Clinical trials: Child Birth
Mother to Child HIV Transmission
Evaluation of Measurement of Maternal Viral Load at Delivery to Optimise Post-natal Prophylaxis of HIV-exposed Newborns
The main objective is to evaluate the operationality of introducing the measurement of viral load in HIV-1 infected mothers at delivery by POC to optimise post-natal prophylaxis and neonatal diagnosis of children according to the…
- Trial name
- IPOP (NCT05017558)
- Testing
- point of care
- Where
- Guinea
- Volunteers
- 70 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Gross Motor Development Delay
Daily and Weekly Rehabilitation Delivery for Young Children With Gross Motor Delays
The purpose of this study is to determine the optimal frequency and intensity of physical therapy for children with cerebral palsy aged 6 to 24 months of age.
- Trial name
- DRIVE (NCT02857933)
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Ohio State University
Substance Use Disorders, Pregnancy Related
The Oklahoma Parent-Child Assistance Program
The Parent-Child Assistance Program (PCAP) helps mothers who have used alcohol, opioids, or other drugs during pregnancy and their children through the work of highly trained, closely supervised case managers.
- Conditions
- Substance Use Disorders, Pregnancy Related, Alcohol Use Disorder (AUD), Alcohol Use Complicating Pregnancy, First Trimester
- Trial name
- NCT05534568
- Testing
- Parent-Child Assistance Program
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Oklahoma
Congenital Disorders
Prevalence and Clinical Spectrum of the 22q11 Deletion
The purpose of this project is to conduct population based surveillance for prenatally diagnosed congenital defects amount residents of the five counties to: improve the comprehensiveness of the Metropolitan Atlanta Congenital…
- Trial name
- NCT00267397
- Where
- United States
- Sponsor
- Children's Healthcare of Atlanta
Short Stature Children Born Small for Gestational Age (SGA)
Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat SGA Children With Short Stature
The study was evaluated as the optimal dose for the treatment of SGA short stature children by Pegylated Somatropin, initially evaluated its efficiency and safety for the treatment of SGA short stature children and provided…
- Trial name
- NCT02375620
- Testing
- PEG-somatropin
- Where
- 9 sites in China
- Volunteers
- 96 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Low Birthweight, Preterm Birth
Enhancing Nutrition and Antenatal Infection Treatment for Maternal and Child Health in Ethiopia
The ENAT study will test the impact of packages of antenatal interventions to enhance maternal nutrition and manage pregnancy infections on the outcomes of infant birth size, gestational length, and infant growth in the first 6…
- Conditions
- Low Birthweight, Preterm Birth, Maternal; Malnutrition, Affecting Fetus, Sexually Transmitted Diseases
- Trial name
- ENAT (NCT04171388)
- Testing
- Azithromycin 500 mg, Multiple Micronutrient or Fortified Balanced Energy Protein Supplement, Enhanced Infection Management Package (EIMP)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Nutrition in Cancer Survival and Treatment
Delivery of Nutritional Services in Nicaragua
This study investigates nutritional status, at predefined points in therapy, and the association with outcomes in children and adolescents undergoing treatment for cancer in institutions under Asociación de Hemato-Oncología…
- Trial name
- NCT04031586
- Where
- Nicaragua
- Volunteers
- 50 people
- Sponsor
- Columbia University
Patient Compliance, Inhalation Spacers
Animated Cartoons and Cooperation in Young Children Receiving Inhaled Medications
Up to 50% of infants and young children cry during the administration of their inhaled treatment for their asthma. This results in decreased lung deposition, and thus decreased effectiveness of their inhaled treatment.
- Trial name
- DISTRACT (NCT02879240)
- Testing
- Animated Cartoon, Black screen
- Where
- 3 sites in France
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Hôpital Necker-Enfants Malades
Parenting, Child Behavior, Implementation
Systematically Adapted Delivery of the Family Check-Up
Early childhood disruptive behavior problems lead to significant costs to families and society, but can be reduced with behavioral parent training interventions.
- Trial name
- NCT02709291
- Testing
- behavioral parent training, interventionist training
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Christina Studts
Language Development
Language Development in Preterm Children
This research investigates the ways in which preterm birth affects how very young children learn to speak and understand language, and how older children gain efficiency in language processing.
- Trial name
- NCT01599780
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Stanford University
Bacterial Vaginosis, Fetal Membranes, Premature Rupture
Perinatal Infections in Pakistan
There are large differences in health outcomes related to pregnancy and birth between developed and developing countries. This study will investigate how infections, medical history, health care behavior and psychosocial issues…
- Conditions
- Bacterial Vaginosis, Fetal Membranes, Premature Rupture, Chorioamnionitis, Pregnancy
- Trial name
- NCT00070746
- Where
- Pakistan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Children Born Extremely Premature, Disturbance of Visuo-spatial Working Memory
Long-term Effects of Visual Spatial Working Memory Training Program Performed at Preschool Age in Very Preterm Infants With Visual Spatial Working Memory Deficit. A Randomized Controlled Trial
Prematurity tends to increase in France in recent years and more children born extremely premature infants survive. If severe impairments have stabilized, the majority of former extremely premature children have…
- Trial name
- EPIREMED (NCT02757794)
- Testing
- computerized cognitive remediation program, standard remediation
- Where
- 18 sites in France
- Volunteers
- 166 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
HIV Infections, HIV Seronegativity
A Phase I Study to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Antigen in Children Born to HIV-Infected Mothers
PRIMARY: To determine the safety of envelope recombinant proteins rgp120/HIV-1MN (Genentech) and rgp120/HIV-1SF2 (Chiron/Biocine) in infants who are of indeterminate HIV status born to HIV-infected women.
- Trial name
- NCT00000774
- Testing
- rgp120/HIV-1MN, rgp120/HIV-1 SF-2
- Where
- 37 sites in United States, Puerto Rico
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Overactive Bladder (OAB), Drug Delivery Systems
Transdermal Versus Oral Oxybutynin in Pediatric OAB
This is a prospective, randomized controlled clinical trial designed to compare the efficacy and safety of transdermal versus oral oxybutynin in children diagnosed with overactive bladder (OAB) who remain symptomatic despite…
- Conditions
- Overactive Bladder (OAB), Drug Delivery Systems, Anticholinergic Side Effects, Children and Adolescents, Boys and Girls
- Trial name
- NCT07081906
- Testing
- Oral Oxybutynin, transdermal oxybutinin
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Infant, Premature, Brain Injuries
Structural Brain Abnormalities in Children Born Prematurely: New Detection Methods and Clinical-Pathological Correlates
The purpose of the study is to detect structural brain changes using MRI and to correlate these findings with neurodevelopmental assessments in two-year old children previously enrolled in the NIH sponsored trial of inhaled…
- Trial name
- NCT00153855
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Prospective, Single-blind
Bacille Calmette Guérin Immunisation at Birth and Childhood Morbidity in Danish Children.
In high-income societies the use of health care and medication is steadily increasing. Children have high morbidity, many visits at the general practitioner, an increasing number of hospitalisations, and an increasing use of…
- Conditions
- Prospective, Single-blind, Clinical, Trial
- Trial name
- NCT01694108
- Testing
- BCG-vaccine (SSI)
- Where
- 3 sites in Denmark
- Volunteers
- 4,262 people
- Sponsor
- Lone Graff Stensballe
Attention Deficit Disorder With Hyperactivity
The Impact of Osmotic Release Oral Delivery System Methylphenidate (OROS MPH) Upon Family of Children and Adolescents With Attention Deficit Hyperactivity Disorder (ADHD)
The purpose of this study is to evaluate whether familial relationships and psychological status of participants or caregivers as well as Attention Deficit Hyperactivity Disorder (ADHD) symptoms of participants can be improved by…
- Trial name
- NCT00758160
- Testing
- OROS Methylphenidate
- Volunteers
- 296 people
- Sponsor
- Johnson & Johnson Taiwan Ltd
Child Allergy, Neurodevelopmental Disorders
A Prospective Birth Cohort of Infants With Allergy and Neurodevelopmental Disorders in China
In this study, a birth cohort was established to demonstrate the causal relationship between allergies and neurodevelopment disorders in infants and young children, and to find out the influencing factors of neurodevelopment…
- Trial name
- NCT06327906
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Qilu Hospital of Shandong University
Dental Caries
The Relation Between Pregnancy,Birth Outcome, Feeding , Oral Hygiene Habits and Early Childhood Caries Development.
200 children between ages 36 to 48 months will be invited for a regular dental examination Parameters to be investigated 1. Pregnancy history 2. Birth outcome 3. Child's general health 4. Feeding habits 5. Oral hygiene habits 6.
- Trial name
- NCT00334087
- Testing
- feeding habits
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Child Behavior Problem, Preterm
I-InTERACT Preterm Parenting
Many children born very preterm experience behavior problems, and existing resources for parenting these children are lacking. A pilot trial established the effectiveness of a preterm parenting intervention, I-Interact Preterm…
- Conditions
- Child Behavior Problem, Preterm, Parent-Child Relations, Parenting
- Trial name
- I2P-RCT (NCT06767293)
- Testing
- I-InTERACT Parenting Intervention (I2P) and coaching sessions, I-InTERACT Parenting Microlearning Intervention (I2P Micro) and coaching sessions, Internet Resources
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati