Clinical trials: Child, Only
Children, Only
Ingestion Effect of Formula Milk With Triple Bifidobacteria Strains on Fecal Quality and Metabolites in Healthy Children
The goal of this clinical trial is to compare healthy children between 1 to 3 years old. The main question it aims to answer is 1.
- Trial name
- NCT06044376
- Testing
- Formula milk with triple Bifidobacterium probiotic strain, Formula milk
- Where
- 10 sites in Indonesia
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Respiratory Syncytial Virus (RSV)
Safety and Immunogenicity of a Single Dose of the Recombinant Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccines RSV ΔNS2/Δ1313/I1314L, RSV 6120/ΔNS2/1030s, RSV 276 or Placebo, Delivered as Nose Drops to RSV-Seronegative Children 6 to 24 Months of Age
The purpose of this study was to evaluate the safety and immunogenicity of a single dose of the recombinant live-attenuated respiratory syncytial virus (RSV) vaccines, RSV ΔNS2/Δ1313/I1314L, RSV 6120/ΔNS2/1030s, and RSV 276, in…
- Trial name
- NCT03916185
- Testing
- RSV ΔNS2/Δ1313/I1314L Vaccine, RSV 6120/ΔNS2/1030s Vaccine, RSV 276 Vaccine
- Where
- 14 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Myopia
Low-dose Atropine for the Prevention of Myopia Progression in Danish Children
Myopia (nearsightedness) is increasing in prevalence throughout the world. It is associated with a risk of potentially blinding complications such as retinal detachment and myopic maculopathy.
- Trial name
- APP (NCT03911271)
- Testing
- 0.1% atropine and 0.01% atropine, 0.01% atropine, 0.9% Sodium-chloride
- Where
- 3 sites in Denmark
- Volunteers
- 97 people
- Sponsor
- Line Kessel
Vitamin D Deficiency, Stem Cell Transplant Complications
A Randomized Phase IV Control Trial of Single High Dose Oral Vitamin D3 in Pediatric Patients Undergoing HSCT
Research has suggested that children with sufficient vitamin D levels undergoing hematopoietic stem cell transplant (HSCT) have improved outcomes, including lower incidences of infection and graft-versus-host disease (GVHD), as…
- Conditions
- Vitamin D Deficiency, Stem Cell Transplant Complications, Pediatric Cancer, Blood Disorder
- Trial name
- NCT03176849
- Testing
- Vitamin D3, Standard Vitamin D3 Supplementation
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Phoenix Children's Hospital
Meningococcal Immunization, Healthy Volunteers
Safety and Immunogenicity of an Investigational Pentavalent Meningococcal ABCYW Vaccine Against Meningococcal Disease in Children, Toddlers, and Infants
This study is the first study of Sanofi's Pentavalent Meningococcal ABCYW vaccine clinical development program to be conducted in the pediatric population below 10 years of age.
- Trial name
- NCT06647407
- Testing
- Pentavalent Meningococcal ABCYW vaccine, MenACYW conjugate vaccine, Meningococcal group B vaccine
- Where
- 39 sites in Brazil, Czechia and 7 more
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Cholelithiasis, Biliary Dyskinesia
Single Incision Laparoscopic Surgery (SILS) Versus Laparoscopic Cholecystectomy
Prospective randomized trial of single incision versus standard 4 port laparoscopic cholecystectomy. Hypothesis is that the operative time will be longer with single incision.
- Trial name
- SILS (NCT00981604)
- Testing
- SILS, Standard Laparoscopic Cholecystectomy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Mercy Hospital Kansas City
Hearing Impaired Children, Hearing Impairment, Conductive
Single-stage Surgery Using the BI300 Implant
Over the last few decades, the classical two-stage surgical procedure for inserting bone-anchored hearing implants (BAHIs) has been modified in adults into a single-stage procedure.
- Trial name
- NCT04038216
- Testing
- Single-stage surgery, Two-stage surgery
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Radboud University Medical Center
Hereditary Angioedema (HAE)
A Pharmacokinetic, Tolerability and Safety Study of Icatibant in Children and Adolescents With Hereditary Angioedema
HGT-FIR-086 is a multicenter, open-label, non-randomized, single-arm study to evaluate the Pharmacokinetics, tolerability,safety, and efficacy on reproductive hormones, of a single subcutaneous (SC) administration of icatibant in…
- Trial name
- NCT01386658
- Testing
- icatibant
- Where
- 26 sites in United States, Australia and 8 more
- Volunteers
- 32 people
- Sponsor
- Shire
Down Syndrome
How Simplified Language Affects Comprehension and Learning in Young Children With Down Syndrome
The long-term study goal is to experimentally evaluate the components (and likely active ingredients) of early language interventions for young children with Down syndrome (DS).
- Trial name
- NCT06951516
- Testing
- Linguistic simplification
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Michigan State University
Physical Disability, Physical Activity
Frame Running for Exercise and Participation for Children and Young People With Physical Disabilities
The goal of this quasi-experimental single-arm trial is to evaluate whether a structured Frame Running training program can improve functional ability, participation, and quality of life in children and young people with physical…
- Conditions
- Physical Disability, Physical Activity, Physical Function, Quality of Life
- Trial name
- FRAME-EX (NCT07543614)
- Testing
- Frame Running Training
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- Odense University Hospital
High Myopia, Axial Length
Repeated Low-Level Red-Light Therapy Shortens Axial Length
The purpose of this clinical trial is to investigate the incidence and magnitude of axial length shortening after repeated low-level red-light therapy in high myopia children and teenagers.
- Conditions
- High Myopia, Axial Length, Eye Diseases
- Trial name
- NCT05768152
- Testing
- RLRL
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Second People's Hospital of Foshan
Hepatic Impairment
Effect of Mild Hepatic Impairment on the Pharmacokinetics of Istradefylline
The purpose of this study is to test whether mild liver impairment affects blood levels of istradefylline in humans. Decreased liver function could possibly increase istradefylline levels.
- Trial name
- NCT02256033
- Testing
- Istradefylline
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kyowa Kirin Co., Ltd.
Influenza
Safety and Immunogenicity of a Single Dose of Intranasal Seasonal Trivalent Live-Attenuated Influenza Vaccine
In this Phase II randomized controlled clinical trial, generally healthy male and female children from 24 through 59 months of age will be enrolled in Kamalapur (Dhaka), Bangladesh.
- Trial name
- NCT01625689
- Testing
- SIIL LAIV (live, trivalent seasonal influenza vaccine)
- Where
- Bangladesh
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- PATH Vaccine Solutions
Refractory Ascites, Children, Only
Safety and Efficacy of Midodrine Hydrochloride in the Management of Refractory Ascites Due to Cirrhosis in Children
Ascites in liver cirrhosis is explained by increased production of vasoactive substances leading to renal vasoconstriction and salt and water retention.
- Trial name
- NCT04043858
- Testing
- Midodrine 2.5 mg tab
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- National Liver Institute, Egypt
ADHD, Autism
Trial to Assess the Pharmacokinetics, Safety, Tolerability of Oral Brexpiprazole in Children (6 to <13 Years Old) With Central Nervous System Disorders
A study to assess pharmacokinetics, safety and tolerability of brexpiprazole in children ages 6 to <13 years with CNS disorders.
- Conditions
- ADHD, Autism, Bipolar I Disorder, Conduct Disorder
- Trial name
- NCT03292848
- Testing
- Brexpiprazole
- Where
- 9 sites in United States
- Volunteers
- 24 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Respiratory Syncytial Virus Infections
Safety and Immune Response to a Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccine in RSV-Seronegative Infants and Children
Respiratory syncytial virus (RSV) is a common cause of illness in infants and children around the world. This study will evaluate the safety and immune response to an RSV vaccine in RSV-seronegative infants and children.
- Trial name
- NCT02040831
- Testing
- RSV LID ΔM2-2 Vaccine
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Iron Deficiency Anemia (IDA), Nutrition Disorders
Nutritional Educational Program On Therapy in Iron Deficiency Anemia
The goal of this clinical trial is to evaluate whether a Nutritional Educational Program for caregivers can improve their knowledge and performance in managing iron deficiency anemia (IDA) in children, compared to oral iron…
- Conditions
- Iron Deficiency Anemia (IDA), Nutrition Disorders, Growth Retardation
- Trial name
- NEPOT-IDA (NCT06642337)
- Testing
- Educational program
- Where
- Iraq
- Volunteers
- 180 people
- Sponsor
- Hawler Medical University
Cystic Fibrosis in Children, Telerehabilitation
Virtual Reality Based Tele-Exercises on Exercise Capacity in Cystic Fibrosis
The goal of this clinical trial is to investigate the effects of a-12-week virtual reality exercise program, applied as tele-exercise, on the exercise capacity of children with cystic fibrosis, whose physical activity level is…
- Conditions
- Cystic Fibrosis in Children, Telerehabilitation, Virtual Reality
- Trial name
- NCT05850351
- Testing
- Virtual reality, Online
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Koç University
Conductive Hearing Loss, Single Sided Deafness
Use of ADHEAR, a Non-Implantable Bone Conduction Hearing System, in Children With Single Sided Deafness and/or Conductive Hearing Loss
A hearing loss affects the quality of life and the natural development of children. The new generation of hearing devices provides a huge number of options to them.
- Trial name
- NCT03327194
- Testing
- ADHEAR Audio Processor
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Queen Fabiola Children's University Hospital
Myopia
Red Light Intervention for Myopia Prevention
To explore the effectiveness of using low-intensity single-wavelength red light to prevent myopia in schoolchildren, and to provide a feasible scheme for reducing the incidence of myopia.
- Trial name
- NCT04825769
- Testing
- LLLT（Low Level Laser Therapy）
- Where
- China
- Volunteers
- 278 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center