Clinical trials: Chest--Diseases
Pneumothorax Spontaneous Primary, Pneumothorax Spontaneous Secondary
Chest Drain Insertion Assisted by Virtual Reality
Clinical study aiming to investigate the potential benefit of the use of virtual reality helmet as a distractor during chest drain insertion to alleviate patients\' pain and anxiety
- Conditions
- Pneumothorax Spontaneous Primary, Pneumothorax Spontaneous Secondary, Pleural Effusion
- Trial name
- CASVIA (NCT06589739)
- Testing
- Virtual Reality Headset
- Volunteers
- 40 people
- Sponsor
- Central Hospital, Nancy, France
Refractory Angina Pectoris, Spinal Cord Stimulation
Efficacy of Spinal Cord Stimulation in Patients With Refractory Angina Pectoris
There are a growing number of patients with refractory angina pectoris (RAP). RAP is defined as a 'chronic condition (> three months) characterized by diffuse coronary artery disease in the presence of proven ischemia, which is…
- Trial name
- SCRAP (NCT04915157)
- Testing
- Spinal Cord Stimulator
- Where
- Netherlands
- Volunteers
- 72 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Aortic Aneurysm
ANCHOR (Aneurysm Treatment Using the Heli-FX™ EndoAnchor™ System Global Registry)
The ANCHOR registry is a multi-center, post-market, non-interventional, non-randomized, prospective study. Subjects must sign an ICF prior to obtaining any study specific information.
- Trial name
- ANCHOR (NCT01534819)
- Testing
- EndoAnchor™, endovascular treament
- Where
- 87 sites in United States, Australia and 11 more
- Volunteers
- 1,090 people
- Sponsor
- Medtronic Cardiovascular
Non-Small Cell Lung Cancer
Marker Guided Breathhold Radiotherapy in NSCLC
Proof of concept study evaluating safety and performance of a gel marker (BioXmark) used for image guidance in deep inspiration breathhold radiotherapy (DIBH IGRT) in patients with locally advanced non-small cell lung cancer…
- Trial name
- NCT02447900
- Testing
- BioXmark
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Steen Riisgaard Mortensen
Pleural Mesothelioma Malignant
Identification of Prognostic and Predictive Biomarkers of Toxicity in Patients With Malignant Pleural Mesothelioma and Treated With High Doses of Radiotherapy (MESORTIBO)
Malignant pleural mesothelioma (MPM) is a tumour that originates from the pleural layers (visceral and parietal) that envelop the lungs and the inner wall of the thoracic cage.
- Trial name
- MESORTIBO (NCT06637345)
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Centro di Riferimento Oncologico - Aviano
Lung Cancer
The Role of Interventional Pulmonology, Microbiota and Immune Response in the Patient With Lung Cancer
This study is designed to evaluate complications, specificity, diagnostic yield of radial endobronchial ultrasound guided transbronchial cryobiopsy and transbronchial forceps biopsy with fluoroscopy in the diagnosis of peripheral…
- Trial name
- RIPMIRLC (NCT05164445)
- Testing
- Transbronchial forceps biopsy, Transbronchial forceps biopsy+Transbronchial cryobiopsy
- Where
- Lithuania
- Volunteers
- 200 people
- Sponsor
- Lithuanian University of Health Sciences
Lung Cancer
Adaptation and Pilot Testing of a Lung Cancer Screening Decision Aid for Patients From a Safety-Net Healthcare System
The goal of the study is to adapt and test a participant decision aid about lung cancer screening for use with patients in theHarris Health System (HHS).
- Trial name
- NCT07382557
- Testing
- Surveys, Focus groups, Cognitive Interviews
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Carcinoma, Non-Small-Cell Lung
Stage III NSCLC RWE in Chinese Patients
The objectives of this study are to assess molecular testing, treatment patterns and associated clinical outcomes in Chinese patients with treatment-naïve stage III non-small cell lung cancer (NSCLC) in real world setting.
- Trial name
- NCT04023812
- Where
- 25 sites in China
- Volunteers
- 500 people
- Sponsor
- AstraZeneca
Pneumothorax Spontaneous Primary, Pneumothorax Spontaneous Secondary
Comparison of Talc Slurry Versus Talc Insufflation: A Study on Effectiveness, Safety, and Hospital Outcomes in Pleurodesis
Pleural effusion is characterized by the accumulation of fluid in the pleural space, which typically contains about 10-20 mL of pleural fluid that is crucial for the movement of the lungs against the chest wall.
- Conditions
- Pneumothorax Spontaneous Primary, Pneumothorax Spontaneous Secondary, Pleural Effusion, Malignant, Pleurodesis
- Trial name
- NCT07167992
- Testing
- Pleurodesis
- Where
- Pakistan
- Volunteers
- 160 people
- Sponsor
- University of Health Sciences Lahore
Non-small Cell Lung Cancer
A Study to Explore Clinical Characteristics and Prognoses of N2 Patients With Non-small Cell Lung Cancer
A study to compare patient survivals in the N2 patients with non-small cell lung cancer in the subgroups of lymph skip metastases and non-skip metastases
- Trial name
- NCT03429192
- Testing
- Surgery
- Where
- 9 sites in China
- Volunteers
- 2,653 people
- Sponsor
- Tianjin Chest Hospital
Non-small Cell Lung Cancer Stage II, Non-small Cell Lung Cancer Stage I
SBRT With Immunotherapy in Early Stage Non-small Cell Lung Cancer: Tolerability and Lung Effects
This is a single arm, multi-centre, phase II open label study of nivolumab with stereotactic body radiotherapy (SBRT) for early stage non-small cell lung cancer.
- Trial name
- STILE (NCT03383302)
- Testing
- Stereotactic body radiotherapy, Nivolumab
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Pulmonary Nodules
Intelligent Support for Radiological Reporting of Lung Neoplasms
Lung cancer is one of the most common cancers and has one of the worst prognoses, mainly due to the difficulty of early diagnosis.
- Trial name
- SPOILERS (NCT07360145)
- Testing
- Collection of variables identified for the study
- Where
- Italy
- Volunteers
- 329 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Pulmonary Nodules, Lung Neoplasms
Longitudinal AI-Assisted Management of Indeterminate Pulmonary Nodules
Patients with indeterminate lung nodules often face a choice between continued CT surveillance and invasive investigation. This trial compares management with or without access to an AI report that matches nodules across real…
- Trial name
- NCT07895277
- Testing
- AI-Assisted Longitudinal CT Assessment and Pulmonary Nodule Management
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Non Small Cell Lung Cancer
Preconditioning Chemotherapy Combination With Cytokine Induced Killer Cell (CIK) Immunotherapy
This clinical Trial is proposed to explore whether preconditioning chemotherapy of Paclitaxel+cisplatin(TP)regimen combined with autologous adoptive CIK cell immunotherapy could benefit NSCLC patients with a better clinical…
- Trial name
- NCT01902875
- Testing
- Paclitaxel + Cisplatin, CIK cell therapy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jinling Hospital, China
Adult Solid Tumor
CANscriptTM Clinical Outcomes in a Real-World Setting (ANCERS)-2
The purpose of this study is to test the CANscript™ sensitivity assay, which is a new and different assay developed to test the sensitivity of different cancer types to physician selected therapies (both drugs and/or drug…
- Trial name
- ANCERS-2 (NCT03253575)
- Testing
- CANscript
- Where
- 30 sites in United States
- Volunteers
- 800 people
- Sponsor
- Mitra RxDx, Inc.
Lung Cancer
PET/MR Imaging in Lung Cancer
The purpose of this project is to investigate if PET/MR imaging improves the accuracy in visualization and characterization of lung cancer disease, compared to PET/CT.
- Trial name
- NCT03739281
- Testing
- PET/MR, PET/CT
- Where
- Norway
- Volunteers
- 35 people
- Sponsor
- University Hospital of North Norway
Respiratory Distress, Lung Injury
Infant Pulmonary Mechanics: High Flow Nasal Cannula Versus Nasal CPAP
This study is designed to evaluate the effect of heated humidified high flow nasal cannula (HHHFNC) as compared to noninvasive nasal continuous positive airway pressure (NCPAP) on lung function as a measure of lung injury in…
- Trial name
- NCT01939067
- Testing
- Heated Humidified High Flow Nasal Cannula, Nasal Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Lung Cancer, Non-Small Cell
A Single-Arm, Phase Ⅰb Study of Golidocitinib Combined With Anti-PD-1 for the Treatment of Previously Treated NSCLC
This study is a phase Ib, single-center, single-arm exploratory clinical study designed to evaluate the safety and efficacy of Golidocitinib in combination with anti-PD-1 monoclonal antibody in locally advanced or metastatic…
- Trial name
- NCT06690671
- Testing
- Golidocitinib in combination with anti-PD-1
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Chest Hospital
Lung Cancer
Reveal the Patterns of Presentation, Management and Outcome of Patients With SCLC and Stage III NSCLC in Saudi Arabia:
A retrospective, multi-centre, observational study to describe the treatment patterns, the demographic, clinical outcomes, treatment effectiveness, and healthcare resource utilization (HCRU) for patients diagnosed with primary…
- Trial name
- REVEAL (NCT04836975)
- Where
- Saudi Arabia
- Volunteers
- 45 people
- Sponsor
- AstraZeneca
Lung Neoplasms
Efficacy and Safety of Sintilimab With or Without Radiotherapy in Patients With Recurrent or IV NSCLC (EGFR -, ALK -) After Failure of Platinum-based Chemotherapy: A Randomized,Open Labled, Phase II Clinical Study
Lung cancer incidence and mortality have been increasing steeply in the past thirty years in the mainland of China. More than 80% of lung cancer is non-small cell lung cancer (NSCLC).
- Trial name
- NCT04513301
- Testing
- Sintilimab, Radiotherapy
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Shanghai Cancer Hospital, China
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