Clinical trials: Child Birth
Maternal Obesity Complicating Pregnancy, Birth,or Puerperium, Child Malnutrition
Addressing the Double Burden of Malnutrition in Guatemala
Globally, populations are experiencing increases in the double burden of malnutrition, commonly defined as maternal overweight/obesity and child stunting in the same household.
- Trial name
- NCT06750120
- Testing
- Family food ration, Optimal weight counseling, Enhanced Usual Care
- Where
- Guatemala
- Volunteers
- 1,532 people
- Sponsor
- Brigham and Women's Hospital
Birth Outcomes, Stunting
Uganda Birth Cohort Study
The UBC was a USAID-funded longitudinal prospective cohort study of pregnant women (n= 5030) aged 15-49 years from rural North and South-Western regions of Uganda, conducted between 2014 and 2016.
- Conditions
- Birth Outcomes, Stunting, Wasting, Anemia
- Trial name
- UBC (NCT04233944)
- Where
- United States
- Volunteers
- 5,044 people
- Sponsor
- Tufts University
Children Born After Assisted Reproductive Technologies, Health Status
Health Status of Children Born After Assisted Reproductive Technologies
The goal of this observational study is to study the features of psychophysical development and the morbidity patterns of children born after assisted pregnancy, and to identify the connection with the health status of mothers…
- Conditions
- Children Born After Assisted Reproductive Technologies, Health Status, Child Development
- Trial name
- NCT06094998
- Testing
- hemogram examination
- Where
- Kazakhstan
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Kazakhstan's Medical University "KSPH"
Infertility, IVF
Health of Frozen Transferred Versus Fresh Transferred Children
In order to give strong recommendation on the efficacy and safety of fresh versus frozen embryo transfer, we conduct this study in order to investigate the physical and mental development of children from fresh versus frozen…
- Trial name
- NCT04099784
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3, Physical development and General Health, Developmental Red flags
- Where
- Vietnam
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
Hepatitis B Infection, Congenital Malformation
Tenofovir Disoproxil Fumarate in Combination of Hepatitis B Vaccine for Preventing Hepatitis B Vertical Transmission
Immunoprophylaxis with two hepatitis B vaccinations following the hepatitis B immune globulin (HBIg) and hepatitis B vaccine at birth is largely effective in protecting infants from hepatitis B virus (HBV) infection.
- Conditions
- Hepatitis B Infection, Congenital Malformation, Birth Defect, Viremia
- Trial name
- NCT03476083
- Testing
- Tenofovir Disoproxil Fumarate (TDF) 300 mg oral daily.
- Where
- 7 sites in China
- Volunteers
- 280 people
- Sponsor
- New Discovery LLC
Type 1 Diabetes
Post Market Registry for the Omnipod 5 System in Children and Adults With Type 1 Diabetes
This is a decentralized observational clinical registry to collect real-world evidence related to the safety and effectiveness of the Omnipod 5 system in children and adults with Type 1 Diabetes.
- Trial name
- NCT06144554
- Testing
- Omnipod 5
- Where
- United States
- Volunteers
- 2,200 people
- Sponsor
- Insulet Corporation
Low Birth Weight
Community Kangaroo Mother Care for Improving Child Survival and Brain Development in Low Birth Weight Newborns
While newborn and child survival remains a priority, optimal development of survivors is receiving increasing attention. Interventions that impact both survival and development should be prioritized for action.
- Trial name
- CKMC-DEV (NCT02631343)
- Testing
- KMC, Essential newborn care
- Where
- India
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Society for Applied Studies
Zinc Deficiency, Diarrhea
Water-based Zinc Intervention Trial in Zinc Deficient Children
The overall aim of this trial is to determine whether the use of the household-based water treatment device Life Straw Family (LSF) can be an effective strategy to improve zinc status and health status of vulnerable populations…
- Trial name
- NCT01472211
- Testing
- zinc enriching filter (LifeStrawFamily), disinfection tablets
- Where
- Benin
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Plasmodium Falciparum Malaria
Superiority of ArTiMist Versus Quinine in Children With Severe Malaria
The purpose of this study is to demonstrate that ArTiMist (sublingual artemether spray) is better than intravenous quinine in reducing parasite counts by >= 90% within 24 hours after the start of treatment in children with severe…
- Trial name
- NCT01258049
- Testing
- Artemether Sublingual Spray, Quinine
- Where
- 3 sites in Burkina Faso, Ghana and 1 more
- Volunteers
- 151 people
- Sponsor
- Proto Pharma Ltd
Pediatric Traumatic Brain Injury
Overcoming Membrane Transporters to Improve CNS Drug Delivery - Improving Brain Antioxidants After Traumatic Brain Injury
The overall purpose of this research study is to investigate the safety of pharmacological therapies that may potentially improve pediatric outcomes after traumatic brain injury.
- Trial name
- Pro-NAC (NCT01322009)
- Testing
- Probenecid and N-acetyl cysteine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Pittsburgh
Caesarean Delivery
Regenerative Effects of Birth Material Derived Extracellular Vesicles
Stem cells offer great hope for a wide range of disorders, including age-related brain disease such as dementia. Mesenchymal stem cells (MSCs) are special types of adult stem cells found in various tissues like the umbilical…
- Trial name
- ReGAIN (NCT06866184)
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Bronchopulmonary Dysplasia
Pulmonary MRI of Ex-preterm Children With and Without BPD To Understand Risk of Emphysematous Changes
Health Issue: Bronchopulmonary dysplasia (BPD), a chronic lung disease, is the most common complication of being born premature. Damage to the still developing lung stops the normal formation of the alveoli.
- Trial name
- PICTURE (NCT02921308)
- Where
- 4 sites in Canada
- Volunteers
- 45 people
- Sponsor
- Children's Hospital of Eastern Ontario
Congenital Adrenal Hyperplasia, Hyperplasia
Subcutaneous Hydrocortisone Children With Congenital Adrenal Hyperplasia
This is an open-label, non-randomized, single arm proof-of concept feasibility trial comparing standard oral hydrocortisone (HC) treatment with a six-week intervention of interval bolus delivery (pulsatile) of subcutaneous (SQ)…
- Conditions
- Congenital Adrenal Hyperplasia, Hyperplasia, Adrenal Hyperplasia, Congenital Disorders
- Trial name
- NCT03718234
- Testing
- Subcutaneous hydrocortisone
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Minnesota
Metabolic Syndrome
Risk Factors Related to Metabolic Syndrome in School-aged Children Who Were Born Preterm
This is a follow-up cohort study of 8 years old children born preterm at Seoul National University Children's Hospital in Korea from 2008-2009.
- Trial name
- NCT02746887
- Testing
- Preterm/term cohort
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Unilateral Cataract Extraction, Congenital Cataract
A Randomized Study in Children Ages Birth Through Three Years Undergoing Unilateral Cataract Extraction With or Without Lens Replacement
The purpose of this study is to evaluate the effect of OMS302 compared to phenylephrine when administered in irrigation solution during cataract extraction on intraoperative pupil diameter, acute postoperative pain, and safety in…
- Trial name
- ILR7 (NCT02132312)
- Testing
- OMS302, Phenylephrine HCl
- Where
- 11 sites in United States
- Volunteers
- 78 people
- Sponsor
- Omeros Corporation
Traumatic Brain Injury, Cerebral Palsy
Real World Outcomes of Intranasal MuSE Exosomes and Stem Cells in Neurological Regenerative Therapy
This prospective observational study collects real world data on participants receiving regenerative therapies administered internationally and delivered intranasally via the Kurve Therapeutics ViaNase device.
- Conditions
- Traumatic Brain Injury, Cerebral Palsy, Hypoxic Ischemic Encephalopathy, Neurologic Disorders
- Trial name
- MuSE-INSIGHT (NCT07521384)
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Healing Hope International
Autism Spectrum Disorder
Improving the Part C Early Intervention Service Delivery System for Children With ASD
Despite strong consensus that early, specialized intervention for children with autism spectrum disorder (ASD) can have a dramatic impact on outcomes, the public health system's capacity to provide such services is severely…
- Trial name
- NCT05114538
- Testing
- Reciprocal Imitation Training
- Where
- 4 sites in United States
- Volunteers
- 440 people
- Sponsor
- Rush University Medical Center
HIV Infections
Voluntary HIV Counseling, Testing, and Medication for Pregnant Women to Prevent Mother-to-Child HIV Transmission
Voluntary HIV counseling and testing (VCT) and anti-HIV drugs for pregnant women and their newborns decrease rates of mother-to-child transmission (MTCT) of HIV.
- Trial name
- NCT00084045
- Testing
- Intrapartum HIV counseling/testing, Postpartum HIV counseling/testing
- Where
- 2 sites in South Africa
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Premature Birth
Prediction Tool for Premature Labour and Neonatal Outcome
A register and prediction model will be developed to predict the outcome of preterm labour and birth.
- Trial name
- PRETURN (NCT03405116)
- Where
- Belgium
- Volunteers
- 2,037 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Child Maltreatment, Domestic Violence
Efficacy of Group Attachment Based Intervention for Vulnerable Families
The study examines the effectiveness of parent-child Group Attachment Based Intervention (GABI) in reducing risk of maltreatment in infants and toddlers compared with parenting skills classes.
- Trial name
- NCT01641744
- Testing
- Systematic Training for Effective Parenting (STEP), Group Attachment Based Intervention (GABI)
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine