Clinical trials: Chest Pains
Chest Pain
Chest Pain Perception and Capsaicin Sensitivity in Patients With Acute Cardiac Ischemia
The purpose of this study is to determine whether there is a positive correlation between the ability to sense chest pain in the context of myocardial ischemia and the ability to sense discomfort associated with the topical…
- Trial name
- NCT02346916
- Testing
- Capsaicin
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Bassett Healthcare
Chronic Stable Angina
Phase II Study of STA-2 in Patients With Chronic Stable Angina
The objectives of this study are to evaluate the efficacy, pharmacological activities and safety of STA-2 in the treatment of chronic stable angina.
- Trial name
- NCT01484912
- Testing
- STA-2
- Where
- 3 sites in Taiwan
- Volunteers
- 79 people
- Sponsor
- Sinphar Pharmaceutical Co., Ltd
Acute Chest Pain
Early Cardiac Computed Tomography (CT) In Patients Admitted With Acute Chest Pain
This is a randomised trial comparing early Cardiac Computed Tomography (CCT) to current standard practice for diagnosis of acute chest pain in patients at low to intermediate risk of having coronary artery disease (CAD), in a UK…
- Trial name
- EXACCT (NCT00767065)
- Testing
- Cardiac Computed Tomography, Standard care
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Coronary Artery Disease, Myocardial Ischemia
Feasibility Study of the Amaranth Medical FORTITUDE Bioresorbable Drug-Eluting Coronary Stent
The purpose of this study is to evaluate the safety and feasibility of a new coronary artery stent for treating blockages in the arteries supplying blood to the heart muscle.
- Trial name
- MEND II (NCT02189499)
- Testing
- AmM FORTITUDE Bioresorbable Drug-Eluting Coronary Scaffold
- Where
- 4 sites in Colombia
- Volunteers
- 42 people
- Sponsor
- Amaranth Medical Inc.
Acute Coronary Syndrome
Secondary Prevention in Acute Coronary Syndromes: A CALIBER Study
All contemporary guidelines for secondary prevention in acute coronary syndromes recommend a combination of aspirin, beta-blockers, ACE-inhibitors and statins. Yet underutilisation of these drugs is common.
- Trial name
- NCT01162187
- Volunteers
- 400,000 people
- Sponsor
- University College, London
Stable Angina
The PCI Choice Trial: a Pilot Randomized Trial of a Decision Aid for Patients With Stable Coronary Artery Disease
Despite several large clinical trials clearly establishing that coronary revascularization (i.e. percutaneous coronary intervention - PCI) does not prolong survival or prevent myocardial infarction (MI) for stable coronary artery…
- Trial name
- NCT01771536
- Testing
- Decision Aid
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Mayo Clinic
Neck Pain
Effectiveness of Massage of the Thoracic Region in Neck Pain
Neck pain is a common disorder in industrialized countries. Manual therapy techniques have been commonly used in the treatment of this problem.
- Trial name
- NCT06256016
- Testing
- Neck pain massage, Neck and thoracic massage
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Alcala
Coronary Artery Bypass Graft (CABG), Chest Tubes
Chest Tube-Delivered Bupivacaine to Decrease Postoperative Pain After Cardiac Surgery
Background: After heart surgery, patients require temporary chest tubes - plastic drains placed inside the chest to prevent fluid building up around the heart and lungs.
- Conditions
- Coronary Artery Bypass Graft (CABG), Chest Tubes, Post Operative Pain Control
- Trial name
- FREEZE-B (NCT07643506)
- Testing
- 0.5% Bupivacaine without epinephrine, 10cc injection of normal saline (0.9%)
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Thoracic Anesthesia, Nerve Block
The Effects of Three Different Ultrasound-guided Nerve Blocks in VATS
Ultrasound-guided mid-point transverse process to pleura block, erector spinae plane block and paravertebral block are three different methods of nerve block, used for relieving postoperative pain in thoracic anesthesia.
- Conditions
- Thoracic Anesthesia, Nerve Block, Pain, Acute
- Trial name
- NCT04829409
- Testing
- Paravertebral block, ESP block, MTP block
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Huazhong University of Science and Technology
Rib Fractures, Pain, Acute
A Retrospective Review of Rib Fracture Pain Management at a London Major Trauma Centre
Thoracic epidural analgesia (TEA) is widely considered to be the current gold standard treatment for rib fracture pain and is used in the Imperial invasive treatment pathway for rib fractures.
- Trial name
- NCT04863807
- Testing
- Regional Anaesthesia
- Where
- United Kingdom
- Volunteers
- 389 people
- Sponsor
- Imperial College Healthcare NHS Trust
Stable Angina
Stable Angina Observational Registry
The purpose of this study is to describe the clinical profile and current status of the diagnosis and management of stable angina in India by non-interventional consulting physicians (CP) through a large multicenter observational…
- Trial name
- STAR (NCT01552109)
- Where
- India
- Volunteers
- 2,079 people
- Sponsor
- Medtronic Vascular
Bladder Cancer, Postoperative Pain
Comparing Rectus Sheath Catheter to Epidural Post Cystectomy
This is a prospective randomised controlled trial that will compare the outcomes of rectus sheath catheters to epidurals in patients who have undergone a cystectomy, via a lower midline abdominal incision for bladder cancer.
- Trial name
- NCT02572804
- Testing
- Epidural, Rectus Sheath Catheters
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- Vancouver Coastal Health
Forward Head Posture, Rounded Shoulder Posture
AI Training Program vs Standard Correction for Forward Head and Rounded Shoulder in Neck Pain
this study will be to evaluate the effectiveness of AI-recommended exercise interventions versus standard corrective exercises in management of non-specific neck pain with forward head and rounded shoulder posture.
- Conditions
- Forward Head Posture, Rounded Shoulder Posture, Upper Cross Syndrome
- Trial name
- AI (NCT07236385)
- Testing
- AI based exercise, standard corrective exercises
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Cairo University
Coronary Artery Disease
Pre-hOspital Evaluation of Chest Pain Patients With sUspected Non ST-segment eLevation myocARdial Infarction Using the HEART-score With a Troponin Point-of-care Test
Overcrowding in the emergency department is an increasing problem in hospitals worldwide. Point-of-care Troponin (POC cTn) testing combined with a well investigated risk stratification tool (HEART-score) used in the ambulance may…
- Trial name
- POPular HEART (NCT04851418)
- Testing
- Possible NSTE-ACS
- Where
- 2 sites in Netherlands
- Volunteers
- 650 people
- Sponsor
- St. Antonius Hospital
In-stent Restenosis Lesion, Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))
Sirolimus With corTicOsteroid TheraPy for Rapid rEcurrences of Coronary Unexplained In-stent Restenosis
This study aims to evaluate, through a multicenter, prospective, double-blind, randomized, placebo-controlled clinical trial, whether immunosuppressive therapy improves target lesion-related cardiovascular outcomes compared to…
- Trial name
- STOP-RECUR (NCT06981845)
- Testing
- Immunosuppressive therapy
- Volunteers
- 52 people
- Sponsor
- China National Center for Cardiovascular Diseases
Sickle Cell Disease
Study to Evaluate the Effect of Ticagrelor Versus Placebo in Reducing Vaso-Occlusive Crises Rate in Pediatric Patients With Sickle Cell Disease.
The purpose of this study is to compare the effect of ticagrelor vs placebo for the reduction of Vaso-Occlusive crises in paediatric patients with Sickle Cell Disease
- Trial name
- HESTIA5 (NCT04293172)
- Testing
- Brilinta
- Sponsor
- AstraZeneca
Acute Coronary Syndrome, Percutaneous Coronary Intervention
A Cohort of Patients Undergoing Percutaneous Coronary Intervention
To investigate the risk factors involved in the occurrence and prognosis of the patients with acute coronary syndrome, patients undergoing percutaneous coronary intervention will be recruited and followed up for at least 2 years.
- Conditions
- Acute Coronary Syndrome, Percutaneous Coronary Intervention, Myocardial Infarction, Unstable Angina
- Trial name
- APCIcohort (NCT05719545)
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Su Guohai
Percutaneous Coronary Intervention (PCI), Acute Myocardial Infarction
Aerobic Exercise-induced Effect on Endothelial Function in Patients With Ischaemic Heart Disease
Endothelial dysfunction is one of the aetiological factors in ischaemic heart disease (IHD). Aerobic exercise is effective in improving endothelial function, as measured by flow-mediated dilation (FMD), in patients with IHD.
- Conditions
- Percutaneous Coronary Intervention (PCI), Acute Myocardial Infarction, Angina (Stable), Unstable Angina Pectoris
- Trial name
- ENDO-R (NCT06788275)
- Testing
- Aerobic exercise (MIT), Aerobic exercise (Short HIIT), Aerobic exercise (Long HIIT)
- Where
- 2 sites in Spain
- Volunteers
- 132 people
- Sponsor
- Instituto de Investigación Sanitaria y Biomédica de Alicante
Angina Pectoris
Women With Chest Pain and no Significant Coronary Artery Stenosis; A Study on Microvascular Resistance
Female patients presenting with persistent chest pain despite no obstructive coronary artery disease have impaired prognosis. Stress tests are often positive or inconclusive.
- Trial name
- NCT01582165
- Testing
- Rosuvastatin
- Where
- Norway
- Volunteers
- 66 people
- Sponsor
- Oslo University Hospital
Acute Coronary Syndrome
Veliflapon (DG-031)to Prevent Heart Attacks or Stroke in Patients With a History of Heart Attack or Unstable Angina
The purpose of this study is to determine if veliflapon (DG-031)can prevent a heart attack or stroke in African American patients with a history of unstable angina or myocardial infarction.
- Trial name
- NCT00353067
- Testing
- veliflapon (DG-031)
- Where
- 11 sites in United States
- Volunteers
- 3,450 people
- Sponsor
- deCODE genetics
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