Clinical trials: Chest Pain
Coronary Artery Disease
An Epidemiological Cohort Study of Acute Coronary Syndromes in The Greek Population. The PHAETHON Study
A nationwide registry of patients with acute coronary disease to evaluate epidemiological patient characteristics, medical management, implementation of invasive strategy, patient outcome and impact on quality of life in Greece.
- Trial name
- PHAETHON (NCT02420808)
- Where
- Greece
- Volunteers
- 800 people
- Sponsor
- Hellenic Cardiovascular Research Society
Coronary Artery Disease, Angina Pectoris
Clinician Utilization of Corus CAD (or ASGES) in Primary Care Provider Decision Making
This retrospective study will investigate clinician behavior in diagnosing patients with possible obstructive coronary artery disease who received a Corus CAD (Age/Sex/Gene Expression score - ASGES) result compared to patients…
- Conditions
- Coronary Artery Disease, Angina Pectoris, Chest Pain, Cardiovascular Diseases
- Trial name
- CU-PCP (NCT02158754)
- Testing
- Corus CAD (ASGES)
- Where
- 9 sites in United States
- Sponsor
- CardioDx
Pain, Postoperative, Multimodal Analgesia
Comparison of the Rhomboid Intercostal Block and Serratus Posterior Superior Intercostal Plane Block
Video-assisted thoracic surgery (VATS) is widely performed for the management of various thoracic pathologies and is generally associated with reduced surgical trauma compared with open thoracotomy.
- Conditions
- Pain, Postoperative, Multimodal Analgesia, Rhomboid Intercostal Block, Serratus Posterior Superior Intercostal Plane Block
- Trial name
- NCT07650877
- Testing
- Rhomboid Intercostal Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara City Hospital Bilkent
Stable Angina
Comparison of Vascular Remodeling Between Different Antianginal Medication Evaluated by Noninvasive ECG-gated Fundus Photographic Evaluation
Treatments for stable angina includes drug therapy such as calcium-channel blocker, beta blocker, and ACEI/ARB. To obtain good prognosis in patients with coronary artery disease,preventing or correcting the progression of…
- Trial name
- NCT01162902
- Testing
- Diltiazem treated group, Bisoprolol treated group, Candesartan treated group
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Hospital
Stable Angina, Acute Coronary Syndrome
Relationship Between Fractional Flow Reserve/ Instantaneous Wave Free Ratio and Endothelial Wall Shear Stress
This study, designed as a retrospective registry, aims to investigate the relationship and potential interplay between fractional flow reserve (FFR) or instantaneous waves free ratio (iFR) with wall shear stress (WSS) in the…
- Conditions
- Stable Angina, Acute Coronary Syndrome, Coronary Artery Disease
- Trial name
- RELATE (NCT04048005)
- Testing
- Fractional flow reserve
- Where
- 3 sites in Italy
- Volunteers
- 200 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Neck Pain
Effects of Thrust Versus Non-Thrust Thoracic Manipulation on Mechanical Neck Pain.
Neck pain ranks as the 4th leading cause of disability, with high prevalence of mechanical neck pain in young population. As high as 30% of %.
- Trial name
- NCT05542875
- Testing
- Thrust Manipulation, Non-Thrust manipulation, Standard Treatment
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Foundation University Islamabad
Chest Pain
Use of Echocardiography in the Evaluation of Chest Pain in the Emergency Department
Chest pain is one of the most common complaints that brings a patient to the emergency department (ED). The differential diagnosis of chest pain is broad and includes cardiac as well as non-cardiac diseases.
- Trial name
- NCT01125072
- Testing
- Echocardiography with strain analysis
- Where
- United States
- Sponsor
- NYU Langone Health
Foot Reflexology
Effect of Foot Reflexology on Pain Associated With Mediastinal Chest Drain Removal
Cardiovascular diseases (CVDs) remain the leading cause of death worldwide and significantly affect patient quality of life and socioeconomic status.
- Trial name
- NCT05631522
- Testing
- foot reflexology
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Myocardial Infarction, Angina, Unstable
Novel Method to Diagnose Acute Myocardial Ischemia
The aim of this study is to improve the detection of heart attack in people who come to a hospital emergency room (ER) with cardiac symptoms.
- Conditions
- Myocardial Infarction, Angina, Unstable, Myocardial Ischemia, Coronary Disease
- Trial name
- NCT00285922
- Where
- United States
- Volunteers
- 1,320 people
- Sponsor
- University of California, San Francisco
Back Pain
Effects of Cervicothoracic Mobility Program on Low Back Pain
The study will be a randomized control trial to determine the effects of the cervicothoracic mobility program on pain, range of motion, and function in patients with chronic back pain.
- Trial name
- NCT05347251
- Testing
- Cervicothoracic mobility program, Conventional Treatment
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Nociceptive Pain
Cervical/Thoracic Neuromodulation and Nociceptive Processing
Several studies have demonstrated that direct currents delivered through the skin at the level of the low-thoracic spinal cord can influence spinal cord function.
- Trial name
- MICROVOLT2 (NCT06367777)
- Testing
- cervical a-tsDCS, thoracic a-tsDCS
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Coronary Artery Disease, Stable Angina
Randomized Controlled Study of the Traditional Percutaneous Coronary Intervention and Intervention Using Optical Coherence Tomography of Incomplete Stent Adhesion and Extent of the Formation of Neointima by Resolute Zotarolimus-eluting Stent Insertion
Optical coherence tomography (OCT) after the stent procedure to improve the adhesion and expansion, or incomplete uncovered struts attached to the main track.
- Conditions
- Coronary Artery Disease, Stable Angina, Unstable Angina
- Trial name
- NCT01869842
- Testing
- percutaneous coronary intervention, OCT-guided percutaneous coronary intervention
- Where
- South Korea
- Volunteers
- 115 people
- Sponsor
- Yonsei University
Acute Coronary Syndrome:, Non ST Elevation Myocardial Infarction
Assessment of Coronary Flow Reserve by Doppler Flow Wire in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention Differences Between the Loading Dose of Ticagrelor and Clopidogrel
The administration of these drugs is realized according to the European Society of Cardiology guidelines. All patients will be pretreated with aspirin 300 mg orally, heparin iv to maintain an activated clotting time of >250 sec…
- Conditions
- Acute Coronary Syndrome:, Non ST Elevation Myocardial Infarction, ST Elevation Myocardial Infarction, Unstable Angina
- Trial name
- NCT02032290
- Testing
- Assessment of Coronary Flow Reserve, Percutaneous coronary intervention, ticagrelor loading
- Where
- Italy
- Volunteers
- 88 people
- Sponsor
- Azienda Policlinico Umberto I
Acute Coronary Syndrome, Depression
MBCT Delivered Via Group Videoconferencing for ACS Syndrome Patients With Depressive Symptoms
Brief Summary: The aim of this study is to explore the initial feasibility and acceptability of (a) Mindfulness-Based Cognitive Therapy (MBCT) adapted for ACS patients; (b) the group videoconferencing delivery medium; and (c)…
- Conditions
- Acute Coronary Syndrome, Depression, Myocardial Infarction, Unstable Angina
- Trial name
- NCT04231097
- Testing
- MBCT intervention for ACS patients
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Massachusetts General Hospital
Paresthesia, Dysesthesia
Sensory Mapping Following Video-assisted Thoracic Surgery
This is a prospective observational cohort study on changes in sensory mapping.
- Conditions
- Paresthesia, Dysesthesia, Pain
- Trial name
- NCT01375283
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acupuncture, Pain Control
Acupuncture in Postoperative Pain Control for Minimal Invasive Thoracoscopic Surgery Patients
Minimal invasive thoracoscopic surgery has been used widely for common thoracic diseases in recent years. Patients who received thoracoscopic surgery recovered much quickly and returned to their daily life sooner because of small…
- Conditions
- Acupuncture, Pain Control, Randomized Controlled Trial, Thoracic Surgery
- Trial name
- NCT02959346
- Testing
- Acupuncture
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- China Medical University Hospital
Angina Pectoris
Absorption and Pharmacokinetics of Nitroglycerin to a New Formulation
The study evaluate the absorption rate of different sublingual formulation of nitroglycerine (NTG) either in the form of available tablets or a new rapid absorbable gelation capsule formulation "NTG1523" by determining T-max and…
- Trial name
- NCT03777605
- Testing
- Nitroglycerin 0.4 MG
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Kolding Sygehus
Stable Angina Pectoris
Prevalence and Prognostic Value of Unrecognized Myocardial Injury in Stable Coronary Artery Disease (PUMI)
This study includes patients with stable coronary artery disease without previously known myocardial infarction, and investigates the prevalence of clinically unrecognized myocardial damage and its prognostic implication.
- Trial name
- PUMI (NCT01257282)
- Where
- 6 sites in Sweden
- Volunteers
- 275 people
- Sponsor
- Uppsala University
Postoperative Pain, Thoracic Cancer
Ultrasound-guided Block for Thoracic Surgery Pain
The investigators aimed to assess Ultrasounde- guided serratus anterior plane block can be effective in acute postoperative pain following thoracic surgery.
- Trial name
- NCT03240562
- Testing
- serratus anterior plane block, patient controlled analgesia
- Where
- South Korea
- Volunteers
- 89 people
- Sponsor
- Samsung Medical Center
Lung Cancer
Investigation of Cannabis for Pain and Inflammation in Lung Cancer
Radiation therapy to the chest is used in late stage lung cancer, and it often leads to inflammation of the esophagus. The inflammation is expected to occur in about 75% of patient, and usually begin within a week of starting…
- Trial name
- NCT02675842
- Testing
- Smoked Cannabis High CBD/low THC
- Sponsor
- New York State Psychiatric Institute