Clinical trials: Chemotherapy-induced Peripheral Neuropathy (CIPN), open to volunteers
Chemotherapy
A Stuty on the Treatment and Nursing Care of CIPN Patients With Traditional Chinese Medicine Hot Package
The combination of platinum and taxane drugs has a chemotherapy-induced peripheral neuropathy (CIPN) rate of 73% to 83%. Its symptoms can not only limit daily activities and cause a variety of accidental injuries, but also easily…
- Trial name
- NCT06492083
- Testing
- traditional Chinese medicine hot bag
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Neuropathy, Cancer
Daily Hand-Held Vibration Therapy
The purpose of this pilot study is to determine the safety and feasibility of a daily 3-minute hand-held vibration therapy intervention to reduce the severity of CIPN in the hands.
- Conditions
- Neuropathy, Cancer, Chemotherapeutic Drug - Induced Nephropathy, Chemotherapeutic Toxicity
- Trial name
- NCT04207437
- Testing
- Vibration therapy
- Where
- 3 sites in United States
- Volunteers
- 16 people
- Sponsor
- Indiana University
CIPN - Chemotherapy-Induced Peripheral Neuropathy, Breast Cancer
Network-Guided Theta Burst Stimulation for Breast Cancer With Chemotherapy-Induced Peripheral Neuropathy: Clinical and fMRI Biomarker Evidence
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating complication among breast cancer survivors, frequently associated with chronic neuropathic pain that remains inadequately controlled by…
- Trial name
- CIPN TBS (NCT07695415)
- Testing
- pcTBS
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Polyneuropathy, Breast Cancer
A New Cancer Rehabilitation Process for Chemotherapy-Induced Foot Neuropathy Using Orthopedic Devices
The goal of this clinical study is to evaluate a new process for assessing and alleviating chemotherapy-induced peripheral neuropathy in the feet in patients treated with chemotherapy for early stage breast cancer.
- Trial name
- FOTNEV (NCT06904989)
- Testing
- Silicone orthosis, Standard Treatment
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Vastra Gotaland Region
CIPN
Chemotherapy Induced Peripheral Neurotoxicity (CIPN): Why Should we Care
This is a pilot, observational, cross-sectional, study on socio-economic burden related to chemotherapy-induced peripheral neurotoxicity (CIPN).
- Trial name
- CIPN COST (NCT04986891)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- University of Milano Bicocca
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Stibium Metallicum Praeparatum D6 Versus Placebo in the Reduction of Paclitaxel-induced Peripheral Neurotoxicity
Chemotherapy induced peripheral neuropathy (CIPN) is one of the most limiting side effects of chemotherapy and often leads to adaptations in the protocol of the chemotherapy including dose reduction or even discontinuation of…
- Trial name
- STING-CIPN (NCT04715542)
- Testing
- Stibium metallicum praeparatum 6x
- Volunteers
- 86 people
- Sponsor
- University of Bern
CIPN - Chemotherapy-Induced Peripheral Neuropathy, Breast Cancer
Effects of Cryotherapy on Taxane-Induced Neuropathy in Patients With Breast Cancer
Due to well-proven survival benefit, paclitaxel and other taxane-based chemotherapies are first-line agents for both the adjuvant and neoadjuvant treatment of early stage breast cancer.
- Trial name
- NCT05928429
- Testing
- Elasto-Gel™ mitts for hands: TM7008, and slippers for feet: SL3000; Southwest Technologies, Inc., North Kansas City, MO, USA
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Maria Lendorf
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Intrathecal Ziconotide in Chemotherapy Induced Peripheral Neuropathy
The purpose of this observational, data collection, research is to evaluate if ziconotide, a commercially approved medication given by a FDA cleared intrathecal pump, for chronic pain is effective in the treatment of…
- Trial name
- NCT07499882
- Testing
- Ziconotide
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Christian Hospital Northeast Northwest
Breast Cancer, CIPN - Chemotherapy-Induced Peripheral Neuropathy
Efficacy and Safety of Hyperbaric Oxygen Therapy in Improving Nab-paclitaxel-Induced Peripheral Neuropathy
The goal of this research is to assess whether hyperbaric oxygen therapy can alleviate the symptoms of Nab-paclitaxel-induced peripheral neuropathy and improve patient-reported quality of life.
- Conditions
- Breast Cancer, CIPN - Chemotherapy-Induced Peripheral Neuropathy, Paclitaxel-induced Peripheral Neuropathy
- Trial name
- NCT07410169
- Testing
- Hyperbaric oxygen treatment, Standard Care (in control arm)
- Where
- 2 sites in China
- Volunteers
- 160 people
- Sponsor
- Guangdong Provincial People's Hospital
Chemotherapy Induced Peripheral Neuropathy (CIPN)
The Lilac Device Trial - IMPACT: A Clinical Investigation on IMproving Peripheral Neuropathy Induced by Chemotherapy With Advanced Compression Technology - A Safety and Efficacy Study
Chemotherapy drugs, used in the treatment of cancer, have the potential of inducing peripheral neuropathy (PN) as a side effect. This side effect is commonly referred to as CIPN, or chemotherapy-induced peripheral neuropathy.
- Trial name
- IMPACT (NCT07142304)
- Testing
- The Lilac Device
- Where
- 18 sites in United States, Ireland
- Volunteers
- 142 people
- Sponsor
- Luminate Medical, Inc.
Gynaecological, Urological or Rectal Cancer, Chemotherapy-Induced Peripheral Neuropathy
The Use of Acupuncture to Reduce Chemotherapy Induced Peripheral Neuropathy in Gynaecological Cancer Patients
Objectives: To explore the feasibility and effectiveness of acupuncture on reducing Chemotherapy Induced Peripheral Neuropathy (CIPN) in gynaecological cancer patients who have received carboplatin and paclitaxel chemotherapy…
- Conditions
- Gynaecological, Urological or Rectal Cancer, Chemotherapy-Induced Peripheral Neuropathy, Acupuncture
- Trial name
- AcuCIN (NCT06769061)
- Testing
- Acupuncture
- Where
- Hong Kong
- Volunteers
- 75 people
- Sponsor
- Karen Kar Loen CHAN
Cancer
Effect of Dance-based Multimodal Exercise for Managing CIPN in Cancer Patients
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a significant and distressing symptom experienced by cancer patients with different cancer types.
- Trial name
- NCT07632482
- Testing
- dance-based multimodal exercise, Exercise education
- Volunteers
- 76 people
- Sponsor
- Chinese University of Hong Kong
Breast Cancer, Chemotherapy-induced Peripheral Neuropathy (CIPN)
Acupuncture and Compression for the Prevention of CIPN in Breast Cancer Patients
As a core component of comprehensive breast cancer treatment, chemotherapy frequently induces chemotherapy-induced peripheral neuropathy (CIPN), particularly with taxane-based agents.
- Trial name
- NCT07377279
- Testing
- Compression, Acupuncture, Compression combined with acupuncture
- Where
- China
- Volunteers
- 384 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Chemotherapy-induced Peripheral Neuropathy
Study of SIR2501 in Solid Tumor Patients Receiving Paclitaxel
This Phase 2, open-label study will evaluate the safety, tolerability, and pharmacokinetics of SIR2501 in adults with solid tumors who are scheduled to receive paclitaxel-based chemotherapy.
- Trial name
- NCT07765446
- Testing
- SIR2501
- Where
- 5 sites in United States
- Volunteers
- 18 people
- Sponsor
- Sironax USA, Inc.
Chemotherapy Induced Peripheral Neuropathy (CIPN)
Assessing Functional Impairments in Patients With Chemotherapy-Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a severe side effect of several anti-cancer agents. Typical symptoms include tingling and hypoesthesia in the fingertips and/or toes, which substantially impair patients'…
- Trial name
- Assess CIPN (NCT07315334)
- Testing
- Questionnaire and Physical Exam
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Paracelsus Medical University
Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy (CIPN)
Efficacy of Spinal Cord Stimulation in Chemotherapy-Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a frequent and debilitating side effect of many cancer treatments. It affects 28 to 48% of patients receiving chemotherapy.
- Conditions
- Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy (CIPN), Cancer-related Pain
- Trial name
- CHEMOSTIM (NCT07579611)
- Testing
- Spinal cord stimulation (FAST mode)
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
CIPN - Chemotherapy-Induced Peripheral Neuropathy
Safety and Efficacy of JMKX000189 for Chemotherapy-Induced Peripheral Neuropathy
This Phase Ib clinical trial aims to evaluate the safety, tolerability, and preliminary efficacy of JMKX000189 tablets in participants with chemotherapy-induced peripheral neuropathy (CIPN).
- Trial name
- NCT07601386
- Testing
- JMKX000189
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Shanghai Jeyou Pharmaceutical Co., Ltd.
Chemotherapy Induced Neuropathic Pain, Neuropathy Toxic
Prospective Exploratory Study of a Multiomic Blood Biomarker Panel to Predict Chemotherapy-Induced Peripheral Neuropathy (CIPN)
The goal of this prospective, multicenter, observational cohort study with longitudinal blood sampling and standardized neurological evaluation over 6 months is to identify biomarkers to predict the overall occurrence of chronic…
- Conditions
- Chemotherapy Induced Neuropathic Pain, Neuropathy Toxic, Taxane-induced Peripheral Neuropathy, Oxaliplatin Induced Peripheral Neuropathy in Cancer Patients
- Trial name
- PRECISE1 (NCT07511569)
- Testing
- longitudinal blood sampling and standardized neurological evaluation over 6 months
- Volunteers
- 192 people
- Sponsor
- Centre Hospitalier de Bligny
Chemotherapy-induced Peripheral Neuropathy
Neural and Immune Correlates of CIPN and Possible Analgesic Effect of Non-invasive Motor Cortex Stimulation
Over half of cancer patients receiving common chemotherapy treatments experience painful nerve damage called chemotherapy-induced peripheral neuropathy (CIPN).
- Trial name
- NIBS4CIPN (NCT06522685)
- Testing
- transcranial direct current stimulation Soterix REMOTE 1x1 miniCT
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Morgan State University
Chemotherapy-induced Peripheral Neuropathy (CIPN)
AYUrvedic Foot Massage for Symtoms of Taxane-induced Peripheral nEuroPathy
Chemotherapy-induced peripheral neuropathy (CIPN) affects approximately 40% of patients treated with taxanes. These agents may cause burning pain, paresthesia, numbness, and loss of proprioceptive sensitivity, which can reduce…
- Trial name
- AYU-STEP (NCT07884071)
- Testing
- Manual manipulation of the feet.
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- European Institute of Oncology