Clinical trials: Chest Infection
Lower Respiratory Tract Infections
Lung Sounds as Indicators of Severity and Recovery of Lung Disease
This study aims to assess the responsiveness to change of adventitious lung sounds (ALS) in patients with lower respiratory tract infection (LRTI).
- Trial name
- NCT02053870
- Testing
- Physiotherapy+conventional treatment, Conventional treatment
- Where
- Portugal
- Volunteers
- 98 people
- Sponsor
- Aveiro University
Cancer
External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Indinavir and ritonavir may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
- Trial name
- NCT00637637
- Testing
- indinavir sulfate, ritonavir, radiation therapy
- Where
- 3 sites in Switzerland
- Volunteers
- 60 people
- Sponsor
- Oncology Institute of Southern Switzerland
Lung Cancer, Lymphoma
Collecting and Studying Tissue Samples From Patients With HIV-Associated Malignancies
RATIONALE: Collecting and studying tissue samples from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT01567722
- Testing
- DNA analysis, RNA analysis, gene expression analysis
- Where
- 14 sites in United States
- Volunteers
- 114 people
- Sponsor
- AIDS Malignancy Consortium
Lung Cancer in the HIV Patient, HIV Infections
Screening for Lung Cancer in the HIV Patient
That computed tomography (CT) screening of HIV-seropositive heavy smokers will detect early stage lung cancer at significantly higher rates than what is currently being observed.
- Conditions
- Lung Cancer in the HIV Patient, HIV Infections, HIV Seropositivity, Lung Cancer
- Trial name
- NA_00036809 (NCT01748136)
- Testing
- CT Scan with Spirometry
- Volunteers
- 200 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Sternal Wound Infection, Mediastinitis
Rapid Sternal Closure System (TALON)
The primary objective is to establish if the Rapid Sternal Closure System (RSCS) improves early postoperative recovery as manifested by decreased pain and improved pulmonary function.
- Trial name
- TALON (NCT00638014)
- Testing
- Rapid Sternal Closure System, Conventional wire closure
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Duke University
Lower Respiratory Tract Infection
Procalcitonin and Lung Ultrasonography Guided Antibiotherapy in Emergency Departments
Acute respiratory infections are a common reason of attendance at emergency departments. It is also the main reason of unnecessary antibiotic prescription.
- Trial name
- PLUS-IS-LESS (NCT05463406)
- Testing
- The PLUS algorithm, Usual care
- Where
- 9 sites in Switzerland
- Volunteers
- 1,407 people
- Sponsor
- Dr Boillat-Blanco Noemie
Pneumonitis, Nonsmall Cell Lung Cancer Stage III
Exhaled Breath Analysis to Predict Risk of Symptomatic Pneumonitis
This is a prospective pilot study investigating exhaled breath condensate analyses to quantify the variability over time of various biomarkers associated with symptomatic pneumonitis.
- Trial name
- NCT04040244
- Testing
- Exhaled Breath Collection, Blood sample
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Wake Forest University Health Sciences
Cervical Cancer, Microsatellite Instability (MSI)-High Endometrial Cancer
A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies
The purpose of this study is to determine the safety, tolerability, and preliminary efficacy of INCAGN02385 in participants with advanced malignancies.
- Conditions
- Cervical Cancer, Microsatellite Instability (MSI)-High Endometrial Cancer, Gastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ]), Esophageal Cancer
- Trial name
- NCT03538028
- Testing
- INCAGN02385
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- Incyte Biosciences International Sàrl
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Lung Cancer, Emphysema
CryoSpray Ablation(tm)Thoracic Patient Registry
The purpose of this study is to create a patient registry to collect and analyze information on subjects treated with the CryoSpray Ablation™ System post-510K approval.
- Conditions
- Lung Cancer, Emphysema, Chronic Bronchitis, COPD
- Trial name
- NCT00785239
- Sponsor
- CSA Medical, Inc.
Tuberculosis, Lower Respiratory Infection
Host Blood RNA Signatures for Diagnosis of TB
Tuberculosis (TB) is the biggest infectious cause of death worldwide, and the biggest cause of death in Sub-Saharan Africa among HIV-positive patients.
- Trial name
- RADIANT (NCT05542511)
- Where
- South Africa
- Volunteers
- 1,458 people
- Sponsor
- University of Stellenbosch
COVID-19 Respiratory Infection, Parkinson Disease
Chest Mobility, Strength, Physical Activity and Quality of Life in Parkinson's Patients With Post-COVID-19
To comparative pain intensity, chest mobility, cough strength, muscle strength, physical activity levels and quality of life in Parkinson's patients with post-COVID-19 and without post-COVID-19 was aimed in current study.
- Trial name
- NCT06008444
- Testing
- Physical Evaluations of post-COVID-19 individuals, Physical Evaluations of non-post-COVID-19 individuals
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Izmir Democracy University
Pneumonia, COPD
Feasibility of a Physical Therapy Intervention on Older Adults With Hyperkyphosis or Forward Head Posture
The original intent was to use a manual therapy and therapeutic exercise intervention with older patients with pneumonia post-hospitalization.
- Conditions
- Pneumonia, COPD, Hyperkyphosis, Postural, Thoracic Kyphosis
- Trial name
- NCT04114331
- Testing
- Manual therapy and exercise
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Tuberculosis, Pulmonary, Non-Tuberculous Mycobacterial Pneumonia
Microbiome in Pulmonary Tuberculosis, Non-tuberculous Mycobacterial Pulmonary Diseases, Lung Cancer and Hemoptysis
Microbiome in lower respiratory diseases is not sufficiently known yet. The objective of this study is to investigate microbiome in patients who present with hemoptysis, and those with pulmonary tuberculosis, non-tuberculous…
- Conditions
- Tuberculosis, Pulmonary, Non-Tuberculous Mycobacterial Pneumonia, Lung Cancer, Hemoptysis
- Trial name
- NCT04079400
- Volunteers
- 43 people
- Sponsor
- Gachon University Gil Medical Center
Bronchiolitis
Clinical Evaluation of the Response to Chest Physiotherapy in Children With Acute Bronchiolitis
The objective of this study is to evaluate the clinical response of children diagnosed with acute bronchiolitis, relative to a chest physiotherapy protocol.
- Trial name
- FIBARRIX (NCT02458300)
- Testing
- Nebulization of hypertonic saline, Prolonged slow expiration technique (PSE), Patient coughing Provocation (TP)
- Volunteers
- 77 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Stroke, Pneumonia
Pulmonary CT in Pneumonia Complicating Stroke
Pneumonia commonly complicates stroke and has a profound impact on clinical outcomes. Accurate and timely diagnosis of pneumonia complicating stroke remains a major challenge as several issues potentially confound diagnosis.
- Trial name
- NCT03106909
- Testing
- pulmonary computed tomography (CT)
- Where
- 2 sites in United Kingdom
- Volunteers
- 41 people
- Sponsor
- Natalie Garratt
Tuberculosis, Thoracic Surgery
Study of TB Lesions Obtained in Therapeutical Surgery
The correlation of the morphologic, microbiological, genetic and histopathological characteristics of TB lesions obtained in therapeutical surgery with the clinical forms and features of the patients will provide essential…
- Conditions
- Tuberculosis, Thoracic Surgery, Tuberculosis, Pulmonary, Tuberculosis, Multidrug-Resistant
- Trial name
- SH-TBL (NCT02715271)
- Testing
- therapeutical surgery for TB
- Where
- Georgia
- Volunteers
- 192 people
- Sponsor
- Fundació Institut Germans Trias i Pujol
Angina, Acute Bronchiolitis
Impact of a Multimodal Intervention on Antibiotic Prescribing for Respiratory Infections in Primary Care
Antimicrobial resistance (AMR), considered one of the greatest global threats by the WHO, justifies the development of initiatives to promote appropriate antibiotic use-especially in primary care, where most antibiotics in France…
- Conditions
- Angina, Acute Bronchiolitis, Acute Bronchitis, COPD Exacerbation (AECOPD)
- Trial name
- GRASP (NCT07359287)
- Testing
- Antibiotic prescribing according to guidelines
- Where
- France
- Volunteers
- 4,500 people
- Sponsor
- University Hospital, Caen
Tracheitis, Tracheobronchitis
Evaluation of the Treatment With Klacid®SR in Patients With Lower Respiratory Tract Infection
The aim of this post-marketing observational study (PMOS) is to describe the relief of symptoms, tolerability and compliance of treatment with Klacid®SR in a dose 1000 mg once daily in patients with lower respiratory tract…
- Conditions
- Tracheitis, Tracheobronchitis, Bronchitis, Chronic Bronchitis
- Trial name
- NCT01108185
- Where
- 158 sites in Slovakia
- Volunteers
- 3,181 people
- Sponsor
- Abbott
Adenovirus, Anesthesia
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Understudied drugs will be administered to children per standard of care as prescribed by their treating caregiver and only biological sample collection during the time of drug administration will be involved.
- Conditions
- Adenovirus, Anesthesia, Anxiety, Anxiolysis
- Trial name
- PTN_POPS (NCT01431326)
- Testing
- The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada and 3 more
- Volunteers
- 3,520 people
- Sponsor
- Daniel Benjamin