Clinical trials: Chest CT Scan
Coronary Artery Disease (CAD)
Improved Management of Patients With Recent-Onset Stable Chest Pain
In Germany, coronary CT offers an accurate and less burdensome alternative to cardiac catheterisation for evaluating suspected coronary artery disease, but it is still underused.
- Trial name
- IMPRO (NCT07476040)
- Testing
- IMPRO - Cross-Sectoral Care Model for Coronary Diagnostics
- Where
- 39 sites in Germany
- Volunteers
- 3,369 people
- Sponsor
- Philipps University Marburg
Chronic Kidney Disease, Pulmonary Embolism
Safety of Low Dose IV Contrast CT Scanning in Chronic Kidney Disease
The purpose of this study is to show that the use of low volume iso-osmolar non-ionic radio contrast medium (30 cc) in a thoracic CT Scanning procedure in a selected group of patients with chronic kidney disease (CKD) will avoid…
- Conditions
- Chronic Kidney Disease, Pulmonary Embolism, Renal Artery Stenosis, Pulmonary Cancer
- Trial name
- NCT02476526
- Testing
- Low Volume iso-osmolar non-ionic radio contrast medium, Acetylcysteine Inhalation, Sodium Bicarbonate Solution
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Greater Los Angeles Healthcare System
Acute Respiratory Distress Syndrome, Mechanical Ventilation Complication
Early Diagnosis of ARDS in Mechanically Ventilated Patient Using LUS Score in Comparison With CT
The aim of this study is to assess accuracy of Lung ultrasound score for early diagnosis of acute respiratory distress syndrome in patients who expected to be mechanically ventilated more than 24 hour in comparison with computed…
- Conditions
- Acute Respiratory Distress Syndrome, Mechanical Ventilation Complication, Computed Tomography
- Trial name
- NCT06971042
- Testing
- Lung Ultrasound
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
Chronic Obstructive Pulmonary Disease, Pulmonary Emphysema
Volumetric HRCT in Stable COPD Patients.
This study evaluates the role of volumetric high-resolution computed tomography (HRCT) of the chest in assessing patients with stable chronic obstructive pulmonary disease (COPD).
- Conditions
- Chronic Obstructive Pulmonary Disease, Pulmonary Emphysema, Airway Obstruction
- Trial name
- NCT07809399
- Testing
- Volumetric HRCT chest, Spirometry and Body Plethysmography
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Mansoura University
Chest Pain, Acute Coronary Syndrome
Computed Tomography Coronary Angiogram (CTCA) Versus Traditional Care in Emergency Department Assessment of Potential Acute Coronary Syndromes (ACS)
This multi-center, randomized, controlled trial conducted in Emergency Departments (ED) compares computed tomography (CT) coronary angiography with the traditional approach (usual care) for low- to intermediate-risk chest pain…
- Conditions
- Chest Pain, Acute Coronary Syndrome, Acute Myocardial Infarction, Coronary Artery Disease
- Trial name
- NCT00933400
- Testing
- CT Coronary Angiography (CTCA), Traditional Strategy
- Where
- 5 sites in United States
- Volunteers
- 1,392 people
- Sponsor
- American College of Radiology
Chronic Obstructive Pulmonary Disease, Cardiovascular Diseases
An Open Prospective Longitudinal Pulmonary-cardiovascular Cohort Study
This is an observational study aiming to identify and validate biomarkers (including imaging and clinical descriptors) for chronic obstructive pulmonary disease (COPD), cardiovascular disease (CVD) and lung cancer.
- Conditions
- Chronic Obstructive Pulmonary Disease, Cardiovascular Diseases, Lung Cancer
- Trial name
- BIG3 (NCT01460264)
- Where
- Sweden
- Volunteers
- 10,000 people
- Sponsor
- Region Skane
Asthma (Diagnosis), COPD (Chronic Obstructive Pulmonary Disease)
Quantitative Chest CT and Multi-Omics to Distinguish Asthma From COPD and Predict Treatment Response
This study aims to improve the diagnosis and treatment prediction of asthma and chronic obstructive pulmonary disease (COPD) by combining quantitative chest computed tomography (CT) imaging with multi-omics data.
- Trial name
- CTOMICS (NCT07602192)
- Where
- 2 sites in South Korea
- Volunteers
- 200 people
- Sponsor
- Korea University Guro Hospital
Non Small Cell Lung Cancer
Evaluation of Preoperative Endobronchial Ultrasound (EBUS) in Non Small Cell Lung Cancer (NSCLC)
This study aims to assess both the role and cost-effectiveness of EBUS in preoperative Non small cell lung cancer staging. This controlled multicentric study will be conducted in 22 centers in France.
- Trial name
- EVIEPEB (NCT00960271)
- Testing
- EBUS
- Where
- France
- Volunteers
- 363 people
- Sponsor
- University Hospital, Rouen
Pulmonary Nodules, Lung Neoplasms
Longitudinal AI-Assisted Management of Indeterminate Pulmonary Nodules
Patients with indeterminate lung nodules often face a choice between continued CT surveillance and invasive investigation. This trial compares management with or without access to an AI report that matches nodules across real…
- Trial name
- NCT07895277
- Testing
- AI-Assisted Longitudinal CT Assessment and Pulmonary Nodule Management
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Coronary Artery Disease
Safety and Cost-efficiëncy of New Imaging Techniques in Patients Suspected of Coronary Artery Disease
Yearly, 180 000 patients in the Netherlands are referred to a cardiologist with symptoms suspected of coronary artery disease (CAD). To assess this, multiple diagnostic tests are available.
- Trial name
- iCORONARY (NCT04939207)
- Testing
- CT-FFR, Angiography-derived FFR, Angiography with invasive FFR-measurements
- Where
- 4 sites in Netherlands
- Volunteers
- 825 people
- Sponsor
- St. Antonius Hospital
Angina
The Addition of Cardiac CT to Exercise Treadmill Testing in the Evaluation of Angina
The current outpatient evaluation for angina in low and intermediate risk patients typically starts with a functional assessment for coronary ischemia.
- Trial name
- CT-EXTRA (NCT00491218)
- Where
- United States
- Sponsor
- Walter Reed Army Medical Center
Lung Cancer
Image Discovering Early Lung Cancer Project
Lung cancer is the leading cause of cancer related death in Taiwan and world wide. The application of low dose helical computed tomography (CT) has been the milestone of lung cancer screening.
- Trial name
- IDEALCAP (NCT01914458)
- Testing
- Low-dose computed tomography (LDCT)
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Cathay General Hospital
Pneumonia
Role of Chest Ultrasound in Diagnosing and Follow-up of Pneumonia
The study of a large number of patients (at least 200 patients) from several European centres aims to investigate the value of chest ultrasound in diagnosing and checking the course of pneumonia as compared to a chest X-ray film…
- Trial name
- NCT00808457
- Where
- Germany
- Volunteers
- 397 people
- Sponsor
- University of Jena
Coronary Stenosis, Acute Coronary Syndrome
Coronary Plaque Geometry and Acute Coronary Syndromes
The aim of GEOMETRY study is to investigate the correlation between coronary plaque geometric modifications and lesion vulnerability in patients with suspected coronary artery disease referred for cardiac computed tomography…
- Conditions
- Coronary Stenosis, Acute Coronary Syndrome, Acute Myocardial Infarction, Atherosclerosis
- Trial name
- NCT03702764
- Testing
- CCTA
- Where
- Romania
- Volunteers
- 1,000 people
- Sponsor
- Cardio Med Medical Center
COVID-19
Impact of the CT Scan in Patients With Suspected Covid-19
The diagnostic performance of the scanner in the indication of suspected Covid-19 is not yet well known, especially in comparison with the results of RT-PCR.
- Trial name
- SCAN-COV-HUS (NCT05079191)
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Strasbourg, France
Angina, Chest Pain
Transmyocardial Laser Revascularization and Cardiovascular Magnetic Resonance Imaging
The primary goal of this study is to better understand how Transmyocardial Laser Revascularization (TMR) affects the functioning of the heart and, in turn, relieves angina in individuals with coronary heart disease using Magnetic…
- Trial name
- Amsterdam (NCT01287910)
- Testing
- Cardiac MRI
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Piedmont Healthcare
Lung Cancer, Pneumothorax
Effectiveness of the Autologous Blood Patch Method in Lung Biopsies
In this retrospective study, investigators aimed to evaluate the effectiveness of the autologous blood patch method in percutaneous transthoracic lung biopsies performed with the coaxial technique.
- Trial name
- NCT05904574
- Testing
- Autologous blood patch, Percutaneous transthoracic biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Trakya University
Lung Cancer
ARtificial Intelligence for Gross Tumour vOlume Segmentation
Identifying the outline of a Gross Tumour Volume (GTV) in lung cancer is an essential step in radiation treatment. Clinical research, such as radiomics and image-based prognostication, requires the GTV to be pre-defined on…
- Trial name
- ARGOS (NCT05775068)
- Testing
- Radiotherapy
- Where
- Netherlands
- Volunteers
- 2,000 people
- Sponsor
- Maastricht Radiation Oncology
Mycobacterium Infections, Nontuberculous
Diagnostic Accuracy of Nontuberculous Mycobacterial Lung Disease Based on Chest CT
The aim of this study was to elucidate the accuracy and inter-rater agreement of diagnosis of nontuberculous mycobacterial lung disease based on chest computed tomography findings.
- Trial name
- NCT02340897
- Volunteers
- 132 people
- Sponsor
- Seoul National University Hospital
Pulmonary Embolism
External Validation of a Deep Learning Based Model for Pulmonary Embolism Detection on Chest CT Scans
The scope of this study is the external validation of an explainable deep learning-based classifier for the diagnosis and detection of pulmonary embolism in computed tomography pulmonary angiography (CTPA) and contrast enhanced…
- Trial name
- NCT05333042
- Where
- Belgium
- Volunteers
- 5,000 people
- Sponsor
- OncoRadiomics