Clinical trials: Chest--Diseases
Lung Carcinoma
Tailoring Shared Decision Making for Lung Cancer Screening in Persons Living With HIV
This study tailors a shared decision making intervention for lung cancer screening in persons living with human immunodeficiency virus (HIV).
- Trial name
- NCT04682301
- Testing
- Behavioral Intervention, Discussion (focus group), Discussion (feedback on SDM)
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Lung Cancer
Co-Design and Pilot Testing of Peer-led Community Outreach to Improve Equity, Veteran-Centeredness and Uptake of Lung Cancer Screening
Co-design will be implemented to develop an innovative, Veteran-centered intervention (Vet Peer Connects program) that meets the needs of Black Veterans.
- Trial name
- VPC (NCT06389981)
- Testing
- Veterans peer connect Program
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Acute Coronary Syndrome, Depression
MBCT Delivered Via Group Videoconferencing for ACS Patients With Elevated Depression Symptoms
The objective of this study is to identify Acute Coronary Syndromes (ACS) patients' specific needs and preferences for depression treatment via in-person or virtual individual interviews to (a) guide MBCT adaptation; and identify…
- Conditions
- Acute Coronary Syndrome, Depression, Myocardial Infarction, Unstable Angina
- Trial name
- NCT03878160
- Testing
- Individual Interview
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pressure Ulcer
Comparison Between a Novel Proning Pillow System and Standard Pillows
During the COVID-19 pandemic, intensive care units (ICUs) across the country have been inundated with increasing numbers of COVID patients.
- Trial name
- NCT05149989
- Testing
- Proning Pillow System
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Breast Cancer, Lung Cancer
Developing a Virtual Stress Management Intervention for Spousal/Partnered Caregivers of Solid Tumor Cancer Patients.
This randomized control trial will investigate the ability of an effective stress management psychoeducation program for employed caregivers to mitigate psychological distress and pathophysiology in spousal or partnered…
- Conditions
- Breast Cancer, Lung Cancer, Colon Cancer, Solid Tumor, Adult
- Trial name
- eCare (NCT04739696)
- Testing
- PEPRR, Pep-Pal
- Where
- United States
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Breast Neoplasms, Carcinoma, Ductal
Spect Analysis of Cardiac Perfusion Changes After Whole Breast/Chest Wall Radiation Therapy With ABC
Cardiac perfusion changes have been seen after whole breast / chest wall irradiation for breast cancer. The Active Breathing Coordinator (ABC) device theoretically decreases radiation exposure to the heart during radiation for…
- Conditions
- Breast Neoplasms, Carcinoma, Ductal, Adenocarcinoma
- Trial name
- NCT00321048
- Testing
- Active Breathing Coordinator
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Coronary Artery Disease, Ischemic Heart Disease
Volatilome and Single-Lead Electrocardiogram Optimize Ischemic Heart Disease Diagnosis Using Machine Learning Models
This is a prospective, case-control, single-center, observational, non-randomized study. It is designed to evaluate the diagnostic accuracy of functional tests involving physical exertion monitored via a 12-lead ECG, combined…
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Chronic Coronary Disease, Angina Pectoris
- Trial name
- NCT06181799
- Testing
- Mass spectrometry using the PTR TOF-1000 (IONICON PTR-TOF-MS - Trace VOC Analyzer, Eduard-Bodem-Gasse 3, 6020 Innsbruck, Austria (Europe).
- Where
- Russia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Thoracic Diseases, Postoperative Pain
Minimally Invasive Thoracic Surgery Intercostal Nerve Block Trial
The Minimally Invasive Thoracic Surgery Intercostal Nerve Block Trial is a single center, double-blind, randomized, active-comparator controlled clinical trial to assess the analgesic efficacy of intercostal nerve block by…
- Conditions
- Thoracic Diseases, Postoperative Pain, Opioid Use
- Trial name
- NCT03508830
- Testing
- Liposomal bupivacaine, Bupivacaine Injection
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cardiac Arrest
Bystander Fatigue and CPR Quality Using Continuous Compressions Versus 30:2 Compressions to Ventilation
STUDY OBJECTIVES The overall goal of this study is to compare bystander fatigue and CPR quality after 5 minutes of continuous chest compressions versus the 2005 30:2 chest compression to ventilation Resuscitation Guidelines, in a…
- Trial name
- NCT01397656
- Testing
- CPR using 30:2 ratio, CPR using continuous compressions
- Where
- Canada
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Pectus Excavatum
Multicenter Trial of Magnetic Mini-Mover for Pectus Excavatum
This study is a Phase 3, multicenter, non-randomized study to evaluate the safety and efficacy of the next-generation outpatient Magnetic Mini-Mover Procedure (3MP) in 15 patients aged 8-14 years for the correction of pectus…
- Trial name
- 3MP (NCT01327274)
- Testing
- Magnetic Mini-Mover Procedure (Magnimplant)
- Where
- 3 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Michael Harrison
Lung Cancer, Pneumothorax
Outpatient Chest Tube Management Following Thoracic Resection Improves Patient Length of Stay and Satisfaction Without Compromising Outcomes
Discharging patients home with air leak and chest tube to portable drainage device after thoracic resection is cost effective and safe without compromising patients outcome or satisfaction.
- Conditions
- Lung Cancer, Pneumothorax, Subcutaneous Emphysema
- Trial name
- NCT01551082
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Alliance of Cardiothoracic and Vascular Surgeons
Atrial Fibrillation, Pericardial Effusion
Active Clearance of Chest Tubes After Cardiac Surgery: A Prospective Randomized Controlled Study
The purpose of this study is to assess the effectiveness of the PleuraFlow® Active Tube Clearance (ATC) technology in reducing the rate of postoperative atrial fibrillation (POAF) among post cardiac surgery patients and to…
- Conditions
- Atrial Fibrillation, Pericardial Effusion, Pleural Effusion, Hemothorax
- Trial name
- NCT02808897
- Testing
- Standard drainage, Active Tube Clearance drainage
- Where
- 2 sites in Canada
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Montreal Heart Institute
Lung Cancer, Smoking Cessation
Shared Decision Making in Rural Primary Care Lung Cancer Screening and Smoking Cessation
The intervention is aimed to improve adherence to the lung cancer screening (LCS) guidelines and Centers for Medicare and Medicaid Services (CMS) coverage criteria to conduct shared decision-making (SDM) and provide smoking…
- Trial name
- SDM-LCS-SC (NCT04897568)
- Testing
- Patient decision aid
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Lung Carcinoma
Risk and Benefits of Electronic Cigarettes to Older Smokers at High Risk for Lung Cancer
This clinical trial investigates the effects of switching from smoking regular cigarettes to electronic cigarettes (e-cigarettes) among older adult smokers at high risk for lung cancer.
- Trial name
- NCT05144542
- Testing
- Nicotine Replacement
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Pectus Excavatum
Magnetic Mini-Mover Procedure to Treat Pectus Excavatum
This is a medical research study. The study investigators have developed a method to gradually repair pectus excavatum (sunken chest) deformity by placing a magnet on the sternum (breastbone) and then applying an external…
- Trial name
- 3MP (NCT00466206)
- Testing
- Magnetic Mini-Mover Procedure (3MP), Magnatract (external magnet in a removable external brace), 3MP (Magnetic Mini-Mover Procedure)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Chest Pain
Impact on Management of the HEART Risk Score in Chest Pain Patients
Aim of this study is to quantify the impact of the use of the HEART risk score on patient outcome and on costs in patients with chest pain presenting at the emergency room, as compared to not using the score.
- Trial name
- HEART-Impact (NCT01756846)
- Testing
- usual care, use of HEART risk score
- Where
- 9 sites in Netherlands
- Volunteers
- 3,666 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Breast Cancer, Lung Cancer
Prospective Trial of Vaccine Responses Against Pneumococcus and Influenza in Adult Cancer Patients 65 Years of Age and Older
Infections due to influenza and pneumococcus can be very serious and cause death. Anyone can get these infections. However, some people are at greater risk from the disease, including people 65 and older, the very young, and…
- Conditions
- Breast Cancer, Lung Cancer, Prostate Cancer
- Trial name
- NCT00741039
- Testing
- inactivated influenza vaccine and the 23- valent pneumococcal vaccine, inactivated influenza vaccine and the PPV23 vaccine (Pneumovax)
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Lung Cancer
The INSPIRE-Lung Study
LungTalk and leveraging Facebook-targeted Advertisement (FBTA) addresses the call to develop and test multi-level, cancer communication interventions using innovative methods and designs.
- Trial name
- NCT05824273
- Testing
- LungTalk, Non-tailored intervention - Standard of practice
- Where
- United States
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Hackensack Meridian Health
Lung Carcinoma, Tobacco Use Disorder
Intermittent or Continuous Acetylsalicylic Acid and Gene Expression in the Nasal Tissue of Current Smokers
This randomized phase II trial studies the safety and effects of acetylsalicylic acid (aspirin) taken continuously or intermittently on gene expression in the nasal tissue of current smokers.
- Trial name
- NCT02123849
- Testing
- Aspirin, Laboratory Biomarker Analysis
- Where
- 2 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Lung Cancer
Testing Informed Decision Making in Lung Cancer Screening
Lung cancer screening rates are very low despite the fact that lung cancer screening could save many lives. People need to understand the risks and benefits to screening as well as their own beliefs about screening.
- Trial name
- TIDiL (NCT04940221)
- Testing
- Shared Decision Making
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services