Clinical trials: Chest Wall Tumor
Breast Cancer
A Novel Therapy for the Treatment of Chest Wall Progression of Breast Cancer
This study will assess safety and ergonomics/engineering design of a novel cancer treatment, Continuous Low Irradiance Photodynamic therapy (CLIPT).
- Trial name
- NCT01262716
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Rogers Sciences Inc.
Breast Cancer
Phase I/II Trial of Doxil and Hyperthermia for Breast Cancer Patients With Chest Wall Recurrence or Stage IV Disease With Locally Advanced Breast Cancer
Purpose: The purpose of this protocol is to evaluate the combination of Doxil chemotherapy and heat treatment for recurrent breast cancer located on the chestwall following mastectomy.
- Trial name
- NCT00006433
- Testing
- Doxil, heat treatment
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)
Amyloidosis, Basal Cell Carcinoma
The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
This phase II trial studies whether providing cancer treatment in the home is preferred over the traditional clinic setting and if it improves treatment satisfaction in cancer patients living in the Florida Panhandle and…
- Conditions
- Amyloidosis, Basal Cell Carcinoma, Biliary Tract Carcinoma, Bladder Carcinoma
- Trial name
- NCT07285044
- Testing
- Cancer Therapeutic Procedure, Questionnaire Administration
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Mayo Clinic
Chest Wall Tumor
Comparative Study on Different Bone Reconstruction After Chest Wall Tumor Resection
Chest wall tumors are one of the important diseases in thoracic surgery, and surgery is still the main treatment for this disease in clinical practice. Surgery for chest wall tumors requires extensive resection.
- Trial name
- NCT06994533
- Testing
- methods on bone reconstrucion after chest wall tumor resection
- Volunteers
- 50 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Endoscopic Breast Surgery, Benign Breast Tumors
Endoscopic Extirpation of Benign Breast Tumors Using a Lateral Chest Wall Incision
1. A new surgical method for breast surgery has been introduced, which involves the removal of benign breast tumors through endoscopic surgery, thereby avoiding noticeable scarring on the breast. 2.
- Trial name
- NCT06472700
- Testing
- No intervention
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Non Small Cell Lung Cancer
Pre-Operative Assessment of Chest Wall Invasion in NSCLC Using Pre-Operative, Surgeon Performed Ultrasound
Non-Small Cell Lung Cancer (75% of lung cancer) is associated with involvement of the parietal pleura and or chest wall (soft tissue and/or bone) in 5-8% of patients.
- Trial name
- CT0010 (NCT01206894)
- Testing
- Transthoracic Ultrasound
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Breast Cancer, Metastatic Breast Cancer
Toll-like Receptor (TLR) 7 Agonist, Cyclophosphamide, and Radiotherapy for Breast Cancer With Skin Metastases
This study is to find an optimal dose of Imiquimod (IMQ) in the first part (Phase I) and test the effectiveness of the combination treatment of IMQ, cyclophosphamide (CTX), and radiotherapy (RT) in patients with skin metastases…
- Conditions
- Breast Cancer, Metastatic Breast Cancer, Recurrent Breast Cancer
- Trial name
- NCT01421017
- Testing
- Radiation, Imiquimod, Cyclophosphamide
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- NYU Langone Health
Late Effects of Hypofractionated Radiotherapy in Breast Cancer
Late-term Effects of Hypofractionated Chest Wall and Regional Nodal Irradiation in Patients With Breast Cancer
Survival of breast cancer patients has improved with multimodality treatment. Hypofractionated radiotherapy (RT) is rapidly emerging as one of the options for breast cancer patients after breast conservation surgery (BCS) but…
- Trial name
- LEHR (NCT04175821)
- Testing
- Hypofractionated radiotherapy
- Volunteers
- 1,770 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Breast Cancer
Radiotherapy After Mastectomy for Breast Cancer Patients at Increased Risk of Local Recurrence
STUDY DESCRIPTION: This is a single-arm study to assess the feasibility, toxicity and cosmetic outcome of partial radiotherapy of the chest wall in breast cancer patients at increased risk of local relapse submitted to…
- Trial name
- NCT03101683
- Testing
- Partial chest wall radiation therapy
- Volunteers
- 28 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Chest Wall Tumor, Reconstruction Surgery
Artificial Intelligence Combined With 3D-Preformed Chest Wall Defection Reconstruction System in Chest Wall Tumor Surgery
Chest wall tumors should be completely resection as much as possible while malignant chest wall tumors should be extensively resection.
- Trial name
- AICW3DPCWDRS (NCT06978075)
- Testing
- Chest wall tumor resection by the artificial intelgent assistent
- Volunteers
- 50 people
- Sponsor
- Wu Weiming
Breast Cancer
Active Breathing Coordinator-based vs VisionRT-based Deep Inspiration Breath-hold for Radiation for Breast Cancer
Female patients treated with radiation for left-sided breast malignancy will undergo alternate fractions of Active Breathing Coordinator (ABC)-assisted and VisionRT-assisted Deep Inspiration Breath-Hold (DIBH).
- Trial name
- VisionRT (NCT02694029)
- Testing
- Active Breathing Coordinator (ABC), VisionRT
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Texas Southwestern Medical Center
Lung Cancer Patients, Non-small Cell Lung Cancer (NSCLC)
Treatment of Pulmonary SUlcus, Pancoast and Chest Wall Non-small Cell Lung Cancer Employing Radiation, Immuno-oncology and Resection
The SUPER trial is a prospective Phase II trial. It is designed for patients with stage 2 or 3 non-small cell lung cancer (NSCLC) prior to surgery.
- Trial name
- SUPER (NCT06331455)
- Testing
- Durvalumab, Non-ablative oligofractionated radiation (NORT)
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Marc de Perrot
Breast Cancer, Skin Cancer
Safety Study Using Photodynamic Therapy Light Therapy for Patients With Chest Wall Progression of Breast Cancer and Satellite Metastases of Melanoma
This research is intended to explore a new approach to therapy when breast cancer recurs in the skin. The treatment, known as continuous low-irradiance photodynamic therapy, or CLIPT, has shown great promise in animal studies.
- Trial name
- CLIPT (NCT00862901)
- Testing
- CLIPT patch
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Tufts Medical Center
Breast Cancer
Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Chest-wall and Breast Cancer
The objective of this study is to demonstrate the feasibility of novel MRI-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam radiotherapy delivered using a LINAC…
- Trial name
- USmBRT-B (NCT04431674)
- Testing
- Definity Suspension for Injection
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Sunnybrook Health Sciences Centre
Breast Cancer, Oncoplastic Breast Surgery
Scarless Advanced Breast Extended Oncoplasty: The ScarABEO Study
Breast conserving surgery followed by radiotherapy is the gold standard treatment for early breast cancer. Cases with unfavorable tumor volume to breast volume ratio or challenging localizations are at higher risk of margin…
- Conditions
- Breast Cancer, Oncoplastic Breast Surgery, Oncoplastic Breast-conserving Surgery, Chest Wall Perforator Flap
- Trial name
- ScarABEO (NCT06906237)
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Istituto Oncologico Veneto IRCCS
Pulmonary Neoplasm
Trial of Pre-operative Chemoradiotherapy Followed by Surgical Resection in Pancoast Tumors (JCOG 9806)
The purpose of this study is to evaluate the safety and efficacy of the trimodality (concurrent chemoradiotherapy followed by surgical resection) approach in superior sulcus tumors.
- Trial name
- NCT00128037
- Testing
- mitomycin C, vindesine, cisplatin and radiotherapy
- Where
- Japan
- Volunteers
- 75 people
- Sponsor
- Japan Clinical Oncology Group
Soft Tissue Sarcoma
Hypofractionated Pre-operative Radiation Therapy for Soft Tissue Sarcomas of the Extremity and Chest-wall
This is a nonrandomized Phase II pilot protocol to determine the feasibility, toxicity and disease control (local control, overall and progression-free survival) using hypofractionated preoperative radiation therapy in patients…
- Trial name
- NCT02634710
- Testing
- Hypofractionated Radiation Therapy
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Medical College of Wisconsin
Inflammatory Markers
Impact of Novel Thoracic Wall Blocks With Dexmetomidine on Inflammatory Markers Following Breast Cancer Surgery
The study will test the hypothesis that inflammatory markers measured at 24 hours after breast cancer surgery will be lower in patients receiving PECS II and PIFB blocks, supplemented with dexmetomidine compared to standard care…
- Trial name
- NCT04860115
- Testing
- Modified pectoralis block (PEC II) and pecto-intercostal fascial plane block (PIFB)
- Volunteers
- 120 people
- Sponsor
- St. Elizabeth Cancer Institute, Slovakia
Breast Cancer
Improving Quality of Life for Patients With Breast Cancer Invading the Chest Wall: A Prospective Registry For Patients Undergoing Full Thickness Chest Wall Resection
Although chest wall recurrence of breast cancer is uncommon, it represents a difficult clinical scenario. The role of full thickness chest wall resection (FTCWR) for breast cancer recurrence in the chest wall is controversial and…
- Trial name
- NCT03265379
- Testing
- FACT-B and Brief Pain Inventory
- Where
- Canada
- Volunteers
- 104 people
- Sponsor
- University Health Network, Toronto
Lung Cancer
Evaluation of Chronic Pain After Nerve Section During Thoracotomy
The purpose of this study is to investigate if controlled nerve section reduces chronic pain after thoracotomy.
- Trial name
- NCT00653367
- Testing
- Nerve section
- Where
- Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet