Clinical trials: Chest Pains
Neck Pain
Cervical and Upper Thoracic Mobilization and Manipulation for Mechanical Neck Pain
The objective of this pilot study is to determine the feasibility of a large-scale trial. The primary objective is to determine if manipulation applied to the cervical and thoracic spines is more effective than mobilization…
- Trial name
- NCT02036905
- Testing
- Cervical and thoracic mobilization, cervical and thoracic manipulation
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Youngstown State University
Microvascular Angina, Angina Pectoris
Coronary Microvascular Angina Cardiac Magnetic Resonance Imaging (CorCMR) Trial
Anginal symptoms due to ischaemia with no obstructive coronary arteries (INOCA) is a common clinical problem, however, diagnosis and onward management is heterogeneous, and prognosis is affected.
- Conditions
- Microvascular Angina, Angina Pectoris, Angina, Stable, Non-Obstructive Coronary Atherosclerosis
- Trial name
- CorCMR (NCT04805814)
- Testing
- CMR results disclosed, CMR performed but results not disclosed
- Where
- 3 sites in United Kingdom
- Volunteers
- 280 people
- Sponsor
- NHS National Waiting Times Centre Board
Breast Cancer, Cognitive/Functional Effects
Study of Symptoms Caused by Cancer and Cancer Therapy in Patients With Invasive Breast, Lung, Prostate, or Colorectal Cancer
RATIONALE: Questionnaires that assess symptoms caused by cancer and cancer therapy may help improve the ability to plan treatment for patients with invasive cancer to help them live longer and more comfortably.
- Conditions
- Breast Cancer, Cognitive/Functional Effects, Colorectal Cancer, Lung Cancer
- Trial name
- NCT00303914
- Testing
- assessment of therapy complications, cognitive assessment, psychosocial assessment and care
- Where
- 32 sites in United States
- Volunteers
- 2,310 people
- Sponsor
- Eastern Cooperative Oncology Group
Chronic Stable Angina
Danhong Injection in the Treatment of Chronic Stable Angina
The purpose of this study is to evaluate the effect of Danhong Injection on the relief of angina with the use of the Seattle Angina Questionnaire among patients with stable angina patients
- Trial name
- NCT01681316
- Testing
- Danhong injection, Standard medical care
- Where
- 31 sites in China
- Volunteers
- 920 people
- Sponsor
- China Academy of Chinese Medical Sciences
Endothelial Dysfunction, Atherosclerosis
Blood Markers for Inflammation and Coronary Artery Vasoreactivity Testing in Patients With Chest Pain and Normal Coronary Arteries
The investigators are hoping to discover the cause of chest pain in patients with a normal coronary arteriogram. For patients with chest pain coronary angiography is the standard method by which the blood vessels of the heart can…
- Conditions
- Endothelial Dysfunction, Atherosclerosis, Inflammation, Myocardial Ischemia
- Trial name
- ACOVA (NCT01162824)
- Testing
- Acetylcholine, Adenosine
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- St George's Healthcare NHS Trust
Stable Angina Pectoris
Cardiogoniometry for Early Diagnosis of Coronary Artery Disease Symptomatik
The register study CGM@CAD will examine whether cardiogoniometry can provide additional information concerning the indication for a diagnostic coronary angiography and if so, which additional value it has.
- Trial name
- NCT01174680
- Testing
- cardiogoniometry
- Volunteers
- 43 people
- Sponsor
- Stiftung Institut fuer Herzinfarktforschung
Foot Reflexology
Effect of Foot Reflexology on Pain Associated With Mediastinal Chest Drain Removal
Cardiovascular diseases (CVDs) remain the leading cause of death worldwide and significantly affect patient quality of life and socioeconomic status.
- Trial name
- NCT05631522
- Testing
- foot reflexology
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Coronary Artery Disease, Angina Pectoris
Lesional Evaluation of High Risk Patients With Neoatherosclerosis Treated With Rosuvastatin and Eicosapentaenoic Acid Using Optical Coherence Tomography(OCT)[LINK IT TWO]
This study aim is to evaluate the additional effect of eicosapentaenoic acid and dose up effect of rosuvastatin for neoatherosclerosis in coronary artery disease patients.
- Trial name
- NCT03657758
- Testing
- EPA and rosuvastatin, High dose rosuvastatin
- Where
- Japan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kobe University
ST Segment Elevation Myocardial Infarction, Non-ST Segment Elevation Myocardial Infarction
Cardiac Care Solution for Coronary Disease Follow up
This is a prospective, randomized controlled trial. The aim of the study is to evaluate the impacts of a cardiac post-discharge management solution in the secondary prevention of Coronary Artery Disease (CAD).
- Conditions
- ST Segment Elevation Myocardial Infarction, Non-ST Segment Elevation Myocardial Infarction, Unstable Angina
- Trial name
- BAMA (NCT03565978)
- Testing
- BAMA solution
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University First Hospital
Refractory Angina
Cardiac Rehabilitation in Patients With Refractory Angina
The purpose of this study is to evaluate the safety and feasibility of cardiovascular rehabilitation in Patients with refractory angina, evaluate the effect of cardiovascular rehabilitation in patients with angina Refractory, by…
- Trial name
- NCT03218891
- Testing
- Cardiac Rehabilitation
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Stable Angina, Unstable Angina Pectoris
Opsens Optowire for Fractional Flow Reserve - The O2 Pilot Study
The purpose of this study is to assess the usability and safety of the Opsens OptoWire and Optomonitor in measuring fractional flow reserve (FFR) in patients with coronary artery disease who are undergoing a coronary angiogram.
- Conditions
- Stable Angina, Unstable Angina Pectoris, Chest Pain, Ischemia
- Trial name
- O2 (NCT02144090)
- Testing
- Fractional flow reserve measurement
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Laval University
Angina Exacerbation Acute
Effects of Low Frequency Magnetic Field on Exercise Induced Angina
The investigators have previously shown that a frequency of 15.95-16.00 Hz protects against acute myocardial infarction in rats.
- Trial name
- NCT01423422
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Aerotel Ltd
Postoperative Pain Management, Radical Cystectomy
Early Postoperative Administration of Oxycodone +/- Naloxone and Duration of Epidural Analgesia
Cystectomy with urinary diversion (ileal conduit, ileal orthotopic neobladder, catheterizable ileal pouch) is major abdominal surgery, which is associated with a high incidence of gastrointestinal complications.Perioperative…
- Conditions
- Postoperative Pain Management, Radical Cystectomy, Epidural Analgesia, Oral Oxycodone With/Without Naloxone
- Trial name
- NCT02516059
- Testing
- oxycodone/naloxone, Oxycodone, epidural catheter
- Where
- Switzerland
- Volunteers
- 90 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Unstable Angina
Research on the Clinical Effect of Shuanghe Decoction in Treating Unstable Angina.
This study evaluates the clinical efficacy of Shuanghe Decoction in the treatment of unstable angina. All of the patients will be divided into 2 arms randomly.
- Trial name
- NCT03179527
- Testing
- Anti-Platelet Drugs, Lipid Regulating Drugs, Coronary Vasodilator
- Volunteers
- 120 people
- Sponsor
- Jun Li
Thoracic Diseases, Analgesia
Comparison of Tramadol, Pethidine and Morphine in the Treatment of Pain After Thoracic Surgery
Comparison of analgesic effects of tramadol, aldolan and morphine under thoracic surgery
- Trial name
- NCT06172920
- Testing
- Tramadol hydrochloride, Aldolan, Morphine hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Baskent University
Myocardial Infarction, Unstable Angina
Myocardial Ischemia and Transfusion Pilot
The purpose of this study is to evaluate two approaches to red blood cell transfusion in anemic patients with acute coronary syndrome.
- Conditions
- Myocardial Infarction, Unstable Angina, Coronary Artery Disease
- Trial name
- MINT Pilot (NCT01167582)
- Testing
- Red blood cell transfusion
- Where
- 7 sites in United States
- Volunteers
- 110 people
- Sponsor
- Rutgers, The State University of New Jersey
Esophageal Diseases
Investigation of Cannabinoid Receptor Agonist Dronabinol in Patients With Functional Chest Pain
In a recent study, Dronabinol was shown to reduce symptoms in patients with Functional Chest Pain (non-cardiac chest pain). Additionally, metabolic measures and patients' weights were not adversely affected by this regiment.
- Trial name
- ICAMP (NCT02569073)
- Testing
- Dronabinol
- Where
- United States
- Sponsor
- Temple University
Hypercholesterolemia
Study of Efficacy, Safety, Tolerability and Quality of Life of Inclisiran (KJX839) vs Placebo, on Top of Ongoing Individually Optimized Lipid-lowering Therapy, in Participants With Hypercholesterolemia
Study of efficacy, safety, tolerability and quality of life of inclisiran (KJX839) vs placebo, on top of ongoing individually optimized lipid-lowering therapy, in participants with hypercholesterolemia
- Trial name
- V-DIFFERENCE (NCT05192941)
- Testing
- Inclisiran Sodium
- Where
- 136 sites in Bulgaria, Czechia and 6 more
- Volunteers
- 1,770 people
- Sponsor
- Novartis Pharmaceuticals
Emergency Medical Services, Nursing Care
High-Sensitivity Troponin I in Addition to Guideline-Based Care in EMS
The TIGER study is a study investigating the utlility of a point-of-care blood analyse of Troponin I to help identify patients with heart attacks in the prehospital emergency care.
- Conditions
- Emergency Medical Services, Nursing Care, Cardiology, Myocardial Infarction
- Trial name
- TIGER (NCT07008391)
- Testing
- high sensitivity Troponin I
- Where
- Sweden
- Volunteers
- 1,419 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Hyperkyphosis
Thoracic Extension and Global Postural Corrective Exercises on Individuals With Hyper Kyphosis
The study was conducted to compare the effective of thoracic extension exercises and global postural corrective exercises on pain, range of motion and posture among hyperkyphotic individuals.
- Trial name
- NCT07426588
- Testing
- Thoracic Extension Exercises, Global Postural corrective Exercises, Standard Physical Therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
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