Clinical trials: Chest Wall Disease
COPD Exacerbation Acute
The Effect of Airway and Chest Wall Oscillation on Respiratory Functions in COPD Patients in Acute Exacerbation
Chronic obstructive pulmonary disease (COPD); It is a common, treatable and preventable disease characterized by progressive and irreversible airflow limitation and has systemic effects with respiratory system involvement.
- Trial name
- NCT06274957
- Testing
- CONTROL, PEP DEVICE, HFCWO DEVICE
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Saglik Bilimleri Universitesi
Pectus Excavatum, Pectus Carinatum
Chest Wall Deformities Beyond the Chest Wall
Pectus excavatum (PE) and pectus carinatum (PC) are chest wall deformities that may influence respiratory function, physical capacity, posture, and quality of life.
- Trial name
- BEYOND (NCT07844382)
- Where
- Turkey (Türkiye)
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Cystic Fibrosis
Effects of High-Frequency Chest Wall Oscillation Combined With Concurrent Training on Cough,in Cystic Fibrosis Patients
This randomized clinical trial aims to evaluate the effects of high-frequency chest wall oscillation (HFCWO) combined with concurrent training on cough, sputum clearance, exercise tolerance, and respiratory muscle strength in…
- Trial name
- NCT07519460
- Testing
- High-Frequency Chest Wall Oscillation, Concurrent Training
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Restrictive Lung Disease
Relation Between Pulmonary Function Tests and Ultrasonographic Chest Joints
Ultrasonography can detect different changes in anterior chest wall (ACW) joints in patients with Rheumatoid arthritis (RA) even before being clinically manifested.
- Trial name
- Ultrasound (NCT05119491)
- Testing
- uitrasonography and spirometry
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Zagazig University
Chronic Obstructive Pulmonary Disease
High Frequency Chest Wall Oscillation in Chronic Obstructive Pulmonary Disease (COPD)
Patients with Chronic obstructive pulmonary disease (COPD) tend to have cough, excess mucus production and breathlessness as cardinal features.
- Trial name
- NCT00863616
- Testing
- HFCWO - SmartVest
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- East and North Hertfordshire NHS Trust
Respiratory Failure, Neuromuscular Disease
Autotitrating Versus Standard Non-invasive Ventilation (NIV) in Acute Exacerbation of Respiratory Failure
The aim of the study is to compare the efficacy and tolerance of autotitrating non-invasive ventilation (NIV) versus standard NIV in patients admitted to hospital with acute exacerbation of chronic respiratory failure.
- Conditions
- Respiratory Failure, Neuromuscular Disease, Chest Wall Disorder, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT01174316
- Testing
- AutoVPAP™, VPAPIIIST-A™
- Where
- United Kingdom
- Sponsor
- ResMed
Cystic Fibrosis
Long-term Study, Comparing Vest Therapy to Positive Expiratory Pressure (PEP) Therapy in the Treatment of Cystic Fibrosis
This study is a preliminary study designed to determine the safety and effectiveness of HFCWO using the InCourage vest system as an airway clearance technique for the treatment of CF.
- Trial name
- NCT00817180
- Testing
- Positive Expiratory Pressure (PEP), High Frequency Chest Wall Oscillation (HFCWO) using InCourage Vest System
- Where
- 13 sites in Canada
- Volunteers
- 107 people
- Sponsor
- University of British Columbia
Breast Cancer
Comparing 3-D Printed vs Standard Bolus for Breast Cancer Chest Wall Radiotherapy
This is a cohort study of 16 women undergoing post-mastectomy chest wall radiotherapy for breast cancer comparing two ways of modifying the radiation beam with bolus (a 5mm rubber substance placed on the skin to modify the…
- Trial name
- NCT02544945
- Testing
- 3D printed bolus, Standard bolus
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Rob Rutledge
Thoracic Diseases
Effect of Manual Chest Wall Vibration on Respiratory Function and Chest Tube Duration After Thoracic Surgery
This study was conducted to determine the effects of a manual vibration technique applied to the chest wall on the duration of chest tube placement, secretion clearance, and hemodynamic parameters in patients with chest tubes.
- Trial name
- NCT07549555
- Testing
- Chest Wall Oscillation, Conventional Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Saglik Bilimleri Universitesi
COPD (With - Without Rehabilitation)
Effects of Structural Integration on Chest Wall Expansion Among COPD Patients
The present study aims to investigate the effects of the 10-Series of Structural Integration on chest wall expansion in patients with stable COPD using a randomized controlled trial design.
- Trial name
- NCT07752420
- Testing
- Structural Integration with Conventional Pulmonary Rehabilitation, Pulmonary Rehabilitation only
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Green International University
Cystic Fibrosis
Comparison of Airway Clearance Efficacy of Two High Frequency Chest Wall Oscillation (HFCWO) Devices in Cystic Fibrosis
Patients with cystic fibrosis (CF) must perform daily bronchial drainage therapy (BD) to keep their airways clear of secretions.
- Trial name
- NCT00308958
- Testing
- High frequency chest wall oscillator
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Minnesota
Malignant Chest Wall Neoplasm, Recurrent Breast Carcinoma
Talimogene Laherparepvec in Treating Patients With Recurrent Breast Cancer That Cannot Be Removed by Surgery
This phase II trial studies how well talimogene laherparepvec works in treating patients with breast cancer that has come back and cannot be removed by surgery.
- Conditions
- Malignant Chest Wall Neoplasm, Recurrent Breast Carcinoma, Recurrent Inflammatory Breast Carcinoma, Stage IV Breast Cancer AJCC v6 and v7
- Trial name
- NCT02658812
- Testing
- Laboratory Biomarker Analysis, Talimogene Laherparepvec
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- M.D. Anderson Cancer Center
Respiratory Failure, Neuromuscular Disease
Ventilator Monitoring in Early Exacerbation Detection
The aim of this study is to determine whether respiratory disease exacerbations (a sudden worsening of symptoms) can be predicted by variables that are monitored by non-invasive ventilators (small machines that assist breathing)…
- Conditions
- Respiratory Failure, Neuromuscular Disease, Chest Wall Disorder, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT01644162
- Testing
- iVAPS ventilation
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- ResMed
Chest Wall Disorder
Three-dimensional Scanning of the Chest: a Comparison Between Three Different Imaging Modalities
Recently, three-dimensional scanning of the torso has been proposed as an alternative for two-view chest radiographies and computed tomography to determine the severity of pectus excavatum without exposure to ionizing radiation.
- Trial name
- NCT04279886
- Testing
- Three-dimensional scans
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Zuyderland Medisch Centrum
COPD
Continuous Chest Wall Vibration in COPD Rehabilitation
Dyspnea, the sensation of breathing discomfort or shortness of breath, is one of the main symptoms for patients affected by Chronic Obstructive Pulmonary Disease (COPD), particularly during exercise.
- Trial name
- NCT03644888
- Testing
- Cycle ergometer training, Airway clearance program, Vibration therapy
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Breast Cancer, Oncoplastic Breast Surgery
Scarless Advanced Breast Extended Oncoplasty: The ScarABEO Study
Breast conserving surgery followed by radiotherapy is the gold standard treatment for early breast cancer. Cases with unfavorable tumor volume to breast volume ratio or challenging localizations are at higher risk of margin…
- Conditions
- Breast Cancer, Oncoplastic Breast Surgery, Oncoplastic Breast-conserving Surgery, Chest Wall Perforator Flap
- Trial name
- ScarABEO (NCT06906237)
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Istituto Oncologico Veneto IRCCS
Preterm, Premature
Effects of Kinesiotaping on Respiratory Muscles in Very Preterm Infants
This study aimed to evaluate the effects of kinesio taping on blood gas parameters, respiratory rate, heart rate, oxygen saturation, and pressure limits in preterm infants with RDS who are on NIV.
- Conditions
- Preterm, Premature, Infant, Newborn, Diseases, Respiratory Distress Syndrome
- Trial name
- NCT06285669
- Testing
- kinesiotaping application
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Ondokuz Mayıs University
Ischemia, Angina
Comparison Of Left Ventricular Volume And Wall Stress With Dobutamine And Exercise Echocardiography
This study will compare the physiologic responses between exercise stress echocardiography and pharmacologic stress echocardiography on left ventricular volume and wall stress.
- Trial name
- NCT00774891
- Where
- United States
- Sponsor
- Lahey Clinic
Breast Cancer, Skin Cancer
Safety Study Using Photodynamic Therapy Light Therapy for Patients With Chest Wall Progression of Breast Cancer and Satellite Metastases of Melanoma
This research is intended to explore a new approach to therapy when breast cancer recurs in the skin. The treatment, known as continuous low-irradiance photodynamic therapy, or CLIPT, has shown great promise in animal studies.
- Trial name
- CLIPT (NCT00862901)
- Testing
- CLIPT patch
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Tufts Medical Center
Breast Cancer
MRI-Guided Ultrasound Stimulated Microbubbles Radiation Treatment for Patients with Chest-Wall and Locally Advanced Breast Cancer
The objective of this study is to demonstrate the feasibility of novel Magnetic Resonance Imaging (MRI)-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam…
- Trial name
- NCT06633601
- Testing
- MR-Guided Focused Ultrasound Technology, Definity Suspension for Injection
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Sunnybrook Health Sciences Centre