injection
- Volunteers
- 43 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine