Clinical trials: Chest Pains
Thoracic
Effects of Thoracic Erector Spinae Plane Blockade on Acute and Chronic Pain After Video Assisted Thoracoscopic Surgery (VATS)
This is a prospective randomized study intended to assess the efficacy of erector spinae plane analgesia on acute and chronic postoperative pain for VATS procedures.
- Trial name
- NCT04208542
- Testing
- ESP block
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Yonsei University
Pain, Postoperative
Thoracic Paravertebral Blockade in Video Assisted Thoracoscopic Surgery (VATS)
Video-assisted thoracoscopic surgeries (VATS) include severe postoperative acute pain which is also a predictor of chronic pain.
- Trial name
- VATS (NCT02302586)
- Testing
- Thoracic paravertebral block (TPVB), Patient Controlled Analgesia (IV PCA)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Open-Heart Surgery
Effect of Box Breathing Before Chest Tube Removal After Open-Heart Surgery
This randomized controlled trial aims to evaluate the effects of box breathing performed before chest tube removal on pain, anxiety, dyspnea, and hemodynamic parameters in patients undergoing open-heart surgery.
- Trial name
- NCT07808658
- Testing
- Box breathing
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Mersin University
Chest Pain, Major Adverse Cardiovascular Events
Prognostic Value of Non-invasive Index of Endothelial Function.
The objective of this study is to determine the prognostic performance of endothelial function assessment, using endothelial peripheral arterial tonometry (Endo-PAT), associated to TIMI risk score, in patients consulting the…
- Trial name
- NCT03164226
- Testing
- Digital plethysmography in stratifying the cardiovascular risk for patients consulting for chest pain
- Where
- Tunisia
- Volunteers
- 503 people
- Sponsor
- University of Monastir
Microvascular Angina
Study to Evaluate Effect of Nebivolol on Angina in Women With Microvascular Disease
Women have less significant blockages of coronary arteries, however have greater symptoms and worse outcomes compared to their age-matched male counterparts.
- Trial name
- NIRVANA (NCT01665508)
- Testing
- Nebivolol
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Massachusetts General Hospital
Acute Coronary Syndrome, Non-ST Elevation (NSTEMI) Myocardial Infarction
An Efficacy and Outcome Study of Supplemental Oxygen Treatment in Patients With Suspected Myocardial Infarction
The use of supplemental oxygen in the setting of suspected acute myocardial infarction (AMI) is manifested in international treatment guidelines and established in prehospital and hospital clinical routine throughout the world.
- Conditions
- Acute Coronary Syndrome, Non-ST Elevation (NSTEMI) Myocardial Infarction, Acute ST Segment Elevation Myocardial Infarction, Angina, Unstable
- Trial name
- DETO2X-AMI (NCT01787110)
- Testing
- Oxygen
- Where
- 34 sites in Sweden
- Volunteers
- 6,629 people
- Sponsor
- Karolinska Institutet
Neck Pain
A Comparison of Two Thoracic Manipulation Techniques to Improve Neck Pain
The purpose of this study is to compare the short-term effects of two different thoracic spine thrust manipulation techniques on neck range-of-motion, pain, and self-reported disability in individuals experiencing neck pain.
- Trial name
- NCT02972710
- Testing
- Supine thoracic spine thrust manipulation, Seated thoracic spine thrust manipulation
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Northern Arizona University
Chest Pain, Shortness of Breath
ProspEctive First Evaluation in Chest Pain Trial
The purpose of this study is to determine the best initial test in patients admitted to the hospital complaining of chest pain.
- Conditions
- Chest Pain, Shortness of Breath, Suspected Acute Coronary Syndrome
- Trial name
- PERFECT (NCT01604655)
- Testing
- Coronary CT Angiography, Stress Test
- Where
- United States
- Volunteers
- 411 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Coronary Artery Disease (CAD)
Improved Management of Patients With Recent-Onset Stable Chest Pain
In Germany, coronary CT offers an accurate and less burdensome alternative to cardiac catheterisation for evaluating suspected coronary artery disease, but it is still underused.
- Trial name
- IMPRO (NCT07476040)
- Testing
- IMPRO - Cross-Sectoral Care Model for Coronary Diagnostics
- Where
- 39 sites in Germany
- Volunteers
- 3,369 people
- Sponsor
- Philipps University Marburg
Coronary Heart Disease
Efficacy of Dun Ye Guan Xin Ning Tablet in Patients With Stable Angina Pectoris
This registry is designed to investigate factors affecting the efficacy of Dun Ye Guan Xin Ning tablet on patients with stable angina.
- Trial name
- NCT03198091
- Testing
- Dun Ye Guan Xin Ning
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Peking University First Hospital
Chest Pain
Vericiguat in Patients With Coronary Microvascular Dysfunction Causing Stable Chest Pain (V-COM)
This is a randomised controlled trial to determine the effectiveness of Vericiguat to improve stress myocardial blood flow (MBF) and myocardial perfusion reserve as measured by cardiac magnetic resonance (CMR) imaging.
- Trial name
- NCT06239974
- Testing
- Vericiguat, Stress Cardiac Magnetic Resonance
- Where
- Hong Kong
- Volunteers
- 94 people
- Sponsor
- The University of Hong Kong
Chest Tube Removal, Heart; Surgery, Heart, Functional Disturbance as Result
Foot Reflexology to Reduce Pain and Anxiety Before Chest Tube Removal
In open heart surgeries, patients experience severe pain due to tissue trauma, damage to intercostal nerves, and muscle spasm due to pulling tubes from the mediastinal space and between the pleural leaves pull during chet tube…
- Conditions
- Chest Tube Removal, Heart; Surgery, Heart, Functional Disturbance as Result, Pain, Anxiety
- Trial name
- NCT05032469
- Testing
- Reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Baskent University
Lung Cancer, Tuberculosis
A Trial on Clinical Efficacy of 1% Versus 2% Lignocaine in Cough Suppression and Pain Relief in Patients Undergoing Flexible Bronchoscopy
Flexible bronchoscopy is a common procedure performed by pulmonary physicians. The use of topical anesthesia, analgesia, and sedation during flexible bronchoscopy varies among physicians, institutions and geographic locations…
- Conditions
- Lung Cancer, Tuberculosis, Sarcoidosis, Interstitial Lung Disease
- Trial name
- NCT01955824
- Testing
- 1% lignocaine, 2% lignocaine
- Where
- India
- Volunteers
- 500 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Lung Cancer
Postoperative Pain After Single Port, Two Ports and Three Ports VATS Lobectomy
This single-center, prospective, randomized controlled trial was designed to assess and compare the postoperative pain after VATS lobectomy performed though one, two and three incisions.
- Trial name
- NCT03228056
- Testing
- pain intensity measured in VAS scale
- Where
- 2 sites in Poland
- Volunteers
- 90 people
- Sponsor
- Pulmonary Hospital Zakopane
Coronary Artery Disease, Angina Pectoris
Understanding Clinician Utilization of Corus CAD (Age/Sex/Gene Expression Score - ASGES) in Clinical Decision Making
The purpose of this study is to understand the use of Corus CAD also known as Age/Sex/Gene Expression score (ASGES) in the clinical decision making process of patients who underwent the evaluation of chest pain or anginal…
- Conditions
- Coronary Artery Disease, Angina Pectoris, Chest Pain, Cardiovascular Diseases
- Trial name
- UCU-CARD (NCT02223286)
- Testing
- Corus CAD
- Where
- 3 sites in United States
- Volunteers
- 552 people
- Sponsor
- CardioDx
Chronic Postoperative Pain, Chest Pain
The Effectiveness of Thoracal Epidural Steroid and Local Anesthetic Injection
The primary objective was to evaluate the effectiveness of thoracic interlaminar epidural injections in alleviating pain and enhancing function in patients suffering from chronic mid and/or upper back pain.
- Conditions
- Chronic Postoperative Pain, Chest Pain, Back Pain
- Trial name
- NCT06507995
- Testing
- thoracic interlaminar epidural injection
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara University
Stable Angina, Unstable Angina
COMBO-Stent in Patients on Chronic Anticoagulant Therapy (COSTA) COSTA-Bleed and COSTA-Outcome Trials
Prospective, multi-centre, randomized, open-label, parallel comparisons to evaluate the incidence of bleedings (COSTA-Bleed) and the incidence of ischemic and bleeding events (COSTA-Outcome) following a therapy with the abluminal…
- Conditions
- Stable Angina, Unstable Angina, STEMI, NSTEMI
- Trial name
- COSTA (NCT02723981)
- Testing
- COMBO-Stent, Clopidogrel, Vitamin K Antagonist, Rivaroxaban, Dabigatran, Any drug eluting stent oder bare metal sent
- Where
- 10 sites in Germany
- Sponsor
- IHF GmbH - Institut für Herzinfarktforschung
Chest Pain, Acute Coronary Syndrome
Computed Tomography Coronary Angiogram (CTCA) Versus Traditional Care in Emergency Department Assessment of Potential Acute Coronary Syndromes (ACS)
This multi-center, randomized, controlled trial conducted in Emergency Departments (ED) compares computed tomography (CT) coronary angiography with the traditional approach (usual care) for low- to intermediate-risk chest pain…
- Conditions
- Chest Pain, Acute Coronary Syndrome, Acute Myocardial Infarction, Coronary Artery Disease
- Trial name
- NCT00933400
- Testing
- CT Coronary Angiography (CTCA), Traditional Strategy
- Where
- 5 sites in United States
- Volunteers
- 1,392 people
- Sponsor
- American College of Radiology
Postmenopausal Women, Stable Angina Pectoris
Coronary Artery Disease (CAD) in Postmenopausal Women
Aim of this study is the determination of a valid procedure for ischemia diagnositc in postmenopausal women.
- Trial name
- FEMCAD (NCT00763464)
- Testing
- stress-echocardiography, stress-MRI
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Coronary Artery Disease, Atherosclerosis, Coronary
HIV Infection And Evolvement of Atherosclerotic Plaque
In a prospective multi-center observational study, 200 HIV-infected patients treated with antiretroviral treatment (ART) and who suffered from coronary artery disease (CAD) will be enrolled.
- Conditions
- Coronary Artery Disease, Atherosclerosis, Coronary, Hiv, HIV Infections
- Trial name
- HIVE (NCT04810364)
- Testing
- Quantitative coronary angiography, intravascular imaging with percutaneous intervention
- Where
- 2 sites in Russia
- Volunteers
- 1,000 people
- Sponsor
- Central Clinical Hospital of the Russian Academy of Sciences
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