Clinical trials: Child Immunization
Infections, Meningococcal, Meningococcal Vaccines
Persistence and Booster Study of GSK Biologicals' Meningococcal Vaccine (GSK134612) in Healthy Children
The purpose of the study is to evaluate the persistence of the immune response of GSK134612 vaccine up to 68 months after vaccination in the primary vaccination study (NCT number = NCT00674583) of 2 to 10 year old subjects.
- Trial name
- NCT01266993
- Testing
- Nimenrix (GSK134612 vaccine), Menjugate
- Where
- 24 sites in France, Germany
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Infant and Young Child Feeding
Partnering With Media and Vaccination Program to Improve Infant and Young Child Feeding
Infant and young child feeding (IYCF) is a key determinant of under-nutrition and overweight in young children. In Mexico, breastfeeding extends well into the second half of infancy, but animal-source foods, cereals, and legumes…
- Trial name
- NCT01405755
- Testing
- Appropriate complementary feeding messages
- Where
- Mexico
- Volunteers
- 420 people
- Sponsor
- University of South Carolina
Mortality, Vaccines
The Effect on Overall Mortality of a National Policy of Limiting Measles Vaccination to Children Below 12 Months of Age
The national Expanded Programme on Immunization (EPI) in Guinea-Bissau focuses its efforts exclusively on children below 12 months of age; children who have reached 12 months of age are no longer entitled to vaccines through the…
- Trial name
- MVEPI (NCT01306006)
- Testing
- Providing measles vaccine for all children 9-35 months who have not yet received a routine measles vaccine
- Where
- Guinea-Bissau
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Maternal Health, Child Health
Assessing the Impact of Mobile Phone Technology to Improve Health Nutrition and Population (HNP) Service Utilization in Rural Bangladesh Through Pilot Intervention
1. Burden: In global perspective, it is estimated that the lives of 150,000 women could be saved each year worldwide with access to sufficient family planning services.
- Conditions
- Maternal Health, Child Health, Vaccination, Family Planning Services
- Trial name
- NCT03189004
- Testing
- Impact of Mobile Phone Technology to Improve Health Nutrition and Population (HNP) Service Utilization in Rural Bangladesh
- Where
- Bangladesh
- Volunteers
- 5,280 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Vaccine Hesitation
Vaccination Hesitation in Expectant Mothers
The aim of this study is to increase the awareness of vaccination with the training on childhood vaccine hesitancy given to expectant mothers by a nurse during pregnancy.
- Trial name
- NCT06530875
- Testing
- training on hesitations regarding childhood vaccinations
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Influenza
Swine Flu (Influenza A H1N1) Follow on Vaccine Study
In 2009 the World Health Organization (WHO) declared the Influenza A H1N1 (swine 'flu) outbreak the first global pandemic of this century.
- Trial name
- NCT01239537
- Testing
- Seasonal Flu vaccine
- Where
- 5 sites in United Kingdom
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- University of Oxford
HPV Vaccine
Strengthening HPV Immunization Through EPI Leveraged Delivery
This is a randomized observer-blind placebo-controlled proof-of-concept study with the aim to assess the safety and tolerability, and the immunogenicity of a bivalent HPV vaccine administered in healthy infants and toddlers (9…
- Trial name
- SHIELD (NCT07377656)
- Testing
- HPV vaccine, Measles and rubella Vaccine
- Where
- Ghana
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- International Vaccine Institute
Immune Responses, Antibiotic Treatment
The Effects of Antibiotic Exposure in Early Infancy on Vaccine Responses
This prospective cohort study will include 200 term children born in Landspitali University Hospital in Iceland. The cohort will be divided into four groups according to antibiotic exposure of which one is the control group.
- Trial name
- NCT06079606
- Testing
- Antibiotic treatment
- Where
- Iceland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Landspitali University Hospital
Type 1 Diabetes
A Study to Evaluate Pneumococcal Polysaccharide Vaccine Effectiveness in Children With Type 1 Diabetes
The purpose of this study is to determine if children with type 1 diabetes have adequate immune response to PPSV23 vaccination and to assess factors affecting immune response.
- Trial name
- NCT04481243
- Testing
- Pneumovax 23- pneumococcal polysaccharide, Blood draw
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Mayo Clinic
Tetanus, Acellular Pertussis
Immunogenicity and Safety of Kinrix + (Measles Mumps Rubella) MMR Vaccine With and Without Varicella Vaccine in Healthy Children 4-6 Years
The purpose of the study is to evaluate the immunogenicity and safety of Kinrix when co-administered with varicella (Varivax® [varicella virus vaccine live], Merck and Company) and (measles mumps rubella) MMR vaccines, compared…
- Conditions
- Tetanus, Acellular Pertussis, Diphtheria
- Trial name
- NCT00871117
- Testing
- GSK Biologicals'Kinrix®, Merck and Company's MMRII, Merck and Company's Varivax
- Where
- 11 sites in United States
- Volunteers
- 478 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Influenza Vaccine, Influenza
Factors Associated With Parental Observation of Side Effects Following the Child Flu Vaccine
This study investigates whether there are psychological predictors of parental perception of side-effects following vaccination with the child flu vaccine.
- Trial name
- NCT02909855
- Testing
- No intervention
- Where
- 11 sites in United Kingdom
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- King's College London
Infections, Streptococcal
Immune Memory Evaluation in Children Following a Primary Vaccination With Pneumococcal Conjugate Vaccines.
To evaluate the immunological memory against pneumococcal vaccine serotypes in children primed with conjugate vaccines by administering a booster dose of plain polysaccharide vaccine.
- Trial name
- NCT00333450
- Testing
- Pneumococcal vaccine
- Where
- 30 sites in Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Encephalitis
Immunogenicity of a Live Attenuated Chimeric JE Vaccine (IMOJEV) as a Booster Dose in Thai Children Primed With CD.JEVAX
This study was undertaken to assess the immunogenicity and safety of a booster dose of a live attenuated chimeric Japanese Encephalitis vaccine (JE-CV) after primary vaccination with SA14-14-2 in Thai children aged 1 to <5 years.
- Trial name
- NCT02526550
- Testing
- Live attenuated chimeric Japanese Encephalitis vaccine, Inactivated Hepatitis A vaccine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Mother's Anxiety, Child's Pain
The Study Aims to Determine the Effect of Using Animal-shaped Magic Mirrors During Vaccination in Children Aged 1-4 Years on the Child's Pain and the Mother's Anxiety.
Vaccination is one of the most common invasive procedures performed on healthy infants and children. These procedures can cause pain and fear in children and anxiety in parents.
- Trial name
- MAGİC MİRROR (NCT07535151)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Malaria Falciparum, Malaria Infection
Age De-escalation Safety Trial of PfSPZ-LARC2 Vaccine in Burkina Faso
This is a first-in-humans randomized, double-blind, placebo-controlled, age de-escalation Phase 1 trial of Plasmodium falciparum (Pf) late liver stage-arresting replication-competent (LARC) sporozoite (SPZ) malaria vaccine…
- Trial name
- NCT06652737
- Testing
- PfSPZ-LARC2 Vaccine
- Where
- Burkina Faso
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sanaria Inc.
Influenza, Human, Immune Response
Immunologic Response to Influenza Vaccination in Children and Adolescents
The purpose of this study is to evaluate immunologic response to different types of influenza vaccine among children/adolescents/young adults 4-20 years of age.
- Trial name
- NCT03614975
- Testing
- Flucelvax inactivated influenza vaccine, Fluzone inactivated influenza vaccine
- Where
- 2 sites in United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Richard Zimmerman MD
Systems Biology, Early Gene
Systems Biology of Vaccination for EV71 Vaccine in Humans
Recently, an inactivated vaccine (vero cell) against EV71 has been investigated in Phase 1 and Phase 2 clinical trials. Data from these trials showed that the EV71 vaccine has good safety profile and was immunogenic.
- Conditions
- Systems Biology, Early Gene, EV71 Vaccine
- Trial name
- NCT01679665
- Testing
- 320U /0.5ml
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
Immunization Rates
Comparative Effectiveness Trial of Two Reminder/Recall Methods to Increase Immunization Rates in Young Children
The purpose of this study is to determine if a collaborative centralized population-based reminder/recall intervention is more effective than a traditional practice-based reminder/recall intervention at increasing immunizations…
- Trial name
- NCT01557621
- Testing
- Collaborative Pop-Based R/R: Phone/Mail Group, Collaborative Pop-Based R/R: Mail-Only Group, Practice-based Recall
- Where
- 2 sites in United States
- Volunteers
- 68,000 people
- Sponsor
- University of Colorado, Denver
Healthy Participants
Trial of Antibody Responses by Vitamin Supplementation
Streptococcus pneumoniae, commonly called pneumococcus, can cause a wide range of diseases in children from mild ear infections to deadly pneumonia or meningitis. Vaccination is currently the single best way to protect children.
- Trial name
- NCT03859687
- Testing
- Vitamin A supplementation, No vitamin A supplementation
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
HPV Infection, Hiv
HPV Vaccination in HIV Infected and HIV Uninfected Adolescents in Eswatini
This is a multi-site, open-label non-inferiority study of the 9vHPV vaccine among a population of children, adolescents and young women living with HIV in Eswatini.
- Conditions
- HPV Infection, Hiv, HPV Vaccine
- Trial name
- NCT04982614
- Testing
- Gardasil ® 9
- Where
- 5 sites in Eswatini
- Volunteers
- 1,403 people
- Sponsor
- Columbia University