Clinical trials: Child Immunization
Meningococcal Immunisation (Healthy Volunteers)
Study of a Quadrivalent Meningococcal Conjugate Vaccine as a Single Dose Compared With a Single Dose of a Meningococcal Reference Vaccine in Children, Adolescents, and Adults 2 to 55 Years of Age
Primary Objective: To demonstrate the non-inferiority of the antibody responses to meningococcal serogroups A, C, Y, and W following the administration of a single dose of Meningococcal Polysaccharide (Serogroups A, C, Y, and W)…
- Trial name
- NCT04368429
- Testing
- Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate Vaccine (MenACYW Conjugate Vaccine), Meningococcal (Groups A, C, Y and W 135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine
- Where
- 4 sites in Japan
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Sanofi
Influenza, Human
Childhood Influenza Immunisation Invitation Trial in Schools
This study will investigate whether influenza vaccine uptake by school-age children (in school-based clinics) can be increased by making behavioural-insight informed changes to the invitation process which encourage parents to…
- Trial name
- NCT02883972
- Testing
- Intervention letter, Control letter, Reminder
- Volunteers
- healthy volunteers welcome
- Sponsor
- Public Health England
Pertussis, Diphtheria
Maternal Immunization With Tetanus Toxoid, Reduced Diphtheria Toxoid, Reduced-dose (2 µg) Recombinant Pertussis Vaccine (TdaP2gen) and Its Effect on the Immune Response in Thai Infants up to 15-18 Months Old
Pertussis remains a major global public health problem. In Thailand, pertussis vaccination is recommended during pregnancy at 20-32 weeks' gestation, together with routine childhood diphtheria-tetanus-pertussis vaccination…
- Conditions
- Pertussis, Diphtheria, Tetanus, Vaccine-Preventable Diseases
- Trial name
- M-PRIME (NCT07621341)
- Testing
- Maternal TdaP2gen vaccine, Infant Acellular Pertussis-containing Vaccine, Infant Whole-cell Pertussis-containing Vaccine
- Where
- Thailand
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Atopic Dermatitis
Immune Response to Varicella Vaccination in Children With Atopic Dermatitis
Atopic dermatitis (AD) causes people to be susceptible to skin infection and inflammations. The purpose of this study is to determine the immune response to chicken pox vaccine in children with or without AD who received the…
- Trial name
- NCT00406081
- Where
- 2 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Seasonal Influenza Vaccination
Seasonal Influenza Vaccination Reminders for Children With High-risk Conditions
The objective of this study was to assess the feasibility and effectiveness of using a statewide immunization information system (IIS) to send seasonal influenza vaccine reminders from Local Health Departments (LHDs), targeting…
- Trial name
- NCT01431183
- Testing
- Mailed influenza vaccination reminder notice
- Where
- United States
- Volunteers
- 3,618 people
- Sponsor
- University of Michigan
Behavior Change
Chatbot-delivered Theory-based Online Intervention in Increasing Seasonal Influenza Vaccination Uptake Among Children Aged 3-6 Years
This randomized controlled trial will compare the efficacy of a Chatbot-delivered stage-of-change-tailored online intervention versus a Chatbot-delivered non-stage-of-change-tailored online intervention for mothers in increasing…
- Trial name
- NCT07687719
- Testing
- Stage-of-change-tailored intervention, Non-stage-of-change-tailored intervention
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Acute Upper Respiratory Infection, Acute Lower Respiratory Tract Infection
Impact of Introduction of PHiD-CV for Nunavik Children, Quebec, Canada
The objective of this study is to document the residual burden of acute upper respiratory infections (AURIs), acute lower respiratory infections (ALRIs), otitis media (OMs) and auditory functional and anatomical abnormalities in…
- Conditions
- Acute Upper Respiratory Infection, Acute Lower Respiratory Tract Infection, Otitis Media (OM), Invasive Pneumococcal Disease, Protection Against
- Trial name
- Nunavik2 (NCT01694329)
- Where
- Canada
- Volunteers
- 1,420 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Influenza
From Innovation to Solutions: Childhood Influenza Vaccination Planning
The purpose of this study is to increase childhood influenza vaccination rates using the FDA licensed influenza vaccines according to national guidelines in a randomized cluster trial in which primary care offices are randomized…
- Trial name
- NCT01664793
- Testing
- 4 Pillars Immunization Toolkit
- Where
- United States
- Volunteers
- 87,665 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Celiac Disease
Celiac Disease Prevention
Celiac disease is an autoimmune disease induced by wheat gluten. Destruction of epithelial cells and microvilli on gut mucosa is causing a "flat mucosa" and an absorption defect.
- Trial name
- NCT00617838
- Testing
- Optimal gluten introduction
- Where
- Finland
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Perinatal
Study on the Fetal Safety of New Coronavirus Vaccination for Couples During the Peri-pregnancy Period
All the pregnant women and newborns of both or one of the couples who gave birth in Ditan hospital were collected as the observation group, and the pregnant women and newborns of both husband and wife who gave birth in our…
- Trial name
- NCT05125770
- Testing
- New crown vaccine
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beijing Ditan Hospital
HPV, Complex Intervention
Schoolbased HPV-counselling and -Vaccination
This study is designed as a non-randomized implementation study consisting of a user-centered school-based HPV-counselling and HPV-vaccination (HPVV) program.
- Trial name
- NCT05681169
- Testing
- School-based HPV-counselling and HPV-vaccination.
- Where
- Denmark
- Volunteers
- 640 people
- Sponsor
- University of Aarhus
Malaria
A Study to Assess the Safety and Immunogenicity of a Vaccine Against Malaria in Healthy Children Aged 5-60 Months
The purpose of this study is to evaluate the safety and immunogenicity of reduced antigen doses and alternative vaccination regimes for RTS,S/AS01E in healthy children aged 5-60 months in a malaria-endemic area.
- Trial name
- NCT07036159
- Testing
- RTS,S/AS01E vaccine
- Where
- 2 sites in Rwanda
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Influenza Vaccines
Vaccine Chatbot for Improving Influenza Vaccination Uptake
This study aims to assess the impact of a vaccine chatbot on improving influenza vaccination uptake among children aged between 6 and 59 months through a cluster randomized trial.
- Trial name
- NCT06657573
- Testing
- An AI-enabled chatbot tailored for influenza vaccine consultation
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Fudan University
Malaria
Safety, Tolerability and Efficacy of PfSPZ Vaccine in Healthy Children and Infants 5 Months - 9 Years Living in Kenya
This study will be conducted in Siaya County in Nyanza Province, western Kenya. Healthy children aged 5 months through 9 years of age living within approximately 10 km of the study clinic(s) (Siaya County Referral Hospital, or…
- Trial name
- NCT02687373
- Testing
- PfSPZ Vaccine, Normal Saline
- Where
- Kenya
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- Sanaria Inc.
Orthomyxoviridae Infection, Influenza
Study of Inactivated, Split-Virion Influenza Vaccine Compared With Standard Fluzone Vaccine in Infants and Children
Primary Objective: To evaluate for each influenza strain the non-inferiority of Investigational Fluzone vaccine to the standard Fluzone® vaccine in healthy subjects aged 6 to 35 months or 3 to 8 years.
- Conditions
- Orthomyxoviridae Infection, Influenza, Myxovirus Infection
- Trial name
- NCT00391391
- Testing
- Split, Inactivated, Trivalent Influenza Vaccine, Split, Inactivated, Trivalent Influenza Vaccine ( Fluzone® 2006/2007 Formulation)
- Where
- 19 sites in United States
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Sanofi
Encephalitis, Tick-borne
Study to Investigate the Seropersistence of TBE Virus Antibodies Approx. 3 Years After a Booster Vaccination With FSME-IMMUN 0.25 mL JUNIOR in Children
The objective of this study is to assess the TBE antibody persistence approximately three years after administration of a TBE booster vaccination with FSME-IMMUN 0.25 ml Junior in children who received either 0.25 mL or 0.5 mL…
- Trial name
- NCT00163618
- Testing
- Formaldehyde inactivated, sucrose gradient purified TBE virus antigen, strain Neudörfl
- Where
- 4 sites in Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pfizer
Communicable Diseases
Reducing Delay of Vaccination in Children Study
This trial will assess the effectiveness of a tailored message intervention on decreasing infant undervaccination.
- Trial name
- REDIVAC (NCT02665013)
- Testing
- Tailored, Untailored
- Where
- United States
- Volunteers
- 824 people
- Sponsor
- Kaiser Permanente
Malnutrition Severe, Vaccination
OptiMAx Will Test Whether SQ-LNS Incentivises Vaccination Uptake in Rural Chad and Niger, With a Cost Effectiveness Analysis. It Will Also Look at Whether Having Received SQ-LNS Before Becoming Malnourished Leads to Better Outcomes for Children Treated Under the OptiMA Protocol.
Malnutrition and infectious disease form a vicious circle, posing a double threat to vulnerable children in low- and middle-income countries.
- Trial name
- OptiMAx (NCT07592260)
- Testing
- small quantity lipid-based supplement (SQ-LNS)
- Where
- 2 sites in Chad, Niger
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Alliance for International Medical Action
Placebo Analgesia, Pediatric Pain
Applying a Small Procedure Prior to Injection/Vaccination Reduces Pain in Children
In this proposed study, the investigators aim to apply a minor procedure prior to a treatment that induces pain (e.g., injection/vaccination) to help manage pediatric pain.
- Conditions
- Placebo Analgesia, Pediatric Pain, Vaccination
- Trial name
- NCT06313788
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Lingnan University
Japanese Encephalitis
Immunogenicity of a JE-CV as a Booster Dose After a Primary Vaccination With SA14-14-2 Vaccine
The objective of this study is to measured the Geometric mean titer (GMT) of Japanese Encephalitis neutralizing antibody and proportion of seroprotection among the children who received a booster dose of JE-CV after the first…
- Trial name
- NCT02602652
- Testing
- a live attenuated chimeric JE vaccine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University