Clinical trials: Chest Pains
STEMI - ST-segment Elevation Myocardial Infarction, Chest Pain
SMARTwatch for the Diagnosis of ST-segment Elevation Myocardial Infarction in Patients With Chest Pain
The main symptom that initiates the diagnostic and therapeutic process for patients with suspected acute coronary syndrome is chest pain.
- Trial name
- SMART-CART-AMI (NCT07780942)
- Testing
- ECG smartwatch recording
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital General Universitario Santa Lucia
Myocardial Infarction, Stable Angina
Readiness for Behavior Change After a Heart Attack
The purpose of this study is to test if an early appointment (within 10 days) when compared to a standard appointment (5 weeks) will affect attendance at the Cardiac Rehabilitation orientation and subsequent enrollment into…
- Conditions
- Myocardial Infarction, Stable Angina, Coronary Artery Disease
- Trial name
- ENROLL (NCT01596036)
- Testing
- Early appointment (within 10 days), Routine referral (at 5 weeks)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Henry Ford Health System
Postoperative Pain, Lung Cancer
Postoperative Pain Management on Patients Undergoing Lung Tumor Resection
Multimodal analgesia (MMA) is an essential part of Enhanced Recovery After Surgery (ERAS) protocol. The principle of MMA is to manage pain with analgesics of multiple classes acting on distinct target sites through different…
- Conditions
- Postoperative Pain, Lung Cancer, Lung Tumor
- Trial name
- NCT06397807
- Testing
- Dinalbuphine sebacate, Analgesic injectables, Enteral analgesics
- Volunteers
- 400 people
- Sponsor
- China Medical University Hospital
Coronary Heart Disease, Unstable Angina
Fecal Microbiota and Monocyte Trained Immunity in CHD Patients With Different hsCRP
This single-center study enrolled patients aged 35-75 years who were diagnosed with unstable angina (UA), and had at least one of the three major coronary arteries with a ≥ 50% reduction in lumen diameter by angiographic visual…
- Trial name
- NCT06562309
- Testing
- take feces and blood samples from patients
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Subacromial Impingement Syndrome, Exercise Addiction
Effects of Exercise or Taping on Pain, Function, Range of Motion, Strength and Kyphosis in Subacromial Pain Syndrome
Participants with subacromial pain syndrome underwent shoulder exercises. In addition to the exercises, group A received thoracic extension exercise and group B received kinesio taping.
- Conditions
- Subacromial Impingement Syndrome, Exercise Addiction, Shoulder Pain
- Trial name
- NCT06777121
- Testing
- Shoulder exercises + Thoracic extension exercise, Shoulder exercises + Thoracic kinesio taping, Shoulder exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sevtap Günay
Unstable Angina
MMP Polymorphisms and Acute Coronary Syndromes
Some Matrix Metalloproteases, proteases degrading the extracellular matrix, play a relevant role in structure and stability of atherosclerotic plaques.
- Trial name
- NCT00484406
- Where
- 2 sites in Italy
- Sponsor
- University of Trieste
Local Anesthetic Systemic Toxicity, Pain
Ropivacaine Pharmacokinetics in ESP Blocks
This is a pharmacokinetic study to determine risk of local anesthetic systemic toxicity of ropivacaine when used in erector spinae plane blocks for thoracic surgery.
- Conditions
- Local Anesthetic Systemic Toxicity, Pain, Quality of Recovery
- Trial name
- NCT04807504
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Thomas Jefferson University
Coronary Atherosclerosis
Endothelial Function-guided Therapy Compared to Usual Care in Patients With NOCAD
The current study is designed to test the hypothesis that compared to conventional treatment; endothelial function-guided treatment reduces adverse cardiovascular events in patients with non-obstructive coronary artery disease…
- Trial name
- EndoGET (NCT02313987)
- Where
- 2 sites in Israel
- Sponsor
- Itamar-Medical, Israel
Coronary Artery Disease, Unstable Angina
Restore EF Observational Study
A multi-center, prospective, observational, non-interventional single arm, study of the intermediate-term clinical outcomes collected from electronic health records of high-risk patients which have previously undergone standard…
- Conditions
- Coronary Artery Disease, Unstable Angina, Angina, Stable, NSTEMI - Non-ST Segment Elevation MI
- Trial name
- NCT04648306
- Testing
- Prophylactic Impella support for a non-emergent PCI
- Where
- 21 sites in United States
- Volunteers
- 406 people
- Sponsor
- Abiomed Inc.
Unstable Angina
Incidence, Clinical Characteristics and Outcomes of Unstable Angina in the contempoRary Area.
The study aims to evaluate clinical characteristics and prognostic of a contemporary population of patients with UA defined using T hs-cTn measurements The study includes all patients admitted in 2 French university centers with…
- Trial name
- ICAR (NCT06378333)
- Testing
- patients who underwent coronary angiography
- Where
- France
- Volunteers
- 210 people
- Sponsor
- University Hospital, Montpellier
Noncardiac Chest Pain, Panic Attack
Validation of the Panic Screening Score in Patient With Unexplained Chest Pain
Panic-like anxiety ( panic attacks with or without panic disorder), a highly treatable condition, is the most prevalent condition associated with unexplained chest pain in the emergency department.
- Trial name
- NCT02405052
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 3,000 people
- Sponsor
- CISSS de Chaudière-Appalaches
Coronary Artery Calcification, Ischemic Heart Disease
The Influence of Modifying Highly Calcified Coronary Lesions on Coronary Microcirculation
This is a prospective, single-center, three-arm study to evaluate the impact of severely calcified coronary lesions treatment on microvascular circulation.
- Conditions
- Coronary Artery Calcification, Ischemic Heart Disease, Non-ST-Segment Elevation Myocardial Infarction (NSTEMI), Coronary Artery Disease
- Trial name
- NCT06507449
- Testing
- Lithotripsy, Orbital atherectomy, High-pressure non-compliant balloon
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Silesia
Neuropathic Pain, Chronic Pain
Post-operative Thoracic Epidural Analgesia and Incidence of Major Complications: a Large Retrospective Dual Center Experi-ence
A retrospective observational dual center study investigating side effects and major complications after thoracic epidural insertion according to local safety protocols.
- Conditions
- Neuropathic Pain, Chronic Pain, Thoracic Cancer
- Trial name
- NCT05909007
- Testing
- thoracic epidural insertion
- Where
- Greece
- Volunteers
- 1,145 people, healthy volunteers welcome
- Sponsor
- AHEPA University Hospital
Stable Angina, Metabolic Syndrome
Impact of Ranolazine in Blood Markers in Women With Angina and Metabolic Syndrome
The purpose of this study is to determine the effects of ranolazine on different markers of cardiometabolic disease in women with stable angina.
- Trial name
- IRMA (NCT02252406)
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Florida
Coronary Artery Disease
High Clopidogrel Dose Versus Prasugrel and Ticagrelor in High Reactive Stable Patients
Dual antiplatelet therapy with Aspirin and Clopidogrel for at least one year is essential in patients following an acute coronary syndrome (ACS) or percutaneous coronary intervention (PCI) with drug eluting stent(s) implantation.
- Trial name
- TRIPLETE RESET (NCT01543932)
- Testing
- Clopidogrel, Prasugrel, Ticagrelor
- Where
- Italy
- Volunteers
- 81 people
- Sponsor
- University of Roma La Sapienza
Coronary Artery Disease, Coronary Microvascular Dysfunction
The Effects of Tirzepatide in People With Overweight/Obesity and Coronary Artery Disease
The objective of this study is to investigate, as a proof-of-principle, long-term (52 weeks) effects of tirzepatide once-weekly vs.
- Conditions
- Coronary Artery Disease, Coronary Microvascular Dysfunction, Overweight or Obesity, Stable Angina Pectoris
- Trial name
- IDEAL-COR (NCT06606821)
- Testing
- Tirzepatide
- Where
- 3 sites in Denmark
- Volunteers
- 124 people
- Sponsor
- Tina Vilsbøll
Stable Angina, Coronary Artery Disease
CCTA, CACS and ECG Stress Testing in Patients With Suspected CAD: Precision Phenotyping and Financial Evaluation
The "DATASET-PRECISE", a 3-arm parallel randomized study, aims to provide new insights in risk stratification of patients with suspected CAD in the Greek population.
- Conditions
- Stable Angina, Coronary Artery Disease, Atherosclerosis, Coronary Artery Calcification
- Trial name
- DATASET (NCT04424121)
- Testing
- CCTA
- Where
- 3 sites in Greece
- Volunteers
- 900 people
- Sponsor
- Aristotle University Of Thessaloniki
Fatal Outcome
Proadrenomedullin for Early Risk Assessment in the Emergency Department
The study ia aiming to the assessment of Mid-Regional proadrenomedullin (MR-proADM) as a novel biomarker that can provide accurate short-, mid- and long term prognostic information in the triage and multi-dimensional risk…
- Trial name
- ADRISK (NCT02823704)
- Where
- Greece
- Volunteers
- 300 people
- Sponsor
- University of Athens
Postoperative Pain
Continuous Ultrasound Guided Erector Spinae Plane Block vs Thoracic Paravertebral Block
in this study the investigators will investigate and compare the analgesic efficacy of two techniques (continuous TPVB and continuous ESPB) in relieving thoracotomy pain
- Trial name
- NCT05898607
- Testing
- continuous Thoracic paravertebral block, continuous Erector spinae plane block
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Amal Gouda Elsayed Safan
Cardiovascular Disease, Stable Angina
Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Stable Angina, NSTEMI and STEMI Undergoing PCI
Ticagrelor therapy has been shown to reduce the rates of cardiovascular events and all-cause mortality compared to clopidogrel therapy in patients with acute coronary syndromes (ACS).
- Conditions
- Cardiovascular Disease, Stable Angina, Myocardial Infarction, Coronary Artery Disease
- Trial name
- NCT02012140
- Testing
- ticagrelor
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- LifeBridge Health
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