Clinical trials: Chest Pains
Acute Myocardial Infarction (AMI), Percutaneous Coronary Intervention (PCI)
BRIDGE Trial: Embedding Consumer-grade mHealth Technologies Into Cardiac Rehabilitation
The purpose of the BRIDGE study is to learn whether supplementing traditional center-based cardiac rehabilitation (CBCR) with a mobile health technology intervention can help patients monitor their health, stay engaged in healthy…
- Conditions
- Acute Myocardial Infarction (AMI), Percutaneous Coronary Intervention (PCI), Coronary Artery Bypass Graft Surgery (CABG), Chronic Heart Failure With Reduced Ejection Fraction (HFrEF)
- Trial name
- BRIDGE (NCT07741396)
- Testing
- CBCR, BRIDGE mHealth intervention
- Volunteers
- 30 people
- Sponsor
- University of Illinois Chicago
Postoperative Pain
Quality of Postoperative Pain Management Following Thoracic Surgery
The purpose of this study is to assess the quality of postoperative pain management in a Canadian teaching hospital following thoracic surgery.
- Trial name
- NCT01616550
- Testing
- Assessment of pain using the Brief Pain Questionnaire, Assessment of pain relief using a Verbal Numeric Scale (VNS), Assessment of patient' satisfaction with pain relief
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Epipericardial Fat Necrosis
Epipericardial Fat Necrosis: A Misdiagnosed Condition
Epipericardial fat necrosis is a benign and self-limited condition that mainly curses with acute pleuritic chest pain and therefore must be an important differential diagnosis for patients in emergency department (ED).
- Trial name
- epipericardial (NCT01903980)
- Testing
- No intervention. It is a retrospective study
- Where
- 2 sites in Brazil
- Volunteers
- 10 people
- Sponsor
- Hospital Sirio-Libanes
Acute Myocardial Infarction, Pulmonary Embolism
Retrospective Study of Acute Chest Pain in Extremely Critical Condition for More Than Ten Years
Acute non-traumatic chest pain is a common kind of symptom in extremely critical condition, with various pathogenesis and different level of risk . Chest pain in high risk takes 1/3 of that.
- Conditions
- Acute Myocardial Infarction, Pulmonary Embolism, Aortic Dissection
- Trial name
- RESPECT (NCT02837120)
- Where
- China
- Volunteers
- 7,000 people
- Sponsor
- Qilu Hospital of Shandong University
Peri-procedural Myocardial Infarction, Heart Failure Hospitalization
Clinical Evidence With Biomarker Confirmation for PPMI in PCI Clinical Trials Study
The goal of this prospective, multicenter, non-randomized observational study is to better identify and understand periprocedural myocardial injury among adults undergoing percutaneous coronary intervention (PCI) for stable…
- Conditions
- Peri-procedural Myocardial Infarction, Heart Failure Hospitalization, Mortality, Stable Angina Pectoris
- Trial name
- CEC-PPMI (NCT07848529)
- Testing
- Biomarker testing
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Baim Institute for Clinical Research
Stable Angina, Unstable Angina
Drug Coated Balloon Compared to Bare Metal Stent for de Novo Coronary Artery Lesions
This randomized trial will assess the efficacy of Drug Coated Balloon (DCB) compared to Bare Metal Stent (BMS) using Fractional Flow Reserve (FFR) guidance for de novo coronary artery lesions in patients unable to tolerate dual…
- Trial name
- NCT02456402
- Testing
- Drug Coated Balloon, Bare Metal Stent
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Ulsan University Hospital
Back Pain
Evaluation of How Different Dosages of Spinal Manipulation Modulate Spinal Stiffness in Participants With Back Pain
This study evaluate the relationships between spinal manipulative therapy dosage (speed and peak force), the resulting modulation of thoracic spinal stiffness and changes in the clinical status in participants with chronic…
- Trial name
- NCT03063177
- Testing
- Spinal manipulative therapy
- Where
- Canada
- Volunteers
- 81 people
- Sponsor
- Université du Québec à Trois-Rivières
Refractory Angina, Raised Lipoprotein(a)>50mg/dL or >500mg/L
Lipoprotein Apheresis in Refractory Angina Study
The goal of this study is to determine the impact of apheresis on clinical parameters and symptoms of patients with refractory angina and raised Lp(a).
- Trial name
- NCT01796912
- Testing
- Lipoprotein Apheresis
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Imperial College London
Angina, Non-obstructive Coronary Artery Disease
Imaging Coronary Microvascular Dysfunction (CMD) Study
Angina is a common clinical symptom of ischemic heart disease, affecting up to 11 million people in the United States alone, and 112 million people globally.
- Trial name
- NCT05634031
- Testing
- PET imaging, Coronary CT angiogram, Functional Angiography
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Postoperative Pain
NSAIDs With Morphine-PCA Compared to Epidural Analgesia in Thoracotomy Pain
The investigators investigated whether a strictly controlled pain management with patients participating in a clinical study can attenuate persistence of post-thoracotomy pain.
- Trial name
- NCT01541137
- Testing
- Diclofenac, parecoxib/ valdecoxib, patient controlled epidural analgesia
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Helsinki University Central Hospital
Coronary Artery Disease
Influence of Lipid Lowering on Impaired Coronary Flow
This study assess in patients with stable chest pain and coronary artery disease (CAD) determined by coronary CTA whether cholesterol lowering with regression of coronary adverse plaque characteristics is associated with recovery…
- Trial name
- NCT05368545
- Testing
- High intensity lipid lowering
- Where
- Denmark
- Volunteers
- 109 people
- Sponsor
- Aarhus University Hospital
Pain, Postoperative
Naproxen for Acute Pain After Surgery: A Randomized, Placebo-Controlled Trial
The purpose of this study is to determine whether using an additional 48 hours of oral naproxen, after other post-operative pain medications have been stopped, will be effective in reducing opiate pain medication requirements and…
- Trial name
- NAPS (NCT00615875)
- Testing
- naproxen
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Hamilton Health Sciences Corporation
Chest Pain, Acute Coronary Syndrome
AI-Assisted Interpretation of Cardiac CT in the Emergency Department
" This prospective, pragmatic, randomized controlled trial is designed to evaluate the impact of an artificial intelligence (AI)-based coronary computed tomography angiography (CCTA) interpretation tool (Angiomics) on emergency…
- Conditions
- Chest Pain, Acute Coronary Syndrome, Coronary Artery Disease
- Trial name
- NCT07235657
- Testing
- Angiomics AI-based Coronary CT Interpretation Tool, Standard CCTA Interpretation without AI
- Where
- South Korea
- Volunteers
- 530 people
- Sponsor
- Yonsei University
Acute Coronary Syndrome
Diagnostic Performance of Coronary Calcification Detection on CT Scan
thoracic pain is one of the most frequent reasons for consulting the emergency room. Chest pain can be a sign of different pathologies with a wide range of severity, from life-threatening aortic dissection or myocardial…
- Trial name
- Calci-DT (NCT05538117)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Chest Pain, Coronary Artery Disease
Risk Markers in the Acute Coronary Syndromes
The main aim of this trial is to assess the long-term prognostic value of different types of Factor XIIa in an unselected, single center series of 871 chest pain patients admitted to the emergency unit, employing blood samples…
- Conditions
- Chest Pain, Coronary Artery Disease, Unstable Angina Pectoris, Myocardial Infarction
- Trial name
- RACS (NCT00521976)
- Where
- Norway
- Volunteers
- 871 people
- Sponsor
- Helse Stavanger HF
Thoracic Surgery
Comparison of Bupivacaine Liposomal vs Bupivacaine Combined With Dexamethasone for Postoperative Pain in VATS
The purpose of this study, is to investigate the effectiveness of ultrasound-guided rhombic intercostal nerve block for postoperative pain control in thoracoscopic pulmonary resection with bupivacaine liposomes versus bupivacaine…
- Trial name
- NCT06392191
- Testing
- Rhombic intercostal nerve block(Received liposomal bupivacaine 93 mg and bupivacaine 25 mg diluted to 20 ml), Rhombic intercostal nerve block(Receive standard bupivacaine 105 mg diluted to 20 ml with dexamethasone 5 mg.)
- Where
- China
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Jiaxing University
Coronary Artery Disease
An Epidemiological Cohort Study of Acute Coronary Syndromes in The Greek Population. The PHAETHON Study
A nationwide registry of patients with acute coronary disease to evaluate epidemiological patient characteristics, medical management, implementation of invasive strategy, patient outcome and impact on quality of life in Greece.
- Trial name
- PHAETHON (NCT02420808)
- Where
- Greece
- Volunteers
- 800 people
- Sponsor
- Hellenic Cardiovascular Research Society
Pain, Acute, Erector Spinae Plane Block
Effect of Ultrasound Guided Thoracic Interfascial Plane Block Versus Erector Spinae Plane Block After Mastectomy
This study will be conducted to compare the efficacy of ultrasound guided thoracic interfascial plane block versus ultrasound guided erector spinae plane block on acute and chronic pain after modified radical mastectomy surgery.
- Conditions
- Pain, Acute, Erector Spinae Plane Block, Mastectomy, Modified Radical, Thoracic Interfascial Plane Block
- Trial name
- NCT05176938
- Testing
- Ultrasound guided Thoracic Interfascial plane Block (TIFB), Ultrasound guided Erector Spinae plane Block (ESPB)
- Volunteers
- 90 people
- Sponsor
- Tanta University
Acute Coronary Syndrome, Myocardial Infarction (MI)
Clinical Echocardiography and S' Wave for Early Recognition of Acute Coronary Syndrome in the Emergency Department, A Prospective Study
The goal of this prospective observational study is to assess the diagnostic accuracy of the tissue Doppler imaging (TDI) S' wave in detecting acute coronary syndrome (ACS) in adult patients presenting to the emergency department…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction (MI), Non-ST Elevation Myocardial Infarction, Unstable Angina
- Trial name
- CLEAR_ECHO (NCT06860997)
- Testing
- Tissue Doppler Imaging (TDI) S' Wave Echocardiography
- Where
- Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Chest Pain, Angina
Stress Echocardiography and Heart Computed Tomography (CT) Scan in Emergency Department Patients With Chest Pain
The purpose of this study is to determine whether stress echocardiography or computed tomography (CT) of the heart is better at diagnosing emergency room chest pain patients to select appropriate candidates for hospitalization…
- Conditions
- Chest Pain, Angina, Angina Pectoris, Coronary Artery Disease
- Trial name
- NCT01384448
- Testing
- Stress Echocardiography, Coronary CT Angiography
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Montefiore Medical Center
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