Clinical trials: Child
Stress, Family
Evaluation of a Resiliency Program for Fathers of Children and Youth With Special Health Care Needs
Based on findings from our prior trials with parents of children with learning and attentional disabilities and parents of children with autism spectrum disorder (Kuhlthau et al., 2020; Park et al., 2020; IRB approved…
- Conditions
- Stress, Family, Fathers
- Trial name
- NCT05535348
- Testing
- Relaxation Response Resiliency Program for Father of CYSHCN
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Massachusetts General Hospital
Nasopharyngeal Neoplasms, Carcinoma
Docetaxel in Combination With Cisplatin-5-fluorouracil for the Induction Treatment of Nasopharyngeal Carcinoma in Children and Adolescents
The primary objective is to estimate the Complete Response rate of docetaxel to the combination of cisplatin-5-fluorouracil (TCF) compared to cisplatin-5-fluorouracil (CF) in the Induction treatment of Nasopharyngeal Carcinoma…
- Trial name
- NCT00565448
- Testing
- docetaxel, cisplatin, 5-fluorouracil
- Where
- 26 sites in Algeria, Brazil and 12 more
- Volunteers
- 75 people
- Sponsor
- Sanofi
Celiac Disease
Evaluate the Use of Optical Frequency Domain Imaging (OFDI) for Celiac Disease in Children, Adolescents and Young Adults
The goal of this research is to conduct a pilot clinical study to image Celiac disease characteristic mucosal lesions and compare Optical Frequency Domain Imaging (OFDI) images to histologic evaluation in children, adolescents…
- Trial name
- NCT01439035
- Testing
- MGH OFDI Imaging
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
ADHD
A Feasibility Study of a Support Program for Building New Parent-child Behavioral Habits
This study evaluates the feasibility and preliminary impacts of a new parent support program consisting of a series of educational videos, delivered via a popular texting platform.
- Trial name
- NCT06297135
- Testing
- Behavioral Parent Training
- Where
- 2 sites in Japan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Okinawa Institute of Science and Technology Graduate University
Bundle-Branch Block, Heart Septal Defects, Ventricular
Right Bundle Branch Block After Surgical Closure of Ventricular Septal Defect
The most common congenital heart disease is the ventricular septal defect, and after surgical closure of a such defect, an arrythmia called the right bundle branch block, is very frequent.
- Trial name
- NCT01480908
- Testing
- Echocardiography at rest, Echocardiography during exercise, MRI at rest
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pediatric Cancer
The Effect of Biofeedback-Based Virtual Reality Game on Children
The needles of port catheters, which are often used in childhood cancer treatment, must be changed every 5-7 days, which causes pain, anxiety, and fear in children every 5-7 days In recent years, the usage of virtual reality has…
- Trial name
- NCT05585840
- Testing
- Biofeedback-based virtual reality game
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Koç University
CHD - Congenital Heart Disease
Home-based Cardiovascular Rehabilitation in Young Patients With Congenital Heart Disease: the "Muscle Your Heart" Program
Standard cardiovascular rehabilitation is performed in a medical care and rehabilitation centre. However, it may not be adapted to the patient's profile and there are few medical care and rehabilitation centres specialized in…
- Trial name
- Muscletoncoeur (NCT07115589)
- Testing
- Muscle Your Heart home-based program
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Bordeaux
Congenital Heart Disease in Children
Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures
The incidence of moderate to severe congenital heart disease (CHD) in the United States is estimated to be 6 per 1000 live-born full term infants.
- Trial name
- NCT04604418
- Testing
- No intervention. It is observational
- Where
- 10 sites in United States, Canada
- Volunteers
- 10,000 people
- Sponsor
- Boston Children's Hospital
Cerebral Palsy, Traumatic Brain Injuries
Effects of an Adapted Ski/Snowboarding Program on Quality of Life in Children With Physical Disabilities
This study is assessing quality of life in children with a physical disability who participate in the Children's Hospital Colorado Hospital Sports Program (HSP), where children with physical disabilities are able to participate…
- Conditions
- Cerebral Palsy, Traumatic Brain Injuries, Spinal Cord Injuries, Physical Disability
- Trial name
- NCT02110290
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Colorado, Denver
Cerebral Palsy
Transplantation of Umbilical Cord-derived Mesenchymal Stem Cells Via Different Routes
To preliminarily evaluate the efficacy and safety of umbilical cord-derived mesenchymal stem cells (UC-MSCs), and compare the efficacy of UC-MSCs administered through the intravenous, intrathecal, and intranasal routes, in the…
- Trial name
- NCT03414697
- Testing
- Control group, UC-MSCs
- Where
- China
- Volunteers
- 44 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Body Dysmorhpic Disorder
Psychiatric Disorders in Dermatiological Diseases
The aim of this study: 1. Evaluate the presence of body dysmorphic disorder in children with dermatological diseases compared to healthy controls. 2.
- Trial name
- NCT07521813
- Testing
- Questionnaire and Physical Exam
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sohag University
Bipolar Spectrum Disorder
Open-Label Comparative Study of Risperidone Versus Olanzapine Versus Quetiapine for Mania in Children and Adolescents With Bipolar I and Bipolar II Disorder
The objective of this study is to compare the safety and effectiveness of Risperidone, Olanzapine, and Quetiapine in the treatment of mania in children and adolescents with Bipolar disorder over 8 weeks and then over an extension…
- Trial name
- NCT00182013
- Testing
- Risperidone, Olanzapine, Quetiapine
- Volunteers
- 106 people
- Sponsor
- Massachusetts General Hospital
Autism, Autistic Disorder
Use of Acupuncture In Children With Autistic Spectrum Disorder
This is a study of the efficacy of acupuncture in children with autism.
- Trial name
- NCT00352352
- Testing
- Tongue Acupuncture (Procedure)
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The University of Hong Kong
ADHD
KP415 Open-Label Safety Study in Children (6-12 Years of Age) With ADHD
This study is a multicenter, dose-optimized, open-label safety study with KP415 in children with Attention-Deficit/Hyperactivity Disorder (ADHD).
- Trial name
- NCT03460652
- Testing
- KP415 oral capsule
- Where
- 19 sites in United States
- Volunteers
- 282 people
- Sponsor
- Zevra Therapeutics
Cerebral Palsy
Correlation Between Clinical Measurement Scales for Gross Motor Function
Evaluating and applying an early and consistent rehabilitation approach to children with neurological impairments requires a multidisciplinary approach that involves different specialists, including pediatricians, pediatric…
- Trial name
- NCT06124352
- Testing
- Gross Motor Function Measurement - 66 (GMFM- 66), Bruininks- Oseretsky Motor Proficiency, the Peabody Developmental Motor Scale - Second Edition (PDMS-2
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
BPG Intervention, Control
Neurodevelopmental Assessment of Children in Uganda and Malawi Using a Software Package
The investigators will use Brain Power Games as a neurocognitive "stress test" or medical "challenge" test, in order to evaluate or improve brain/behavior functional integrity in HIV-affected children.
- Trial name
- NCT03878147
- Testing
- Cognitive Games Training
- Where
- 2 sites in Malawi, Uganda
- Volunteers
- 599 people
- Sponsor
- Michigan State University
Dental Caries in Children, Knowledge, Attitudes, Practice
The Effect of Oral Health Education on Knowledge, Attitude, Practice and Dental Caries Among Egyptian School Children
Aim of the study Assessing the effect of an oral health education program on knowledge, attitude, practice, and dental caries among a group of school children in a governmental school in Fayoum, Egypt.
- Trial name
- KAP (NCT06280547)
- Testing
- Oral health education
- Where
- Egypt
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Cairo University
Croup
A Cluster Controlled Trial Comparing Three Methods of Disseminating Practice Guidelines for Children With Croup
The purpose of this study is to identify, from a societal perspective, the costs and associated benefits of three strategies for disseminating and implementing a practice guideline that addresses the management of croup.
- Trial name
- NCT00147849
- Testing
- mailing of printed educational materials, a combination of interactive educational meetings, educational outreach visits, and reminders, identification of local opinion leaders and establishment of local consensus processes
- Sponsor
- Canadian Institutes of Health Research (CIHR)
Mother to Child Transmission, Breast Feeding
Trauma-informed Obstetric Care for Perinatal Health: a Pilot Study
The study will test trauma-informed obstetric care training and supervision for obstetric clinicians in relation to prenatal mental health and attachment formation (early predictors of child development) in women presenting for…
- Conditions
- Mother to Child Transmission, Breast Feeding, Trauma
- Trial name
- NCT07195058
- Testing
- Trauma Informed Obstetric Care (TIOC)
- Where
- Argentina
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Columbia University
Nephrotic Syndrome Steroid-Dependent, Nephrotic Syndrome Steroid-Resistant
Biomarkers and Outcome Predictors of Pediatric Nephrotic Syndrome: A Genetic, Transcriptomic, and Secretome Multiomics Study
Idiopathic Nephrotic Syndrome is a rare disease of the kidneys, which typically affects children. For most affected children there is the need of a prolonged treatment with drugs reducing the activity of the immune system, also…
- Conditions
- Nephrotic Syndrome Steroid-Dependent, Nephrotic Syndrome Steroid-Resistant, Nephrotic Syndrome in Children, Glomerulonephritis
- Trial name
- PRECISE (NCT06792448)
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico