Clinical trials: Chest Wall Disorders
Neuromuscular Disorders, Chest Wall Disorders
Response to NonInvasive Mechanical Ventilation According to the Breathing Pattern
The purpose of this study is to determine whether breathing pattern (specifically the inspiratory time/total respiratory cycle value) has an influence over the response to the noninvasive mechanical ventilation.
- Conditions
- Neuromuscular Disorders, Chest Wall Disorders, Obesity Hypoventilation Syndrome (OHS)
- Trial name
- NCT01991535
- Testing
- Spontaneous Ventilation Mode, Controlled Ventilation Mode, Simulator Ventilation Mode
- Where
- Spain
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Cystic Fibrosis
Effects of High-Frequency Chest Wall Oscillation Combined With Concurrent Training on Cough,in Cystic Fibrosis Patients
This randomized clinical trial aims to evaluate the effects of high-frequency chest wall oscillation (HFCWO) combined with concurrent training on cough, sputum clearance, exercise tolerance, and respiratory muscle strength in…
- Trial name
- NCT07519460
- Testing
- High-Frequency Chest Wall Oscillation, Concurrent Training
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Kidney Disease
Inspiratory Muscle Training in Patients With End-stage Renal Disease
Background: Patients with chronic kidney disease on hemodialysis may have reduced diffusion capacity, lung function and gas exchange due to mechanical and hemodynamic changes in the respiratory system, and decreased respiratory…
- Trial name
- NCT02599987
- Testing
- POWERbreathe® Classic Light
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Universidade Federal de Pernambuco
Respiratory Failure, Neuromuscular Disease
Autotitrating Versus Standard Non-invasive Ventilation (NIV) in Acute Exacerbation of Respiratory Failure
The aim of the study is to compare the efficacy and tolerance of autotitrating non-invasive ventilation (NIV) versus standard NIV in patients admitted to hospital with acute exacerbation of chronic respiratory failure.
- Conditions
- Respiratory Failure, Neuromuscular Disease, Chest Wall Disorder, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT01174316
- Testing
- AutoVPAP™, VPAPIIIST-A™
- Where
- United Kingdom
- Sponsor
- ResMed
Chronic Obstructive Pulmonary Disease
ACBT and High Frequency Chest Wall Oscillations in COPD Patients
Chronic obstructive pulmonary disease (COPD) patients with mucus hyper secretion tend to demonstrate increased frequency of infective exacerbations and a steeper slope of decline in lung function.
- Trial name
- NCT05424133
- Testing
- High frequency chest wall oscillation, Active cycle of breathing
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Bronchiolitis
Treatment of Pediatric Bronchiolitis
Bronchiolitis (BQ) is the acute viral infection of the tract respiratory syndrome in infants that affects the bronchioles of babies under 24 months of age.
- Trial name
- NCT03835936
- Testing
- High frequency compression of the chest wall group, Manual maneuvers physiotherapy group
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Guadarrama Hospital
Decision Making, Shared, Stereotactic Body Radiation Therapy
Shared Decision Making on Radiation Dose for Lung Malignancies
A Patient Decision Aid (PtDA) is developed during a workshop in close collaboration with selected patients. The PtDA is subsequently used in the consultation between patient and physician to facilitate their shared decision on…
- Conditions
- Decision Making, Shared, Stereotactic Body Radiation Therapy, Lung Cancer, Non-small Cell, Radiation Toxicity
- Trial name
- NCT04940936
- Testing
- A Patient Decision Aid
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Vejle Hospital
Oral Cavity Cancer, Head and Neck Cancers - Tonsils
Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis
As mentioned above, several prior studies have shown the positive effects of oral use of aloe vera juice in managing chemotherapy and radiation-induced oral mucositis and esophagitis.
- Conditions
- Oral Cavity Cancer, Head and Neck Cancers - Tonsils, Esophageal Cancer, Laryngeal Cancer
- Trial name
- NCT05369234
- Testing
- 100% Aloe Vera Juice, Magic Mouthwash, Salt and Baking soda rinse
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Covenant Health Cancer Center
Lung Cancer
Efficacy Study of a Selective Chest Wall Restriction Belt in Postoperative of Lung Resection
The objective of this study is to evaluate the efficacy of a new medical device in post-surgery of lung resection. The principle of this new device is based on selective chest wall restriction.
- Trial name
- CTS-POP (NCT04369118)
- Testing
- Conventional follow-up, Conventional follow-up+chest wall restriction belt
- Where
- 3 sites in France
- Volunteers
- 94 people
- Sponsor
- University Hospital, Grenoble
Pain, Postoperative, Cardiac Surgery
Chest Wall Block After Sternotomy: Randomized Controlled Trial in Cardiac Surgery: (PABLOS Study)
The main objective is to compare the effectiveness of LocoRegional Anesthesia (LRA) (bilateral transverse thoracic block or bilateral parasternal block) in addition to standard management compared to standard management alone…
- Trial name
- PABLOS (NCT05345639)
- Testing
- LRA Loco-regional anesthesia, Standardized post-operative analgesia protocol
- Where
- France
- Volunteers
- 254 people
- Sponsor
- University Hospital, Angers
Headache, Cognitive Disturbance
Effects of IV-Administered Ca-DTPA and Zn-DTPA To Treat Patients With Gadolinium Deposition Disease
Purpose: There are two goals we have for this prospective single arm study; to see an increase in the amount of gadolinium in 24 hour urine collection following each infusion treatment with Calcium and Zinc DTPA, and to see a…
- Conditions
- Headache, Cognitive Disturbance, Skin Hyperpigmentation, Arthralgia
- Trial name
- NCT02947022
- Testing
- Calcium DTPA, Zinc DTPA
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of North Carolina, Chapel Hill
Ischemia, Angina
Comparison Of Left Ventricular Volume And Wall Stress With Dobutamine And Exercise Echocardiography
This study will compare the physiologic responses between exercise stress echocardiography and pharmacologic stress echocardiography on left ventricular volume and wall stress.
- Trial name
- NCT00774891
- Where
- United States
- Sponsor
- Lahey Clinic
Angina Pectoris, Left Ventricular Wall Motion Abnormalities
Hybrid Intraprocedural Imaging Based on 2 Different Imaging Methods
The investigators will check the feasibility of an intraprocedural vitality diagnostics and the identification of an indication for Percutaneous transluminal coronary angioplasty (PTCA).
- Trial name
- NCT01389674
- Testing
- 2D-strain echo
- Where
- Germany
- Sponsor
- RWTH Aachen University
Non-Cardiac Chest Pain, Undiagnosed Chest Pain
Non-cardiac Chest Pain Evaluation and Treatment Study (CARPA) - Part 1: Diagnosis.
The overall aim of the project is to evaluate diagnosis and treatment of chest pain originating from the musculoskeletal system.
- Conditions
- Non-Cardiac Chest Pain, Undiagnosed Chest Pain, Musculoskeletal Chest Pain, Ischemic Heart Disease
- Trial name
- NCT00373828
- Where
- Denmark
- Volunteers
- 302 people
- Sponsor
- Clinical Locomotion Science
End Stage Liver Diseases
Analysis of Respiratory System Mechanics and Inflammatory Response During Orthotopic Liver Transplantation (SPPLIT Trial)
During orthotopic liver transplantation (OLT), respiratory system function may be severely impaired for several reasons including anaesthesia effects, hyperdynamic volume state with fluid overload and ischemia reperfusion injury.
- Trial name
- SPPLIT (NCT02119585)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Turin, Italy
Cystic Fibrosis
High Frequency Chest Wall Oscillation and Cystic Fibrosis
High frequency chest wall oscillation (HFCWO) has been shown to increase tracheal mucus clearance compared with a control group.
- Trial name
- NCT01057524
- Testing
- High Frequency Chest Wall Oscillation (HFCWO), Usual airway clearance
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- Imperial College London
Stroke, Chest Wall Disorder
Addition of Proprioceptive Neuromuscular Facilitation to Cardio Respiratory Training Post Stroke
Post-stroke hemiparesis causes sequelae in the limbs and also in the trunk and abdomen structures. The level of physical activity decreases and cardiorespiratory training(CRT) is indicated to this population to improve the…
- Conditions
- Stroke, Chest Wall Disorder, Quality of Life
- Trial name
- NCT03171012
- Testing
- Lower limbs CRT, Upper limbs CRT, Proprioceptive Neuromuscular Facilitation
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Cerebral Palsy
Study Assessing High-Frequency Chest Wall Oscillation (HFCWO) in Preventing Pulmonary Exacerbations
To asssess efficacy of airway clearance provided by Vest therapy (HFCWO) in the reduction of respiratory exacerbations requiring hospitalization or antibiotic utilization in patients with muscle weakness and restrictive lung…
- Trial name
- NCT00739310
- Testing
- Vest Treatment (high frequency chest wall oscillation)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Hill-Rom
Acute Respiratory Failure, Pneumonia
HFCWO on Pneumonic Respiratory Failure
BACKGROUND: Endotracheal intubation and prolonged immobilization of patients receiving mechanical ventilation may reduce expectoration function.
- Trial name
- HFCWOonAFR (NCT02758106)
- Testing
- Vest Airway Clearance System Model 105
- Volunteers
- 73 people
- Sponsor
- Chung Shan Medical University
Airway Clearance Impairment
Comparisons of Two Airway Clearance Techniques
The goal of this clinical trial is to compare the effectiveness of two airway clearance techniques for patients with ventilator associated pneumonia.
- Trial name
- NCT06032871
- Testing
- high frequency chest wall oscillation, Chest physiotherapy
- Where
- 2 sites in Taiwan
- Volunteers
- 30 people
- Sponsor
- Hui-Ling Lin