Clinical trials: Chest Wall Tumor
Endoscopic Breast Surgery, Benign Breast Tumors
Endoscopic Extirpation of Benign Breast Tumors Using a Lateral Chest Wall Incision
1. A new surgical method for breast surgery has been introduced, which involves the removal of benign breast tumors through endoscopic surgery, thereby avoiding noticeable scarring on the breast. 2.
- Trial name
- NCT06472700
- Testing
- No intervention
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Breast Neoplasms, Carcinoma, Ductal
Spect Analysis of Cardiac Perfusion Changes After Whole Breast/Chest Wall Radiation Therapy With ABC
Cardiac perfusion changes have been seen after whole breast / chest wall irradiation for breast cancer. The Active Breathing Coordinator (ABC) device theoretically decreases radiation exposure to the heart during radiation for…
- Conditions
- Breast Neoplasms, Carcinoma, Ductal, Adenocarcinoma
- Trial name
- NCT00321048
- Testing
- Active Breathing Coordinator
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Breast Cancer, Breast Cancer Female
Partial Chest Wall Radiation Therapy After Surgery for Lymph Node Negative Breast Cancer
The standard treatment for breast cancer when cancer cells were found near or within the margins of the tissue that is removed during breast surgery, is radiation of the entire chest wall.
- Conditions
- Breast Cancer, Breast Cancer Female, DCIS, Stage II Breast Cancer
- Trial name
- NCT05436808
- Testing
- Partial Chest Wall Radiation Therapy
- Where
- United States
- Sponsor
- Stony Brook University
Chronic Pain, Erector Spinea Plane Block
Tramadol Hydrochnoride as Adjuvant to Local Anesthetic in Ultrasound Guided Erector Spinea Plane Block in Management of Chronic Chest Wall Cancer Pain
Chest wall pain is a severe and distressing symptom. The erector spinae plane block (ESPB) is an interfascial plane block where local anesthetic is injected between the erector spine muscle and the transverse process.
- Trial name
- NCT04639154
- Testing
- Erector spinea plane block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Esophageal Cancer, Lung Cancer
Dexmedetomidine and Hypoxic Pulmonary Vasoconstriction in Thoracic Surgical Procedures and One-Lung Ventilation
The purpose of this study is to evaluate the effects of Dexmedetomidine when used during thoracic surgery. The primary outcome will be changes in oxygenation as measured the PaO2 during one lung ventilation.
- Conditions
- Esophageal Cancer, Lung Cancer, Chest Wall Disorders
- Trial name
- Dex-One-Lung (NCT00839605)
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Missouri-Columbia
Breast Cancer
Radiotherapy After Mastectomy for Breast Cancer Patients at Increased Risk of Local Recurrence
STUDY DESCRIPTION: This is a single-arm study to assess the feasibility, toxicity and cosmetic outcome of partial radiotherapy of the chest wall in breast cancer patients at increased risk of local relapse submitted to…
- Trial name
- NCT03101683
- Testing
- Partial chest wall radiation therapy
- Volunteers
- 28 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Breast Cancer
Improving Quality of Life for Patients With Breast Cancer Invading the Chest Wall: A Prospective Registry For Patients Undergoing Full Thickness Chest Wall Resection
Although chest wall recurrence of breast cancer is uncommon, it represents a difficult clinical scenario. The role of full thickness chest wall resection (FTCWR) for breast cancer recurrence in the chest wall is controversial and…
- Trial name
- NCT03265379
- Testing
- FACT-B and Brief Pain Inventory
- Where
- Canada
- Volunteers
- 104 people
- Sponsor
- University Health Network, Toronto
Breast Cancer
Veliparib With Radiation Therapy in Patients With Inflammatory or Loco-regionally Recurrent Breast Cancer
The purpose of this study is to determine the maximum tolerated dose of veliparib that can be given while a patient is receiving radiation therapy.
- Trial name
- NCT01477489
- Testing
- Veliparib, Standard radiation treatment
- Where
- 5 sites in United States
- Volunteers
- 33 people
- Sponsor
- University of Michigan Rogel Cancer Center
Malignant Chest Wall Neoplasm, Recurrent Breast Carcinoma
Talimogene Laherparepvec in Treating Patients With Recurrent Breast Cancer That Cannot Be Removed by Surgery
This phase II trial studies how well talimogene laherparepvec works in treating patients with breast cancer that has come back and cannot be removed by surgery.
- Conditions
- Malignant Chest Wall Neoplasm, Recurrent Breast Carcinoma, Recurrent Inflammatory Breast Carcinoma, Stage IV Breast Cancer AJCC v6 and v7
- Trial name
- NCT02658812
- Testing
- Laboratory Biomarker Analysis, Talimogene Laherparepvec
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer
MRI-Guided Ultrasound Stimulated Microbubbles Radiation Treatment for Patients with Chest-Wall and Locally Advanced Breast Cancer
The objective of this study is to demonstrate the feasibility of novel Magnetic Resonance Imaging (MRI)-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam…
- Trial name
- NCT06633601
- Testing
- MR-Guided Focused Ultrasound Technology, Definity Suspension for Injection
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Sunnybrook Health Sciences Centre
Breast Cancer
Postoperative Radiation of Patients With Breast Cancer in Extreme Hypofractionation.
Evaluation of treatment toxicity of extreme hypofractionation of the whole breast in five fractions of 5.2 Gy in five consecutive workdays.
- Trial name
- NCT05452083
- Volunteers
- 100 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Chest Wall Tumor
Comparative Study on Different Bone Reconstruction After Chest Wall Tumor Resection
Chest wall tumors are one of the important diseases in thoracic surgery, and surgery is still the main treatment for this disease in clinical practice. Surgery for chest wall tumors requires extensive resection.
- Trial name
- NCT06994533
- Testing
- methods on bone reconstrucion after chest wall tumor resection
- Volunteers
- 50 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Breast Cancer
Immediate Implant Breast Reconstruction
The purpose of this study is to study the impact of the immediate implant breast reconstruction for patients with mastectomy and postoperative chest wall radiotherapy
- Trial name
- ISIS (NCT02055937)
- Testing
- immediate implant breast reconstruction
- Where
- France
- Volunteers
- 53 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Chest Wall Tumor
RISI in the Treatment of Recurrent Chest Wall Malignancies After EBRT
This study will observe the efficacy and toxicities of 3-dimensional printing noncoplanar template assisted CT guided radioactive iodine-125 seeds implantation in the treatment of patients with recurrent chest wall malignancies…
- Trial name
- NCT04077710
- Testing
- Radioactive Iodine-125 Seeds Implantation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University Third Hospital
Mastectomy, Modified Radical
Paravertebral Block (PVB) Combined Pectoral Musculature Blocks for Modified Radical Mastectomy (MRM)
Previous studies have shown that PVB reduces pain and postoperative nausea and vomiting after breast cancer surgery when used in addition to general anesthesia or sedation.
- Trial name
- NCT02747992
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Breast Cancer
2-weeks of Adjuvant Radiotherapy in Patients With Breast Cancer
The investigators at PGIMER have been practicing hypofractionation radiotherapy with a dose of 35Gy/15#/3wks to the chest wall in post mastectomy and 40Gy/16#/3wks in breast conservation in breast cancer patients for the last 4…
- Trial name
- NCT02460744
- Testing
- Hypofractionation
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Sarcoma, Soft Tissue Sarcomas
Clinical Study of Concurrent Pazopanib and Radiotherapy for Non-metastatic Sarcoma Patients
Radiotherapy (RT) alone is able to induce a clinically significant effect with a variable pathologic response (a pathological complete remission, pCR, defined as ≥ 95%, or ≤ 5% remaining visible tumour cells) in only about 10% of…
- Trial name
- PASART-2 (NCT02575066)
- Testing
- external beam radiotherapy, pazopanib
- Where
- 3 sites in Netherlands, United Kingdom
- Volunteers
- 25 people
- Sponsor
- The Netherlands Cancer Institute
Desmoid, Desmoid Fibromatosis of Skin
Doxorubicin Eluting Intra-arterial Embolization for Aggressive Desmoid Fibromatosis
In this study Drug-eluting microbeads (DEB) loaded with Doxorubicin will be delivered into the target Desmoid Fibromatoses (DF) tissue via selective arterial embolization by angiographic technique.
- Conditions
- Desmoid, Desmoid Fibromatosis of Skin, Desmoid Neoplasm of Chest Wall, Desmoid Tumor Caused by Somatic Mutation
- Trial name
- NCT03966742
- Testing
- Drug Eluting Bead Embolization (DEB) for Desmoid Fibromatosis
- Where
- Israel
- Volunteers
- 8 people
- Sponsor
- Rabin Medical Center
Esophageal Cancer, Esophagectomy
Oesophagectomy and Chest Wall and Respiratory Function
Open surgery for esophageal cancer commonly involves large incisions in the chest, associated with a high rate of pulmonary complications (30-50%).
- Conditions
- Esophageal Cancer, Esophagectomy, Respiratory Function Loss
- Trial name
- NCT03835273
- Testing
- 3D motion capture system, Incentive spirometry, Questionnaires
- Where
- United Kingdom
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Chest Wall Tumor, Reconstruction Surgery
Artificial Intelligence Combined With 3D-Preformed Chest Wall Defection Reconstruction System in Chest Wall Tumor Surgery
Chest wall tumors should be completely resection as much as possible while malignant chest wall tumors should be extensively resection.
- Trial name
- AICW3DPCWDRS (NCT06978075)
- Testing
- Chest wall tumor resection by the artificial intelgent assistent
- Volunteers
- 50 people
- Sponsor
- Wu Weiming