Clinical trials: Chest Pains
Coronary Artery Disease, Angina Pectoris
Appropriateness of Angioplasty in Patients With Chronic Coronary Syndromes
Percutaneous coronary intervention (PCI) has dramatically changed the treatment of obstructive coronary artery disease patients.
- Trial name
- RIGHT-PCI (NCT06545448)
- Testing
- Percutaneous Coronary Intervention (PCI)
- Where
- Brazil
- Volunteers
- 1,875 people
- Sponsor
- University of Sao Paulo General Hospital
Stable Angina Pectoris, Unstable Angina Pectoris
Feasibility Study of Photopheresis Post Angioplasty
The primary objective of the study is to evaluate the difference in 6-month restenosis rates in coronary artery lesions treated by photopheresis in addition to angioplasty with stent placement, as opposed to no photopheresis…
- Conditions
- Stable Angina Pectoris, Unstable Angina Pectoris, Silent Ischemia
- Trial name
- NCT00157001
- Testing
- Photopheresis Post Angioplasty
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Atlantic Health System
Coronary Artery Disease
Clinical, Physiological and Prognostic Implication of Microvascular Status
There are several physiologic parameters in evaluating cardiovascular disease. This study will reveal which parameter is the most proper value in predicting disease severity and risk factors of patients.
- Trial name
- NCT02186093
- Where
- 5 sites in South Korea
- Volunteers
- 1,197 people
- Sponsor
- Seoul National University Hospital
Rib Fracture Multiple
Erector Spinae Plane Block vs Paravertebral Block for Pain Management in Fractured Ribs
Rib fractures pose a significant healthcare burden with its associated morbidity, long term disability, and mortality. Pulmonary morbidity is increased in these patients as a result of diminished gas exchange from fracture…
- Trial name
- NCT03883958
- Testing
- Erector Spinae Plane Block, Paravertebral Block
- Volunteers
- 60 people
- Sponsor
- Assiut University
Thoracic Discopathy, Back Pain
Physiotherapy in Thoracic Discopathy
Background and Objective: Information regarding the effects of physiotherapy on quality of life and alterations in pulmonary function tests among patients with thoracic discopathy is notably limited in the literature.
- Conditions
- Thoracic Discopathy, Back Pain, Respiratory Dysfunction
- Trial name
- NCT07749248
- Testing
- Traditional Physiotherapy, Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Angina Pectoris, Myocardial Ischemia
Self Expanding Coronary Sinus Reducer for Treatment of Symptomatic Coronary Microvascular Dysfunction (CMD)
VahatiCor's Coronary Sinus Reducer (A-FLUX) has been designed to improve angina or angina-like symptoms in patients with CMD. SERRA-I is an early feasibility study that evaluates the safety and clinical performance of the A-FLUX…
- Conditions
- Angina Pectoris, Myocardial Ischemia, Heart Diseases, Cardiovascular Diseases
- Trial name
- SERRA-I US (NCT07449325)
- Testing
- A-FLUX Reducer System
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- VahatiCor, Inc.
Coronary Arterial Disease (CAD), Angina (Stable)
The Effect of Sublingual Nitroglycerin on Absolute Coronary Blood Flow
The goal of this clinical trial is to investigate the effect of sublingual nitroglycerin on absolute coronary blood flow in adult patients undergoing coronary angiography.
- Trial name
- FLOW-NITRO (NCT06823843)
- Testing
- Glycerin trinitrate (GTN)
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- VZW Cardiovascular Research Center Aalst
Coronary Artery Disease, Percutaneous Coronary Intervention
Effect and Efficacy of Xpedition™/Alpine™, Everolimus-eluting Stent for Coronary Atherosclerosis
The objectives of this study are 1. To establish a prospective registry of the whole patients who received percutaneous coronary intervention with Xience Xpedition™/Alpine™ stent 2.
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, Acute Coronary Syndrome, Angina Pectoris
- Trial name
- HOST-ALPINE (NCT02845804)
- Testing
- Alpine
- Where
- 20 sites in South Korea
- Volunteers
- 1,533 people
- Sponsor
- Seoul National University Hospital
ACS (Acute Coronary Syndrome)
Assessing Chest Pain Using Point-of-Care High-Sensitivity Troponin I in the Emergency Department
The goal of this proposal is to improve the quality and value of care for patients with acute chest pain by investigating the potential impact of point-of-care (POC) high sensitivity cardiac troponin (hs-cTn) testing in the…
- Trial name
- ACUTE (NCT06899776)
- Testing
- Abbott i-STAT point of care (POC) device
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- Wake Forest University Health Sciences
Transcutaneous Electrical Nerve Stimulation, Procedural Pain
Effect of TENS Application After Thoracic Surgery
After thoracic surgery, a chest tube is inserted to evacuate the air and fluid formed in the pleural space and to provide hemodynamic stability.
- Trial name
- NCT05927168
- Testing
- TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University
Angina, Unstable, Cardiovascular Diseases
Postmenopausal Hormone Therapy in Unstable Angina
To determine if estrogen therapy in postmenopausal women with unstable angina reduces the incidence of ischemic episodes.
- Conditions
- Angina, Unstable, Cardiovascular Diseases, Coronary Disease, Heart Diseases
- Trial name
- NCT00000601
- Testing
- estrogen replacement therapy, estrogens, progesterone
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Parkinson Disease
Pulmonary and Musculoskeletal Impairments in Parkinson's Patients
In this study, the relationships between pain severity, chest mobility, cough strength, muscle strength, physical activity levels, and quality of life in Parkinson's disease patients will be investigated.
- Trial name
- NCT07843667
- Testing
- Physical Evaluations of Individuals with Parkinson's Disease
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Izmir Democracy University
Panic Attacks, Chest Pain
The Effects of Treatment With Sertraline for Noncardiac Chest Pain
The purpose of this study is to determine whether care as usual or intervention (consisting of sertraline versus placebo), are effective in the treatment of panic disorder and/or depression driven noncardiac chest pain.
- Conditions
- Panic Attacks, Chest Pain, Depression
- Trial name
- NCT01114100
- Testing
- sertraline
- Where
- Netherlands
- Volunteers
- 210 people
- Sponsor
- Maastricht University Medical Center
Lung Cancer, Postoperative Pain
Comparison of Robot Assisted Thoracic Surgery With Video Assisted Thoracic Surgery in Case of Lung Cancer
In this study the investigator will compare the effectiveness of robot assisted thoracic surgery (RATS) with video assisted thoracic surgery (VATS) in case of lung cancer.
- Conditions
- Lung Cancer, Postoperative Pain, Blood Loss, Inflammatory Response
- Trial name
- NCT03152071
- Testing
- Robot assited thoracic surgery, Video assited thoracic surgery
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitair Ziekenhuis Brussel
Pain, Acute, Pain, Chest
Transversus Thoracic Muscle Plane Block for Open Heart Surgery
Poststernotomy pain is a complication of cardiac surgery. Poorly controlled pain is associated with myocardial ischemia, cardiac arrhythmias, hypercoagulability, pulmonary complications, and increased rates of delirium and wound…
- Trial name
- TTMP (NCT04094532)
- Testing
- Bupivacaine, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ataturk University
Angina Pectoris
Vescell(TM) for the Treatment of Patients With Severe Anginal Syndrome With or Without Heart Failure
Evaluation of an intracoronary injection of ex-vivo generated autologous Angiogenic Cells Precursors (ACPs) to treat patients suffering from severe angina not responsive to maximal drug treatment or not willing or without option…
- Trial name
- NCT00416663
- Testing
- Intracoronary administration of autologous ACPs
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- TheraVitae Ltd.
Coronary Artery Disease, Stable Angina
The Effect Of Ticagrelor On Saphenous Vein Graft Patency In Patients Undergoing Coronary Artery Bypass Grafting Surgery
In the POPular CABG study we investigate if the addition of ticagrelor, a drug that inhibits blood platelets from clotting, to treatment with aspirin will reduce the rate of saphenous vein graft occlusion as assessed with…
- Conditions
- Coronary Artery Disease, Stable Angina, Acute Coronary Syndrome
- Trial name
- POPular CABG (NCT02352402)
- Testing
- Ticagrelor
- Where
- 6 sites in Netherlands
- Volunteers
- 487 people
- Sponsor
- J.M. ten Berg
Hypertension, Chronic Stable Angina
Bioequivalency Study of Amlodipine Tablets Under Fed Conditions
The objective of this study was the bioequivalence of a Roxane Laboratories' Amlodipine Besylate tablets, 10 mg, to Norvasc® Tablets, 10 mg (Pfizer) under fed conditions using a single-dose, randomized, 2-treatment, 2-period…
- Conditions
- Hypertension, Chronic Stable Angina, Vasospastic Angina
- Trial name
- NCT00601302
- Testing
- Amlodipine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Acute Myocardial Ischemia
Non Invasive dP/dt to Detect an Acute Ischemic Myocardial Dysfunction in Emergency Department
Most patients presenting to the emergency department with chest discomfort have a nonischemic ECG and biomarkers of myocardial necrosis within normal limits.
- Trial name
- dP/dtAMDED (NCT02138604)
- Where
- Tunisia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Chest Pain, Acute Coronary Syndrome, Myocardial Infarction
Magnetocardiography in the Accurate Identification of Severe Coronary Lesions and Myocardial Necrosis
Magnetocardiography (MCG) is a promising noninvasive and accurate method for detecting myocardial ischemia. Although progress has been made in this area, there is a lack of studies using up-to-date examination instruments for the…
- Trial name
- NCT05392712
- Testing
- Magnetometer
- Where
- China
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
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