Clinical trials: Child Malnutrition
Severe Acute Malnutrition
Gastrointestinal Tolerance of Under-five Children With Severe Acute Malnutrition to ONS Compared to F-75/F-100
The primary outcome of the study is to identify gastrointestinal tolerance of under-five children with severe acute malnutrition to ready-to-drink high energy (1.5 kcal/ml) and standard energy (1 kcal/ml) oral nutrition…
- Trial name
- NCT04715204
- Testing
- High Energy Oral Nutrition Supplement, Standard Energy Oral Nutrition Supplement, Formula-75/Formula-100
- Where
- 2 sites in Indonesia
- Volunteers
- 108 people
- Sponsor
- Universitas Indonesia
Overweight and Obesity, Stunted Growth
Intervention in Children With Malnutrition
Malnutrition is an epidemiologic problem with high prevalence in Mexico. Mexican children present a double burden of malnutrition characterized by the coexistence of undernutrition and micronutrient deficiency alongside excess…
- Conditions
- Overweight and Obesity, Stunted Growth, Malnutrition, Child, Nutrient Deficiency
- Trial name
- NCT04915638
- Testing
- Experimental intervention group with enriched cookies
- Where
- Mexico
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Marta Alicia Menjivar Iraheta
Hypophosphatasia (HPP)
Extension Study of Protocol ENB-006-09 - Study of Asfotase Alfa in Children With Hypophosphatasia (HPP)
This clinical trial studies the long term safety and efficacy of asfotase alfa in children with HPP who completed Study ENB-006-09 (NCT00952484).
- Trial name
- NCT01203826
- Testing
- Asfotase Alfa
- Where
- 2 sites in United States, Canada
- Volunteers
- 12 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Malnutrition
Comparison of the Effect of Two Treatments on the Nutritional and Micronutrient Status of Malnourished Children
The purpose of this study is to measure the impact of a fortified food on the nutritional and micronutrient status of malnourished children, compared with milk.
- Trial name
- NCT01643187
- Testing
- Beverage fortified with 21 vitamins and minerals, Lactose-free milk
- Where
- Guatemala
- Volunteers
- 1,000 people
- Sponsor
- Association for the Study and Prevention of HIV/AIDS
Environmental Enteric Dysfunction, Zinc Deficiency
Effects of EED on Zn Absorption and Retention in Children From a Standard Dose
The overall objective is to determine the impact of EED on zinc absorption and homeostasis, and its impact on the absorptive capacity of vitamin A absorption of young children (18-24 months of age) in an austere setting with high…
- Conditions
- Environmental Enteric Dysfunction, Zinc Deficiency, Vitamin A Deficiency
- Trial name
- ZEED1 (NCT02760095)
- Testing
- 3 mg zinc sulfate supplement, 0.5 mg of 13C10-retinyl-acetate
- Where
- 2 sites in United States, Bangladesh
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Malnutrition
Validation of the STAMP Screening Tool
Insufficient nutritional intake, with or without concomitant morbidity, leads to weight loss or insufficient weight gain, is related to an increase in morbidity and mortality and exposes the child to medical complications.
- Trial name
- STAMP2 (NCT01584310)
- Testing
- questionnaire STAMP and dietary, No STAMP using
- Volunteers
- 60 people
- Sponsor
- Rabin Medical Center
Immunity to Polio Vaccines in Malnourished Infants, Immunity to Polio Vaccines in Non-malnourished Infants
IPV in Moderate to Severe Chronic Malnourished 9-12 Month Old Children in Karachi.
Chronic malnutrition is associated with lack of effective gut immunity which is a possible explanation for why we see polio cases among a proportion of children who have received 7 or more doses of OPV.Our proposed idea is to…
- Trial name
- MIPV (NCT01695798)
- Testing
- Injectable polio vaccine and Bivalent oral polio vaccine
- Where
- Pakistan
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Malnutrition, Child, Growth; Stunting, Nutritional
Samaki Salama: Small-scale Fisheries for Healthy Nutrition and Ecosystems
The purpose of this study is to test the effectiveness of a bundled intervention to address malnutrition and its intersections with nutrition security and fisheries sustainability in Kilifi, Kenya.
- Trial name
- NCT05254444
- Testing
- Social marketing, social marketing + gear modification
- Where
- Kenya
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Malnourished Children
Effects of Channa Striata Extract on Intestinal Inflammation and Nutritional Status in Malnutritional Toddlers After Albendazole Therapy in South Bangka District
The goal of this clinical trial is to learn if intervention with channa striata extract or inbumin forte sachet as a food supplement can improve intestinal damage and nutritional status in malnourished children aged 1.5-5 years.
- Trial name
- Striatin1 (NCT06933862)
- Testing
- Striatin
- Where
- 2 sites in Indonesia
- Volunteers
- 122 people
- Sponsor
- Universitas Indonesia
Child Nutrition Disorders
A Nutrition/Hygiene Education Program for the Prevention of Child Malnutrition in Rural Kenya
This study will determine if an education program about hygiene and child feeding practices, taught by local village community health workers, will improve child growth and decrease the prevalence of childhood malnutrition in a…
- Trial name
- NCT01679535
- Testing
- nutrition and hygiene education
- Where
- United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Malnutrition, Child, Obesity
Keiki (Pediatric) Produce Prescription (KPRx) Program Hawaii
Children living in food-insecure homes, defined as at some time during the last year their household not having enough food, money, or resources to feed the family experience low intake of fresh fruits and vegetables (FV), and a…
- Conditions
- Malnutrition, Child, Obesity, Food Selection, Nutrition Poor
- Trial name
- KPRxHawaii (NCT05442424)
- Testing
- Produce Voucher, Wait-List Control
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Hypophosphatasia (HPP)
Safety and Efficacy of Asfotase Alfa in Juvenile Patients With Hypophosphatasia (HPP)
This clinical trial studied the safety and efficacy of asfotase alfa in children with HPP compared to a historical control group.
- Trial name
- NCT00952484
- Testing
- asfotase alfa
- Where
- 2 sites in United States, Canada
- Volunteers
- 13 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Malnutrition, Wasting
Nutritional Impact of Moringa Oleifera Leaf Supplementation in Mothers and Children
Studies to date on the effects of Moringa oleifera in diabetes and anemia and animal studies that examine the utility of moringa for increased milk and litter yield are of small scale, however high-quality large-scale placebo or…
- Conditions
- Malnutrition, Wasting, Growth Failure
- Trial name
- NCT04587271
- Testing
- Moringa oleifera (high dose), Moringa oleifera (low dose)
- Where
- 2 sites in Kenya
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Suzanna L Attia
Child Malnutrition, Infant Morbidity
Effectiveness of Nutritional Supplementation in Preventing Malnutrition in Children With Infection in Karamoja, Uganda
The purpose of this study is to determine whether 14 days nutritional supplementation with Ready to use therapeutic Food (RUTF) or micronutrients alone to children having an infection will prevent malnutrition and reduce the…
- Trial name
- MSF-nutcon03 (NCT01497236)
- Testing
- Dietary Supplement: Nutrition supplement with RUTF or MNP
- Where
- Uganda
- Volunteers
- 2,202 people, healthy volunteers welcome
- Sponsor
- Medecins Sans Frontieres, Spain
Malnutrition
Food and Agricultural Approaches to Reducing Malnutrition
The aim of this study is to evaluate the potential of reducing young child undernutrition in low-income countries through an integrated program that trains women's groups in agriculture, nutrition, child care and hygiene.
- Trial name
- FAARM (NCT02505711)
- Testing
- Homestead Food Production program
- Volunteers
- 2,705 people, healthy volunteers welcome
- Sponsor
- Sabine Gabrysch
Malnutrition
Malnutrition and Outcome in Hospitalized Children in Europe
Malnutrition in children has even more severe consequences on disease course and long-term health than malnutrition in adults. According to prior studies, malnutrition affects about 15-30 % of hospitalized children in Europe…
- Trial name
- NCT01132742
- Where
- 14 sites in Croatia, Denmark and 9 more
- Volunteers
- 2,567 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Severe Acute Malnutrition
Evaluating RISQ System Implementation in Acutely Malnourished Children in Chad (CRIMSON)
The purpose of this study is to evaluate the effect of the Responses to Illness Severity Quantification (RISQ) system implementation on mortality and processes of care in a nutritional program treating children 6 to 59 months of…
- Trial name
- CRIMSON (NCT06123390)
- Testing
- The Responses to Illness Severity Quantification (RISQ) System
- Where
- Chad
- Volunteers
- 14,671 people
- Sponsor
- The Hospital for Sick Children
Vitamin D Deficiency, Dental Caries
Maternal Vitamin D Levels in Pregnancy and Dental Caries in Children
The main aim of this study is to investigate potential associations between maternal pre- and postnatal vitamin D level and oral health outcomes (caries and developmental defects of enamel) in their children at 7-9 years of age.
- Conditions
- Vitamin D Deficiency, Dental Caries, Dental Enamel Hypoplasia
- Trial name
- NCT03273725
- Testing
- Dental examination including taking a saliva sample.
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Tannhelsetjenestens Kompetansesenter Midt-Norge
Malnutrition in Pregnancy, Preterm Birth
Improving Cognition and Gestational Duration With Targeted Nutrition
The goal of this clinical trial is to test (1) a novel maternal ready-to-use supplementary food and (2) a novel cognitive behavioral therapy intervention in undernourished Sierra Leonean women.
- Conditions
- Malnutrition in Pregnancy, Preterm Birth, Child Development, Postpartum Depression
- Trial name
- COGENT (NCT05949190)
- Testing
- M-RUSF+ (Maternal Ready-to-Use Supplementary Food + DHA/EPA/choline), M-RUSF (Maternal Ready-to-Use Supplementary Food), Azithromycin
- Where
- 10 sites in Sierra Leone
- Volunteers
- 1,660 people
- Sponsor
- Washington University School of Medicine
Malnutrition, Worm Infestation
Deworming and Vitamin A (DEVTA) Prepilot Study
Background. More than a third of the world's population is infected with intestinal nematodes. A majority of these infections occur in children.
- Conditions
- Malnutrition, Worm Infestation, Under-Fives
- Trial name
- NCT00396500
- Testing
- Albendazole (400 mg) and/or Vitamin a
- Where
- India
- Volunteers
- 4,000 people
- Sponsor
- King George's Medical University