Clinical trials: Chest CT Scan
Breast Cancer
Opportunistic Breast Cancer Screening Using Non-Contrast Chest CT
The goal of this observational study is to evaluate the feasibility and effectiveness of using non-contrast chest computed tomography scans for opportunistic breast cancer screening, and to further compare its diagnostic…
- Trial name
- OPBCS-CT (NCT07557654)
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Fudan University
Non-small Cell Lung Cancer
Therapeutic Resistance Prediction of Tyrosine Kinase Inhibitors
The investigators propose a non-invasive prognostic tool for TKIs resistance in patients with stage IV EGFR-mutant non-small cell lung cancer (NSCLC) by computed tomography phenotypic features, which can be conveniently…
- Trial name
- NCT02851329
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Sciences
Cardiac Defects, Disorder; Heart, Functional, Postoperative, Cardiac Surgery
Chest CT With Iterative Reconstruction as an Alternative to Conventional Chest X-ray Prior to Heart Surgery
To assess if information about aortic calcification obtained from routine preoperative ultra low-dose chest CT lowers the postoperative stroke rate in patients undergoing heart surgery by optimizing surgical strategy compared to…
- Conditions
- Cardiac Defects, Disorder; Heart, Functional, Postoperative, Cardiac Surgery, Stroke
- Trial name
- CRICKET (NCT02173470)
- Testing
- CT scan
- Where
- 3 sites in Hungary, Netherlands
- Volunteers
- 866 people
- Sponsor
- UMC Utrecht
Community-acquired Pneumonia, Dyspnea
Chest CT-scan for the Diagnosis of Community-acquired Pneumonia
Primary objective : to estimate impact of CT-scan on diagnostic for emergency department (ED) patients with suspected Community-acquired Pneumonia (CAP).
- Trial name
- PACSCAN (NCT01574066)
- Testing
- Chest CT-scan
- Where
- 4 sites in France
- Volunteers
- 339 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Non-small Cell Lung Cancer
Utility of Routine Cervical Mediastinoscopy in Clinical Stage I Non-Small Cell Lung Cancer (NSCLC)
To prospectively look at the utility of routine cervical mediastinoscopy (lymph node biopsy) in patients with clinically staged T2N0M0 NSCLC, as well as patients with clinically staged T1N0M0 NSCLC with a high maxSUV of the…
- Trial name
- NCT01146366
- Where
- 4 sites in United States
- Volunteers
- 111 people
- Sponsor
- Jennifer Bell
Lung Cancer
Body Composition Analysis for Patient With Lung Cancer Using Computed Tomography Image Analysis
Rationale: With 1.6 million new cases diagnosed each year and 1.3 million deaths, lung cancer is the leading cancer-related death worldwide and it represents a pressing health issue.
- Trial name
- BAT-SCAN (NCT01887769)
- Where
- Canada
- Volunteers
- 1,000 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Pulmonary Embolism (Diagnosis), Pulmonary Embolism Acute
Role of n On-contrast Chest CT (NCCT) Based CT V: Q in Patients With Acute Pulmonary Embolism (aPE)
We are doing the research to see if a CT scan without the dye can help find pulmonary emboli. If you agree to join the study, you will be asked to sign this consent form before we do any research procedures.
- Trial name
- NCT07527117
- Testing
- Additional CT acquisition at low dose (1- 2 mSv)
- Where
- 2 sites in United States
- Volunteers
- 750 people
- Sponsor
- Massachusetts General Hospital
Subjects at High Risk of Lung Cancer Due to Smoking
Continuous Observation of Smoking Subject
The purpose of this study is to offer annual low-dose spiral CT radiological examination for 5 years to 5000 volunteers from the general population who are considered to be at high risk of developing lung cancer.
- Trial name
- COSMOS (NCT01248806)
- Testing
- Low dose CT scan
- Where
- Italy
- Volunteers
- 5,203 people
- Sponsor
- European Institute of Oncology
Pneumonia, Diagnoses Disease
Ultra-low Dose Chest Computed Tomography: a Rule-out Tool for Community-acquired Pneumonia
This is a randomized study that sought to compare the rule-out capacity and antibiotics prescriptions associated with two different diagnostic imaging strategies (ultra-low-dose chest computed tomography versus chest radiography)…
- Trial name
- NCT04541160
- Testing
- CR, ULDCT
- Where
- Brazil
- Volunteers
- 237 people
- Sponsor
- Hospital Israelita Albert Einstein
Esophageal Cancer, Lung Cancer
4-Dimensional CT Derived Ventilation Versus SPECT Aerosol Ventilation in Patients With Thoracic Malignancies
Objectives: Primary Objective: 1. To determine the correlation between 4-dimensional computed tomography (4D CT) derived ventilation and single photon emission tomography (SPECT) aerosol Tc-99m determined ventilation.
- Trial name
- NCT00531180
- Testing
- 4D CT scans, Lung Function Imaging
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- M.D. Anderson Cancer Center
Pulmonary Disease
Chest CT Using Low-concentration Iodine Contrast Media
This study aims to evaluate the quality of images when low-concentration iodine contrast agents is used in chest CT with low tube voltage and if they can be used in routine imaging.
- Trial name
- NCT05967117
- Testing
- Iohexol (320mgI/mL) with 120kVp, Iohexol (320mgI/mL) with 100kVp, Iohexol (270mgI/mL) with 100kVp
- Where
- 6 sites in South Korea
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Jung Im Jung
Lung Cancer, COPD
DEPRECAP: Lung Cancer Screening Programme by LDCT for Patients With COPD or Emphysema.
The DEPRECAP (Early detection of lung cancer) study is an ongoing, prospective, longitudinal, multicenter lung cancer screening program that recruited individuals with COPD or emphysema from the pulmonary clinics of Fundación…
- Conditions
- Lung Cancer, COPD, Emphysema
- Trial name
- DEPRECAP (NCT06690385)
- Where
- 2 sites in Spain
- Volunteers
- 1,998 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Lung Cancer
CT Scans in Screening for Lung Cancer in Current and Former Smokers
RATIONALE: Screening tests, such as CT scanning, may help doctors find cancer cells early and plan better treatment for lung cancer.
- Trial name
- NCT00625690
- Testing
- questionnaire administration, computed tomography, evaluation of cancer risk factors
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Nebraska
Hiatal Hernia, Gastroesophageal Reflux Disease
Intrathoracic Sleeve Migration (Sliding Hiatal Hernia) One Year or More After Laparoscopic Sleeve Gastrectomy
Sleeve gastrectomy is the most commonly performed metabolic bariatric operation. After the operation, the upper part of the gastric sleeve can slide up through the opening in the diaphragm into the chest.
- Conditions
- Hiatal Hernia, Gastroesophageal Reflux Disease, Obesity, Postoperative Complications
- Trial name
- NCT07902895
- Testing
- Laparoscopic sleeve gastrectomy, CT of the thorax and abdomen with oral water-soluble contrast
- Where
- Egypt
- Volunteers
- 61 people
- Sponsor
- Kasr El Aini Hospital
Breast Cancer Female
Breast Lesion in CT Chest
The aims of this study are To evaluate the CT features of incidental breast lesions on chest CT and subsequently suggest useful criteria for referral to a specialized breast unit.
- Trial name
- NCT06196216
- Testing
- MSCT
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Unspecified Adult Solid Tumor, Protocol Specific
Computed Tomography in Detecting Movement of the Esophagus in Patients Undergoing Radiation Therapy to the Chest
RATIONALE: Comparing results of diagnostic procedures, such as computed tomography scan (CT scan), done before and after radiation therapy to help detect movement of the esophagus may help doctors plan the best treatment.
- Trial name
- NCT00433524
- Testing
- computed tomography
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Fox Chase Cancer Center
Coronary Artery Disease, Chest Pain
Effects of Heart Imaging Radiation on DNA Double-Stranded Breaks in Blood Lymphocytes and Hair Follicle Cells
Purpose 1. To investigate the effects of cardiac imaging radiation on the induction of DNA double-strand breaks by enumerating gamma-H2AX foci in blood lymphocytes and plucked hair follicle cells. 2.
- Trial name
- NCT02617888
- Testing
- CCTA ~ BREAST SHIELDS
- Volunteers
- 228 people
- Sponsor
- Walter Reed National Military Medical Center
Coronary Angiography, Chest Pain
Coronary Computed Tomography for Systematic Triage of Acute Chest Pain Patients to Treatment (CT-STAT)
This is a prospective, randomized multicenter trial comparing MSCT to standard of care (SOC) diagnostic treatment in the triage of Emergency Department (ED) low to intermediate risk chest pain patients.
- Trial name
- CTSTAT (NCT00468325)
- Testing
- Multi-slice computed tomography, Rest-stress Nuclear Myocardial Perfusion Imaging
- Where
- 16 sites in United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Copd, Emphysema
Exploring Novel Biomarkers for Emphysema Detection
The goal of this clinical trial is to evaluate whether voice or capnometry, alone or in combination with other (non invasive) biomarkers can be used to detect emphysema on chest CT-scan in people with chronic obstructive…
- Trial name
- ENBED (NCT05825261)
- Testing
- voice sampling, capnometry
- Where
- 2 sites in Netherlands
- Volunteers
- 200 people
- Sponsor
- Maastricht University
2019-nCoV (COVID-19), Interstitial Pneumonia
Interest of the Use of Pulmonary Ultrasound in the Referral of Patients With or Suspected COVID-19 +
The recent pandemic due to the SARS-CoV2 results in a pulmonary infection in major symptomatic patients. Because of the large number of patients and the risk of acute respiratory distress syndrome (which seems to occur in almost…
- Trial name
- eChoVid (NCT04335019)
- Testing
- Pulmonary ultrasound
- Where
- France
- Volunteers
- 328 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris